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M. vanbaalenii PYR-1 Mvan_3766 (-)

annotation: response regulator receiver protein
coordinates: 4007562 - 4009181
length: 539

LTDTQIDLLSAARTAHQRRDWAASYEAFELASRYAPLRTDDLEAFAFASWRLGHIKESSRAAERVFAELT
RTDPNAAAMKANELALAWLVRGDINIGQGWMSRARRLLAAAEESQAHGYLIYLDAVVAAISQDLDALAGH
VRSLRETSERLDVPAVTALGLIAAGIEAILHARTAEGYALIDEAILPLMADQVPIEWAGDIYCMVLHHCH
KLADLPRMRSWTQSMEQWCGLSGSVPYGGVCDVHRLQVQVASTDLRGLEDRLGTASRALVEVNAWAAAEG
YYQLGEVRRLKGDLDGAATAFEQARALGLDPQPGEALLACRRGDNAAAWTSIRLALAGGDRLARVRLLRA
AVEIALGRDALSEAENYCRELEADAKAFGTPGFRAWAAHARGAVAVRRGDFGVALESLQSALREYRVQQS
RYETAEVYEWMALAKRGLGDREGAVADAATADAIYVQLGVEPAGICGAPTPGGLTRRELDVLTRIARGAT
NRQVAEQLHLSDKTVSRHLANIYAKLGVSTRTAAANWAFQQGVLTDER*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_3766--100% (539)response regulator receiver protein
M. vanbaalenii PYR-1Mvan_5928-7e-1326.73% (333) regulatory protein, LuxR
M. vanbaalenii PYR-1Mvan_2058-3e-1238.30% (94) metal dependent phosphohydrolase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0393-6e-1124.72% (538) LuxR/UHPA family transcriptional regulator
M. gilvum PYR-GCKMflv_1351-8e-1532.96% (179) response regulator receiver protein
M. tuberculosis H37RvRv2488c-1e-1024.91% (546) LuxR family transcriptional regulator
M. leprae Br4923MLBr_01753-8e-0922.50% (551) putative transcriptional regulator
M. abscessus ATCC 19977MAB_1522-2e-1140.00% (95) putative two-component system response regulator LuxR
M. marinum MMMAR_2962-5e-1625.36% (560) transcriptional regulatory protein
M. avium 104MAV_4201-1e-1429.90% (291) transcriptional regulator, LuxR family protein
M. smegmatis MC2 155MSMEG_4339-0.059.13% (526) TPR repeat-containing protein
M. thermoresistible (build 8)TH_3184-4e-1045.90% (61) PUTATIVE two component transcriptional regulator, LuxR family
M. ulcerans Agy99MUL_0351narL3e-0843.28% (67) nitrate/nitrite response regulator protein NarL

CLUSTAL 2.0.9 multiple sequence alignment


Mb0393|M.bovis_AF2122/97            -----------------------------------------------MSK
Rv2488c|M.tuberculosis_H37Rv        MDRRPRDFEQSRRRCRCNALRAGSMLASMSKIHPGVDVVPVDWSADGVSE
MMAR_2962|M.marinum_M               -----------------------------------------------MDE
MLBr_01753|M.leprae_Br4923          ----------------MYSLGEMQKPVPVGADYLASCLVARLRSTDVPTD
Mvan_3766|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4339|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3184|M.thermoresistible__bu      --------------------------------------------------
MUL_0351|M.ulcerans_Agy99           --------------------------------------------------
Mflv_1351|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_4201|M.avium_104                --------------------------------------------------
                                                                                      

Mb0393|M.bovis_AF2122/97            LLPRGTVTLLLADVEGSTWLWETHPDDMGAAVARLDKAVSGVIAAHDGVR
Rv2488c|M.tuberculosis_H37Rv        LVPTGTVTLLLADIEGATHLPGSQLDTT--AIAKLDRTLTELVREHRGVC
MMAR_2962|M.marinum_M               LLLTDTVTLLSADIEDSARLRQTQPTELSAALERLDQILTDAVSAYGGVR
MLBr_01753|M.leprae_Br4923          LHRGCTVTLFLGDVEGLAELSETQPDEAADAIARLDCVVSEAVAAHGGVQ
Mvan_3766|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4339|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3184|M.thermoresistible__bu      --------------------------------------------------
MUL_0351|M.ulcerans_Agy99           --------------------------------------------------
Mflv_1351|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_4201|M.avium_104                --------------------------------------------------
                                                                                      

Mb0393|M.bovis_AF2122/97            PVEQGEGDSFVLAFACASDAVAAALDLQRARLAPIRLRIGVHTGEVALR-
Rv2488c|M.tuberculosis_H37Rv        PVEQGEGDSFLVAFARASDAVACALGLQRAPLAPIRLRIGMHTGEVSSP-
MMAR_2962|M.marinum_M               AVEQSPGESLVVAFGRAQDAVECALQLQQAPLAPIRLCIGIHTGEVAQPR
MLBr_01753|M.leprae_Br4923          QVVQGVRGNFLATFARASDATACALDLQLAPIVPVRFRIALHTGEVQISN
Mvan_3766|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4339|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3184|M.thermoresistible__bu      --------------------------------------------------
MUL_0351|M.ulcerans_Agy99           --------------------------------------------------
Mflv_1351|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_4201|M.avium_104                --------------------------------------------------
                                                                                      

Mb0393|M.bovis_AF2122/97            DEGNYAGPTINRTARLRDLAHGGQTVLSGVTESLVIDRLPDKAWLVDLGT
Rv2488c|M.tuberculosis_H37Rv        DEGNCVGPTIDRTARLRELAHGGQTVLSGTTSDLVADLLPKDAWLNDLGT
MMAR_2962|M.marinum_M               DDGTYVGPTIDRTARLRDLARGGQTLLSAATKDIVINQLPEQAWLTDRGL
MLBr_01753|M.leprae_Br4923          DDVNNVVFMMVQAAGLLDLACGGQTVLSSITGDLVVDGLPADTWLVDLGS
Mvan_3766|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4339|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3184|M.thermoresistible__bu      --------------------------------------------------
MUL_0351|M.ulcerans_Agy99           --------------------------------------------------
Mflv_1351|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_4201|M.avium_104                --------------------------------------------------
                                                                                      

Mb0393|M.bovis_AF2122/97            HALRDLSRPERVMQLCHPELRIDFPPLRVANDDVAHGLPVHLTRFVGRGA
Rv2488c|M.tuberculosis_H37Rv        YRLDDLPRPERVVQLCHPDLHNAFPPLRTRKVVGAHCLPAQLTRLVGRVD
MMAR_2962|M.marinum_M               APLRDLIHFERVAQLCHPNLRNEFPPLCVTKSPAASGLPVHLTSFVGRGR
MLBr_01753|M.leprae_Br4923          HLLRDLARPVRVMQLCHRNLRRNLHELGIRTVPGGPSLPVPLTTFVGRAA
Mvan_3766|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4339|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3184|M.thermoresistible__bu      --------------------------------------------------
MUL_0351|M.ulcerans_Agy99           --------------------------------------------------
Mflv_1351|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_4201|M.avium_104                --------------------------------------------------
                                                                                      

Mb0393|M.bovis_AF2122/97            QITEVHRLVTDNRLVTLTGAGGVGKTRLAAQLAAQIAGEFGR-AWFVDLA
Rv2488c|M.tuberculosis_H37Rv        EVAQVRGLLDVKRWVTLTGVGGVGKTRLATQVASAVADGYPDGVWYVNLA
MMAR_2962|M.marinum_M               ELAEVHGLVVENRLVTLIGSGGVGKSRLAEQVVAQLAAQFVDGVRYVDLG
MLBr_01753|M.leprae_Br4923          QIKELQELLTEKRLLTLVGPGGVGKTRLALQVVARVADEFSGELSYFDLA
Mvan_3766|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4339|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3184|M.thermoresistible__bu      --------------------------------------------------
MUL_0351|M.ulcerans_Agy99           --------------------------------------------------
Mflv_1351|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_4201|M.avium_104                --------------------------------------------------
                                                                                      

Mb0393|M.bovis_AF2122/97            PITDPDLVPVTVAGALGLHDQPGRSTTDTVLRFLGGRPALVVLDNCEHLL
Rv2488c|M.tuberculosis_H37Rv        PITDPALVPIAAARVLGLPDQPGRSTVDTIVRRIGDRRMLVVLDNCEHLL
MMAR_2962|M.marinum_M               SITDPAVAPITMARALGLPNQPGRSAMDTLLHHLGDRQMLLLVDNCEHLL
MLBr_01753|M.leprae_Br4923          PDTDHDIFPITVL--------------DNLRRCIGDRRMLMVLDNCEYLL
Mvan_3766|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4339|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3184|M.thermoresistible__bu      --------------------------------------------------
MUL_0351|M.ulcerans_Agy99           --------------------------------------------------
Mflv_1351|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_4201|M.avium_104                --------------------------------------------------
                                                                                      

Mb0393|M.bovis_AF2122/97            DATAALVLALVKACRGVRLLATCREPLRVEGEVSYRVPSLSLSDEAVEMF
Rv2488c|M.tuberculosis_H37Rv        DGCAALIVALLGACPALRVLATSREPIAVAGEQIWRVPPLGHG-EAIELF
MMAR_2962|M.marinum_M               DASAPRLGAMLRDCPGLRLLVTSREPIKVAGEVTWRVPPLAVG-DAIALF
MLBr_01753|M.leprae_Br4923          DVCANVMTTLLGACPSLTILATSREPIGVAGEVIWRVSMLSPADEAVELF
Mvan_3766|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4339|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3184|M.thermoresistible__bu      --------------------------------------------------
MUL_0351|M.ulcerans_Agy99           --------------------------------------------------
Mflv_1351|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_4201|M.avium_104                --------------------------------------------------
                                                                                      

Mb0393|M.bovis_AF2122/97            CYRAQRVRPDFRLTDDNSAAVTEICKRLDGLPLAIELAAARLRSMTLDEI
Rv2488c|M.tuberculosis_H37Rv        TDRAREARPELEITADNLALVTEICHRLDGIPLAIELAASRVRALALTEI
MMAR_2962|M.marinum_M               TDRARLAQPDFALTDDNAGTVSQICRRLDTQPLGIELAAARVRTLSLAEI
MLBr_01753|M.leprae_Br4923          TERAALVQPGFSVTDGNRQIVTEICQRLDGMPLAIELAAARIRTLSLTEI
Mvan_3766|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4339|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3184|M.thermoresistible__bu      --------------------------------------------------
MUL_0351|M.ulcerans_Agy99           --------------------------------------------------
Mflv_1351|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_4201|M.avium_104                --------------------------------------------------
                                                                                      

Mb0393|M.bovis_AF2122/97            IDGLRDRFALLTGGARTAAHRQQTLWASVDWSYTLLTEPERTLFRRLAVF
Rv2488c|M.tuberculosis_H37Rv        VDSLHDRFRLLTGGSRIAVRRQQTMRASVDWSHALLTGPEQVLFRRLAVF
MMAR_2962|M.marinum_M               SAGLDDKIRLLTGGARTAVPRQQTLRASLEWSHGLLTDTERVLFRRLGVF
MLBr_01753|M.leprae_Br4923          ADGLDDRFRLLTGGARTAVRRQQTLRASMDWSYALLTESERALFRRLSAI
Mvan_3766|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4339|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3184|M.thermoresistible__bu      --------------------------------------------------
MUL_0351|M.ulcerans_Agy99           --------------------------------------------------
Mflv_1351|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_4201|M.avium_104                --------------------------------------------------
                                                                                      

Mb0393|M.bovis_AF2122/97            VGCFFVDDAQAVACSGDVQRYQVLDEITLLVDKSLVMADDNSGRTCYRLC
Rv2488c|M.tuberculosis_H37Rv        PSGFDLDGAQAAAAGGDVQRYEVVDLLSLLADKSLVVTDDSDGRTRYRLL
MMAR_2962|M.marinum_M               VGGFDLQAAQAVAAFGDVHPRDVLGDLSQLVDKSLVVADSSNGRTRYRRF
MLBr_01753|M.leprae_Br4923          SGTFDLKVAYAVGHDDLEEPDQVFDRLTMLIDKSLVIVEGRQGGSRYRLL
Mvan_3766|M.vanbaalenii_PYR-1       --------------------------------------MLTDT-------
MSMEG_4339|M.smegmatis_MC2_155      --------------------------------------MTTATGSVGRAS
MAB_1522|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3184|M.thermoresistible__bu      --------------------------------------------------
MUL_0351|M.ulcerans_Agy99           --------------------------------------------------
Mflv_1351|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_4201|M.avium_104                ----------------------------------MMLMAQAVLPTRAELL
                                                                                      

Mb0393|M.bovis_AF2122/97            ETMRHYALEKLSEAGEVDAVFARHRDYYTALAARVDNPGPSDYSHCLDQA
Rv2488c|M.tuberculosis_H37Rv        ETVRQYALEKLRESGDADAVRARHRDHYAAVAAGLDAPSVAGHERRLNQA
MMAR_2962|M.marinum_M               EGVGQLALEKLREAGEADIARARHCDHYTAVVAPLDLPARADYDFLLARV
MLBr_01753|M.leprae_Br4923          ETVRQYAMKKLEESNEVDLVLARHRDHYMALGALLDTPGDIDHEQLVEQV
Mvan_3766|M.vanbaalenii_PYR-1       QIDLLSAARTAHQRRDWAASYEAFELASRYAPLRTDDLEAFAFASWRLGH
MSMEG_4339|M.smegmatis_MC2_155      DHPALLEARAAHSRAEWAAAYQAYLRAEAIGPMTLDDLDAYATTAWRLGH
MAB_1522|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3184|M.thermoresistible__bu      --------------------------------------------------
MUL_0351|M.ulcerans_Agy99           --------------------------------------------------
Mflv_1351|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_4201|M.avium_104                AALSVAIDLGLGQPAEHMLRAALIATRLCDRLGLSRQQRDCVYYTTLVMW
                                                                                      

Mb0393|M.bovis_AF2122/97            ETEIDNLRAAFVWNRENSDTEGALALASSLLRVWMTRGRIQEGRAWFDSI
Rv2488c|M.tuberculosis_H37Rv        ELEIDNLRAAFAFSRENGDTGHALLLASCLQPLWRARGRLQEGLAWFAAA
MMAR_2962|M.marinum_M               EGELENLRAASAWLLESSDGESALMLASRLQPLWLVRGRISEGRSWFDAA
MLBr_01753|M.leprae_Br4923          ETELDNLRSAFAWSRETGDIAGALQLASSLQPIWFGRGHMYEGLAWFDSI
Mvan_3766|M.vanbaalenii_PYR-1       IKESSRAAERVFAELTRTDPNAAAMKANELALAWLVRGDINIGQGWMSRA
MSMEG_4339|M.smegmatis_MC2_155      SREAVRLAERVYGQLVRRDPATAATKAVDIALEWLTRGDLNIAQGWMNRA
MAB_1522|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3184|M.thermoresistible__bu      --------------------------------------------------
MUL_0351|M.ulcerans_Agy99           --------------------------------------------------
Mflv_1351|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_4201|M.avium_104                VGCHADSHEYARWFGDDIAVRHDSYLVDWSGIPYLRFLASNVGRGQPLAH
                                                                                      

Mb0393|M.bovis_AF2122/97            LADENARHLEVAAAVRARALADKALLDIFVDAAAG-----MEQAQQALVI
Rv2488c|M.tuberculosis_H37Rv        LADHDAHPAGADPGLYARALADRALIDAVAGITDR-----LDDAQKALAI
MMAR_2962|M.marinum_M               LAG--ASVLEVSPTVRARALADAAVLTMFVDVATS-----LESAAAALAI
MLBr_01753|M.leprae_Br4923          FEHKNIEHLVAPKEVLARAVANKVMLHAILASSPPDGSDLVTQAQQALTM
Mvan_3766|M.vanbaalenii_PYR-1       RRLLAAAEESQAHGYLIYLDAVVAAISQDLDALAG-------HVRSLRET
MSMEG_4339|M.smegmatis_MC2_155      RRLLTGAPTGPTHCYLAYLDVVLAVAEQDPEELAR-------RAEAVRHL
MAB_1522|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3184|M.thermoresistible__bu      --------------------------------------------------
MUL_0351|M.ulcerans_Agy99           --------------------------------------------------
Mflv_1351|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_4201|M.avium_104                RLSVMATLFANARGHISRLIHSHCASAALLADRIG----LGPNVQAALAY
                                                                                      

Mb0393|M.bovis_AF2122/97            AREVDEPALLSRALTACGLIAVAVARADAAASYFAEAIDLARAVDDRWRL
Rv2488c|M.tuberculosis_H37Rv        ARDIEDPALLARALTACG--GVAAYNADLARPWLAEAVGLARAVGDKWRL
MMAR_2962|M.marinum_M               ARELDDPASLVRALTACGLTASFSHHTEAVGQYFAEAASLAEELDDQWGL
MLBr_01753|M.leprae_Br4923          AREIGDSAVLARALTACG--FSSGYDTEVARPYFAEAVELARTQGDKWTL
Mvan_3766|M.vanbaalenii_PYR-1       SERLDVPAVTALGLIAAGIEAILHARTAEGYALIDEAILPLMADQVPIEW
MSMEG_4339|M.smegmatis_MC2_155      CDSVEDPALESLSLVSQAIAALHQGRVADGYALVDEALLPLLAGHVRVEW
MAB_1522|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3184|M.thermoresistible__bu      --------------------------------------------------
MUL_0351|M.ulcerans_Agy99           --------------------------------------------------
Mflv_1351|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_4201|M.avium_104                TFERYDGGGLPTGARGEDIPIQMRIAQLADMVEVHHRSYGVAGAVAMVGA
                                                                                      

Mb0393|M.bovis_AF2122/97            AQILTFQA-VDAVVAGDPVAARPAAQEARELAAAIGDHSNALWCRWCLGY
Rv2488c|M.tuberculosis_H37Rv        AEVLAWQAYVGFAGEGDPGATRAAGEEARSLADEIGDAFLSRSCRWALAA
MMAR_2962|M.marinum_M               SQILSWQS-NAAVVAGDAIAARRIGTEGRDLADAIGDRFNSWLCRLSLGY
MLBr_01753|M.leprae_Br4923          SQIRLWGV-VGFCVSGDPVALRAAAEAADDLAQEIGDRFVSLQCRLLLSI
Mvan_3766|M.vanbaalenii_PYR-1       AGDIYCMVLHHCHKLADLPRMRSWTQSMEQWCGLSGSVPYGGVCDVHRLQ
MSMEG_4339|M.smegmatis_MC2_155      AGDIYCVVLNLCHKLADHPRMRAWTQSMERWCDVHSASPFYRVCDVHRLQ
MAB_1522|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3184|M.thermoresistible__bu      --------------------------------------------------
MUL_0351|M.ulcerans_Agy99           --------------------------------------------------
Mflv_1351|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_4201|M.avium_104                RRGGQFDPGIADVFLRDADAILAGPQTGDAWAAALREAPDRHRVDEQSLD
                                                                                      

Mb0393|M.bovis_AF2122/97            AQLMRGELAAAAAQFGEVVDEAEASQEVLHKANSLQGLAFALAYQGELSA
Rv2488c|M.tuberculosis_H37Rv        ANLWQGNLEAAVGLSREVIGESDAAHDMVSSCAGQACLAHALAHRGDTEA
MMAR_2962|M.marinum_M               AQLWQGDLTGATTQFGALS-EAENLASLSS-----KGLGDALAYRGDVDA
MLBr_01753|M.leprae_Br4923          AQLWQGDMDGAIVRSGEVVAGAEAAHDTVTRTFGLYVQTRALVHR-DVSA
Mvan_3766|M.vanbaalenii_PYR-1       VQVASTDLRGLEDR-----------------------LGTASRALVEVNA
MSMEG_4339|M.smegmatis_MC2_155      LAAADDDYRRLEDQ-----------------------LFSASTALEDVNS
MAB_1522|M.abscessus_ATCC_1997      ------------------------------------------MTDTEVGV
TH_3184|M.thermoresistible__bu      --------------------------------------MEPVAAPSPVRI
MUL_0351|M.ulcerans_Agy99           ---------------------------------------MDVTKTEKVRV
Mflv_1351|M.gilvum_PYR-GCK          ---------------------------------------------MVLTG
MAV_4201|M.avium_104                AALVA--------------------------------LGDFVDLKCPFTL
                                                                                      

Mb0393|M.bovis_AF2122/97            ARAAADAALE-AAELGEYFAGMGYSALTTAALAAGDVQTAQHASEAAWRN
Rv2488c|M.tuberculosis_H37Rv        AAAAQASIDT-AVGLSPVLSGSACSALVFATLAAGDVAAAEHARESATR-
MMAR_2962|M.marinum_M               ARTAAEAALERAAESSEYTLGLGYSTVALAALAGGDVETARNASDLAWH-
MLBr_01753|M.leprae_Br4923          ALVTAGLVVEAAAELSGVYQGIGYAAMVFAALAMGDVAAAVEASEACRP-
Mvan_3766|M.vanbaalenii_PYR-1       WAAAEGYYQLGEVRR-------------LKGDLDGAATAFEQARALGLD-
MSMEG_4339|M.smegmatis_MC2_155      WVGAEGFYQLGEVRR-------------LRGDTEGALAAFAKARSLGKD-
MAB_1522|M.abscessus_ATCC_1997      LLVDDQELVRTGLRR-------------ILRR-KDGFAIVGECADGS---
TH_3184|M.thermoresistible__bu      VLVDDHEMVIEGLKA-------------MLAAFEDRVCVVGHAVGAE---
MUL_0351|M.ulcerans_Agy99           VVGDDHPLFREGVVR-------------ALSL-SGSVNVVGEADDGA---
Mflv_1351|M.gilvum_PYR-GCK          DLAAAEDFLRPHAQR---------------AKSRGHRSAQARLGWVRGR-
MAV_4201|M.avium_104                GHSRAVARLAGQAAR-------------AAGLDADAVALTRRAGHVHDLG
                                                                      .      .        

Mb0393|M.bovis_AF2122/97            LSLALPLSAAVQRAFNAQAALAGGDLSAARRWCDDAVQSMTGHHLAMALA
Rv2488c|M.tuberculosis_H37Rv        FFGASAAAIINDPTSSAQISCARGDLNAAHRLADGAASITRGVHRARALT
MMAR_2962|M.marinum_M               KLSVQPYAAMFWHSFRAEIALACGNVAGAKRCADEAVSVTTGWHRALALT
MLBr_01753|M.leprae_Br4923          HLGADHGLVAIHLELMAAVALARGDVIVARRLADNSVSATTGWHQMAALT
Mvan_3766|M.vanbaalenii_PYR-1       -------------PQPGEALLACRRGDNAAAWTSIRLALAGGDRLARVRL
MSMEG_4339|M.smegmatis_MC2_155      -------------PQPGEALLHCSVGQSRKAWTDLRVALAGAGPLDRMRL
MAB_1522|M.abscessus_ATCC_1997      -----------------EVAAAVSRARPDVVIMDLRMKQMSGIEA-IRLL
TH_3184|M.thermoresistible__bu      -----------------RAVEVVAELDPDIVLCDVRMQNTSGLDLCLTLR
MUL_0351|M.ulcerans_Agy99           -----------------AALELIETHLPDVALLDYRMPRMDGAQVAAAVR
Mflv_1351|M.gilvum_PYR-GCK          ------------------LLGARGDIASAREAFEQSLALLDGLPLRYETA
MAV_4201|M.avium_104                -----------RIGVSNQIWSRPGPLSGSQFERVRLHPYLTVRILDQVPG
                                                                                      

Mb0393|M.bovis_AF2122/97            TRARIAVAEGKREEAERDAHKALACAAESGAHLDLPDVLECLAGLASDAG
Rv2488c|M.tuberculosis_H37Rv        TRCRIEIAQGDRHRAERDAHDALGVAASIGAYLWVPDILECLASVMADAG
MMAR_2962|M.marinum_M               TRARVAMAEGEPEQAERAAYEALTCAADVGARTCLPDILECLGALAADQG
MLBr_01753|M.leprae_Br4923          TRARIAMAQGEPELARADIHAALACGADIQASLGISDSMELLAELISQGD
Mvan_3766|M.vanbaalenii_PYR-1       LRAAVEIALGRDALSEAENYCRELEADAKAFGTPGFRAWAAHARGAVAVR
MSMEG_4339|M.smegmatis_MC2_155      LRAAVVVALARDDIGEAQRYCDQLAAGAEAFATPGYRGWAAHARGAVLVR
MAB_1522|M.abscessus_ATCC_1997      HAAQGPPALALTTFDDDELLSGALRAGAAGFILK----------------
TH_3184|M.thermoresistible__bu      EQAPHRKVVMLSVYDDEQYLYQALRVGASGYLLK----------------
MUL_0351|M.ulcerans_Agy99           SNGLPTRVLLISAHDESAIVYQALQQGAAGFLLK----------------
Mflv_1351|M.gilvum_PYR-GCK          RVNFAYGQTLRRAGKRREADTVISAARELYVALG----------------
MAV_4201|M.avium_104                LRRLAEVAGNHHECLDGSGYPRGLAGSALGMPDRILAAAVCYQS------
                                                                                      

Mb0393|M.bovis_AF2122/97            THHAAARLFGAAEAIRQQIGSVRFAIYRSDYVQSVTALRDAMGEKDFAAA
Rv2488c|M.tuberculosis_H37Rv        SNREAVRLFGAADAARGRMGAVRFGIYQAGCNSSLATLRKSMGDSEFDDA
MMAR_2962|M.marinum_M               RDREAARVYGAAEGIRQRIGAMRFKIYDAGYQKSVAALHATMSTDEFDTA
MLBr_01753|M.leprae_Br4923          NHRQAGRLFGAASAQREKTGEVRFKVWDAGYESAVAVLRGAMGCKDFDSA
Mvan_3766|M.vanbaalenii_PYR-1       RGDFGVALESLQSALRE------YRVQQSRYETAEVYEWMALAKRGLGDR
MSMEG_4339|M.smegmatis_MC2_155      RGEFEAALDNLGAALRE------YRLQQERYDIAEVYEWMALAHRGLGDD
MAB_1522|M.abscessus_ATCC_1997      -----------------------------DSPAEELVRAVHAVARGE---
TH_3184|M.thermoresistible__bu      -----------------------------SISSDELVRQLEMVHRGQ---
MUL_0351|M.ulcerans_Agy99           -----------------------------DSTRTEIVKAVLDCAKGR---
Mflv_1351|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_4201|M.avium_104                ---------------------------GREPRPYREQLSEAEAARRLRGR
                                                                                      

Mb0393|M.bovis_AF2122/97            WAEGAALSIKETIAYAQRGHSWRKRPATGWESLTPTEIDVVRLVGEGLAN
Rv2488c|M.tuberculosis_H37Rv        WAEGTALSIDEAIAYAQRGRGARKRPTSGWGALTPTELEVALLVGEGLSN
MMAR_2962|M.marinum_M               WAHGAAFSAEEAIDYLQHRRGERKRATSGWAALTRAELNVVRLVGQGLSN
MLBr_01753|M.leprae_Br4923          WAEGAAMPIDDAITYAQRGRGNRKRPTTGWESLTPAEHNVIRLVSEGLDT
Mvan_3766|M.vanbaalenii_PYR-1       EGAVADAATADAIYVQLGVEPAGICGAPTPGGLTRRELDVLTRIARGATN
MSMEG_4339|M.smegmatis_MC2_155      TAADTDIATAENIYEQLAVQPSGVCGRASPGGLTRREIEVLRAIAGGATN
MAB_1522|M.abscessus_ATCC_1997      --AYLDPAVTSRVLN-AYRRAPAAVSGDAQDKLTARELDVLALIASGATN
TH_3184|M.thermoresistible__bu      --TALDPGMAARAVDTAARLQRDEFWPGARHGLTQRESEILSYVVNGLSN
MUL_0351|M.ulcerans_Agy99           --DVVAPSLVGGLAG-EIRQRAAPMAP----VLSAREREVLHRIAKGQSI
Mflv_1351|M.gilvum_PYR-GCK          ----ADTYVARCDRELKAGGLHQSRESRHTVELTPQEEAVSTLVSRGLSN
MAV_4201|M.avium_104                VRCGELDPVAAEAVLHAAGQPVGPRPNPRPDGLTPREIEVLGHVARGASN
                                                                    *:  *  :   :  *   

Mb0393|M.bovis_AF2122/97            KDIATRLFVSPRTVQTHLTHVYTKLGFTSRLQLAQAAARRT---------
Rv2488c|M.tuberculosis_H37Rv        KEIGVRLFISPRTVHSHLTHVYTKLGLSSRLQLAQQAARRGESERGPSRP
MMAR_2962|M.marinum_M               KDIAQRLFLSPRTVQTHLTHVYTKLGFNSRVQLAQQAAQHS---------
MLBr_01753|M.leprae_Br4923          KDIAARLFVSVRTVHTHLTRIYSKLGLTSRVQLVQEAARHN---------
Mvan_3766|M.vanbaalenii_PYR-1       RQVAEQLHLSDKTVSRHLANIYAKLGVSTRTAAANWAFQQGVLTDER---
MSMEG_4339|M.smegmatis_MC2_155      RQVAHQFVISDKTVGRHLANIYTKLGVSSRTAAVTWAYQNGVVRKDN---
MAB_1522|M.abscessus_ATCC_1997      SEIAEQLVISEVTVKSHIGRIFVKLDLRDRAAAIVYAYDHGIVTPK----
TH_3184|M.thermoresistible__bu      RGIAAKLVIGDETVKSHLRSIYRKLGVSDRAAAVATALREGIYQ------
MUL_0351|M.ulcerans_Agy99           PAIAGELYVAPSTVKTHVQRLYEKLGVSDRAAAVAEAMRQGLLD------
Mflv_1351|M.gilvum_PYR-GCK          REVAAELYVSPKTVQYHLTRIYAKLGIRSRSELAALRR------------
MAV_4201|M.avium_104                KEIAAALVISEKTARNHVERTYAKIGVSNRIGASMYALQHGLVPAAPPHS
                                      :.  : :.  *.  *:   : *:..  *