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M. avium 104 MAV_4201 (-)

annotation: transcriptional regulator, LuxR family protein
coordinates: 4327982 - 4329553
length: 523

MLMAQAVLPTRAELLAALSVAIDLGLGQPAEHMLRAALIATRLCDRLGLSRQQRDCVYYTTLVMWVGCHA
DSHEYARWFGDDIAVRHDSYLVDWSGIPYLRFLASNVGRGQPLAHRLSVMATLFANARGHISRLIHSHCA
SAALLADRIGLGPNVQAALAYTFERYDGGGLPTGARGEDIPIQMRIAQLADMVEVHHRSYGVAGAVAMVG
ARRGGQFDPGIADVFLRDADAILAGPQTGDAWAAALREAPDRHRVDEQSLDAALVALGDFVDLKCPFTLG
HSRAVARLAGQAARAAGLDADAVALTRRAGHVHDLGRIGVSNQIWSRPGPLSGSQFERVRLHPYLTVRIL
DQVPGLRRLAEVAGNHHECLDGSGYPRGLAGSALGMPDRILAAAVCYQSGREPRPYREQLSEAEAARRLR
GRVRCGELDPVAAEAVLHAAGQPVGPRPNPRPDGLTPREIEVLGHVARGASNKEIAAALVISEKTARNHV
ERTYAKIGVSNRIGASMYALQHGLVPAAPPHS*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_4201--100% (523)transcriptional regulator, LuxR family protein
M. avium 104MAV_4114-2e-1147.69% (65) response regulator receiver domain-containing protein
M. avium 104MAV_0872-5e-1032.08% (106) DNA-binding response regulator, LuxR family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2515c-8e-0928.19% (188) LuxR family transcriptional regulator
M. gilvum PYR-GCKMflv_4288-0.071.23% (511) metal dependent phosphohydrolase
M. tuberculosis H37RvRv2488c-9e-0928.19% (188) LuxR family transcriptional regulator
M. leprae Br4923MLBr_01753-8e-0933.01% (103) putative transcriptional regulator
M. abscessus ATCC 19977MAB_1522-4e-1340.19% (107) putative two-component system response regulator LuxR
M. marinum MMMAR_3959-4e-1148.33% (60) two-component transcriptional regulatory protein
M. smegmatis MC2 155MSMEG_4339-2e-1530.30% (297) TPR repeat-containing protein
M. thermoresistible (build 8)TH_3563-3e-1243.84% (73) PUTATIVE DNA-binding response regulator, LuxR family protein
M. ulcerans Agy99MUL_3814-5e-1146.67% (60) two component transcriptional regulatory protein
M. vanbaalenii PYR-1Mvan_2058-0.072.80% (511) metal dependent phosphohydrolase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4288|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2058|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_4201|M.avium_104                --------------------------------------------------
MMAR_3959|M.marinum_M               --------------------------------------------------
MUL_3814|M.ulcerans_Agy99           --------------------------------------------------
TH_3563|M.thermoresistible__bu      --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997      --------------------------------------------------
Mb2515c|M.bovis_AF2122/97           MDRRPRDFEQSRRRCRCNALRAGSMLASMSKIHPGVDVVPVDWSADGVSE
Rv2488c|M.tuberculosis_H37Rv        MDRRPRDFEQSRRRCRCNALRAGSMLASMSKIHPGVDVVPVDWSADGVSE
MLBr_01753|M.leprae_Br4923          ----------------MYSLGEMQKPVPVGADYLASCLVARLRSTDVPTD
MSMEG_4339|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_4288|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2058|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_4201|M.avium_104                --------------------------------------------------
MMAR_3959|M.marinum_M               --------------------------------------------------
MUL_3814|M.ulcerans_Agy99           --------------------------------------------------
TH_3563|M.thermoresistible__bu      --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997      --------------------------------------------------
Mb2515c|M.bovis_AF2122/97           LVPTGTVTLLLADIEGATHLPGSQLD--TTAIAKLDRTLTELVREHRGVC
Rv2488c|M.tuberculosis_H37Rv        LVPTGTVTLLLADIEGATHLPGSQLD--TTAIAKLDRTLTELVREHRGVC
MLBr_01753|M.leprae_Br4923          LHRGCTVTLFLGDVEGLAELSETQPDEAADAIARLDCVVSEAVAAHGGVQ
MSMEG_4339|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_4288|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2058|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_4201|M.avium_104                --------------------------------------------------
MMAR_3959|M.marinum_M               --------------------------------------------------
MUL_3814|M.ulcerans_Agy99           --------------------------------------------------
TH_3563|M.thermoresistible__bu      --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997      --------------------------------------------------
Mb2515c|M.bovis_AF2122/97           PVEQGEGDSFLVAFARASDAVACALGLQRAPLAPIRLRIGMHTGEVSSP-
Rv2488c|M.tuberculosis_H37Rv        PVEQGEGDSFLVAFARASDAVACALGLQRAPLAPIRLRIGMHTGEVSSP-
MLBr_01753|M.leprae_Br4923          QVVQGVRGNFLATFARASDATACALDLQLAPIVPVRFRIALHTGEVQISN
MSMEG_4339|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_4288|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2058|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_4201|M.avium_104                --------------------------------------------------
MMAR_3959|M.marinum_M               --------------------------------------------------
MUL_3814|M.ulcerans_Agy99           --------------------------------------------------
TH_3563|M.thermoresistible__bu      --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997      --------------------------------------------------
Mb2515c|M.bovis_AF2122/97           DEGNCVGPTIDRTARLRELAHGGQTVLSGTTSDLVADLLPKDAWLNDLGT
Rv2488c|M.tuberculosis_H37Rv        DEGNCVGPTIDRTARLRELAHGGQTVLSGTTSDLVADLLPKDAWLNDLGT
MLBr_01753|M.leprae_Br4923          DDVNNVVFMMVQAAGLLDLACGGQTVLSSITGDLVVDGLPADTWLVDLGS
MSMEG_4339|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_4288|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2058|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_4201|M.avium_104                --------------------------------------------------
MMAR_3959|M.marinum_M               --------------------------------------------------
MUL_3814|M.ulcerans_Agy99           --------------------------------------------------
TH_3563|M.thermoresistible__bu      --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997      --------------------------------------------------
Mb2515c|M.bovis_AF2122/97           YRLDDLPRPERVVQLCHPDLHNAFPPLRTRKVVGAHCLPAQLTRLVGRVD
Rv2488c|M.tuberculosis_H37Rv        YRLDDLPRPERVVQLCHPDLHNAFPPLRTRKVVGAHCLPAQLTRLVGRVD
MLBr_01753|M.leprae_Br4923          HLLRDLARPVRVMQLCHRNLRRNLHELGIRTVPGGPSLPVPLTTFVGRAA
MSMEG_4339|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_4288|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2058|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_4201|M.avium_104                --------------------------------------------------
MMAR_3959|M.marinum_M               --------------------------------------------------
MUL_3814|M.ulcerans_Agy99           --------------------------------------------------
TH_3563|M.thermoresistible__bu      --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997      --------------------------------------------------
Mb2515c|M.bovis_AF2122/97           EVAQVRGLLDVKRWVTLTGVGGVGKTRLATQVASAVADGYPDGVWYVNLA
Rv2488c|M.tuberculosis_H37Rv        EVAQVRGLLDVKRWVTLTGVGGVGKTRLATQVASAVADGYPDGVWYVNLA
MLBr_01753|M.leprae_Br4923          QIKELQELLTEKRLLTLVGPGGVGKTRLALQVVARVADEFSGELSYFDLA
MSMEG_4339|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_4288|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2058|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_4201|M.avium_104                --------------------------------------------------
MMAR_3959|M.marinum_M               --------------------------------------------------
MUL_3814|M.ulcerans_Agy99           --------------------------------------------------
TH_3563|M.thermoresistible__bu      --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997      --------------------------------------------------
Mb2515c|M.bovis_AF2122/97           PITDPALVPIAAARVLGLPDQPGRSTVDTIVRRIGDRRMLVVLDNCEHLL
Rv2488c|M.tuberculosis_H37Rv        PITDPALVPIAAARVLGLPDQPGRSTVDTIVRRIGDRRMLVVLDNCEHLL
MLBr_01753|M.leprae_Br4923          PDTDHDIFPIT--------------VLDNLRRCIGDRRMLMVLDNCEYLL
MSMEG_4339|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_4288|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2058|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_4201|M.avium_104                --------------------------------------------------
MMAR_3959|M.marinum_M               --------------------------------------------------
MUL_3814|M.ulcerans_Agy99           --------------------------------------------------
TH_3563|M.thermoresistible__bu      --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997      --------------------------------------------------
Mb2515c|M.bovis_AF2122/97           DGCAALIVALLGACPALRVLATSREPIAVAGEQIWRVPPLG-HGEAIELF
Rv2488c|M.tuberculosis_H37Rv        DGCAALIVALLGACPALRVLATSREPIAVAGEQIWRVPPLG-HGEAIELF
MLBr_01753|M.leprae_Br4923          DVCANVMTTLLGACPSLTILATSREPIGVAGEVIWRVSMLSPADEAVELF
MSMEG_4339|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_4288|M.gilvum_PYR-GCK          ---------------------------------MAPPAQPPVRTPSRAEL
Mvan_2058|M.vanbaalenii_PYR-1       ---------------------------------MAPPAEHPARSPSRAEL
MAV_4201|M.avium_104                ---------------------------------MMLMAQ--AVLPTRAEL
MMAR_3959|M.marinum_M               --------------------------------------------------
MUL_3814|M.ulcerans_Agy99           --------------------------------------------------
TH_3563|M.thermoresistible__bu      --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997      --------------------------------------------------
Mb2515c|M.bovis_AF2122/97           TDRAREARPELEITADNLALVTEICHRLDGIPLAIELAASRVRALALTEI
Rv2488c|M.tuberculosis_H37Rv        TDRAREARPELEITADNLALVTEICHRLDGIPLAIELAASRVRALALTEI
MLBr_01753|M.leprae_Br4923          TERAALVQPGFSVTDGNRQIVTEICQRLDGMPLAIELAAARIRTLSLTEI
MSMEG_4339|M.smegmatis_MC2_155      ---------------------------------MTTATGSVGRASDHPAL
                                                                                      

Mflv_4288|M.gilvum_PYR-GCK          LAALSIAIDLGLGQPAEHMLRSAVIATRIADRLGLDRAERDCTYYTALIM
Mvan_2058|M.vanbaalenii_PYR-1       LAALSIAIDLGLGQPAEHMLRSAVIATRIAERLGLDRPQRDCCYYTALIM
MAV_4201|M.avium_104                LAALSVAIDLGLGQPAEHMLRAALIATRLCDRLGLSRQQRDCVYYTTLVM
MMAR_3959|M.marinum_M               --------------------------------------------------
MUL_3814|M.ulcerans_Agy99           --------------------------------------------------
TH_3563|M.thermoresistible__bu      --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997      --------------------------------------------------
Mb2515c|M.bovis_AF2122/97           VDSLHDRFRLLTGGSRIAVRRQQTMRASVDWSHALLTGPEQVLFRRLAVF
Rv2488c|M.tuberculosis_H37Rv        VDSLHDRFRLLTGGSRIAVRRQQTMRASVDWSHALLTGPEQVLFRRLAVF
MLBr_01753|M.leprae_Br4923          ADGLDDRFRLLTGGARTAVRRQQTLRASMDWSYALLTESERALFRRLSAI
MSMEG_4339|M.smegmatis_MC2_155      LEARAAHSRAEWAAAYQAYLRAEAIGPMTLDDLDAYATTAWRLGHSREAV
                                                                                      

Mflv_4288|M.gilvum_PYR-GCK          WIGCHADSHEYARWFGDDIAVRRDSYLVDWSGLPYLRFLMANTGRGQPVL
Mvan_2058|M.vanbaalenii_PYR-1       WIGCHADSHEYAHWFGDDIAVRHDSYLVDWTGLPYLRFLMANTGRGQPLL
MAV_4201|M.avium_104                WVGCHADSHEYARWFGDDIAVRHDSYLVDWSGIPYLRFLASNVGRGQPLA
MMAR_3959|M.marinum_M               --------------------------------------------------
MUL_3814|M.ulcerans_Agy99           --------------------------------------------------
TH_3563|M.thermoresistible__bu      --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997      --------------------------------------------------
Mb2515c|M.bovis_AF2122/97           PSGFDLDGAQAAAAGGDVQRYEVVDLLSLLADKSLVVTDDSDGRTRYRLL
Rv2488c|M.tuberculosis_H37Rv        PSGFDLDGAQAAAAGGDVQRYEVVDLLSLLADKSLVVTDDSDGRTRYRLL
MLBr_01753|M.leprae_Br4923          SGTFDLKVAYAVGHDDLEEPDQVFDRLTMLIDKSLVIVEGRQGGSRYRLL
MSMEG_4339|M.smegmatis_MC2_155      RLAERVYG-QLVRRDPATAATKAVDIALEWLTRGDLNIAQGWMNRARRLL
                                                                                      

Mflv_4288|M.gilvum_PYR-GCK          RRLSVLATLLADARGQIAELIHSHCSSAGILADRLGLS------------
Mvan_2058|M.vanbaalenii_PYR-1       HRLSLMATLLADARGQISQLIHSHCASAGMLADRLGVS------------
MAV_4201|M.avium_104                HRLSVMATLFANARGHISRLIHSHCASAALLADRIGLG------------
MMAR_3959|M.marinum_M               --------------------MSEHESPTVMVVDDH---------------
MUL_3814|M.ulcerans_Agy99           --------------------MSEHESPTVMVVDDH---------------
TH_3563|M.thermoresistible__bu      --------------------MGEPQQPTVMVVDDH---------------
MAB_1522|M.abscessus_ATCC_1997      --------------------MTDTEVG-VLLVDDQ---------------
Mb2515c|M.bovis_AF2122/97           ETVRQYALEKLRESGDADAVRARHRDHYAAVAAGLDAPSVAGHERRLNQA
Rv2488c|M.tuberculosis_H37Rv        ETVRQYALEKLRESGDADAVRARHRDHYAAVAAGLDAPSVAGHERRLNQA
MLBr_01753|M.leprae_Br4923          ETVRQYAMKKLEESNEVDLVLARHRDHYMALGALLDTPGDIDHEQLVEQV
MSMEG_4339|M.smegmatis_MC2_155      TGAPTGPTHCYLAYLDVVLAVAEQDPEELARRAEAVRH------------
                                                                                      

Mflv_4288|M.gilvum_PYR-GCK          ----ADVQTVLGYTFERFDGGGLPGGVG----------------------
Mvan_2058|M.vanbaalenii_PYR-1       ----AEVQSALGSTFERYDGGGLPGGVG----------------------
MAV_4201|M.avium_104                ----PNVQAALAYTFERYDGGGLPTGAR----------------------
MMAR_3959|M.marinum_M               ----PIWRDAVARDLS-DDGFAVVATAD----------------------
MUL_3814|M.ulcerans_Agy99           ----PIWRDAVARDLS-DDGFAVVATAD----------------------
TH_3563|M.thermoresistible__bu      ----PIWREAVARDLA-EAGLSVVATAD----------------------
MAB_1522|M.abscessus_ATCC_1997      ----ELVRTGLRRILRRKDGFAIVGECA----------------------
Mb2515c|M.bovis_AF2122/97           ELEIDNLRAAFAFSRENGDTGHALLLASCLQPLWRARGRLQEGLAWFAAA
Rv2488c|M.tuberculosis_H37Rv        ELEIDNLRAAFAFSRENGDTGHALLLASCLQPLWRARGRLQEGLAWFAAA
MLBr_01753|M.leprae_Br4923          ETELDNLRSAFAWSRETGDIAGALQLASSLQPIWFGRGHMYEGLAWFDSI
MSMEG_4339|M.smegmatis_MC2_155      --LCDSVEDPALESLSLVSQAIAALHQG----------------------
                                           .                                          

Mflv_4288|M.gilvum_PYR-GCK          -----------------------------------------GDAIPIPMR
Mvan_2058|M.vanbaalenii_PYR-1       -----------------------------------------GDDIPLPMR
MAV_4201|M.avium_104                -----------------------------------------GEDIPIQMR
MMAR_3959|M.marinum_M               -----------------------------------------GVATAQRRA
MUL_3814|M.ulcerans_Agy99           -----------------------------------------GVATAQRRA
TH_3563|M.thermoresistible__bu      -----------------------------------------GVAAARRRA
MAB_1522|M.abscessus_ATCC_1997      -----------------------------------------DGSEVAAAV
Mb2515c|M.bovis_AF2122/97           LADHDAHPAGADPGLYARALADRALIDAVAG-----ITDRLDDAQKALAI
Rv2488c|M.tuberculosis_H37Rv        LADHDAHPAGADPGLYARALADRALIDAVAG-----ITDRLDDAQKALAI
MLBr_01753|M.leprae_Br4923          FEHKNIEHLVAPKEVLARAVANKVMLHAILASSPPDGSDLVTQAQQALTM
MSMEG_4339|M.smegmatis_MC2_155      -----------------------------------------RVADGYALV
                                                                                      

Mflv_4288|M.gilvum_PYR-GCK          VAQLADTAEVHHRTFGV---------------DGAVAMARSRSGGQFDPR
Mvan_2058|M.vanbaalenii_PYR-1       VAQLADMVEVHHRAYGV---------------DGAVAMARSRRGGQFDPR
MAV_4201|M.avium_104                IAQLADMVEVHHRSYGV---------------AGAVAMVGARRGGQFDPG
MMAR_3959|M.marinum_M               AIVKPDVVVMDMRLADG---------------DGVQATT-----------
MUL_3814|M.ulcerans_Agy99           AIVKPDVVVMDMRLADG---------------DGVQATT-----------
TH_3563|M.thermoresistible__bu      AAVRPDVVLMDMRLPDG---------------DGARATA-----------
MAB_1522|M.abscessus_ATCC_1997      SRARPDVVIMDLRMKQM---------------SGIEAIR-----------
Mb2515c|M.bovis_AF2122/97           ARDIEDPALLARALTACGGVAAYNADLARPWLAEAVGLARAVGDKWRLAE
Rv2488c|M.tuberculosis_H37Rv        ARDIEDPALLARALTACGGVAAYNADLARPWLAEAVGLARAVGDKWRLAE
MLBr_01753|M.leprae_Br4923          AREIGDSAVLARALTACGFSSGYDTEVARPYFAEAVELARTQGDKWTLSQ
MSMEG_4339|M.smegmatis_MC2_155      DEALLPLLAGHVRVEWAG-------DIYCVVLNLCHKLADHPRMRAWTQS
                                                                                      

Mflv_4288|M.gilvum_PYR-GCK          VVDAFLADADAILEPPE--DAWSAALREAPDYGTGLADGELDELLVALGD
Mvan_2058|M.vanbaalenii_PYR-1       VVDAFTADAVTVLSVPAPGDAWTVALREAPDYGERLHGAELDALLVALGD
MAV_4201|M.avium_104                IADVFLRDADAILAGPQTGDAWAAALREAPDR-HRVDEQSLDAALVALGD
MMAR_3959|M.marinum_M               ----------------------------------EVLKVSPATRVLVLSA
MUL_3814|M.ulcerans_Agy99           ----------------------------------EVLKVSPATRVLVLST
TH_3563|M.thermoresistible__bu      ----------------------------------EVRAVSPDSRVLVLSA
MAB_1522|M.abscessus_ATCC_1997      ----------------------------------LLHAAQ-GPPALALTT
Mb2515c|M.bovis_AF2122/97           VLAWQAYVGFAGEGDPGATRAAGEEARSLADEIGDAFLSRSCRWALAAAN
Rv2488c|M.tuberculosis_H37Rv        VLAWQAYVGFAGEGDPGATRAAGEEARSLADEIGDAFLSRSCRWALAAAN
MLBr_01753|M.leprae_Br4923          IRLWG-VVGFCVSGDPVALRAAAEAADDLAQEIGDRFVSLQCRLLLSIAQ
MSMEG_4339|M.smegmatis_MC2_155      MERWCDVHSASPFYRVCDVHRLQLAAADDDYRRLEDQLFSASTALEDVNS
                                                                                      

Mflv_4288|M.gilvum_PYR-GCK          FVDLKCPFTLGHSRAVAELAAGAAALMGMD---AGGVDLLRRAGHVHDVG
Mvan_2058|M.vanbaalenii_PYR-1       FVDLKCPFTLGHSRAVAELAAGAAAVVGLD---ADTVTVVRRAGHLHDLG
MAV_4201|M.avium_104                FVDLKCPFTLGHSRAVARLAGQAARAAGLD---ADAVALTRRAGHVHDLG
MMAR_3959|M.marinum_M               SDERED--------VLEAVKAGATGYLVKS---ASKAELADAVRATAAG-
MUL_3814|M.ulcerans_Agy99           SDERED--------VLEAVKTGATGYLVKS---ASKAELADAVRATAAG-
TH_3563|M.thermoresistible__bu      SEERDD--------VLEAVKAGATGYLVKS---ASKTELVDAVHATAQG-
MAB_1522|M.abscessus_ATCC_1997      FDDDEL--------LSGALRAGAAGFILKD---SPAEELVRAVHAVARG-
Mb2515c|M.bovis_AF2122/97           LWQGNLEAAVGLSREVIGESDAAHDMVSSC---AGQACLAHALAHRGDTE
Rv2488c|M.tuberculosis_H37Rv        LWQGNLEAAVGLSREVIGESDAAHDMVSSC---AGQACLAHALAHRGDTE
MLBr_01753|M.leprae_Br4923          LWQGDMDGAIVRSGEVVAGAEAAHDTVTRT---FGLYVQTRALVHRDVSA
MSMEG_4339|M.smegmatis_MC2_155      WVGAEGFYQLGEVRRLRGDTEGALAAFAKARSLGKDPQPGEALLHCSVGQ
                                        .                 *                           

Mflv_4288|M.gilvum_PYR-GCK          RIGVSNQVWSKPSTLTTGEMERVRLHPYLTVRILSQVGGLDAVARVAGNH
Mvan_2058|M.vanbaalenii_PYR-1       RIGVSNQIWSKPSSLTARELERVRLHPYLTVRILSQVGGLDAVAQVAGNH
MAV_4201|M.avium_104                RIGVSNQIWSRPGPLSGSQFERVRLHPYLTVRILDQVPGLRRLAEVAGNH
MMAR_3959|M.marinum_M               ---------------------RAVFTPSLAGLVLGEYRRIAQTADSS---
MUL_3814|M.ulcerans_Agy99           ---------------------RAVFTPSLAGLVLGEYRRIAQTADSS---
TH_3563|M.thermoresistible__bu      ---------------------RAVFTPGLAGLVLGEYRRISRQPGAG---
MAB_1522|M.abscessus_ATCC_1997      ---------------------EAYLDPAVTSRVLNAYRRAP-AAVSG---
Mb2515c|M.bovis_AF2122/97           AAAAAQASIDTAVGLSPVLSGSACSALVFATLAAGDVAAAEHARESATRF
Rv2488c|M.tuberculosis_H37Rv        AAAAAQASIDTAVGLSPVLSGSACSALVFATLAAGDVAAAEHARESATRF
MLBr_01753|M.leprae_Br4923          ALVTAGLVVEAAAELSGVYQGIGYAAMVFAALAMGDVAAAVEASEACRPH
MSMEG_4339|M.smegmatis_MC2_155      SRKAWTDLRVALAGAGPLDRMRLLRAAVVVALARDDIGEAQRYCDQLAAG
                                                                ..    .               

Mflv_4288|M.gilvum_PYR-GCK          HECLDGSGYPRGLPAAALSVPDRVLAAAVAYRSAVEPRPY----------
Mvan_2058|M.vanbaalenii_PYR-1       HEYLDGSGYPRGLPAAALSLPDRLLAAAVAYQSALEPRPY----------
MAV_4201|M.avium_104                HECLDGSGYPRGLAGSALGMPDRILAAAVCYQSGREPRPY----------
MMAR_3959|M.marinum_M               --------------------------------------------------
MUL_3814|M.ulcerans_Agy99           --------------------------------------------------
TH_3563|M.thermoresistible__bu      --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997      --------------------------------------------------
Mb2515c|M.bovis_AF2122/97           FGASAAAIINDPTSSAQISCARGDLNAAHRLADGAASITRGVHRARALTT
Rv2488c|M.tuberculosis_H37Rv        FGASAAAIINDPTSSAQISCARGDLNAAHRLADGAASITRGVHRARALTT
MLBr_01753|M.leprae_Br4923          LGADHGLVAIHLELMAAVALARGDVIVARRLADNSVSATTGWHQMAALTT
MSMEG_4339|M.smegmatis_MC2_155      AEAFATPGYRGWAAHARGAVLVRRGEFEAALDNLGAALREYRLQ------
                                                                                      

Mflv_4288|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2058|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_4201|M.avium_104                --------------------------------------------------
MMAR_3959|M.marinum_M               --------------------------------------------------
MUL_3814|M.ulcerans_Agy99           --------------------------------------------------
TH_3563|M.thermoresistible__bu      --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997      --------------------------------------------------
Mb2515c|M.bovis_AF2122/97           RCRIEIAQGDRHRAERDAHDALGVAASIGAYLWVPDILECLASVMADAGS
Rv2488c|M.tuberculosis_H37Rv        RCRIEIAQGDRHRAERDAHDALGVAASIGAYLWVPDILECLASVMADAGS
MLBr_01753|M.leprae_Br4923          RARIAMAQGEPELARADIHAALACGADIQASLGISDSMELLAELISQGDN
MSMEG_4339|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_4288|M.gilvum_PYR-GCK          ---------------------------------RVALSPAAAATRLRDRV
Mvan_2058|M.vanbaalenii_PYR-1       ---------------------------------RDPLPATSAAARLRERV
MAV_4201|M.avium_104                ---------------------------------REQLSEAEAARRLRGRV
MMAR_3959|M.marinum_M               --------------------------------------------------
MUL_3814|M.ulcerans_Agy99           --------------------------------------------------
TH_3563|M.thermoresistible__bu      --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997      --------------------------------------------------
Mb2515c|M.bovis_AF2122/97           NREAVRLFGAADAARGRMGAVRFGIYQAGCNSSLATLRKSMGDSEFDDAW
Rv2488c|M.tuberculosis_H37Rv        NREAVRLFGAADAARGRMGAVRFGIYQAGCNSSLATLRKSMGDSEFDDAW
MLBr_01753|M.leprae_Br4923          HRQAGRLFGAASAQREKTGEVRFKVWDAGYESAVAVLRGAMGCKDFDSAW
MSMEG_4339|M.smegmatis_MC2_155      --------------------------QERYDIAEVYEWMALAHRGLGDDT
                                                                                      

Mflv_4288|M.gilvum_PYR-GCK          REGHLDELAVDAVLSAAGHAAR-RVSARPGGLTPREIEVLCLVARGASNK
Mvan_2058|M.vanbaalenii_PYR-1       REGRLDEVAVEAVLQAAGHRAR-GHSPRPGGLTPREIEVLCLVARGASNK
MAV_4201|M.avium_104                RCGELDPVAAEAVLHAAGQPVGPRPNPRPDGLTPREIEVLGHVARGASNK
MMAR_3959|M.marinum_M               --------------------------QDRPSLTERETEILRYVAKGLSAK
MUL_3814|M.ulcerans_Agy99           --------------------------QDRPSLTERETEILRYVAKGLSAK
TH_3563|M.thermoresistible__bu      --------------------------PDAPRLTERETEILRYVAKGLTAK
MAB_1522|M.abscessus_ATCC_1997      --------------------------DAQDKLTARELDVLALIASGATNS
Mb2515c|M.bovis_AF2122/97           AEGTALSIDEAIAYAQRGRGARKRPTSGWGALTPTELEVALLVGEGLSNK
Rv2488c|M.tuberculosis_H37Rv        AEGTALSIDEAIAYAQRGRGARKRPTSGWGALTPTELEVALLVGEGLSNK
MLBr_01753|M.leprae_Br4923          AEGAAMPIDDAITYAQRGRGNRKRPTTGWESLTPAEHNVIRLVSEGLDTK
MSMEG_4339|M.smegmatis_MC2_155      AADTDIATAENIYEQLAVQPSGVCGRASPGGLTRREIEVLRAIAGGATNR
                                                                   **  * ::   :. *    

Mflv_4288|M.gilvum_PYR-GCK          EIAATLGISGKTARNHVERTYAKIGATNRIGASMFALGHGLITPA----
Mvan_2058|M.vanbaalenii_PYR-1       EIAATLGISGKTARNHVERTYAKIGATNRIGASMFALNHGLVAPA----
MAV_4201|M.avium_104                EIAAALVISEKTARNHVERTYAKIGVSNRIGASMYALQHGLVPAAPPHS
MMAR_3959|M.marinum_M               QIAEKLSLSHRTVENHVQATFRKLQVANRVELTRYAIEHGLDK------
MUL_3814|M.ulcerans_Agy99           QIAEKLSLSHRTVENHVQATFRKLQLANRVELTRYAIEHGLDK------
TH_3563|M.thermoresistible__bu      QIAAQLSLSHRTVENHVQATFRKLQVANRVELARYAIEHGLDE------
MAB_1522|M.abscessus_ATCC_1997      EIAEQLVISEVTVKSHIGRIFVKLDLRDRAAAIVYAYDHGIVTPK----
Mb2515c|M.bovis_AF2122/97           EIGVRLFISPRTVHSHLTHVYTKLGLSSRLQLAQQAARRGESERGPSRP
Rv2488c|M.tuberculosis_H37Rv        EIGVRLFISPRTVHSHLTHVYTKLGLSSRLQLAQQAARRGESERGPSRP
MLBr_01753|M.leprae_Br4923          DIAARLFVSVRTVHTHLTRIYSKLGLTSRVQLVQEAARHN---------
MSMEG_4339|M.smegmatis_MC2_155      QVAHQFVISDKTVGRHLANIYTKLGVSSRTAAVTWAYQNGVVRKDN---
                                    ::.  : :*  *.  *:   : *:   .*      *  ..