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TDGVIAALLVDDQELVRSGLRRILRRKDGIAVVGECADGDEVPAAVAAYRPDVVVMDLRMKRVNGIEATR RLTAAGGPPVLALTTFSDEELLSGVLRAGASGFVLKDSPAEELIRAVRAVARGDGFLDPSVTARVLDTYR TAAEEPVPEAVDDLTPRELDVLRLMAKGRSNSEIADELVISGVTVKSHIGRIFLKLRLRDRAAAIVYAYQ KGIVAPRA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5522 | - | - | 100% (219) | two component LuxR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5474 | - | 2e-35 | 39.72% (214) | two component LuxR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1358 | - | 3e-31 | 37.04% (216) | two component LuxR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3157c | devR | 3e-30 | 38.35% (206) | two component transcriptional regulatory protein DevR |
| M. gilvum PYR-GCK | Mflv_5014 | - | 8e-30 | 33.80% (216) | two component LuxR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3133c | devR | 3e-30 | 38.35% (206) | two component transcriptional regulatory protein DevR |
| M. leprae Br4923 | MLBr_01286 | - | 2e-15 | 34.55% (110) | putative two-component response regulatory protein |
| M. abscessus ATCC 19977 | MAB_1522 | - | 3e-83 | 72.02% (218) | putative two-component system response regulator LuxR |
| M. marinum M | MMAR_1516 | devR | 5e-29 | 35.44% (206) | two-component transcriptional regulatory protein DevR |
| M. avium 104 | MAV_5280 | - | 5e-87 | 78.87% (213) | two-component system response regulator |
| M. smegmatis MC2 155 | MSMEG_6236 | - | 9e-36 | 39.73% (219) | two-component system, regulatory protein |
| M. thermoresistible (build 8) | TH_3184 | - | 6e-33 | 39.15% (212) | PUTATIVE two component transcriptional regulator, LuxR family |
| M. ulcerans Agy99 | MUL_2423 | devR | 3e-29 | 35.44% (206) | two component transcriptional regulatory protein DevR |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5522|M.vanbaalenii_PYR-1 ------MTDGV--IAALLVDDQELVRSGLRRILRRKDG-IAVVGECADGD
MAV_5280|M.avium_104 ------MTDPAPEITVLLVDDQDLVRSGLRRILRRKDG-FVIVAECADGD
MAB_1522|M.abscessus_ATCC_1997 ------MTDTE--VGVLLVDDQELVRTGLRRILRRKDG-FAIVGECADGS
Mb3157c|M.bovis_AF2122/97 ------------MVKVFLVDDHEVVRRGLVDLLGADPE-LDVVGEAGSVA
Rv3133c|M.tuberculosis_H37Rv ------------MVKVFLVDDHEVVRRGLVDLLGADPE-LDVVGEAGSVA
MMAR_1516|M.marinum_M ------------MVTVFLVDDHEVVRRGLIDLLDADPQ-LDVVGEAGSVS
MUL_2423|M.ulcerans_Agy99 ------------MVTVFLVDDHEVVRRGLIDLLDADPQ-LDVVGEAGSVS
MSMEG_6236|M.smegmatis_MC2_155 ------MTVTTREIRLALVDDHAILRQGLRSLLEREDD-LVVVGEASSEA
Mflv_5014|M.gilvum_PYR-GCK --------MSSEPVRIVLVDDHEMVIEGLKAMLAAFADRVCVVGQSVGAD
TH_3184|M.thermoresistible__bu ----MEPVAAPSPVRIVLVDDHEMVIEGLKAMLAAFEDRVCVVGHAVGAE
MLBr_01286|M.leprae_Br4923 MTGPTTDADAATPHRVLIAEDEALIRLDLAEMLR--DEGYDIVGEAADGQ
:.:*. :: .* :* :*... .
Mvan_5522|M.vanbaalenii_PYR-1 EVPAAVAAYRPDVVVMDLRMKRV---NGIEATRRLTAAGGPP-VLALTTF
MAV_5280|M.avium_104 EVPAAVAAHRPDVVVMDLRMRRV---DGIEATRRL--GGRPP-VLALTTF
MAB_1522|M.abscessus_ATCC_1997 EVAAAVSRARPDVVIMDLRMKQM---SGIEAIRLLHAAQGPP-ALALTTF
Mb3157c|M.bovis_AF2122/97 EAMARVPAARPDVAVLDVRLPDG---NGIELCRDLLSRMPDLRCLILTSY
Rv3133c|M.tuberculosis_H37Rv EAMARVPAARPDVAVLDVRLPDG---NGIELCRDLLSRMPDLRCLILTSY
MMAR_1516|M.marinum_M EAMARIPAANPDVAVLDVRLPDG---DGIELCRDLLSRMPNLRCLILTSY
MUL_2423|M.ulcerans_Agy99 EAMARIPAANPDVAVLDVRLPDG---DGIELCRDLLSRMPNLRCLILTSY
MSMEG_6236|M.smegmatis_MC2_155 EAEAMVAAVEPDVVLLDLKLSAGSDFEGLSLCAKLSAAHPDLGLLVLTTF
Mflv_5014|M.gilvum_PYR-GCK QVMGVVTDLDPDIVLCDVRMQGS---SGLDVCQQLRRRDPDRKIVMLSVY
TH_3184|M.thermoresistible__bu RAVEVVAELDPDIVLCDVRMQNT---SGLDLCLTLREQAPHRKVVMLSVY
MLBr_01286|M.leprae_Br4923 EAVELAERHKPDLVIMDVKMPRR---DGIDAASEIASKRIAP-IVVLTAF
.. **:.: *::: .*:. : : *: :
Mvan_5522|M.vanbaalenii_PYR-1 SDEELLSGVLRAGASGFVLKDSPAEELIRAVRAVARGDGFLDPSVTARVL
MAV_5280|M.avium_104 NEDELLSGALRAGAAGFVLKDSSAEELIRAVRAVARGEGYLDPAVTSRVL
MAB_1522|M.abscessus_ATCC_1997 DDDELLSGALRAGAAGFILKDSPAEELVRAVHAVARGEAYLDPAVTSRVL
Mb3157c|M.bovis_AF2122/97 TSDEAMLDAILAGASGYVVKDIKGMELARAVKDVGAGRSLLDNRAAAALM
Rv3133c|M.tuberculosis_H37Rv TSDEAMLDAILAGASGYVVKDIKGMELARAVKDVGAGRSLLDNRAAAALM
MMAR_1516|M.marinum_M TSDEAMLDAILAGASGYVVKDIKGMELARAIKEVGAGRSLLDNRAAAALM
MUL_2423|M.ulcerans_Agy99 TSDEAMLDAILAGASGYVVKDIKGMELARAIKEVGAGRSLLDNRAAAALM
MSMEG_6236|M.smegmatis_MC2_155 LDEDLVVRAVHAGARGYVVKDVDTTELVRAIRAISSGDSAFDSRSAAAVV
Mflv_5014|M.gilvum_PYR-GCK DDEQYLFQAMRVGASGYLLKSISSEDLVEQLESVHSGKTAIDPTMAARAV
TH_3184|M.thermoresistible__bu DDEQYLYQALRVGASGYLLKSISSDELVRQLEMVHRGQTALDPGMAARAV
MLBr_01286|M.leprae_Br4923 SQRDLVERARDAGAMAYLVKPFTISDLIPAIALAMSRFSELTALEREVAT
. : : . .** .:::* :* : :
Mvan_5522|M.vanbaalenii_PYR-1 DTYR-TAAEEPVPEAVDDLTPRELDVLRLMAKGRSNSEIADELVISGVTV
MAV_5280|M.avium_104 TTYR-KAAPGPHGAAIAELTTRERDVLTLIGKGLSNSEIADELCISGVTV
MAB_1522|M.abscessus_ATCC_1997 NAYR-RAPAAVSGDAQDKLTARELDVLALIASGATNSEIAEQLVISEVTV
Mb3157c|M.bovis_AF2122/97 AK---LRGAAEKQDPLSGLTDQERTLLGLLSEGLTNKQIADRMFLAEKTV
Rv3133c|M.tuberculosis_H37Rv AK---LRGAAEKQDPLSGLTDQERTLLGLLSEGLTNKQIADRMFLAEKTV
MMAR_1516|M.marinum_M SR---LRGVVERPDPLSGLTDQERTLLGLLSEGLTNKQIADRMFLAEKTV
MUL_2423|M.ulcerans_Agy99 SR---LRGVVERPDPLSGLTDQERTLLGLLSEGLTNKQIADRMFLAEKTV
MSMEG_6236|M.smegmatis_MC2_155 RS---LSGRTE---PREQLTDREIEVLRLLAAGLSNNKIGEKLFISATTA
Mflv_5014|M.gilvum_PYR-GCK E----------WPGARQGLTQRESEILALVVNGLSNRAIAAKLIIGDETV
TH_3184|M.thermoresistible__bu DTAARLQRDEFWPGARHGLTQRESEILSYVVNGLSNRGIAAKLVIGDETV
MLBr_01286|M.leprae_Br4923 LADR---------LETRKLVERAKGLLQVKQG------------MTEPEA
*. : :* : .
Mvan_5522|M.vanbaalenii_PYR-1 KSHIGRIFLKLRLRDR--AAAIVYAYQKGIVAPRA-
MAV_5280|M.avium_104 KSHIGRIFGKLDLRDR--AAAIVYAYDNGIVAPR--
MAB_1522|M.abscessus_ATCC_1997 KSHIGRIFVKLDLRDR--AAAIVYAYDHGIVTPK--
Mb3157c|M.bovis_AF2122/97 KNYVSRLLAKLGMERRTQAAVFATELKRSRPPGDGP
Rv3133c|M.tuberculosis_H37Rv KNYVSRLLAKLGMERRTQAAVFATELKRSRPPGDGP
MMAR_1516|M.marinum_M KNYVSRLLAKLGMERRTQAAVFAAELKRARSAGHR-
MUL_2423|M.ulcerans_Agy99 KNYVSRLLAKLGMERRTQAAVFAAELKRARSAGHR-
MSMEG_6236|M.smegmatis_MC2_155 KFHVSNIMRKLDVSRR-AEAVYAAS-KRGLI-----
Mflv_5014|M.gilvum_PYR-GCK KTHLSSIYRKLGVSDR--TAAVATALREGIFQ----
TH_3184|M.thermoresistible__bu KSHLRSIYRKLGVSDR--AAAVATALREGIYQ----
MLBr_01286|M.leprae_Br4923 FKWIQRAAMDRRTTMKRVAEVVLETLDTPKDT----
: . : .