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APPAQPPVRTPSRAELLAALSIAIDLGLGQPAEHMLRSAVIATRIADRLGLDRAERDCTYYTALIMWIGC HADSHEYARWFGDDIAVRRDSYLVDWSGLPYLRFLMANTGRGQPVLRRLSVLATLLADARGQIAELIHSH CSSAGILADRLGLSADVQTVLGYTFERFDGGGLPGGVGGDAIPIPMRVAQLADTAEVHHRTFGVDGAVAM ARSRSGGQFDPRVVDAFLADADAILEPPEDAWSAALREAPDYGTGLADGELDELLVALGDFVDLKCPFTL GHSRAVAELAAGAAALMGMDAGGVDLLRRAGHVHDVGRIGVSNQVWSKPSTLTTGEMERVRLHPYLTVRI LSQVGGLDAVARVAGNHHECLDGSGYPRGLPAAALSVPDRVLAAAVAYRSAVEPRPYRVALSPAAAATRL RDRVREGHLDELAVDAVLSAAGHAARRVSARPGGLTPREIEVLCLVARGASNKEIAATLGISGKTARNHV ERTYAKIGATNRIGASMFALGHGLITPA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4288 | - | - | 100% (519) | metal dependent phosphohydrolase |
| M. gilvum PYR-GCK | Mflv_1688 | - | 2e-09 | 44.62% (65) | response regulator receiver protein |
| M. gilvum PYR-GCK | Mflv_3579 | - | 6e-09 | 43.33% (60) | two component LuxR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0914c | - | 3e-09 | 32.80% (125) | LuxR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0386 | - | 3e-09 | 32.19% (146) | LuxR/UHPA family transcriptional regulator |
| M. leprae Br4923 | MLBr_01753 | - | 1e-06 | 41.38% (58) | putative transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1522 | - | 9e-13 | 35.17% (145) | putative two-component system response regulator LuxR |
| M. marinum M | MMAR_3959 | - | 3e-09 | 45.00% (60) | two-component transcriptional regulatory protein |
| M. avium 104 | MAV_4201 | - | 0.0 | 71.23% (511) | transcriptional regulator, LuxR family protein |
| M. smegmatis MC2 155 | MSMEG_0856 | - | 6e-11 | 44.19% (86) | DNA-binding response regulator, LuxR family protein |
| M. thermoresistible (build 8) | TH_3563 | - | 8e-12 | 32.91% (158) | PUTATIVE DNA-binding response regulator, LuxR family protein |
| M. ulcerans Agy99 | MUL_3814 | - | 3e-09 | 45.00% (60) | two component transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_2058 | - | 0.0 | 82.92% (521) | metal dependent phosphohydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4288|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2058|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4201|M.avium_104 --------------------------------------------------
MMAR_3959|M.marinum_M --------------------------------------------------
MUL_3814|M.ulcerans_Agy99 --------------------------------------------------
TH_3563|M.thermoresistible__bu --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0856|M.smegmatis_MC2_155 --------------------------------------------------
Mb0914c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01753|M.leprae_Br4923 MYSLGEMQKPVPVGADYLASCLVARLRSTDVPTDLHRGCTVTLFLGDVEG
Rv0386|M.tuberculosis_H37Rv ------MSKLLPRG-------------------------TVTLLLADVEG
Mflv_4288|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2058|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4201|M.avium_104 --------------------------------------------------
MMAR_3959|M.marinum_M --------------------------------------------------
MUL_3814|M.ulcerans_Agy99 --------------------------------------------------
TH_3563|M.thermoresistible__bu --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0856|M.smegmatis_MC2_155 --------------------------------------------------
Mb0914c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01753|M.leprae_Br4923 LAELSETQPDEAADAIARLDCVVSEAVAAHGGVQQVVQGVRGNFLATFAR
Rv0386|M.tuberculosis_H37Rv STWLWETHPDDMGAAVARLDKAVSGVIAAHDGVRPVEQGEGDSFVLAFAC
Mflv_4288|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2058|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4201|M.avium_104 --------------------------------------------------
MMAR_3959|M.marinum_M --------------------------------------------------
MUL_3814|M.ulcerans_Agy99 --------------------------------------------------
TH_3563|M.thermoresistible__bu --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0856|M.smegmatis_MC2_155 --------------------------------------------------
Mb0914c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01753|M.leprae_Br4923 ASDATACALDLQLAPIVPVRFRIALHTGEVQISNDDVNNVVFMMVQAAGL
Rv0386|M.tuberculosis_H37Rv ASDAVAAALDLQRARLAPIRLRIGVHTGEVALR-DEGNYAGPTINRTARL
Mflv_4288|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2058|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4201|M.avium_104 --------------------------------------------------
MMAR_3959|M.marinum_M --------------------------------------------------
MUL_3814|M.ulcerans_Agy99 --------------------------------------------------
TH_3563|M.thermoresistible__bu --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0856|M.smegmatis_MC2_155 --------------------------------------------------
Mb0914c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01753|M.leprae_Br4923 LDLACGGQTVLSSITGDLVVDGLPADTWLVDLGSHLLRDLARPVRVMQLC
Rv0386|M.tuberculosis_H37Rv RDLAHGGQTVLSGVTESLVIDRLPDKAWLVDLGTHALRDLSRPERVMQLC
Mflv_4288|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2058|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4201|M.avium_104 --------------------------------------------------
MMAR_3959|M.marinum_M --------------------------------------------------
MUL_3814|M.ulcerans_Agy99 --------------------------------------------------
TH_3563|M.thermoresistible__bu --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0856|M.smegmatis_MC2_155 --------------------------------------------------
Mb0914c|M.bovis_AF2122/97 --------------------------------------MRALLAQNRLVT
MLBr_01753|M.leprae_Br4923 HRNLRRNLHELGIRTVPGGPSLPVPLTTFVGRAAQIKELQELLTEKRLLT
Rv0386|M.tuberculosis_H37Rv HPELRIDFPPLRVANDDVAHGLPVHLTRFVGRGAQITEVHRLVTDNRLVT
Mflv_4288|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2058|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4201|M.avium_104 --------------------------------------------------
MMAR_3959|M.marinum_M --------------------------------------------------
MUL_3814|M.ulcerans_Agy99 --------------------------------------------------
TH_3563|M.thermoresistible__bu --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0856|M.smegmatis_MC2_155 --------------------------------------------------
Mb0914c|M.bovis_AF2122/97 LCGTGGVGKTRLAIQIAS--ASELRDGLCFVDLAPITESGIVAATAARAV
MLBr_01753|M.leprae_Br4923 LVGPGGVGKTRLALQVVARVADEFSGELSYFDLAPDTDHDIFPIT-----
Rv0386|M.tuberculosis_H37Rv LTGAGGVGKTRLAAQLAAQIAGEFG-RAWFVDLAPITDPDLVPVTVAGAL
Mflv_4288|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2058|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4201|M.avium_104 --------------------------------------------------
MMAR_3959|M.marinum_M --------------------------------------------------
MUL_3814|M.ulcerans_Agy99 --------------------------------------------------
TH_3563|M.thermoresistible__bu --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0856|M.smegmatis_MC2_155 --------------------------------------------------
Mb0914c|M.bovis_AF2122/97 GLPDQPGRSTMDSLRRFIGNRRMLMVLDNCEHLLDACAALVVELLGACPE
MLBr_01753|M.leprae_Br4923 ---------VLDNLRRCIGDRRMLMVLDNCEYLLDVCANVMTTLLGACPS
Rv0386|M.tuberculosis_H37Rv GLHDQPGRSTTDTVLRFLGGRPALVVLDNCEHLLDATAALVLALVKACRG
Mflv_4288|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2058|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4201|M.avium_104 --------------------------------------------------
MMAR_3959|M.marinum_M --------------------------------------------------
MUL_3814|M.ulcerans_Agy99 --------------------------------------------------
TH_3563|M.thermoresistible__bu --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0856|M.smegmatis_MC2_155 --------------------------------------------------
Mb0914c|M.bovis_AF2122/97 LTILATSREPIGMAGEITWRVPSMSITDEAVELFADRASRVQPGFTIANH
MLBr_01753|M.leprae_Br4923 LTILATSREPIGVAGEVIWRVSMLSPADEAVELFTERAALVQPGFSVTDG
Rv0386|M.tuberculosis_H37Rv VRLLATCREPLRVEGEVSYRVPSLSLSDEAVEMFCYRAQRVRPDFRLTDD
Mflv_4288|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2058|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4201|M.avium_104 --------------------------------------------------
MMAR_3959|M.marinum_M --------------------------------------------------
MUL_3814|M.ulcerans_Agy99 --------------------------------------------------
TH_3563|M.thermoresistible__bu --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0856|M.smegmatis_MC2_155 --------------------------------------------------
Mb0914c|M.bovis_AF2122/97 NAAAVGEICRRLDGIPLAIEFAAARVRSMSPLEIADGLDDCFRLLAGGVR
MLBr_01753|M.leprae_Br4923 NRQIVTEICQRLDGMPLAIELAAARIRTLSLTEIADGLDDRFRLLTGGAR
Rv0386|M.tuberculosis_H37Rv NSAAVTEICKRLDGLPLAIELAAARLRSMTLDEIIDGLRDRFALLTGGAR
Mflv_4288|M.gilvum_PYR-GCK ----------------------------------------MAPPAQPPVR
Mvan_2058|M.vanbaalenii_PYR-1 ----------------------------------------MAPPAEHPAR
MAV_4201|M.avium_104 ----------------------------------------MMLMAQ--AV
MMAR_3959|M.marinum_M --------------------------------------------------
MUL_3814|M.ulcerans_Agy99 --------------------------------------------------
TH_3563|M.thermoresistible__bu --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0856|M.smegmatis_MC2_155 --------------------------------------------------
Mb0914c|M.bovis_AF2122/97 GAVQRQQTLRASIDWSHALLTETEQILFRRLAPFVGGFDLAAVRAVAAGS
MLBr_01753|M.leprae_Br4923 TAVRRQQTLRASMDWSYALLTESERALFRRLSAISGTFDLKVAYAVGHDD
Rv0386|M.tuberculosis_H37Rv TAAHRQQTLWASVDWSYTLLTEPERTLFRRLAVFVGCFFVDDAQAVACSG
Mflv_4288|M.gilvum_PYR-GCK TPSRAELLAALSIAIDLGLGQPAEHMLRSAVIATRIADRLGLDRAE----
Mvan_2058|M.vanbaalenii_PYR-1 SPSRAELLAALSIAIDLGLGQPAEHMLRSAVIATRIAERLGLDRPQ----
MAV_4201|M.avium_104 LPTRAELLAALSVAIDLGLGQPAEHMLRAALIATRLCDRLGLSRQQ----
MMAR_3959|M.marinum_M --------------------------------------------------
MUL_3814|M.ulcerans_Agy99 --------------------------------------------------
TH_3563|M.thermoresistible__bu --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0856|M.smegmatis_MC2_155 --------------------------------------------------
Mb0914c|M.bovis_AF2122/97 DLDPFSVLDQLTLLVDKSLVVADDCQGRTRYRLLETVRRYALEKLGDSGE
MLBr_01753|M.leprae_Br4923 LEEPDQVFDRLTMLIDKSLVIVEGRQGGSRYRLLETVRQYAMKKLEESNE
Rv0386|M.tuberculosis_H37Rv DVQRYQVLDEITLLVDKSLVMADDNSGRTCYRLCETMRHYALEKLSEAGE
Mflv_4288|M.gilvum_PYR-GCK ------RDCTYYTALIMWIG------------------------------
Mvan_2058|M.vanbaalenii_PYR-1 ------RDCCYYTALIMWIG------------------------------
MAV_4201|M.avium_104 ------RDCVYYTTLVMWVG------------------------------
MMAR_3959|M.marinum_M --------------------------------------------------
MUL_3814|M.ulcerans_Agy99 --------------------------------------------------
TH_3563|M.thermoresistible__bu --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0856|M.smegmatis_MC2_155 --------------------------------------------------
Mb0914c|M.bovis_AF2122/97 AD-VHARHRDYYTALAASLNTPADNDHQRLVARAETEIDNLRAAFAWSRE
MLBr_01753|M.leprae_Br4923 VDLVLARHRDHYMALGALLDTPGDIDHEQLVEQVETELDNLRSAFAWSRE
Rv0386|M.tuberculosis_H37Rv VDAVFARHRDYYTALAARVDNPGPSDYSHCLDQAETEIDNLRAAFVWNRE
Mflv_4288|M.gilvum_PYR-GCK -------CHADSHEYARWFGDDIAVRRDSYLVDWSGLPYLRFLMANTGRG
Mvan_2058|M.vanbaalenii_PYR-1 -------CHADSHEYAHWFGDDIAVRHDSYLVDWTGLPYLRFLMANTGRG
MAV_4201|M.avium_104 -------CHADSHEYARWFGDDIAVRHDSYLVDWSGIPYLRFLASNVGRG
MMAR_3959|M.marinum_M --------------------------------------------------
MUL_3814|M.ulcerans_Agy99 --------------------------------------------------
TH_3563|M.thermoresistible__bu --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0856|M.smegmatis_MC2_155 --------------------------------------------------
Mb0914c|M.bovis_AF2122/97 NGHITEALQLASSLQPIWFGRAHLREGLSWFNSILEDQRFHRLAVSTAVR
MLBr_01753|M.leprae_Br4923 TGDIAGALQLASSLQPIWFGRGHMYEGLAWFDSIFEHKNIEHLVAPKEVL
Rv0386|M.tuberculosis_H37Rv NSDTEGALALASSLLRVWMTRGRIQEGRAWFDSILADENARHLEVAAAVR
Mflv_4288|M.gilvum_PYR-GCK QPVLRRLSVLATLLADARGQIAELIHSHCSSAGILADRLGLSADVQTVLG
Mvan_2058|M.vanbaalenii_PYR-1 QPLLHRLSLMATLLADARGQISQLIHSHCASAGMLADRLGVSAEVQSALG
MAV_4201|M.avium_104 QPLAHRLSVMATLFANARGHISRLIHSHCASAALLADRIGLGPNVQAALA
MMAR_3959|M.marinum_M ------------------------MSEHESPTVMVVDDH---PIWRDAVA
MUL_3814|M.ulcerans_Agy99 ------------------------MSEHESPTVMVVDDH---PIWRDAVA
TH_3563|M.thermoresistible__bu ------------------------MGEPQQPTVMVVDDH---PIWREAVA
MAB_1522|M.abscessus_ATCC_1997 ------------------------MTDTEVG-VLLVDDQ---ELVRTGLR
MSMEG_0856|M.smegmatis_MC2_155 ----------------------------MAARILLADDH---ALVRSGLR
Mb0914c|M.bovis_AF2122/97 ARALADKAMLSTWLATSPVGATDIIAPAQQALAMAREVGDPAALVRALTA
MLBr_01753|M.leprae_Br4923 ARAVANKVMLHAILASSPPDGSDLVTQAQQALTMAREIGDSAVLARALTA
Rv0386|M.tuberculosis_H37Rv ARALADKALLDIFVDAAAG-----MEQAQQALVIAREVDEPALLSRALTA
: : :
Mflv_4288|M.gilvum_PYR-GCK YTFERFDGGGLPGGVGGDAIPIPMRVAQLADTAEVHHRTFGVDGAVAMAR
Mvan_2058|M.vanbaalenii_PYR-1 STFERYDGGGLPGGVGGDDIPLPMRVAQLADMVEVHHRAYGVDGAVAMAR
MAV_4201|M.avium_104 YTFERYDGGGLPTGARGEDIPIQMRIAQLADMVEVHHRSYGVAGAVAMVG
MMAR_3959|M.marinum_M RDLS-DDGFAVVATADGVATAQRRAAIVKPDVVVMDMRLADGDGVQATT-
MUL_3814|M.ulcerans_Agy99 RDLS-DDGFAVVATADGVATAQRRAAIVKPDVVVMDMRLADGDGVQATT-
TH_3563|M.thermoresistible__bu RDLA-EAGLSVVATADGVAAARRRAAAVRPDVVLMDMRLPDGDGARATA-
MAB_1522|M.abscessus_ATCC_1997 RILRRKDGFAIVGECADGSEVAAAVSRARPDVVIMDLRMKQMSGIEAIR-
MSMEG_0856|M.smegmatis_MC2_155 MIIDAEPDLQVVAEAADGYEALSALDTETVDLAILDIAMPRMTGLQAAR-
Mb0914c|M.bovis_AF2122/97 CGCSSG--YNAEAAAPYFAEATDLARAIDDKWTLCQILYWRGVGTCISGD
MLBr_01753|M.leprae_Br4923 CGFSSG--YDTEVARPYFAEAVELARTQGDKWTLSQIRLWGVVGFCVSGD
Rv0386|M.tuberculosis_H37Rv CGLIAVAVARADAAASYFAEAIDLARAVDDRWRLAQILTFQAVDAVVAGD
. .
Mflv_4288|M.gilvum_PYR-GCK SRSGGQFDPRVVDAFLADADAILEPPE--DAWSAALRE------------
Mvan_2058|M.vanbaalenii_PYR-1 SRRGGQFDPRVVDAFTADAVTVLSVPAPGDAWTVALRE------------
MAV_4201|M.avium_104 ARRGGQFDPGIADVFLRDADAILAGPQTGDAWAAALRE------------
MMAR_3959|M.marinum_M --------------------------------------------------
MUL_3814|M.ulcerans_Agy99 --------------------------------------------------
TH_3563|M.thermoresistible__bu --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0856|M.smegmatis_MC2_155 --------------------------------------------------
Mb0914c|M.bovis_AF2122/97 PNALRAAAEECRDLADTIGDRFVSRHCSLWLSLAQMWAGNLTEALELSRE
MLBr_01753|M.leprae_Br4923 PVALRAAAEAADDLAQEIGDRFVSLQCRLLLSIAQLWQGDMDGAIVRSGE
Rv0386|M.tuberculosis_H37Rv PVAARPAAQEARELAAAIGDHSNALWCRWCLGYAQLMRGELAAAAAQFGE
Mflv_4288|M.gilvum_PYR-GCK -----------------------APDYGTGLADGELDELLVALGDFVDLK
Mvan_2058|M.vanbaalenii_PYR-1 -----------------------APDYGERLHGAELDALLVALGDFVDLK
MAV_4201|M.avium_104 -----------------------APDR-HRVDEQSLDAALVALGDFVDLK
MMAR_3959|M.marinum_M -----------------------------EVLKVSPATRVLVLSASDERE
MUL_3814|M.ulcerans_Agy99 -----------------------------EVLKVSPATRVLVLSTSDERE
TH_3563|M.thermoresistible__bu -----------------------------EVRAVSPDSRVLVLSASEERD
MAB_1522|M.abscessus_ATCC_1997 -----------------------------LLHAAQ-GPPALALTTFDDDE
MSMEG_0856|M.smegmatis_MC2_155 -----------------------------EINRSHPDVRILILSMYDNEQ
Mb0914c|M.bovis_AF2122/97 ITAEAEASNDVPTKVLGLYTQAQVLAYCGASAAHAIAGACIAAATELGGV
MLBr_01753|M.leprae_Br4923 VVAGAEAAHDTVTRTFGLYVQTRALVHRDVSAALVTAGLVVEAAAELSGV
Rv0386|M.tuberculosis_H37Rv VVDEAEASQEVLHKANSLQGLAFALAYQGELSAARAAADAALEAAELGEY
Mflv_4288|M.gilvum_PYR-GCK CPFTLGHSRAVAELAAGAAALMGMD----------------------AGG
Mvan_2058|M.vanbaalenii_PYR-1 CPFTLGHSRAVAELAAGAAAVVGLD----------------------ADT
MAV_4201|M.avium_104 CPFTLGHSRAVARLAGQAARAAGLD----------------------ADA
MMAR_3959|M.marinum_M D--------VLEAVKAGATGYLVKS----------------------ASK
MUL_3814|M.ulcerans_Agy99 D--------VLEAVKTGATGYLVKS----------------------ASK
TH_3563|M.thermoresistible__bu D--------VLEAVKAGATGYLVKS----------------------ASK
MAB_1522|M.abscessus_ATCC_1997 L--------LSGALRAGAAGFILKD----------------------SPA
MSMEG_0856|M.smegmatis_MC2_155 Y--------FFEALKAGASGYVLKS----------------------VAD
Mb0914c|M.bovis_AF2122/97 YQGIGYAAMTYAALAAGDVTAALEASDAARPILRAQPDQ-VTMHQVLMAQ
MLBr_01753|M.leprae_Br4923 YQGIGYAAMVFAALAMGDVAAAVEASEACRPHLGADHGL-VAIHLELMAA
Rv0386|M.tuberculosis_H37Rv FAGMGYSALTTAALAAGDVQTAQHASEAAWRNLSLALPLSAAVQRAFNAQ
:
Mflv_4288|M.gilvum_PYR-GCK VDLLRRAGHVHDVGRIGVSNQVWSKPSTLTTGEMERVRLHPYLTVRILSQ
Mvan_2058|M.vanbaalenii_PYR-1 VTVVRRAGHLHDLGRIGVSNQIWSKPSSLTARELERVRLHPYLTVRILSQ
MAV_4201|M.avium_104 VALTRRAGHVHDLGRIGVSNQIWSRPGPLSGSQFERVRLHPYLTVRILDQ
MMAR_3959|M.marinum_M AELADAVRATAAG----------------------RAVFTPSLAGLVLGE
MUL_3814|M.ulcerans_Agy99 AELADAVRATAAG----------------------RAVFTPSLAGLVLGE
TH_3563|M.thermoresistible__bu TELVDAVHATAQG----------------------RAVFTPGLAGLVLGE
MAB_1522|M.abscessus_ATCC_1997 EELVRAVHAVARG----------------------EAYLDPAVTSRVLNA
MSMEG_0856|M.smegmatis_MC2_155 RDLLEACRATLRG---------------------EPFLYAGAITALIRDF
Mb0914c|M.bovis_AF2122/97 LALAGGDAIAARQFANDAVDATNGWHRMVALTIRARVATARGEPELARDD
MLBr_01753|M.leprae_Br4923 VALARGDVIVARRLADNSVSATTGWHQMAALTTRARIAMAQGEPELARAD
Rv0386|M.tuberculosis_H37Rv AALAGGDLSAARRWCDDAVQSMTGHHLAMALATRARIAVAEGKREEAERD
:
Mflv_4288|M.gilvum_PYR-GCK VGGLDAVARVAGNHHECLDGSGYPRGLPAAALSVPDRVLAAAVAYRSAVE
Mvan_2058|M.vanbaalenii_PYR-1 VGGLDAVAQVAGNHHEYLDGSGYPRGLPAAALSLPDRLLAAAVAYQSALE
MAV_4201|M.avium_104 VPGLRRLAEVAGNHHECLDGSGYPRGLAGSALGMPDRILAAAVCYQSGRE
MMAR_3959|M.marinum_M YRRIAQTADSS---------------------------------------
MUL_3814|M.ulcerans_Agy99 YRRIAQTADSS---------------------------------------
TH_3563|M.thermoresistible__bu YRRISRQPGAG---------------------------------------
MAB_1522|M.abscessus_ATCC_1997 YRRAP-AAVSG---------------------------------------
MSMEG_0856|M.smegmatis_MC2_155 LHRARQGGEPP---------------------------------------
Mb0914c|M.bovis_AF2122/97 AHAALACGAELHIYQGMPDAMELLAGLAGEVGSHSEGVRLLGAAAALRQQ
MLBr_01753|M.leprae_Br4923 IHAALACGADIQASLGISDSMELLAELISQGDNHRQAGRLFGAASAQREK
Rv0386|M.tuberculosis_H37Rv AHKALACAAESGAHLDLPDVLECLAGLASDAGTHHAAARLFGAAEAIRQQ
Mflv_4288|M.gilvum_PYR-GCK P------------RPYRVALSPAAAATRLRDRVREGHLDELAVDAVLSAA
Mvan_2058|M.vanbaalenii_PYR-1 P------------RPYRDPLPATSAAARLRERVREGRLDEVAVEAVLQAA
MAV_4201|M.avium_104 P------------RPYREQLSEAEAARRLRGRVRCGELDPVAAEAVLHAA
MMAR_3959|M.marinum_M --------------------------------------------------
MUL_3814|M.ulcerans_Agy99 --------------------------------------------------
TH_3563|M.thermoresistible__bu --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0856|M.smegmatis_MC2_155 --------------------------------------------------
Mb0914c|M.bovis_AF2122/97 TRQVRFKIWDAGYQASVTALREAMGDEDFDRAWAEGAALSTDEAIAYAQR
MLBr_01753|M.leprae_Br4923 TGEVRFKVWDAGYESAVAVLRGAMGCKDFDSAWAEGAAMPIDDAITYAQR
Rv0386|M.tuberculosis_H37Rv IGSVRFAIYRSDYVQSVTALRDAMGEKDFDAAWAEGAALSIKETIAYAQR
Mflv_4288|M.gilvum_PYR-GCK GHAAR-RVSARPGGLTPREIEVLCLVARGASNKEIAATLGISGKTARNHV
Mvan_2058|M.vanbaalenii_PYR-1 GHRAR-GHSPRPGGLTPREIEVLCLVARGASNKEIAATLGISGKTARNHV
MAV_4201|M.avium_104 GQPVGPRPNPRPDGLTPREIEVLGHVARGASNKEIAAALVISEKTARNHV
MMAR_3959|M.marinum_M ---------QDRPSLTERETEILRYVAKGLSAKQIAEKLSLSHRTVENHV
MUL_3814|M.ulcerans_Agy99 ---------QDRPSLTERETEILRYVAKGLSAKQIAEKLSLSHRTVENHV
TH_3563|M.thermoresistible__bu ---------PDAPRLTERETEILRYVAKGLTAKQIAAQLSLSHRTVENHV
MAB_1522|M.abscessus_ATCC_1997 ---------DAQDKLTARELDVLALIASGATNSEIAEQLVISEVTVKSHI
MSMEG_0856|M.smegmatis_MC2_155 -----------DSILTPREEEVLKLIAEGYSTREIAATLTISAKTVDRHR
Mb0914c|M.bovis_AF2122/97 GRGERKRPARGWGSLTPTERDVVRLVSEGLSNKDIAKRLFVSPRTVQTHL
MLBr_01753|M.leprae_Br4923 GRGNRKRPTTGWESLTPAEHNVIRLVSEGLDTKDIAARLFVSVRTVHTHL
Rv0386|M.tuberculosis_H37Rv GHSWRKRPATGWESLTPTEIDVVRLVGEGLANKDIATRLFVSPRTVQTHL
** * ::: :. * :** * :* *. *
Mflv_4288|M.gilvum_PYR-GCK ERTYAKIGATNRIGASMFALGHGLITPA----
Mvan_2058|M.vanbaalenii_PYR-1 ERTYAKIGATNRIGASMFALNHGLVAPA----
MAV_4201|M.avium_104 ERTYAKIGVSNRIGASMYALQHGLVPAAPPHS
MMAR_3959|M.marinum_M QATFRKLQVANRVELTRYAIEHGLDK------
MUL_3814|M.ulcerans_Agy99 QATFRKLQLANRVELTRYAIEHGLDK------
TH_3563|M.thermoresistible__bu QATFRKLQVANRVELARYAIEHGLDE------
MAB_1522|M.abscessus_ATCC_1997 GRIFVKLDLRDRAAAIVYAYDHGIVTPK----
MSMEG_0856|M.smegmatis_MC2_155 TNILAKLGLRDRLALTRYAIRAGLIEP-----
Mb0914c|M.bovis_AF2122/97 THVYAKLGLASRVQLVDEAARRGSPS------
MLBr_01753|M.leprae_Br4923 TRIYSKLGLTSRVQLVQEAARHN---------
Rv0386|M.tuberculosis_H37Rv THVYTKLGFTSRLQLAQAAARRT---------
*: .* *