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MRGTDATEHILDAAVVEFERHGFRRVALDDVARRAGVSRTTIYRRFANKDELVGAVIERENIQLFADIAA ELKTAGPQSNYYVEAFTLSILKFRRHRVLHQMIIDEPGLVLELAGRYHRAAIDRMAAALRVIFPPGFAER IGPAAVDELADCILRYAAMVLLLPSAQPLETADDVRAFARQHFLPSLPAALRTVPA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0855 | - | - | 100% (196) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_2232 | - | 2e-10 | 28.57% (196) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0969 | - | 5e-08 | 30.96% (197) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0710c | - | 1e-07 | 30.00% (120) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_0059 | - | 8e-90 | 85.28% (197) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1255c | - | 1e-07 | 24.50% (200) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_00316 | - | 8e-08 | 37.74% (106) | putative TetR/AcrR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3273c | - | 2e-19 | 35.98% (189) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0287 | - | 2e-19 | 35.60% (191) | transcriptional regulatory protein |
| M. avium 104 | MAV_5227 | - | 2e-18 | 35.60% (191) | TetR-family protein transcriptional regulator, putative |
| M. smegmatis MC2 155 | MSMEG_0962 | - | 9e-82 | 78.17% (197) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_2255 | - | 8e-79 | 76.04% (192) | TetR-family protein transcriptional regulator |
| M. ulcerans Agy99 | MUL_4837 | - | 5e-20 | 36.13% (191) | transcriptional regulatory protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0855|M.vanbaalenii_PYR-1 ------------------MR-GTD-ATEHILDAAVVEFERHGFRRVALDD
Mflv_0059|M.gilvum_PYR-GCK ------------------MS-GPDPASEQILDAAVVEFERHGFRRVALED
MSMEG_0962|M.smegmatis_MC2_155 ------------------MP-GPDAASRAILDAALVEFERYGFRRVALDD
TH_2255|M.thermoresistible__bu ------------------MPERPDPARQAILDAAVVEFEQHGFRKVALED
MMAR_0287|M.marinum_M ------MQSRMGTETSTDGVESITDLDRTILDTARAVFETYGVRRANIED
MUL_4837|M.ulcerans_Agy99 ----------MGTETSTDGVESITDLDRTILDTAHAVFETYGVRRANIED
MAV_5227|M.avium_104 ----------MQSHRADAAAGERTDLDRLILDTARGVFETYGVRRANIDD
MAB_3273c|M.abscessus_ATCC_199 ---MDLGLVWSQLSSGQSALGDEDEERERLLDAARVEFVAHGFRRAAVAD
Rv1255c|M.tuberculosis_H37Rv -----------MAGTDWLSARRTELAADRILDAAERLFTQRDPASIGMNE
MLBr_00316|M.leprae_Br4923 MSVPRSGLSVQMAQPARPLRADAARNRARILGVAYEAFATEGLS-VPIDE
Mb0710c|M.bovis_AF2122/97 ------------MPHESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDD
: ..* * . : :
Mvan_0855|M.vanbaalenii_PYR-1 VARRAGVSRTTIYRRFANKDELVGAVIE---RENIQLFADIAAELKTAGP
Mflv_0059|M.gilvum_PYR-GCK VARRAGVSRTTIYRRFANKDQLVGAVIE---RENVALFSDIATELKQAGP
MSMEG_0962|M.smegmatis_MC2_155 VARRAGVSRTTIYRRFANRDDLVGAVIE---RENVSLFADIAAELKDAKP
TH_2255|M.thermoresistible__bu VARRAGVSRTTIYRRFTNRDELVAAVVD---RENAALFADIAAELKHSGP
MMAR_0287|M.marinum_M VATRAGVSRSTIYRRFPTKDELFERVVR---REAELFFAALNQATNGHNP
MUL_4837|M.ulcerans_Agy99 VATRAGVSRSTIYRRFPTKDELFERVVR---REAELFFAALNQATNGHNP
MAV_5227|M.avium_104 VAARAGVSRSTIYRRFPTKKNLFGQVVR---REAELFFSTLDQATAGCDP
MAB_3273c|M.abscessus_ATCC_199 IAKRANVSRQTLNRRCGDKDDMVSAVVG---REVLQFFVTLAPLLDPKDN
Rv1255c|M.tuberculosis_H37Rv IAKAAGCSRATLYRYFDSREALRTAYVH---RETRRLGREIMVKIADVVE
MLBr_00316|M.leprae_Br4923 IARRAGVGAGTVYRHFPTKEALCAAVIG---DRMPHLVDDGYVLLKSAGP
Mb0710c|M.bovis_AF2122/97 IARAAGIARRTLFRYYASKNAIPWGDFSTHLAQLQGLLDNIDSRIQLRDA
:* *. . *: * :. : . . :
Mvan_0855|M.vanbaalenii_PYR-1 QSNYYVEAFTLSILKFRRHRVLHQMIIDEPGLVLELAGRYHRAAIDRMAA
Mflv_0059|M.gilvum_PYR-GCK QSNYYVEAFTLSILKFRGHRVLHRMITEEPGLVLELASLYYRAAIERMAE
MSMEG_0962|M.smegmatis_MC2_155 QSNIYVEAFTLSILRFRRHRVLNQMMKDEPALVLELAHRHYGAAIERMAA
TH_2255|M.thermoresistible__bu QGDYYVEAFTLAILKFRRHRVLHRMITDEPGFILHLAQQHWGAAVERMAE
MMAR_0287|M.marinum_M R-EAVIEAFTLGVRLIQDSPLYSRIAESEP-ELFGMFSRSHVFPIGQFAD
MUL_4837|M.ulcerans_Agy99 R-EAVIEAFTLGVRLIRDSPLYSRIAESEP-ELFGMFSRSHVFPIGQFAD
MAV_5227|M.avium_104 Q-QAVIEAFALGVRLVKNSALYSRIAESEP-ELFGLFSRSQVFPIRQFAD
MAB_3273c|M.abscessus_ATCC_199 VEDQVVELFVTGMRECRVNPVVAALKEYET---ESMSVGLFATEHGNYQA
Rv1255c|M.tuberculosis_H37Rv PAERLLVSITTTLRMVRDNPALAAWFTTTR-----PPIGGEMAGRSEVIA
MLBr_00316|M.leprae_Br4923 GEALFTYLRSLVLHWGATDRGLVDALAGAG-----------GIDILGVAP
Mb0710c|M.bovis_AF2122/97 LRAALLAFNTFDESETIRHRKRMRVILQTP---------ELQAYSMTMYA
Mvan_0855|M.vanbaalenii_PYR-1 ALRVIFPPGFAERIGPAAVDELADCILRYAAMVLLLPSAQPLETAD--DV
Mflv_0059|M.gilvum_PYR-GCK ALRVIFPPGFAERIGADAVDELADTILRYATMVLLLPSAQPLETAD--DI
MSMEG_0962|M.smegmatis_MC2_155 ALRVIFPEGFADRIGEAAVNDLADTILRYALMALLIPSVEPLETAD--DI
TH_2255|M.thermoresistible__bu ALRVIFPAGFAERIGEAAVIEFADTILRYAAMALLLPSVQPLDTAD--DI
MMAR_0287|M.marinum_M GIAHTLRRCGADAP-DADLANIADILLRVAVGIIMFPTER-LDTSDDAAV
MUL_4837|M.ulcerans_Agy99 GIAHTLRRCGADAP-DADLANIADILLRVAVGIIMFPTER-LDTSDDAAV
MAV_5227|M.avium_104 GIAHTLRRCGAEQA-EPDLDNIADILLRVALGIIVFPTDR-LDTADPAAV
MAB_3273c|M.abscessus_ATCC_199 VLTLLAMRLMGDGYSEAGARQAAELIMRITGTLLLAPSKILRVETDD-EA
Rv1255c|M.tuberculosis_H37Rv ALAAAFLNSLGPDD-PTTVERRARWVVRMLTSLLMFPGRD--EADERAMI
MLBr_00316|M.leprae_Br4923 DAEDAFLTILSDLLYAAQYAGTARTDVGVREVKSILVGCQAMEAYNS-AL
Mb0710c|M.bovis_AF2122/97 GWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLT
. . : .
Mvan_0855|M.vanbaalenii_PYR-1 RAFARQHFLPSLPAALRTVPA---
Mflv_0059|M.gilvum_PYR-GCK RAFARHHFLPSLPEALRSVPA---
MSMEG_0962|M.smegmatis_MC2_155 RSFATRHFLPSLPVSLRVVPA---
TH_2255|M.thermoresistible__bu RAFATRHFLPSLPAALHTGSA---
MMAR_0287|M.marinum_M REYAARYLIPIITL----------
MUL_4837|M.ulcerans_Agy99 REYAARYLIPIITL----------
MAV_5227|M.avium_104 RDYAARYLVPIIGR----------
MAB_3273c|M.abscessus_ATCC_199 RSFAVTYLVPVLRAARAVTE----
Rv1255c|M.tuberculosis_H37Rv AEFVVPIVTPASAAARKAGHPGPE
MLBr_00316|M.leprae_Br4923 AERVTDVVVDGLRAAR--------
Mb0710c|M.bovis_AF2122/97 EALGAAFDVVGAGLDRLNQ-----