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TTGEQPSLRERKKTRTRETVRREAFRLFELNGYAQTTVDQIAEAADVSPRTFFRYFPTKESVLFSDDLLT PIIEAFLAAPAELSPVAAYRHAAAQVFAAMAGPDFDYVIARQRLLYALPEAKGALWNEHVKAIRVLTTAI AERLDRPEDDQVRVTAGAIIGVFMAASDDAPLDGEAFLQALDILETGLPE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0384 | - | - | 100% (191) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1156 | - | 3e-49 | 53.63% (179) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1157 | - | 5e-47 | 52.49% (181) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3860c | - | 1e-07 | 45.45% (55) | transcriptional regulatory protein TetR-family |
| M. gilvum PYR-GCK | Mflv_0350 | - | 5e-86 | 85.56% (187) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3830c | - | 1e-07 | 45.45% (55) | transcriptional regulatory protein TetR-family |
| M. leprae Br4923 | MLBr_02677 | - | 4e-05 | 28.57% (119) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4541 | - | 6e-09 | 25.61% (164) | TetR family transcriptional regulator |
| M. marinum M | MMAR_2812 | - | 4e-13 | 31.84% (201) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4894 | - | 1e-47 | 51.35% (185) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5673 | - | 3e-15 | 42.28% (123) | transcriptional regulator |
| M. thermoresistible (build 8) | TH_3524 | - | 2e-14 | 37.34% (158) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_2933 | - | 1e-12 | 31.84% (201) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0384|M.vanbaalenii_PYR-1 --MT--TGEQPSLRERKKTRTRETVRREAFRLFELNGYAQTTVDQIAEAA
Mflv_0350|M.gilvum_PYR-GCK --MEGMNPEQPGLRERKKTRTRETVRREAFRLFELNGYAQTTVDQIAEAA
MAV_4894|M.avium_104 --MP-ASEAPPGLRERKKIKTRQAIRREAFRLIEQNGYAATTVEQIAEAA
Mb3860c|M.bovis_AF2122/97 ------MVRPP--QTARSERTREALRQAALVRFLAQGVEATSAEQIAEDA
Rv3830c|M.tuberculosis_H37Rv ------MVRPP--QTARSERTREALRQAALVRFLAQGVEATSAEQIAEDA
MMAR_2812|M.marinum_M ------MTVPTNRHELRRRSTHEALRRAALKSFACKGFAQVTVTELAREA
MUL_2933|M.ulcerans_Agy99 ------MTVPTNRHELRRRSTHEALRRAALKSFARKGFAQVTVTELAREA
MSMEG_5673|M.smegmatis_MC2_155 ---MAYQTQQPGLRERKKQRTRATLISAAIDLCVRQGYEQTTVEQIAAAA
TH_3524|M.thermoresistible__bu ---------------VRGHRNREALIAAAIDLFTVNGYEQTTVEQIAEAA
MAB_4541|M.abscessus_ATCC_1997 MTNLIPESETPNKRERAKADRRDQLLRAAARLLAMRGYARVRLEDLGSAV
MLBr_02677|M.leprae_Br4923 ------MESQRRTQEERSTATRDALTLARHRLWRLRGYAEVGTPEIAKEA
: : .* . ::. .
Mvan_0384|M.vanbaalenii_PYR-1 DVSPRTFFRYFPTKESVLFSD--DLLTPIIEAFLAAPAELSPVAAYRHAA
Mflv_0350|M.gilvum_PYR-GCK FVSPRTFFRYFPTKESVLFSD--DLFNPIIEEFLAAPAELSPVAAYRHAA
MAV_4894|M.avium_104 DVSPSTFFRYFGSKESLLLAD--DLDPLILDALKAQPRELSLPQAFRRAY
Mb3860c|M.bovis_AF2122/97 GVSLRTFYRHFRSKHDLLFADYDAGLHWFRAALDARPADESIIDSVQAAI
Rv3830c|M.tuberculosis_H37Rv GVSLRTFYRHFRSKHDLLFADYDAGLHWFRAALDARPADESIIDSVQAAI
MMAR_2812|M.marinum_M GVTERTFFRHFPTKEAVLFQDYENQLEWLAQALAQRPVSEPLFDAVLASV
MUL_2933|M.ulcerans_Agy99 GVTERTFFRHFPTKEAVLFQDYENQLEWLARALAQRPVSEPLFDAVLASV
MSMEG_5673|M.smegmatis_MC2_155 EVSARTFSRYFATKDAVMLAFLDDVVDLVAGELAQQPPELGELDAVFCAH
TH_3524|M.thermoresistible__bu GVAPRTFFRHFAAKEDILFHGYADRLAEATRRFRAAR-SGSLWKALAEAS
MAB_4541|M.abscessus_ATCC_1997 GISGPAIYRHFPNKEALLVDLLTDVSRRLLEGGMTVAAAASSPAEALDGL
MLBr_02677|M.leprae_Br4923 DTTRGAVYHQFTDKAALFRDVVETVEQDAMAQIASVVASSGAKTPVDAIR
: :. : * * ::
Mvan_0384|M.vanbaalenii_PYR-1 AQVFAAMAGPDFDYVIAR-----QRLLYA--LPEAKGALWNEHVKAIRVL
Mflv_0350|M.gilvum_PYR-GCK ARVFETMAGSDYDYIIAR-----QRLLYD--LPEAKGALWNEHVGAIRRL
MAV_4894|M.avium_104 ATVLSQLPDDQLEFESTR-----QRLMFS--IPELKAAMYDEYYRTVTVA
Mb3860c|M.bovis_AF2122/97 FSFPYDVDAVTKIASLRRGELEPSRIVRH--MREVEADFADAIQAQLRRR
Rv3830c|M.tuberculosis_H37Rv FSFPYDVDAVTKIASLRRGELEPSRIVRH--MREVEADFADAIQAQLRRR
MMAR_2812|M.marinum_M AAFPHDLEVVRQAATARSELISADRIANH--LRVVQSSFAQVLTAFVRDR
MUL_2933|M.ulcerans_Agy99 AAFPHDLEVVRQAATARSELISADRIANH--LRVVQSSFAQVLTAFVRNR
MSMEG_5673|M.smegmatis_MC2_155 ITAFEKTRVAMPGQLTDDRLLAAARIFTS--SPSLMQATMGFRPAPLFEV
TH_3524|M.thermoresistible__bu EAVATAIAENPGIFLVRA------RMYGE--LPALRATMLRINDDWIDQM
MAB_4541|M.abscessus_ATCC_1997 IDFHLDFALNESDLIRVQ-----DRDLDS--LPENARRQVRQYQRRYVEA
MLBr_02677|M.leprae_Br4923 AKVDAWLEGLADPQVRQLILLYAPSVLGWAAFRDVAQHYSLGMTEQQLLS
Mvan_0384|M.vanbaalenii_PYR-1 TTAIAER-LDRPEDD-QVRVTAGAIIGVFMAASD------DAPLDGEAFL
Mflv_0350|M.gilvum_PYR-GCK TSAIAKR-LGRPEDDYQARVTAGAIIGVFMAASD------DEPMSGEAFL
MAV_4894|M.avium_104 AEAIAHR-IGRAADDFEVRVFAGALTGAMMAAFD------SAPTTPETIY
Mb3860c|M.bovis_AF2122/97 NCDIAGAPDARLHIAVTARCVAAAVFGAMEAWMLGSD--RSLGELARVCH
Rv3830c|M.tuberculosis_H37Rv NCDIAGAPDARLHIAVTARCVAAAVFGAMEAWMLGSD--RSLGELARVCH
MMAR_2812|M.marinum_M YADVA---NVDLVAEVAGATIAAALVVAVENWGR--N--GCAVDLGELVA
MUL_2933|M.ulcerans_Agy99 YADVA---NVDLVAEVAGATIAAALVVAVENWGR--Y--GCAEDLGELVA
MSMEG_5673|M.smegmatis_MC2_155 LAKRMGVSADDRKIALIASLWNAIMTTALVQLVPDVD--WATVTVERIVN
TH_3524|M.thermoresistible__bu TTEVARWLGSDAAVDVRPRLAATVINGANRTAIDLWVSADGKGDLVELMA
MAB_4541|M.abscessus_ATCC_1997 WVQVLCR-SQQGLDESDARIKAHAAFGLMNSTPYS----AGRSAPSQTRT
MLBr_02677|M.leprae_Br4923 EASRARQLAQPLDHVLIGKLYESAMAIRRHHRLPEAS--PARNQTGAAPT
Mvan_0384|M.vanbaalenii_PYR-1 QALDILETGLPE--------------------------------
Mflv_0350|M.gilvum_PYR-GCK EALDLLDQALPR--------------------------------
MAV_4894|M.avium_104 RALDFMDAGMPLD-------------------------------
Mb3860c|M.bovis_AF2122/97 VALESLRVGISDTWTTLTVSS-----------------------
Rv3830c|M.tuberculosis_H37Rv VALESLRVGISDTWTTLTVSS-----------------------
MMAR_2812|M.marinum_M ASLDLVRSGLAPLS------------------------------
MUL_2933|M.ulcerans_Agy99 ASLDLVRSGLAPLS------------------------------
MSMEG_5673|M.smegmatis_MC2_155 QMRTTYAEFLEVAGRRHEFA------------------------
TH_3524|M.thermoresistible__bu DAVRLVRPTLDRIERESRTVANPVRRRDVV--------------
MAB_4541|M.abscessus_ATCC_1997 VLRQMVVAALRS--------------------------------
MLBr_02677|M.leprae_Br4923 HREHVARPSCEALTRHIRHRSTRTRSHRGKRGELLPRAATSSLL