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MLMAQAVLPTRAELLAALSVAIDLGLGQPAEHMLRAALIATRLCDRLGLSRQQRDCVYYTTLVMWVGCHA DSHEYARWFGDDIAVRHDSYLVDWSGIPYLRFLASNVGRGQPLAHRLSVMATLFANARGHISRLIHSHCA SAALLADRIGLGPNVQAALAYTFERYDGGGLPTGARGEDIPIQMRIAQLADMVEVHHRSYGVAGAVAMVG ARRGGQFDPGIADVFLRDADAILAGPQTGDAWAAALREAPDRHRVDEQSLDAALVALGDFVDLKCPFTLG HSRAVARLAGQAARAAGLDADAVALTRRAGHVHDLGRIGVSNQIWSRPGPLSGSQFERVRLHPYLTVRIL DQVPGLRRLAEVAGNHHECLDGSGYPRGLAGSALGMPDRILAAAVCYQSGREPRPYREQLSEAEAARRLR GRVRCGELDPVAAEAVLHAAGQPVGPRPNPRPDGLTPREIEVLGHVARGASNKEIAAALVISEKTARNHV ERTYAKIGVSNRIGASMYALQHGLVPAAPPHS*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. avium 104 | MAV_4201 | - | - | 100% (523) | transcriptional regulator, LuxR family protein |
M. avium 104 | MAV_4114 | - | 2e-11 | 47.69% (65) | response regulator receiver domain-containing protein |
M. avium 104 | MAV_0872 | - | 5e-10 | 32.08% (106) | DNA-binding response regulator, LuxR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2515c | - | 8e-09 | 28.19% (188) | LuxR family transcriptional regulator |
M. gilvum PYR-GCK | Mflv_4288 | - | 0.0 | 71.23% (511) | metal dependent phosphohydrolase |
M. tuberculosis H37Rv | Rv2488c | - | 9e-09 | 28.19% (188) | LuxR family transcriptional regulator |
M. leprae Br4923 | MLBr_01753 | - | 8e-09 | 33.01% (103) | putative transcriptional regulator |
M. abscessus ATCC 19977 | MAB_1522 | - | 4e-13 | 40.19% (107) | putative two-component system response regulator LuxR |
M. marinum M | MMAR_3959 | - | 4e-11 | 48.33% (60) | two-component transcriptional regulatory protein |
M. smegmatis MC2 155 | MSMEG_4339 | - | 2e-15 | 30.30% (297) | TPR repeat-containing protein |
M. thermoresistible (build 8) | TH_3563 | - | 3e-12 | 43.84% (73) | PUTATIVE DNA-binding response regulator, LuxR family protein |
M. ulcerans Agy99 | MUL_3814 | - | 5e-11 | 46.67% (60) | two component transcriptional regulatory protein |
M. vanbaalenii PYR-1 | Mvan_2058 | - | 0.0 | 72.80% (511) | metal dependent phosphohydrolase |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_4288|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2058|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_4201|M.avium_104 -------------------------------------------------- MMAR_3959|M.marinum_M -------------------------------------------------- MUL_3814|M.ulcerans_Agy99 -------------------------------------------------- TH_3563|M.thermoresistible__bu -------------------------------------------------- MAB_1522|M.abscessus_ATCC_1997 -------------------------------------------------- Mb2515c|M.bovis_AF2122/97 MDRRPRDFEQSRRRCRCNALRAGSMLASMSKIHPGVDVVPVDWSADGVSE Rv2488c|M.tuberculosis_H37Rv MDRRPRDFEQSRRRCRCNALRAGSMLASMSKIHPGVDVVPVDWSADGVSE MLBr_01753|M.leprae_Br4923 ----------------MYSLGEMQKPVPVGADYLASCLVARLRSTDVPTD MSMEG_4339|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_4288|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2058|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_4201|M.avium_104 -------------------------------------------------- MMAR_3959|M.marinum_M -------------------------------------------------- MUL_3814|M.ulcerans_Agy99 -------------------------------------------------- TH_3563|M.thermoresistible__bu -------------------------------------------------- MAB_1522|M.abscessus_ATCC_1997 -------------------------------------------------- Mb2515c|M.bovis_AF2122/97 LVPTGTVTLLLADIEGATHLPGSQLD--TTAIAKLDRTLTELVREHRGVC Rv2488c|M.tuberculosis_H37Rv LVPTGTVTLLLADIEGATHLPGSQLD--TTAIAKLDRTLTELVREHRGVC MLBr_01753|M.leprae_Br4923 LHRGCTVTLFLGDVEGLAELSETQPDEAADAIARLDCVVSEAVAAHGGVQ MSMEG_4339|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_4288|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2058|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_4201|M.avium_104 -------------------------------------------------- MMAR_3959|M.marinum_M -------------------------------------------------- MUL_3814|M.ulcerans_Agy99 -------------------------------------------------- TH_3563|M.thermoresistible__bu -------------------------------------------------- MAB_1522|M.abscessus_ATCC_1997 -------------------------------------------------- Mb2515c|M.bovis_AF2122/97 PVEQGEGDSFLVAFARASDAVACALGLQRAPLAPIRLRIGMHTGEVSSP- Rv2488c|M.tuberculosis_H37Rv PVEQGEGDSFLVAFARASDAVACALGLQRAPLAPIRLRIGMHTGEVSSP- MLBr_01753|M.leprae_Br4923 QVVQGVRGNFLATFARASDATACALDLQLAPIVPVRFRIALHTGEVQISN MSMEG_4339|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_4288|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2058|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_4201|M.avium_104 -------------------------------------------------- MMAR_3959|M.marinum_M -------------------------------------------------- MUL_3814|M.ulcerans_Agy99 -------------------------------------------------- TH_3563|M.thermoresistible__bu -------------------------------------------------- MAB_1522|M.abscessus_ATCC_1997 -------------------------------------------------- Mb2515c|M.bovis_AF2122/97 DEGNCVGPTIDRTARLRELAHGGQTVLSGTTSDLVADLLPKDAWLNDLGT Rv2488c|M.tuberculosis_H37Rv DEGNCVGPTIDRTARLRELAHGGQTVLSGTTSDLVADLLPKDAWLNDLGT MLBr_01753|M.leprae_Br4923 DDVNNVVFMMVQAAGLLDLACGGQTVLSSITGDLVVDGLPADTWLVDLGS MSMEG_4339|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_4288|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2058|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_4201|M.avium_104 -------------------------------------------------- MMAR_3959|M.marinum_M -------------------------------------------------- MUL_3814|M.ulcerans_Agy99 -------------------------------------------------- TH_3563|M.thermoresistible__bu -------------------------------------------------- MAB_1522|M.abscessus_ATCC_1997 -------------------------------------------------- Mb2515c|M.bovis_AF2122/97 YRLDDLPRPERVVQLCHPDLHNAFPPLRTRKVVGAHCLPAQLTRLVGRVD Rv2488c|M.tuberculosis_H37Rv YRLDDLPRPERVVQLCHPDLHNAFPPLRTRKVVGAHCLPAQLTRLVGRVD MLBr_01753|M.leprae_Br4923 HLLRDLARPVRVMQLCHRNLRRNLHELGIRTVPGGPSLPVPLTTFVGRAA MSMEG_4339|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_4288|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2058|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_4201|M.avium_104 -------------------------------------------------- MMAR_3959|M.marinum_M -------------------------------------------------- MUL_3814|M.ulcerans_Agy99 -------------------------------------------------- TH_3563|M.thermoresistible__bu -------------------------------------------------- MAB_1522|M.abscessus_ATCC_1997 -------------------------------------------------- Mb2515c|M.bovis_AF2122/97 EVAQVRGLLDVKRWVTLTGVGGVGKTRLATQVASAVADGYPDGVWYVNLA Rv2488c|M.tuberculosis_H37Rv EVAQVRGLLDVKRWVTLTGVGGVGKTRLATQVASAVADGYPDGVWYVNLA MLBr_01753|M.leprae_Br4923 QIKELQELLTEKRLLTLVGPGGVGKTRLALQVVARVADEFSGELSYFDLA MSMEG_4339|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_4288|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2058|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_4201|M.avium_104 -------------------------------------------------- MMAR_3959|M.marinum_M -------------------------------------------------- MUL_3814|M.ulcerans_Agy99 -------------------------------------------------- TH_3563|M.thermoresistible__bu -------------------------------------------------- MAB_1522|M.abscessus_ATCC_1997 -------------------------------------------------- Mb2515c|M.bovis_AF2122/97 PITDPALVPIAAARVLGLPDQPGRSTVDTIVRRIGDRRMLVVLDNCEHLL Rv2488c|M.tuberculosis_H37Rv PITDPALVPIAAARVLGLPDQPGRSTVDTIVRRIGDRRMLVVLDNCEHLL MLBr_01753|M.leprae_Br4923 PDTDHDIFPIT--------------VLDNLRRCIGDRRMLMVLDNCEYLL MSMEG_4339|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_4288|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2058|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_4201|M.avium_104 -------------------------------------------------- MMAR_3959|M.marinum_M -------------------------------------------------- MUL_3814|M.ulcerans_Agy99 -------------------------------------------------- TH_3563|M.thermoresistible__bu -------------------------------------------------- MAB_1522|M.abscessus_ATCC_1997 -------------------------------------------------- Mb2515c|M.bovis_AF2122/97 DGCAALIVALLGACPALRVLATSREPIAVAGEQIWRVPPLG-HGEAIELF Rv2488c|M.tuberculosis_H37Rv DGCAALIVALLGACPALRVLATSREPIAVAGEQIWRVPPLG-HGEAIELF MLBr_01753|M.leprae_Br4923 DVCANVMTTLLGACPSLTILATSREPIGVAGEVIWRVSMLSPADEAVELF MSMEG_4339|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_4288|M.gilvum_PYR-GCK ---------------------------------MAPPAQPPVRTPSRAEL Mvan_2058|M.vanbaalenii_PYR-1 ---------------------------------MAPPAEHPARSPSRAEL MAV_4201|M.avium_104 ---------------------------------MMLMAQ--AVLPTRAEL MMAR_3959|M.marinum_M -------------------------------------------------- MUL_3814|M.ulcerans_Agy99 -------------------------------------------------- TH_3563|M.thermoresistible__bu -------------------------------------------------- MAB_1522|M.abscessus_ATCC_1997 -------------------------------------------------- Mb2515c|M.bovis_AF2122/97 TDRAREARPELEITADNLALVTEICHRLDGIPLAIELAASRVRALALTEI Rv2488c|M.tuberculosis_H37Rv TDRAREARPELEITADNLALVTEICHRLDGIPLAIELAASRVRALALTEI MLBr_01753|M.leprae_Br4923 TERAALVQPGFSVTDGNRQIVTEICQRLDGMPLAIELAAARIRTLSLTEI MSMEG_4339|M.smegmatis_MC2_155 ---------------------------------MTTATGSVGRASDHPAL Mflv_4288|M.gilvum_PYR-GCK LAALSIAIDLGLGQPAEHMLRSAVIATRIADRLGLDRAERDCTYYTALIM Mvan_2058|M.vanbaalenii_PYR-1 LAALSIAIDLGLGQPAEHMLRSAVIATRIAERLGLDRPQRDCCYYTALIM MAV_4201|M.avium_104 LAALSVAIDLGLGQPAEHMLRAALIATRLCDRLGLSRQQRDCVYYTTLVM MMAR_3959|M.marinum_M -------------------------------------------------- MUL_3814|M.ulcerans_Agy99 -------------------------------------------------- TH_3563|M.thermoresistible__bu -------------------------------------------------- MAB_1522|M.abscessus_ATCC_1997 -------------------------------------------------- Mb2515c|M.bovis_AF2122/97 VDSLHDRFRLLTGGSRIAVRRQQTMRASVDWSHALLTGPEQVLFRRLAVF Rv2488c|M.tuberculosis_H37Rv VDSLHDRFRLLTGGSRIAVRRQQTMRASVDWSHALLTGPEQVLFRRLAVF MLBr_01753|M.leprae_Br4923 ADGLDDRFRLLTGGARTAVRRQQTLRASMDWSYALLTESERALFRRLSAI MSMEG_4339|M.smegmatis_MC2_155 LEARAAHSRAEWAAAYQAYLRAEAIGPMTLDDLDAYATTAWRLGHSREAV Mflv_4288|M.gilvum_PYR-GCK WIGCHADSHEYARWFGDDIAVRRDSYLVDWSGLPYLRFLMANTGRGQPVL Mvan_2058|M.vanbaalenii_PYR-1 WIGCHADSHEYAHWFGDDIAVRHDSYLVDWTGLPYLRFLMANTGRGQPLL MAV_4201|M.avium_104 WVGCHADSHEYARWFGDDIAVRHDSYLVDWSGIPYLRFLASNVGRGQPLA MMAR_3959|M.marinum_M -------------------------------------------------- MUL_3814|M.ulcerans_Agy99 -------------------------------------------------- TH_3563|M.thermoresistible__bu -------------------------------------------------- MAB_1522|M.abscessus_ATCC_1997 -------------------------------------------------- Mb2515c|M.bovis_AF2122/97 PSGFDLDGAQAAAAGGDVQRYEVVDLLSLLADKSLVVTDDSDGRTRYRLL Rv2488c|M.tuberculosis_H37Rv PSGFDLDGAQAAAAGGDVQRYEVVDLLSLLADKSLVVTDDSDGRTRYRLL MLBr_01753|M.leprae_Br4923 SGTFDLKVAYAVGHDDLEEPDQVFDRLTMLIDKSLVIVEGRQGGSRYRLL MSMEG_4339|M.smegmatis_MC2_155 RLAERVYG-QLVRRDPATAATKAVDIALEWLTRGDLNIAQGWMNRARRLL Mflv_4288|M.gilvum_PYR-GCK RRLSVLATLLADARGQIAELIHSHCSSAGILADRLGLS------------ Mvan_2058|M.vanbaalenii_PYR-1 HRLSLMATLLADARGQISQLIHSHCASAGMLADRLGVS------------ MAV_4201|M.avium_104 HRLSVMATLFANARGHISRLIHSHCASAALLADRIGLG------------ MMAR_3959|M.marinum_M --------------------MSEHESPTVMVVDDH--------------- MUL_3814|M.ulcerans_Agy99 --------------------MSEHESPTVMVVDDH--------------- TH_3563|M.thermoresistible__bu --------------------MGEPQQPTVMVVDDH--------------- MAB_1522|M.abscessus_ATCC_1997 --------------------MTDTEVG-VLLVDDQ--------------- Mb2515c|M.bovis_AF2122/97 ETVRQYALEKLRESGDADAVRARHRDHYAAVAAGLDAPSVAGHERRLNQA Rv2488c|M.tuberculosis_H37Rv ETVRQYALEKLRESGDADAVRARHRDHYAAVAAGLDAPSVAGHERRLNQA MLBr_01753|M.leprae_Br4923 ETVRQYAMKKLEESNEVDLVLARHRDHYMALGALLDTPGDIDHEQLVEQV MSMEG_4339|M.smegmatis_MC2_155 TGAPTGPTHCYLAYLDVVLAVAEQDPEELARRAEAVRH------------ Mflv_4288|M.gilvum_PYR-GCK ----ADVQTVLGYTFERFDGGGLPGGVG---------------------- Mvan_2058|M.vanbaalenii_PYR-1 ----AEVQSALGSTFERYDGGGLPGGVG---------------------- MAV_4201|M.avium_104 ----PNVQAALAYTFERYDGGGLPTGAR---------------------- MMAR_3959|M.marinum_M ----PIWRDAVARDLS-DDGFAVVATAD---------------------- MUL_3814|M.ulcerans_Agy99 ----PIWRDAVARDLS-DDGFAVVATAD---------------------- TH_3563|M.thermoresistible__bu ----PIWREAVARDLA-EAGLSVVATAD---------------------- MAB_1522|M.abscessus_ATCC_1997 ----ELVRTGLRRILRRKDGFAIVGECA---------------------- Mb2515c|M.bovis_AF2122/97 ELEIDNLRAAFAFSRENGDTGHALLLASCLQPLWRARGRLQEGLAWFAAA Rv2488c|M.tuberculosis_H37Rv ELEIDNLRAAFAFSRENGDTGHALLLASCLQPLWRARGRLQEGLAWFAAA MLBr_01753|M.leprae_Br4923 ETELDNLRSAFAWSRETGDIAGALQLASSLQPIWFGRGHMYEGLAWFDSI MSMEG_4339|M.smegmatis_MC2_155 --LCDSVEDPALESLSLVSQAIAALHQG---------------------- . Mflv_4288|M.gilvum_PYR-GCK -----------------------------------------GDAIPIPMR Mvan_2058|M.vanbaalenii_PYR-1 -----------------------------------------GDDIPLPMR MAV_4201|M.avium_104 -----------------------------------------GEDIPIQMR MMAR_3959|M.marinum_M -----------------------------------------GVATAQRRA MUL_3814|M.ulcerans_Agy99 -----------------------------------------GVATAQRRA TH_3563|M.thermoresistible__bu -----------------------------------------GVAAARRRA MAB_1522|M.abscessus_ATCC_1997 -----------------------------------------DGSEVAAAV Mb2515c|M.bovis_AF2122/97 LADHDAHPAGADPGLYARALADRALIDAVAG-----ITDRLDDAQKALAI Rv2488c|M.tuberculosis_H37Rv LADHDAHPAGADPGLYARALADRALIDAVAG-----ITDRLDDAQKALAI MLBr_01753|M.leprae_Br4923 FEHKNIEHLVAPKEVLARAVANKVMLHAILASSPPDGSDLVTQAQQALTM MSMEG_4339|M.smegmatis_MC2_155 -----------------------------------------RVADGYALV Mflv_4288|M.gilvum_PYR-GCK VAQLADTAEVHHRTFGV---------------DGAVAMARSRSGGQFDPR Mvan_2058|M.vanbaalenii_PYR-1 VAQLADMVEVHHRAYGV---------------DGAVAMARSRRGGQFDPR MAV_4201|M.avium_104 IAQLADMVEVHHRSYGV---------------AGAVAMVGARRGGQFDPG MMAR_3959|M.marinum_M AIVKPDVVVMDMRLADG---------------DGVQATT----------- MUL_3814|M.ulcerans_Agy99 AIVKPDVVVMDMRLADG---------------DGVQATT----------- TH_3563|M.thermoresistible__bu AAVRPDVVLMDMRLPDG---------------DGARATA----------- MAB_1522|M.abscessus_ATCC_1997 SRARPDVVIMDLRMKQM---------------SGIEAIR----------- Mb2515c|M.bovis_AF2122/97 ARDIEDPALLARALTACGGVAAYNADLARPWLAEAVGLARAVGDKWRLAE Rv2488c|M.tuberculosis_H37Rv ARDIEDPALLARALTACGGVAAYNADLARPWLAEAVGLARAVGDKWRLAE MLBr_01753|M.leprae_Br4923 AREIGDSAVLARALTACGFSSGYDTEVARPYFAEAVELARTQGDKWTLSQ MSMEG_4339|M.smegmatis_MC2_155 DEALLPLLAGHVRVEWAG-------DIYCVVLNLCHKLADHPRMRAWTQS Mflv_4288|M.gilvum_PYR-GCK VVDAFLADADAILEPPE--DAWSAALREAPDYGTGLADGELDELLVALGD Mvan_2058|M.vanbaalenii_PYR-1 VVDAFTADAVTVLSVPAPGDAWTVALREAPDYGERLHGAELDALLVALGD MAV_4201|M.avium_104 IADVFLRDADAILAGPQTGDAWAAALREAPDR-HRVDEQSLDAALVALGD MMAR_3959|M.marinum_M ----------------------------------EVLKVSPATRVLVLSA MUL_3814|M.ulcerans_Agy99 ----------------------------------EVLKVSPATRVLVLST TH_3563|M.thermoresistible__bu ----------------------------------EVRAVSPDSRVLVLSA MAB_1522|M.abscessus_ATCC_1997 ----------------------------------LLHAAQ-GPPALALTT Mb2515c|M.bovis_AF2122/97 VLAWQAYVGFAGEGDPGATRAAGEEARSLADEIGDAFLSRSCRWALAAAN Rv2488c|M.tuberculosis_H37Rv VLAWQAYVGFAGEGDPGATRAAGEEARSLADEIGDAFLSRSCRWALAAAN MLBr_01753|M.leprae_Br4923 IRLWG-VVGFCVSGDPVALRAAAEAADDLAQEIGDRFVSLQCRLLLSIAQ MSMEG_4339|M.smegmatis_MC2_155 MERWCDVHSASPFYRVCDVHRLQLAAADDDYRRLEDQLFSASTALEDVNS Mflv_4288|M.gilvum_PYR-GCK FVDLKCPFTLGHSRAVAELAAGAAALMGMD---AGGVDLLRRAGHVHDVG Mvan_2058|M.vanbaalenii_PYR-1 FVDLKCPFTLGHSRAVAELAAGAAAVVGLD---ADTVTVVRRAGHLHDLG MAV_4201|M.avium_104 FVDLKCPFTLGHSRAVARLAGQAARAAGLD---ADAVALTRRAGHVHDLG MMAR_3959|M.marinum_M SDERED--------VLEAVKAGATGYLVKS---ASKAELADAVRATAAG- MUL_3814|M.ulcerans_Agy99 SDERED--------VLEAVKTGATGYLVKS---ASKAELADAVRATAAG- TH_3563|M.thermoresistible__bu SEERDD--------VLEAVKAGATGYLVKS---ASKTELVDAVHATAQG- MAB_1522|M.abscessus_ATCC_1997 FDDDEL--------LSGALRAGAAGFILKD---SPAEELVRAVHAVARG- Mb2515c|M.bovis_AF2122/97 LWQGNLEAAVGLSREVIGESDAAHDMVSSC---AGQACLAHALAHRGDTE Rv2488c|M.tuberculosis_H37Rv LWQGNLEAAVGLSREVIGESDAAHDMVSSC---AGQACLAHALAHRGDTE MLBr_01753|M.leprae_Br4923 LWQGDMDGAIVRSGEVVAGAEAAHDTVTRT---FGLYVQTRALVHRDVSA MSMEG_4339|M.smegmatis_MC2_155 WVGAEGFYQLGEVRRLRGDTEGALAAFAKARSLGKDPQPGEALLHCSVGQ . * Mflv_4288|M.gilvum_PYR-GCK RIGVSNQVWSKPSTLTTGEMERVRLHPYLTVRILSQVGGLDAVARVAGNH Mvan_2058|M.vanbaalenii_PYR-1 RIGVSNQIWSKPSSLTARELERVRLHPYLTVRILSQVGGLDAVAQVAGNH MAV_4201|M.avium_104 RIGVSNQIWSRPGPLSGSQFERVRLHPYLTVRILDQVPGLRRLAEVAGNH MMAR_3959|M.marinum_M ---------------------RAVFTPSLAGLVLGEYRRIAQTADSS--- MUL_3814|M.ulcerans_Agy99 ---------------------RAVFTPSLAGLVLGEYRRIAQTADSS--- TH_3563|M.thermoresistible__bu ---------------------RAVFTPGLAGLVLGEYRRISRQPGAG--- MAB_1522|M.abscessus_ATCC_1997 ---------------------EAYLDPAVTSRVLNAYRRAP-AAVSG--- Mb2515c|M.bovis_AF2122/97 AAAAAQASIDTAVGLSPVLSGSACSALVFATLAAGDVAAAEHARESATRF Rv2488c|M.tuberculosis_H37Rv AAAAAQASIDTAVGLSPVLSGSACSALVFATLAAGDVAAAEHARESATRF MLBr_01753|M.leprae_Br4923 ALVTAGLVVEAAAELSGVYQGIGYAAMVFAALAMGDVAAAVEASEACRPH MSMEG_4339|M.smegmatis_MC2_155 SRKAWTDLRVALAGAGPLDRMRLLRAAVVVALARDDIGEAQRYCDQLAAG .. . Mflv_4288|M.gilvum_PYR-GCK HECLDGSGYPRGLPAAALSVPDRVLAAAVAYRSAVEPRPY---------- Mvan_2058|M.vanbaalenii_PYR-1 HEYLDGSGYPRGLPAAALSLPDRLLAAAVAYQSALEPRPY---------- MAV_4201|M.avium_104 HECLDGSGYPRGLAGSALGMPDRILAAAVCYQSGREPRPY---------- MMAR_3959|M.marinum_M -------------------------------------------------- MUL_3814|M.ulcerans_Agy99 -------------------------------------------------- TH_3563|M.thermoresistible__bu -------------------------------------------------- MAB_1522|M.abscessus_ATCC_1997 -------------------------------------------------- Mb2515c|M.bovis_AF2122/97 FGASAAAIINDPTSSAQISCARGDLNAAHRLADGAASITRGVHRARALTT Rv2488c|M.tuberculosis_H37Rv FGASAAAIINDPTSSAQISCARGDLNAAHRLADGAASITRGVHRARALTT MLBr_01753|M.leprae_Br4923 LGADHGLVAIHLELMAAVALARGDVIVARRLADNSVSATTGWHQMAALTT MSMEG_4339|M.smegmatis_MC2_155 AEAFATPGYRGWAAHARGAVLVRRGEFEAALDNLGAALREYRLQ------ Mflv_4288|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2058|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_4201|M.avium_104 -------------------------------------------------- MMAR_3959|M.marinum_M -------------------------------------------------- MUL_3814|M.ulcerans_Agy99 -------------------------------------------------- TH_3563|M.thermoresistible__bu -------------------------------------------------- MAB_1522|M.abscessus_ATCC_1997 -------------------------------------------------- Mb2515c|M.bovis_AF2122/97 RCRIEIAQGDRHRAERDAHDALGVAASIGAYLWVPDILECLASVMADAGS Rv2488c|M.tuberculosis_H37Rv RCRIEIAQGDRHRAERDAHDALGVAASIGAYLWVPDILECLASVMADAGS MLBr_01753|M.leprae_Br4923 RARIAMAQGEPELARADIHAALACGADIQASLGISDSMELLAELISQGDN MSMEG_4339|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_4288|M.gilvum_PYR-GCK ---------------------------------RVALSPAAAATRLRDRV Mvan_2058|M.vanbaalenii_PYR-1 ---------------------------------RDPLPATSAAARLRERV MAV_4201|M.avium_104 ---------------------------------REQLSEAEAARRLRGRV MMAR_3959|M.marinum_M -------------------------------------------------- MUL_3814|M.ulcerans_Agy99 -------------------------------------------------- TH_3563|M.thermoresistible__bu -------------------------------------------------- MAB_1522|M.abscessus_ATCC_1997 -------------------------------------------------- Mb2515c|M.bovis_AF2122/97 NREAVRLFGAADAARGRMGAVRFGIYQAGCNSSLATLRKSMGDSEFDDAW Rv2488c|M.tuberculosis_H37Rv NREAVRLFGAADAARGRMGAVRFGIYQAGCNSSLATLRKSMGDSEFDDAW MLBr_01753|M.leprae_Br4923 HRQAGRLFGAASAQREKTGEVRFKVWDAGYESAVAVLRGAMGCKDFDSAW MSMEG_4339|M.smegmatis_MC2_155 --------------------------QERYDIAEVYEWMALAHRGLGDDT Mflv_4288|M.gilvum_PYR-GCK REGHLDELAVDAVLSAAGHAAR-RVSARPGGLTPREIEVLCLVARGASNK Mvan_2058|M.vanbaalenii_PYR-1 REGRLDEVAVEAVLQAAGHRAR-GHSPRPGGLTPREIEVLCLVARGASNK MAV_4201|M.avium_104 RCGELDPVAAEAVLHAAGQPVGPRPNPRPDGLTPREIEVLGHVARGASNK MMAR_3959|M.marinum_M --------------------------QDRPSLTERETEILRYVAKGLSAK MUL_3814|M.ulcerans_Agy99 --------------------------QDRPSLTERETEILRYVAKGLSAK TH_3563|M.thermoresistible__bu --------------------------PDAPRLTERETEILRYVAKGLTAK MAB_1522|M.abscessus_ATCC_1997 --------------------------DAQDKLTARELDVLALIASGATNS Mb2515c|M.bovis_AF2122/97 AEGTALSIDEAIAYAQRGRGARKRPTSGWGALTPTELEVALLVGEGLSNK Rv2488c|M.tuberculosis_H37Rv AEGTALSIDEAIAYAQRGRGARKRPTSGWGALTPTELEVALLVGEGLSNK MLBr_01753|M.leprae_Br4923 AEGAAMPIDDAITYAQRGRGNRKRPTTGWESLTPAEHNVIRLVSEGLDTK MSMEG_4339|M.smegmatis_MC2_155 AADTDIATAENIYEQLAVQPSGVCGRASPGGLTRREIEVLRAIAGGATNR ** * :: :. * Mflv_4288|M.gilvum_PYR-GCK EIAATLGISGKTARNHVERTYAKIGATNRIGASMFALGHGLITPA---- Mvan_2058|M.vanbaalenii_PYR-1 EIAATLGISGKTARNHVERTYAKIGATNRIGASMFALNHGLVAPA---- MAV_4201|M.avium_104 EIAAALVISEKTARNHVERTYAKIGVSNRIGASMYALQHGLVPAAPPHS MMAR_3959|M.marinum_M QIAEKLSLSHRTVENHVQATFRKLQVANRVELTRYAIEHGLDK------ MUL_3814|M.ulcerans_Agy99 QIAEKLSLSHRTVENHVQATFRKLQLANRVELTRYAIEHGLDK------ TH_3563|M.thermoresistible__bu QIAAQLSLSHRTVENHVQATFRKLQVANRVELARYAIEHGLDE------ MAB_1522|M.abscessus_ATCC_1997 EIAEQLVISEVTVKSHIGRIFVKLDLRDRAAAIVYAYDHGIVTPK---- Mb2515c|M.bovis_AF2122/97 EIGVRLFISPRTVHSHLTHVYTKLGLSSRLQLAQQAARRGESERGPSRP Rv2488c|M.tuberculosis_H37Rv EIGVRLFISPRTVHSHLTHVYTKLGLSSRLQLAQQAARRGESERGPSRP MLBr_01753|M.leprae_Br4923 DIAARLFVSVRTVHTHLTRIYSKLGLTSRVQLVQEAARHN--------- MSMEG_4339|M.smegmatis_MC2_155 QVAHQFVISDKTVGRHLANIYTKLGVSSRTAAVTWAYQNGVVRKDN--- ::. : :* *. *: : *: .* * ..