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MAPPAEHPARSPSRAELLAALSIAIDLGLGQPAEHMLRSAVIATRIAERLGLDRPQRDCCYYTALIMWIG CHADSHEYAHWFGDDIAVRHDSYLVDWTGLPYLRFLMANTGRGQPLLHRLSLMATLLADARGQISQLIHS HCASAGMLADRLGVSAEVQSALGSTFERYDGGGLPGGVGGDDIPLPMRVAQLADMVEVHHRAYGVDGAVA MARSRRGGQFDPRVVDAFTADAVTVLSVPAPGDAWTVALREAPDYGERLHGAELDALLVALGDFVDLKCP FTLGHSRAVAELAAGAAAVVGLDADTVTVVRRAGHLHDLGRIGVSNQIWSKPSSLTARELERVRLHPYLT VRILSQVGGLDAVAQVAGNHHEYLDGSGYPRGLPAAALSLPDRLLAAAVAYQSALEPRPYRDPLPATSAA ARLRERVREGRLDEVAVEAVLQAAGHRARGHSPRPGGLTPREIEVLCLVARGASNKEIAATLGISGKTAR NHVERTYAKIGATNRIGASMFALNHGLVAPA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2058 | - | - | 100% (521) | metal dependent phosphohydrolase |
| M. vanbaalenii PYR-1 | Mvan_3766 | - | 3e-12 | 38.30% (94) | response regulator receiver protein |
| M. vanbaalenii PYR-1 | Mvan_5522 | - | 1e-11 | 35.37% (147) | two component LuxR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2515c | - | 3e-10 | 34.86% (109) | LuxR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4288 | - | 0.0 | 82.92% (521) | metal dependent phosphohydrolase |
| M. tuberculosis H37Rv | Rv2488c | - | 4e-10 | 34.86% (109) | LuxR family transcriptional regulator |
| M. leprae Br4923 | MLBr_01753 | - | 4e-08 | 39.73% (73) | putative transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1522 | - | 6e-12 | 34.93% (146) | putative two-component system response regulator LuxR |
| M. marinum M | MMAR_3959 | - | 2e-09 | 45.00% (60) | two-component transcriptional regulatory protein |
| M. avium 104 | MAV_4201 | - | 0.0 | 72.80% (511) | transcriptional regulator, LuxR family protein |
| M. smegmatis MC2 155 | MSMEG_0856 | - | 2e-12 | 41.44% (111) | DNA-binding response regulator, LuxR family protein |
| M. thermoresistible (build 8) | TH_3563 | - | 2e-10 | 42.25% (71) | PUTATIVE DNA-binding response regulator, LuxR family protein |
| M. ulcerans Agy99 | MUL_3814 | - | 2e-09 | 45.00% (60) | two component transcriptional regulatory protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3959|M.marinum_M --------------------------------------------------
MUL_3814|M.ulcerans_Agy99 --------------------------------------------------
TH_3563|M.thermoresistible__bu --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2515c|M.bovis_AF2122/97 MDRRPRDFEQSRRRCRCNALRAGSMLASMSKIHPGVDVVPVDWSADGVSE
Rv2488c|M.tuberculosis_H37Rv MDRRPRDFEQSRRRCRCNALRAGSMLASMSKIHPGVDVVPVDWSADGVSE
MLBr_01753|M.leprae_Br4923 ----------------MYSLGEMQKPVPVGADYLASCLVARLRSTDVPTD
MSMEG_0856|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_2058|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4288|M.gilvum_PYR-GCK --------------------------------------------------
MAV_4201|M.avium_104 --------------------------------------------------
MMAR_3959|M.marinum_M --------------------------------------------------
MUL_3814|M.ulcerans_Agy99 --------------------------------------------------
TH_3563|M.thermoresistible__bu --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2515c|M.bovis_AF2122/97 LVPTGTVTLLLADIEGATHLPGSQLD--TTAIAKLDRTLTELVREHRGVC
Rv2488c|M.tuberculosis_H37Rv LVPTGTVTLLLADIEGATHLPGSQLD--TTAIAKLDRTLTELVREHRGVC
MLBr_01753|M.leprae_Br4923 LHRGCTVTLFLGDVEGLAELSETQPDEAADAIARLDCVVSEAVAAHGGVQ
MSMEG_0856|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_2058|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4288|M.gilvum_PYR-GCK --------------------------------------------------
MAV_4201|M.avium_104 --------------------------------------------------
MMAR_3959|M.marinum_M --------------------------------------------------
MUL_3814|M.ulcerans_Agy99 --------------------------------------------------
TH_3563|M.thermoresistible__bu --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2515c|M.bovis_AF2122/97 PVEQGEGDSFLVAFARASDAVACALGLQRAPLAPIRLRIGMHTGEVSSP-
Rv2488c|M.tuberculosis_H37Rv PVEQGEGDSFLVAFARASDAVACALGLQRAPLAPIRLRIGMHTGEVSSP-
MLBr_01753|M.leprae_Br4923 QVVQGVRGNFLATFARASDATACALDLQLAPIVPVRFRIALHTGEVQISN
MSMEG_0856|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_2058|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4288|M.gilvum_PYR-GCK --------------------------------------------------
MAV_4201|M.avium_104 --------------------------------------------------
MMAR_3959|M.marinum_M --------------------------------------------------
MUL_3814|M.ulcerans_Agy99 --------------------------------------------------
TH_3563|M.thermoresistible__bu --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2515c|M.bovis_AF2122/97 DEGNCVGPTIDRTARLRELAHGGQTVLSGTTSDLVADLLPKDAWLNDLGT
Rv2488c|M.tuberculosis_H37Rv DEGNCVGPTIDRTARLRELAHGGQTVLSGTTSDLVADLLPKDAWLNDLGT
MLBr_01753|M.leprae_Br4923 DDVNNVVFMMVQAAGLLDLACGGQTVLSSITGDLVVDGLPADTWLVDLGS
MSMEG_0856|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_2058|M.vanbaalenii_PYR-1 ---------------------------MAPPAEHPARSPSRAELLAALSI
Mflv_4288|M.gilvum_PYR-GCK ---------------------------MAPPAQPPVRTPSRAELLAALSI
MAV_4201|M.avium_104 ---------------------------MMLMAQ--AVLPTRAELLAALSV
MMAR_3959|M.marinum_M --------------------------------------------------
MUL_3814|M.ulcerans_Agy99 --------------------------------------------------
TH_3563|M.thermoresistible__bu --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2515c|M.bovis_AF2122/97 YRLDDLPRPERVVQLCHPDLHNAFPPLRTRKVVGAHCLPAQLTRLVGRVD
Rv2488c|M.tuberculosis_H37Rv YRLDDLPRPERVVQLCHPDLHNAFPPLRTRKVVGAHCLPAQLTRLVGRVD
MLBr_01753|M.leprae_Br4923 HLLRDLARPVRVMQLCHRNLRRNLHELGIRTVPGGPSLPVPLTTFVGRAA
MSMEG_0856|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_2058|M.vanbaalenii_PYR-1 AIDLGLGQPAEHMLRSAVIATRIAERLGLDRPQRDCCYYTALIMWIGCHA
Mflv_4288|M.gilvum_PYR-GCK AIDLGLGQPAEHMLRSAVIATRIADRLGLDRAERDCTYYTALIMWIGCHA
MAV_4201|M.avium_104 AIDLGLGQPAEHMLRAALIATRLCDRLGLSRQQRDCVYYTTLVMWVGCHA
MMAR_3959|M.marinum_M --------------------------------------------------
MUL_3814|M.ulcerans_Agy99 --------------------------------------------------
TH_3563|M.thermoresistible__bu --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2515c|M.bovis_AF2122/97 EVAQVRGLLDVKRWVTLTGVGGVGKTRLATQVASAVADGYPDGVWYVNLA
Rv2488c|M.tuberculosis_H37Rv EVAQVRGLLDVKRWVTLTGVGGVGKTRLATQVASAVADGYPDGVWYVNLA
MLBr_01753|M.leprae_Br4923 QIKELQELLTEKRLLTLVGPGGVGKTRLALQVVARVADEFSGELSYFDLA
MSMEG_0856|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_2058|M.vanbaalenii_PYR-1 DSHEYAHWFGDDIAVRHDSYLVDWTGLPYLRFLMANTG------------
Mflv_4288|M.gilvum_PYR-GCK DSHEYARWFGDDIAVRRDSYLVDWSGLPYLRFLMANTG------------
MAV_4201|M.avium_104 DSHEYARWFGDDIAVRHDSYLVDWSGIPYLRFLASNVG------------
MMAR_3959|M.marinum_M --------------------------------------------------
MUL_3814|M.ulcerans_Agy99 --------------------------------------------------
TH_3563|M.thermoresistible__bu --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2515c|M.bovis_AF2122/97 PITDPALVPIAAARVLGLPDQPGRSTVDTIVRRIGDRRMLVVLDNCEHLL
Rv2488c|M.tuberculosis_H37Rv PITDPALVPIAAARVLGLPDQPGRSTVDTIVRRIGDRRMLVVLDNCEHLL
MLBr_01753|M.leprae_Br4923 PDTDHDIFPIT--------------VLDNLRRCIGDRRMLMVLDNCEYLL
MSMEG_0856|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_2058|M.vanbaalenii_PYR-1 ----------------------------------RGQPLLHRLSLMATLL
Mflv_4288|M.gilvum_PYR-GCK ----------------------------------RGQPVLRRLSVLATLL
MAV_4201|M.avium_104 ----------------------------------RGQPLAHRLSVMATLF
MMAR_3959|M.marinum_M --------------------------------------------------
MUL_3814|M.ulcerans_Agy99 --------------------------------------------------
TH_3563|M.thermoresistible__bu --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2515c|M.bovis_AF2122/97 DGCAALIVALLGACPALRVLATSREPIAVAGEQIWRVPPLG-HGEAIELF
Rv2488c|M.tuberculosis_H37Rv DGCAALIVALLGACPALRVLATSREPIAVAGEQIWRVPPLG-HGEAIELF
MLBr_01753|M.leprae_Br4923 DVCANVMTTLLGACPSLTILATSREPIGVAGEVIWRVSMLSPADEAVELF
MSMEG_0856|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_2058|M.vanbaalenii_PYR-1 ADARGQISQLIHSHCASAGMLADRLGVSAEVQSALGSTFERYDGGGLPGG
Mflv_4288|M.gilvum_PYR-GCK ADARGQIAELIHSHCSSAGILADRLGLSADVQTVLGYTFERFDGGGLPGG
MAV_4201|M.avium_104 ANARGHISRLIHSHCASAALLADRIGLGPNVQAALAYTFERYDGGGLPTG
MMAR_3959|M.marinum_M --------------------------------------------------
MUL_3814|M.ulcerans_Agy99 --------------------------------------------------
TH_3563|M.thermoresistible__bu --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2515c|M.bovis_AF2122/97 TDRAREARPELEITADNLALVTEICHRLDGIPLAIELAASRVRALALTEI
Rv2488c|M.tuberculosis_H37Rv TDRAREARPELEITADNLALVTEICHRLDGIPLAIELAASRVRALALTEI
MLBr_01753|M.leprae_Br4923 TERAALVQPGFSVTDGNRQIVTEICQRLDGMPLAIELAAARIRTLSLTEI
MSMEG_0856|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_2058|M.vanbaalenii_PYR-1 VGGDDIP---LPMRVAQLADMVEVHHRAYGVDGAVAMARSRRGGQFDPRV
Mflv_4288|M.gilvum_PYR-GCK VGGDAIP---IPMRVAQLADTAEVHHRTFGVDGAVAMARSRSGGQFDPRV
MAV_4201|M.avium_104 ARGEDIP---IQMRIAQLADMVEVHHRSYGVAGAVAMVGARRGGQFDPGI
MMAR_3959|M.marinum_M --------------------------------------------------
MUL_3814|M.ulcerans_Agy99 --------------------------------------------------
TH_3563|M.thermoresistible__bu --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2515c|M.bovis_AF2122/97 VDSLHDRFRLLTGGSRIAVRRQQTMRASVDWSHALLTGPEQVLFRRLAVF
Rv2488c|M.tuberculosis_H37Rv VDSLHDRFRLLTGGSRIAVRRQQTMRASVDWSHALLTGPEQVLFRRLAVF
MLBr_01753|M.leprae_Br4923 ADGLDDRFRLLTGGARTAVRRQQTLRASMDWSYALLTESERALFRRLSAI
MSMEG_0856|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_2058|M.vanbaalenii_PYR-1 VDAFTADAVTVLSVPAPGDAWTVALREAPDYGERLHGAELDALLVALG--
Mflv_4288|M.gilvum_PYR-GCK VDAFLADADAILEPPE--DAWSAALREAPDYGTGLADGELDELLVALG--
MAV_4201|M.avium_104 ADVFLRDADAILAGPQTGDAWAAALREAPDR-HRVDEQSLDAALVALG--
MMAR_3959|M.marinum_M -------------------MSEHESPTVMVVDDHPIWRDA----------
MUL_3814|M.ulcerans_Agy99 -------------------MSEHESPTVMVVDDHPIWRDA----------
TH_3563|M.thermoresistible__bu -------------------MGEPQQPTVMVVDDHPIWREA----------
MAB_1522|M.abscessus_ATCC_1997 -------------------MTDTEVG-VLLVDDQELVRTG----------
Mb2515c|M.bovis_AF2122/97 PSGFDLDGAQAAAAGGDVQRYEVVDLLSLLADKSLVVTDDSDGRTRYRLL
Rv2488c|M.tuberculosis_H37Rv PSGFDLDGAQAAAAGGDVQRYEVVDLLSLLADKSLVVTDDSDGRTRYRLL
MLBr_01753|M.leprae_Br4923 SGTFDLKVAYAVGHDDLEEPDQVFDRLTMLIDKSLVIVEGRQGGSRYRLL
MSMEG_0856|M.smegmatis_MC2_155 -----------------------MAARILLADDHALVRSG----------
Mvan_2058|M.vanbaalenii_PYR-1 -DFVDLKCPFTLGHSRAVAELAAGAAAVVGLDADTVTVVRRAG-------
Mflv_4288|M.gilvum_PYR-GCK -DFVDLKCPFTLGHSRAVAELAAGAAALMGMDAGGVDLLRRAG-------
MAV_4201|M.avium_104 -DFVDLKCPFTLGHSRAVARLAGQAARAAGLDADAVALTRRAG-------
* :
MMAR_3959|M.marinum_M -------VARDLS-DDGFAVVATADGVATAQRR-----------------
MUL_3814|M.ulcerans_Agy99 -------VARDLS-DDGFAVVATADGVATAQRR-----------------
TH_3563|M.thermoresistible__bu -------VARDLA-EAGLSVVATADGVAAARRR-----------------
MAB_1522|M.abscessus_ATCC_1997 -------LRRILRRKDGFAIVGECADGSEVAAA-----------------
Mb2515c|M.bovis_AF2122/97 ETVRQYALEKLRESGDADAVRARHRDHYAAVAAGLDAPSVAGHERRLNQA
Rv2488c|M.tuberculosis_H37Rv ETVRQYALEKLRESGDADAVRARHRDHYAAVAAGLDAPSVAGHERRLNQA
MLBr_01753|M.leprae_Br4923 ETVRQYAMKKLEESNEVDLVLARHRDHYMALGALLDTPGDIDHEQLVEQV
MSMEG_0856|M.smegmatis_MC2_155 -------LRMIIDAEPDLQVVAEAADGYEALSA-----------------
Mvan_2058|M.vanbaalenii_PYR-1 ------HLHDLGRIGVSNQIWSKPSSLTARELER----------------
Mflv_4288|M.gilvum_PYR-GCK ------HVHDVGRIGVSNQVWSKPSTLTTGEMER----------------
MAV_4201|M.avium_104 ------HVHDLGRIGVSNQIWSRPGPLSGSQFER----------------
: : .
MMAR_3959|M.marinum_M --------------------------------------------------
MUL_3814|M.ulcerans_Agy99 --------------------------------------------------
TH_3563|M.thermoresistible__bu --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2515c|M.bovis_AF2122/97 ELEIDNLRAAFAFSRENGDTGHALLLASCLQPLWRARGRLQEGLAWFAAA
Rv2488c|M.tuberculosis_H37Rv ELEIDNLRAAFAFSRENGDTGHALLLASCLQPLWRARGRLQEGLAWFAAA
MLBr_01753|M.leprae_Br4923 ETELDNLRSAFAWSRETGDIAGALQLASSLQPIWFGRGHMYEGLAWFDSI
MSMEG_0856|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_2058|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4288|M.gilvum_PYR-GCK --------------------------------------------------
MAV_4201|M.avium_104 --------------------------------------------------
MMAR_3959|M.marinum_M ---------------AAIVKPDVVVMDMRLA--------DGDGVQATTEV
MUL_3814|M.ulcerans_Agy99 ---------------AAIVKPDVVVMDMRLA--------DGDGVQATTEV
TH_3563|M.thermoresistible__bu ---------------AAAVRPDVVLMDMRLP--------DGDGARATAEV
MAB_1522|M.abscessus_ATCC_1997 ---------------VSRARPDVVIMDLRMK--------QMSGIEAIRLL
Mb2515c|M.bovis_AF2122/97 LADHDAHPAGADPGLYARALADRALIDAVAG-----ITDRLDDAQKALAI
Rv2488c|M.tuberculosis_H37Rv LADHDAHPAGADPGLYARALADRALIDAVAG-----ITDRLDDAQKALAI
MLBr_01753|M.leprae_Br4923 FEHKNIEHLVAPKEVLARAVANKVMLHAILASSPPDGSDLVTQAQQALTM
MSMEG_0856|M.smegmatis_MC2_155 ---------------LDTETVDLAILDIAMP--------RMTGLQAAREI
Mvan_2058|M.vanbaalenii_PYR-1 --------------VRLHPYLTVRILSQVGG---------LDAVAQVAGN
Mflv_4288|M.gilvum_PYR-GCK --------------VRLHPYLTVRILSQVGG---------LDAVARVAGN
MAV_4201|M.avium_104 --------------VRLHPYLTVRILDQVPG---------LRRLAEVAGN
::
MMAR_3959|M.marinum_M LKVSPATRVLVLSASDE-----------REDVLEAVKAG-----------
MUL_3814|M.ulcerans_Agy99 LKVSPATRVLVLSTSDE-----------REDVLEAVKTG-----------
TH_3563|M.thermoresistible__bu RAVSPDSRVLVLSASEE-----------RDDVLEAVKAG-----------
MAB_1522|M.abscessus_ATCC_1997 HAAQ-GPPALALTTFDD-----------DELLSGALRAG-----------
Mb2515c|M.bovis_AF2122/97 ARDIEDPALLARALTACGGVAAYNADLARPWLAEAVGLARAVGDKWRLAE
Rv2488c|M.tuberculosis_H37Rv ARDIEDPALLARALTACGGVAAYNADLARPWLAEAVGLARAVGDKWRLAE
MLBr_01753|M.leprae_Br4923 AREIGDSAVLARALTACGFSSGYDTEVARPYFAEAVELARTQGDKWTLSQ
MSMEG_0856|M.smegmatis_MC2_155 NRSHPDVRILILSMYDN-----------EQYFFEALKAG-----------
Mvan_2058|M.vanbaalenii_PYR-1 HHEYLDGSGYPRGLPAAALS------LPDRLLAAAVAYQ-----------
Mflv_4288|M.gilvum_PYR-GCK HHECLDGSGYPRGLPAAALS------VPDRVLAAAVAYR-----------
MAV_4201|M.avium_104 HHECLDGSGYPRGLAGSALG------MPDRILAAAVCYQ-----------
. *:
MMAR_3959|M.marinum_M --------------------------------------------------
MUL_3814|M.ulcerans_Agy99 --------------------------------------------------
TH_3563|M.thermoresistible__bu --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2515c|M.bovis_AF2122/97 VLAWQAYVGFAGEGDPGATRAAGEEARSLADEIGDAFLSRSCRWALAAAN
Rv2488c|M.tuberculosis_H37Rv VLAWQAYVGFAGEGDPGATRAAGEEARSLADEIGDAFLSRSCRWALAAAN
MLBr_01753|M.leprae_Br4923 IRLWG-VVGFCVSGDPVALRAAAEAADDLAQEIGDRFVSLQCRLLLSIAQ
MSMEG_0856|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_2058|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4288|M.gilvum_PYR-GCK --------------------------------------------------
MAV_4201|M.avium_104 --------------------------------------------------
MMAR_3959|M.marinum_M --------------------------------------------------
MUL_3814|M.ulcerans_Agy99 --------------------------------------------------
TH_3563|M.thermoresistible__bu --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2515c|M.bovis_AF2122/97 LWQGNLEAAVGLSREVIGESDAAHDMVSSCAGQACLAHALAHRGDTEAAA
Rv2488c|M.tuberculosis_H37Rv LWQGNLEAAVGLSREVIGESDAAHDMVSSCAGQACLAHALAHRGDTEAAA
MLBr_01753|M.leprae_Br4923 LWQGDMDGAIVRSGEVVAGAEAAHDTVTRTFGLYVQTRALVHRDVSAALV
MSMEG_0856|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_2058|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4288|M.gilvum_PYR-GCK --------------------------------------------------
MAV_4201|M.avium_104 --------------------------------------------------
MMAR_3959|M.marinum_M --------------------ATGYLVKSASKAELADAVRATAAGRAVFTP
MUL_3814|M.ulcerans_Agy99 --------------------ATGYLVKSASKAELADAVRATAAGRAVFTP
TH_3563|M.thermoresistible__bu --------------------ATGYLVKSASKTELVDAVHATAQGRAVFTP
MAB_1522|M.abscessus_ATCC_1997 --------------------AAGFILKDSPAEELVRAVHAVARGEAYLDP
Mb2515c|M.bovis_AF2122/97 AAQASIDTAVGLSPVLSGSACSALVFATLAAGDVAAAEHARESATRFFGA
Rv2488c|M.tuberculosis_H37Rv AAQASIDTAVGLSPVLSGSACSALVFATLAAGDVAAAEHARESATRFFGA
MLBr_01753|M.leprae_Br4923 TAGLVVEAAAELSGVYQGIGYAAMVFAALAMGDVAAAVEASEACRPHLGA
MSMEG_0856|M.smegmatis_MC2_155 --------------------ASGYVLKSVADRDLLEACRATLRGEPFLYA
Mvan_2058|M.vanbaalenii_PYR-1 ------------------SALEPRPYRDPLPATSAAARLRERVREGRLDE
Mflv_4288|M.gilvum_PYR-GCK ------------------SAVEPRPYRVALSPAAAATRLRDRVREGHLDE
MAV_4201|M.avium_104 ------------------SGREPRPYREQLSEAEAARRLRGRVRCGELDP
:
MMAR_3959|M.marinum_M SLAGLVLG------------------------------------------
MUL_3814|M.ulcerans_Agy99 SLAGLVLG------------------------------------------
TH_3563|M.thermoresistible__bu GLAGLVLG------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 AVTSRVLN------------------------------------------
Mb2515c|M.bovis_AF2122/97 SAAAIINDPTSSAQISCARGDLNAAHRLADGAASITRGVHRARALTTRCR
Rv2488c|M.tuberculosis_H37Rv SAAAIINDPTSSAQISCARGDLNAAHRLADGAASITRGVHRARALTTRCR
MLBr_01753|M.leprae_Br4923 DHGLVAIHLELMAAVALARGDVIVARRLADNSVSATTGWHQMAALTTRAR
MSMEG_0856|M.smegmatis_MC2_155 GAITALIR------------------------------------------
Mvan_2058|M.vanbaalenii_PYR-1 VAVEAVLQ------------------------------------------
Mflv_4288|M.gilvum_PYR-GCK LAVDAVLS------------------------------------------
MAV_4201|M.avium_104 VAAEAVLH------------------------------------------
MMAR_3959|M.marinum_M --------------------------------------------------
MUL_3814|M.ulcerans_Agy99 --------------------------------------------------
TH_3563|M.thermoresistible__bu --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2515c|M.bovis_AF2122/97 IEIAQGDRHRAERDAHDALGVAASIGAYLWVPDILECLASVMADAGSNRE
Rv2488c|M.tuberculosis_H37Rv IEIAQGDRHRAERDAHDALGVAASIGAYLWVPDILECLASVMADAGSNRE
MLBr_01753|M.leprae_Br4923 IAMAQGEPELARADIHAALACGADIQASLGISDSMELLAELISQGDNHRQ
MSMEG_0856|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_2058|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4288|M.gilvum_PYR-GCK --------------------------------------------------
MAV_4201|M.avium_104 --------------------------------------------------
MMAR_3959|M.marinum_M --------------------------------------------------
MUL_3814|M.ulcerans_Agy99 --------------------------------------------------
TH_3563|M.thermoresistible__bu --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2515c|M.bovis_AF2122/97 AVRLFGAADAARGRMGAVRFGIYQAGCNSSLATLRKSMGDSEFDDAWAEG
Rv2488c|M.tuberculosis_H37Rv AVRLFGAADAARGRMGAVRFGIYQAGCNSSLATLRKSMGDSEFDDAWAEG
MLBr_01753|M.leprae_Br4923 AGRLFGAASAQREKTGEVRFKVWDAGYESAVAVLRGAMGCKDFDSAWAEG
MSMEG_0856|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_2058|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4288|M.gilvum_PYR-GCK --------------------------------------------------
MAV_4201|M.avium_104 --------------------------------------------------
MMAR_3959|M.marinum_M -----------EYRRIAQTADSSQDRPSLTERETEILRYVAKGLSAKQIA
MUL_3814|M.ulcerans_Agy99 -----------EYRRIAQTADSSQDRPSLTERETEILRYVAKGLSAKQIA
TH_3563|M.thermoresistible__bu -----------EYRRISRQPGAGPDAPRLTERETEILRYVAKGLTAKQIA
MAB_1522|M.abscessus_ATCC_1997 -----------AYRRAP-AAVSGDAQDKLTARELDVLALIASGATNSEIA
Mb2515c|M.bovis_AF2122/97 TALSIDEAIAYAQRGRGARKRPTSGWGALTPTELEVALLVGEGLSNKEIG
Rv2488c|M.tuberculosis_H37Rv TALSIDEAIAYAQRGRGARKRPTSGWGALTPTELEVALLVGEGLSNKEIG
MLBr_01753|M.leprae_Br4923 AAMPIDDAITYAQRGRGNRKRPTTGWESLTPAEHNVIRLVSEGLDTKDIA
MSMEG_0856|M.smegmatis_MC2_155 ---------DFLHRARQGGEPPDS---ILTPREEEVLKLIAEGYSTREIA
Mvan_2058|M.vanbaalenii_PYR-1 ------------AAGHRAR-GHSPRPGGLTPREIEVLCLVARGASNKEIA
Mflv_4288|M.gilvum_PYR-GCK ------------AAGHAAR-RVSARPGGLTPREIEVLCLVARGASNKEIA
MAV_4201|M.avium_104 ------------AAGQPVGPRPNPRPDGLTPREIEVLGHVARGASNKEIA
** * :: :. * :*.
MMAR_3959|M.marinum_M EKLSLSHRTVENHVQATFRKLQVANRVELTRYAIEHGLDK------
MUL_3814|M.ulcerans_Agy99 EKLSLSHRTVENHVQATFRKLQLANRVELTRYAIEHGLDK------
TH_3563|M.thermoresistible__bu AQLSLSHRTVENHVQATFRKLQVANRVELARYAIEHGLDE------
MAB_1522|M.abscessus_ATCC_1997 EQLVISEVTVKSHIGRIFVKLDLRDRAAAIVYAYDHGIVTPK----
Mb2515c|M.bovis_AF2122/97 VRLFISPRTVHSHLTHVYTKLGLSSRLQLAQQAARRGESERGPSRP
Rv2488c|M.tuberculosis_H37Rv VRLFISPRTVHSHLTHVYTKLGLSSRLQLAQQAARRGESERGPSRP
MLBr_01753|M.leprae_Br4923 ARLFVSVRTVHTHLTRIYSKLGLTSRVQLVQEAARHN---------
MSMEG_0856|M.smegmatis_MC2_155 ATLTISAKTVDRHRTNILAKLGLRDRLALTRYAIRAGLIEP-----
Mvan_2058|M.vanbaalenii_PYR-1 ATLGISGKTARNHVERTYAKIGATNRIGASMFALNHGLVAPA----
Mflv_4288|M.gilvum_PYR-GCK ATLGISGKTARNHVERTYAKIGATNRIGASMFALGHGLITPA----
MAV_4201|M.avium_104 AALVISEKTARNHVERTYAKIGVSNRIGASMYALQHGLVPAAPPHS
* :* *. * *: .* * .