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MAARILLADDHALVRSGLRMIIDAEPDLQVVAEAADGYEALSALDTETVDLAILDIAMPRMTGLQAAREI NRSHPDVRILILSMYDNEQYFFEALKAGASGYVLKSVADRDLLEACRATLRGEPFLYAGAITALIRDFLH RARQGGEPPDSILTPREEEVLKLIAEGYSTREIAATLTISAKTVDRHRTNILAKLGLRDRLALTRYAIRA GLIEP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0856 | - | - | 100% (215) | DNA-binding response regulator, LuxR family protein |
| M. smegmatis MC2 155 | MSMEG_1494 | - | 7e-30 | 35.00% (220) | transcriptional regulatory protein DegU |
| M. smegmatis MC2 155 | MSMEG_5244 | - | 6e-29 | 33.33% (204) | two component transcriptional regulatory protein devr |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3157c | devR | 3e-29 | 33.82% (204) | two component transcriptional regulatory protein DevR |
| M. gilvum PYR-GCK | Mflv_5014 | - | 2e-31 | 36.11% (216) | two component LuxR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3133c | devR | 3e-29 | 33.82% (204) | two component transcriptional regulatory protein DevR |
| M. leprae Br4923 | MLBr_01286 | - | 7e-13 | 36.61% (112) | putative two-component response regulatory protein |
| M. abscessus ATCC 19977 | MAB_1522 | - | 2e-30 | 38.03% (213) | putative two-component system response regulator LuxR |
| M. marinum M | MMAR_3480 | - | 1e-29 | 33.17% (208) | two-component transcriptional regulatory protein |
| M. avium 104 | MAV_5280 | - | 1e-31 | 37.44% (211) | two-component system response regulator |
| M. thermoresistible (build 8) | TH_2159 | - | 6e-30 | 34.85% (198) | TWO COMPONENT TRANSCRIPTIONAL REGULATORY PROTEIN DEVR (PROBABLY |
| M. ulcerans Agy99 | MUL_2423 | devR | 2e-29 | 34.63% (205) | two component transcriptional regulatory protein DevR |
| M. vanbaalenii PYR-1 | Mvan_1646 | - | 1e-95 | 82.63% (213) | two component LuxR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_0856|M.smegmatis_MC2_155 -----------MAARILLADDHALVRSGLRMIIDAEPD-LQVVAEAADGY
Mvan_1646|M.vanbaalenii_PYR-1 -------MTPPPVARILLADDHALVRSGLRMILDAEPD-LRVVVEAADGY
Mflv_5014|M.gilvum_PYR-GCK --------MSSEPVRIVLVDDHEMVIEGLKAMLAAFADRVCVVGQSVGAD
Mb3157c|M.bovis_AF2122/97 ------------MVKVFLVDDHEVVRRGLVDLLGADPE-LDVVGEAGSVA
Rv3133c|M.tuberculosis_H37Rv ------------MVKVFLVDDHEVVRRGLVDLLGADPE-LDVVGEAGSVA
MUL_2423|M.ulcerans_Agy99 ------------MVTVFLVDDHEVVRRGLIDLLDADPQ-LDVVGEAGSVS
MMAR_3480|M.marinum_M ------------MVKVFLVDDHEVVRRGLVDLLGSDPD-LEIIGEAGSVS
TH_2159|M.thermoresistible__bu ------------MVSVFLVDDHEVVRRGLIDLLDSDPD-LEVVGEAGTVA
MAB_1522|M.abscessus_ATCC_1997 ------MTD--TEVGVLLVDDQELVRTGLRRILRRKDG-FAIVGECADGS
MAV_5280|M.avium_104 ------MTDPAPEITVLLVDDQDLVRSGLRRILRRKDG-FVIVAECADGD
MLBr_01286|M.leprae_Br4923 MTGPTTDADAATPHRVLIAEDEALIRLDLAEMLR-DEG-YDIVGEAADGQ
:.:.:*. :: .* :: :: :.
MSMEG_0856|M.smegmatis_MC2_155 EALSALDTETVDLAILDIAMPRMTGLQAAREINRSHPDVRILILSMYDNE
Mvan_1646|M.vanbaalenii_PYR-1 QALNALEQTPVDIAILDIAMPRMTGLQAAREISRKYPHVRILILSMHDNE
Mflv_5014|M.gilvum_PYR-GCK QVMGVVTDLDPDIVLCDVRMQGSSGLDVCQQLRRRDPDRKIVMLSVYDDE
Mb3157c|M.bovis_AF2122/97 EAMARVPAARPDVAVLDVRLPDGNGIELCRDLLSRMPDLRCLILTSYTSD
Rv3133c|M.tuberculosis_H37Rv EAMARVPAARPDVAVLDVRLPDGNGIELCRDLLSRMPDLRCLILTSYTSD
MUL_2423|M.ulcerans_Agy99 EAMARIPAANPDVAVLDVRLPDGDGIELCRDLLSRMPNLRCLILTSYTSD
MMAR_3480|M.marinum_M EAMARIPALQPDVAVLDVRLPDGNGIELCRDLLSDLPELRCLMLTSFTSD
TH_2159|M.thermoresistible__bu QAMARIPAAQPDVAVLDVRLPDGNGVELCRDLLARMPDLRCLMLTSYTSD
MAB_1522|M.abscessus_ATCC_1997 EVAAAVSRARPDVVIMDLRMKQMSGIEAIRLLHAAQ-GPPALALTTFDDD
MAV_5280|M.avium_104 EVPAAVAAHRPDVVVMDLRMRRVDGIEATRRLGGR---PPVLALTTFNED
MLBr_01286|M.leprae_Br4923 EAVELAERHKPDLVIMDVKMPRRDGIDAASEIASKR-IAPIVVLTAFSQR
:. *:.: *: : *:: : : *: . .
MSMEG_0856|M.smegmatis_MC2_155 QYFFEALKAGASGYVLKSVADRDLLEACRATLRGEPFLYAGAITALIRDF
Mvan_1646|M.vanbaalenii_PYR-1 QYFFEALRAGASGYVLKSVADLDLLKACRATLRGEPFVYPGAVTALIQDY
Mflv_5014|M.gilvum_PYR-GCK QYLFQAMRVGASGYLLKSISSEDLVEQLESVHSGKTAIDP-TMAARAVEW
Mb3157c|M.bovis_AF2122/97 EAMLDAILAGASGYVVKDIKGMELARAVKDVGAGRSLLDNRAAAALMAKL
Rv3133c|M.tuberculosis_H37Rv EAMLDAILAGASGYVVKDIKGMELARAVKDVGAGRSLLDNRAAAALMAKL
MUL_2423|M.ulcerans_Agy99 EAMLDAILAGASGYVVKDIKGMELARAIKEVGAGRSLLDNRAAAALMSRL
MMAR_3480|M.marinum_M EAMLEAILAGASGYVVKDIKGMELARAIKDVGAGKSLLDNRAAAALMAKL
TH_2159|M.thermoresistible__bu QAMLDAILAGASGYVVKDIKGMELAQAIKDVGAGRSLLDNRAAEALMAKL
MAB_1522|M.abscessus_ATCC_1997 ELLSGALRAGAAGFILKDSPAEELVRAVHAVARGEAYLDPAVTSRVLNAY
MAV_5280|M.avium_104 ELLSGALRAGAAGFVLKDSSAEELIRAVRAVARGEGYLDPAVTSRVLTTY
MLBr_01286|M.leprae_Br4923 DLVERARDAGAMAYLVKPFTISDLIPAIALAMSRFSELTALEREVATLAD
: . * .** .:::* :* . :
MSMEG_0856|M.smegmatis_MC2_155 LHRARQGGEPPDSILTPREEEVLKLIAEGYSTREIAATLTISAKTVDRHR
Mvan_1646|M.vanbaalenii_PYR-1 LNRARHGDDLPGTIVTSREEEVLKLIAEGYSTREIAGTLGISAKTVDRHR
Mflv_5014|M.gilvum_PYR-GCK PG-ARQG-------LTQRESEILALVVNGLSNRAIAAKLIIGDETVKTHL
Mb3157c|M.bovis_AF2122/97 RGAAEKQDPLSG--LTDQERTLLGLLSEGLTNKQIADRMFLAEKTVKNYV
Rv3133c|M.tuberculosis_H37Rv RGAAEKQDPLSG--LTDQERTLLGLLSEGLTNKQIADRMFLAEKTVKNYV
MUL_2423|M.ulcerans_Agy99 RGVVERPDPLSG--LTDQERTLLGLLSEGLTNKQIADRMFLAEKTVKNYV
MMAR_3480|M.marinum_M RGGAEQKDPLSG--LTEQERTLLGHLSEGLTNRQIAARMFLAEKTVKNYV
TH_2159|M.thermoresistible__bu RGADHQPDPLAG--LSDQERVLLSLIGEGLTNKQIAARMFLAEKTVKNYV
MAB_1522|M.abscessus_ATCC_1997 RRAPAAVSGDAQDKLTARELDVLALIASGATNSEIAEQLVISEVTVKSHI
MAV_5280|M.avium_104 RKAAPGPHGAAIAELTTRERDVLTLIGKGLSNSEIADELCISGVTVKSHI
MLBr_01286|M.leprae_Br4923 RLETRKLVERAKGLLQVKQG-----MTEPEAFKWIQRAAMDRRTTMKRVA
: :: : . : * *:.
MSMEG_0856|M.smegmatis_MC2_155 TNILAKLGLRDRLALTRYAIRAGLIEP-----
Mvan_1646|M.vanbaalenii_PYR-1 ANLLAKLGLRDRLALTRYAIRVGLIEP-----
Mflv_5014|M.gilvum_PYR-GCK SSIYRKLGVSDRTAAVATALREGIFQ------
Mb3157c|M.bovis_AF2122/97 SRLLAKLGMERRTQAAVFATELKRSRPPGDGP
Rv3133c|M.tuberculosis_H37Rv SRLLAKLGMERRTQAAVFATELKRSRPPGDGP
MUL_2423|M.ulcerans_Agy99 SRLLAKLGMERRTQAAVFAAELKRARSAGHR-
MMAR_3480|M.marinum_M SRLLAKLGMERRTQAAVFASRLGQGTRPVQGD
TH_2159|M.thermoresistible__bu SRLLAKLGMERRTQAAVFVSKLDRPIDPRG--
MAB_1522|M.abscessus_ATCC_1997 GRIFVKLDLRDRAAAIVYAYDHGIVTPK----
MAV_5280|M.avium_104 GRIFGKLDLRDRAAAIVYAYDNGIVAPR----
MLBr_01286|M.leprae_Br4923 EVVLETLDTPKDT-------------------
: .*.