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AYQTQQPGLRERKKQRTRATLISAAIDLCVRQGYEQTTVEQIAAAAEVSARTFSRYFATKDAVMLAFLDD VVDLVAGELAQQPPELGELDAVFCAHITAFEKTRVAMPGQLTDDRLLAAARIFTSSPSLMQATMGFRPAP LFEVLAKRMGVSADDRKIALIASLWNAIMTTALVQLVPDVDWATVTVERIVNQMRTTYAEFLEVAGRRHE FA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5673 | - | - | 100% (213) | transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_1648 | - | 1e-09 | 30.59% (170) | putative transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_1420 | - | 7e-07 | 25.60% (168) | transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3860c | - | 3e-07 | 31.30% (115) | transcriptional regulatory protein TetR-family |
| M. gilvum PYR-GCK | Mflv_1728 | - | 3e-48 | 49.50% (200) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3830c | - | 3e-07 | 31.30% (115) | transcriptional regulatory protein TetR-family |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0248c | - | 3e-09 | 38.37% (86) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0222 | - | 2e-09 | 30.59% (170) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4894 | - | 4e-18 | 37.21% (172) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_4253 | - | 2e-43 | 46.49% (185) | PUTATIVE transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_2933 | - | 1e-09 | 30.95% (168) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5023 | - | 4e-47 | 49.50% (200) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_5673|M.smegmatis_MC2_155 --MAYQTQQPGLRERKKQRTRATLISAAIDLCVRQG-YEQTTVEQIAAAA
TH_4253|M.thermoresistible__bu ----------------------MLTDAAVELFLRHG-YENTTVDQIAAVA
Mflv_1728|M.gilvum_PYR-GCK MAEPRGEPVLGLRERKKRRTRATLIDAAMGLCDRQG-FDATTVDQIAAIA
Mvan_5023|M.vanbaalenii_PYR-1 -----------MRERKKRRTRATLIDAAVGLCDRQG-YDATTVDQIAHVA
Mb3860c|M.bovis_AF2122/97 -----MVRPP--QTARSERTREALRQAALVRFLAQG-VEATSAEQIAEDA
Rv3830c|M.tuberculosis_H37Rv -----MVRPP--QTARSERTREALRQAALVRFLAQG-VEATSAEQIAEDA
MUL_2933|M.ulcerans_Agy99 -----MTVPTNRHELRRRSTHEALRRAALKSFARKG-FAQVTVTELAREA
MAV_4894|M.avium_104 --MPASEAPPGLRERKKIKTRQAIRREAFRLIEQNG-YAATTVEQIAEAA
MMAR_0222|M.marinum_M --MSPPPAATSLAERKRTATRQRIATAAAQLVADLG-LAAATVERIADTA
MAB_0248c|M.abscessus_ATCC_199 -----MRPASGLREQKKSETKLALSRAALELALDRGDLAAVTVDDIADAV
: * * .:. :* .
MSMEG_5673|M.smegmatis_MC2_155 EVSARTFSRYFATK-DAVMLAFLDDVVDLVAGELAQQPPELGELDAVFCA
TH_4253|M.thermoresistible__bu DVSPRTFSRYFATK-DAVIVTLLDENLDQGARALREQPADMNHYDALFCA
Mflv_1728|M.gilvum_PYR-GCK EVSPRTFSRYFATK-DAIALALIDEVLDSAAAELARQPLDIGNFEALRRA
Mvan_5023|M.vanbaalenii_PYR-1 EVSPRTFSRYFATK-DAIALALIDEVLVHTAVELVRQPRYLPHMEALRRA
Mb3860c|M.bovis_AF2122/97 GVSLRTFYRHFRSK-HDLLFADYDAGLHWFRAALDARPADESIIDSVQAA
Rv3830c|M.tuberculosis_H37Rv GVSLRTFYRHFRSK-HDLLFADYDAGLHWFRAALDARPADESIIDSVQAA
MUL_2933|M.ulcerans_Agy99 GVTERTFFRHFPTK-EAVLFQDYENQLEWLARALAQRPVSEPLFDAVLAS
MAV_4894|M.avium_104 DVSPSTFFRYFGSK-ESLLLA--DDLDPLILDALKAQPRELSLPQAFRRA
MMAR_0222|M.marinum_M DISRATFFRYFNSKEDAVAEGMTAHWLDRIATALAAQPEHLSAVEAVVGA
MAB_0248c|M.abscessus_ATCC_199 RVSARTFRNYFTSK-EDAVLFSLRGIEDNAVALLRQRPQHEHVVDSLEAV
:: ** .:* :* . * :* ::.
MSMEG_5673|M.smegmatis_MC2_155 HITAFEKTRVAMPGQLTDDRLLAAARIFTSSPSLMQATMGFRPAPLFEVL
TH_4253|M.thermoresistible__bu YRLFYARTKDAGPDDLTSDRVVAMTRIIMCSPTLRQAVGEFRPHAVNVAL
Mflv_1728|M.gilvum_PYR-GCK YIAMARNTKLAAAGALTSERMLQILRIVMSSGTLRQATVEYRASKVDRLL
Mvan_5023|M.vanbaalenii_PYR-1 YVAMAEASKLAPPGALSAQRLLQILRIIVSSPTLRQAAVGYRAGPVDAVV
Mb3860c|M.bovis_AF2122/97 IFSFPYDVDAVTKIASLRRGELEPSRIVRHMREVEADFADAIQAQLRRRN
Rv3830c|M.tuberculosis_H37Rv IFSFPYDVDAVTKIASLRRGELEPSRIVRHMREVEADFADAIQAQLRRRN
MUL_2933|M.ulcerans_Agy99 VAAFPHDLEVVRQAATARSELISADRIANHLRVVQSSFAQVLTAFVRNRY
MAV_4894|M.avium_104 YATVLSQLPDDQLEFESTRQRLMFS--IPELKAAMYDEYYRTVTVAAEAI
MMAR_0222|M.marinum_M FGGLAVGFAEMEDQVRELATLTRSSETLEAWT--LHIYVRYESAIADLIA
MAB_0248c|M.abscessus_ATCC_199 MLDLATSEAFSTTVAVTR-----LSAQNPGLAAHDAARSEDVGTVVLTEV
MSMEG_5673|M.smegmatis_MC2_155 AKRMGVSADDRKIALIASLWNAIMTTALVQLVPDVDWATVTVERIVNQMR
TH_4253|M.thermoresistible__bu AERMAVDLEDSRLRLVSSVWDAIMWASQQDLGPHTDWDTVTVDNLIERME
Mflv_1728|M.gilvum_PYR-GCK AERMGTSVHDRRVKLLAAVWGAVLITAMDDLAR-KHVSGISVDDVISAFD
Mvan_5023|M.vanbaalenii_PYR-1 AERMGATVDDRRVKLVAAVWGVVLMTALQDVCR-SAVD-FGVDDVIAAVE
Mb3860c|M.bovis_AF2122/97 CDIAGAPDARLHIAVTARCVAAAVFGAMEAWMLGSDRSLGELARVCHVAL
Rv3830c|M.tuberculosis_H37Rv CDIAGAPDARLHIAVTARCVAAAVFGAMEAWMLGSDRSLGELARVCHVAL
MUL_2933|M.ulcerans_Agy99 ADVA---NVDLVAEVAGATIAAALVVAVENWGRYG--CAEDLGELVAASL
MAV_4894|M.avium_104 AHRIGRAADDFEVRVFAGALTGAMMAAFD--------SAPTTPETIYRAL
MMAR_0222|M.marinum_M PRIPNLVPQDPRPRLVGALAMAVVRIALDDWLG----QGGSLPDRVQQGL
MAB_0248c|M.abscessus_ATCC_199 SRRAGLDPDVDLYPRLVCNAAYAVLATVIQLAVSGSKLSKDPGALVAQGF
: :
MSMEG_5673|M.smegmatis_MC2_155 TTYAEFLEVAGRRHEFA-
TH_4253|M.thermoresistible__bu HTYRQFVAQASAIGRPV-
Mflv_1728|M.gilvum_PYR-GCK DTYAEFAGEIAGIGQPV-
Mvan_5023|M.vanbaalenii_PYR-1 ATYAEFAGEIAGVVQPV-
Mb3860c|M.bovis_AF2122/97 ESLRVGISDTWTTLTVSS
Rv3830c|M.tuberculosis_H37Rv ESLRVGISDTWTTLTVSS
MUL_2933|M.ulcerans_Agy99 DLVRSGLAPLS-------
MAV_4894|M.avium_104 DFMDAGMPLD--------
MMAR_0222|M.marinum_M AAIVIA------------
MAB_0248c|M.abscessus_ATCC_199 QRLRDGLA----------