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ADGQKPAHIRFGEKSLMMETCLVSAPDRSSSLRERKKTQTRLAIRREAFRLFETQGYANTTIDQIAEAAE VSPRTFYRYFGVKEALLLSDDQRSPIVEAFAGAPRELTVAAAYRHAVEEVLGGLSAVERVDAIAGQRILY QVPEALNLVYTEYVALIDSIADVLRDRLEEDVDDLERRVIAGAVVGVVIAAAHNQPLPQESVSRALTILD TRMS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1157 | - | - | 100% (215) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1156 | - | 9e-67 | 64.58% (192) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0384 | - | 6e-47 | 52.49% (181) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3860c | - | 1e-06 | 47.27% (55) | transcriptional regulatory protein TetR-family |
| M. gilvum PYR-GCK | Mflv_3877 | - | 3e-65 | 64.95% (194) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3830c | - | 1e-06 | 47.27% (55) | transcriptional regulatory protein TetR-family |
| M. leprae Br4923 | MLBr_01070 | - | 1e-05 | 32.61% (138) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1379c | - | 5e-08 | 27.38% (168) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0222 | - | 9e-12 | 30.60% (183) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4894 | - | 2e-39 | 44.97% (189) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5673 | - | 4e-12 | 44.83% (87) | transcriptional regulator |
| M. thermoresistible (build 8) | TH_4253 | - | 1e-08 | 57.14% (42) | PUTATIVE transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_4892 | - | 1e-10 | 28.42% (183) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1157|M.vanbaalenii_PYR-1 ------MADGQKPAHIRFGE--KSLMMETCLVSAPDRSSSLRERKKTQTR
Mflv_3877|M.gilvum_PYR-GCK MPSLHSSADRPHSGQIRMPRPVQGVGCHTVPVTQSGETRGLRERKKAATR
MAV_4894|M.avium_104 -------------------------------MPASEAPPGLRERKKIKTR
MMAR_0222|M.marinum_M -------------------------------MSPPPAATSLAERKRTATR
MUL_4892|M.ulcerans_Agy99 -------------------------------MSPPPAATALAERKRTATR
Mb3860c|M.bovis_AF2122/97 ------------------------------------MVRPPQTARSERTR
Rv3830c|M.tuberculosis_H37Rv ------------------------------------MVRPPQTARSERTR
MSMEG_5673|M.smegmatis_MC2_155 -------------------------------MAYQTQQPGLRERKKQRTR
TH_4253|M.thermoresistible__bu --------------------------------------------------
MAB_1379c|M.abscessus_ATCC_199 ----------------------------------MPEQLSRFERRKQETR
MLBr_01070|M.leprae_Br4923 -------------------------MIVVGNFTQSNYVPASRGRRSSQLS
Mvan_1157|M.vanbaalenii_PYR-1 -----LAIRREAFRLFETQGYANTTIDQIAEAAEVSPRTFYRYFGVKE--
Mflv_3877|M.gilvum_PYR-GCK -----LAIRREAFRLFEDQGYANTTVEQIADAAEISPSTFYRYFAVKE--
MAV_4894|M.avium_104 -----QAIRREAFRLIEQNGYAATTVEQIAEAADVSPSTFFRYFGSKE--
MMAR_0222|M.marinum_M -----QRIATAAAQLVADLGLAAATVERIADTADISRATFFRYFNSKEDA
MUL_4892|M.ulcerans_Agy99 -----QRIATAAAQLVADLGLVAATVERIADTADISRATFFRYFNSKEDA
Mb3860c|M.bovis_AF2122/97 -----EALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKH-D
Rv3830c|M.tuberculosis_H37Rv -----EALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKH-D
MSMEG_5673|M.smegmatis_MC2_155 -----ATLISAAIDLCVRQGYEQTTVEQIAAAAEVSARTFSRYFATKD-A
TH_4253|M.thermoresistible__bu ------MLTDAAVELFLRHGYENTTVDQIAAVADVSPRTFSRYFATKD-A
MAB_1379c|M.abscessus_ATCC_199 -----REILGAALACFAERGYHATGIADIVRRVGIAQGTFYLYFQSKR-E
MLBr_01070|M.leprae_Br4923 GDDREQAILAVAERLLAERPLGDFSVDELAKGAGISRPTFYFYFPSKN-A
: * :. . :: ** :* *
Mvan_1157|M.vanbaalenii_PYR-1 -ALLLSDDQRSPIVEAFAGAPRELTVAAAYRHAVEEV---------LGGL
Mflv_3877|M.gilvum_PYR-GCK -AVLLSDDHTTPIVDAFVAAPSDMSPIAAYRHAVAEV---------FAGL
MAV_4894|M.avium_104 -SLLLADDLDPLILDALKAQPRELSLPQAFRRAYATV---------LSQL
MMAR_0222|M.marinum_M VAEGMTAHWLDRIATALAAQPEHLSAVEAVVGAFGGL---------AVGF
MUL_4892|M.ulcerans_Agy99 VAEGMTAHWLDRIATALAAQPEHQSAVEAVVGAFGGL---------AVGF
Mb3860c|M.bovis_AF2122/97 LLFADYDAGLHWFRAALDARPADESIIDSVQAAIFSFPYDVDAVTKIASL
Rv3830c|M.tuberculosis_H37Rv LLFADYDAGLHWFRAALDARPADESIIDSVQAAIFSFPYDVDAVTKIASL
MSMEG_5673|M.smegmatis_MC2_155 VMLAFLDDVVDLVAGELAQQPPELGELDAVFCAHITA------FEKTRVA
TH_4253|M.thermoresistible__bu VIVTLLDENLDQGARALREQPADMNHYDALFCAYRLF------YARTKDA
MAB_1379c|M.abscessus_ATCC_199 IVEQILDDLMERLSAALLDLPPSAPTSLAEYRDQAEHIS----TSLTGVL
MLBr_01070|M.leprae_Br4923 VLLSLLDDLNMKSRSAVEALAEQLPADPAAVWRSAIT--------AFFEV
. . :
Mvan_1157|M.vanbaalenii_PYR-1 SAVERVDAIAGQRILYQVPEALNLVYTEYVALIDSIADVLRDRLEE--DV
Mflv_3877|M.gilvum_PYR-GCK SPEERDNAILGQRLLYTVPDARGLVYNEYVRLLGLIADGLAHRLPE--PT
MAV_4894|M.avium_104 PDDQLEFESTRQRLMFSIPELKAAMYDEYYRTVTVAAEAIAHRIGR--AA
MMAR_0222|M.marinum_M AEMEDQVRELAT-LTRSSETLEAWTLHIYVRYESAIADLIAPRIPN--LV
MUL_4892|M.ulcerans_Agy99 AEMEDQVRELAT-LTRSSETLEAWTLHIYVRYESAIADLIAPRIPN--LV
Mb3860c|M.bovis_AF2122/97 RRGELEPSRIVRHMREVEADFADAIQAQLRRRNCDIAGAPDARLHI--AV
Rv3830c|M.tuberculosis_H37Rv RRGELEPSRIVRHMREVEADFADAIQAQLRRRNCDIAGAPDARLHI--AV
MSMEG_5673|M.smegmatis_MC2_155 MPGQLTDDRLLAAARIFTSS-PSLMQATMGFRPAPLFEVLAKRMGV--SA
TH_4253|M.thermoresistible__bu GPDDLTSDRVVAMTRIIMCS-PTLRQAVGEFRPHAVNVALAERMAV--DL
MAB_1379c|M.abscessus_ATCC_199 SADPQAARFLLLQAAAVDDDMAERVLAFYDAAAAIQATYLQHGISAGYFR
MLBr_01070|M.leprae_Br4923 CGTHRAVAVAGAAAKATSPEVRRLWSTVMQQWIDYNTAAIQAERKCGVAP
Mvan_1157|M.vanbaalenii_PYR-1 DDLERRVIAGAVVGVVIAAAHNQPLPQ-----ESVSRALTILDTRMS---
Mflv_3877|M.gilvum_PYR-GCK DAMERRVIAGAVVGVLIAASHNNPLPG-----DVVDRALTFLDSRLL---
MAV_4894|M.avium_104 DDFEVRVFAGALTGAMMAAFDSAPTTP-----ETIYRALDFMDAGMPLD-
MMAR_0222|M.marinum_M PQDPRPRLVGALAMAVVRIALDDWLGQG---GSLPDRVQQGLAAIVIA--
MUL_4892|M.ulcerans_Agy99 PQDPRPRLVGALAMAVVRIALDDWLGQG---GSLPDRVQQGLAAIVIA--
Mb3860c|M.bovis_AF2122/97 TARCVAAAVFGAMEAWMLGSDRSLGELARVCHVALESLRVGISDTWTTLT
Rv3830c|M.tuberculosis_H37Rv TARCVAAAVFGAMEAWMLGSDRSLGELARVCHVALESLRVGISDTWTTLT
MSMEG_5673|M.smegmatis_MC2_155 DDRKIALIAS-LWNAIMTTALVQLVPDVDWATVTVERIVNQMRTTYAEFL
TH_4253|M.thermoresistible__bu EDSRLRLVSS-VWDAIMWASQQDLGPHTDWDTVTVDNLIERMEHTYRQFV
MAB_1379c|M.abscessus_ATCC_199 SDLDAGHAARAVNGMLLASAFYSLRDPS---PAAFEQLAHAVREILYYGL
MLBr_01070|M.leprae_Br4923 DTIPAEDLAVALQLMTERVMAATFSDEKP--LIPDKKVIDTLVHIWLASI
:
Mvan_1157|M.vanbaalenii_PYR-1 ----------
Mflv_3877|M.gilvum_PYR-GCK ----------
MAV_4894|M.avium_104 ----------
MMAR_0222|M.marinum_M ----------
MUL_4892|M.ulcerans_Agy99 ----------
Mb3860c|M.bovis_AF2122/97 VSS-------
Rv3830c|M.tuberculosis_H37Rv VSS-------
MSMEG_5673|M.smegmatis_MC2_155 EVAGRRHEFA
TH_4253|M.thermoresistible__bu AQASAIGRPV
MAB_1379c|M.abscessus_ATCC_199 ASDHHPQIAD
MLBr_01070|M.leprae_Br4923 YGS-------