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MRRTRTRNTPTEQESAILKAAAEEVALVGVGRLSMDVVARQAGVSRSTLYRRFPTRDALITELGRQTFDF AMARLQTVAIDSGPQQAAVAAFTEGVRLLTGEPVMRRFLQLDREFTATTEMVEEARLFLVSAATAMAKAL RAAGAGMPDDELLAVAEIHIRLAASLVQVSSDVLDVGDDEAVARYARTYLAPLVH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0969 | - | - | 100% (195) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0855 | - | 5e-08 | 30.96% (197) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0369 | - | 6e-08 | 25.13% (187) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2274c | - | 7e-09 | 25.42% (177) | transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_5272 | - | 3e-92 | 91.24% (194) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv2250c | - | 4e-09 | 26.97% (178) | transcriptional regulator |
| M. leprae Br4923 | MLBr_00064 | - | 5e-06 | 32.89% (76) | putative transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4647 | - | 8e-27 | 39.69% (194) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0287 | - | 5e-26 | 35.14% (185) | transcriptional regulatory protein |
| M. avium 104 | MAV_5227 | - | 8e-22 | 32.97% (185) | TetR-family protein transcriptional regulator, putative |
| M. smegmatis MC2 155 | MSMEG_5340 | - | 1e-08 | 44.78% (67) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_2255 | - | 8e-10 | 30.00% (190) | TetR-family protein transcriptional regulator |
| M. ulcerans Agy99 | MUL_4837 | - | 5e-26 | 35.14% (185) | transcriptional regulatory protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2274c|M.bovis_AF2122/97 --------------MLSMSNDRADTGGRILRAAASCVVDYGVDRVTLAEI
Rv2250c|M.tuberculosis_H37Rv --------------MLSMSNDRADTGGRILRAAASCVVDYGVDRVTLAEI
Mvan_0969|M.vanbaalenii_PYR-1 ------------MRRTRTRNTPTEQESAILKAAAEEVALVGVGRLSMDVV
Mflv_5272|M.gilvum_PYR-GCK ------------MRRARNTDSPTEQESAILKAAAEEVALVGVGRLSMDVV
MMAR_0287|M.marinum_M -----MQSRMGTETSTDGVESITDLDRTILDTARAVFETYGVRRANIEDV
MUL_4837|M.ulcerans_Agy99 ---------MGTETSTDGVESITDLDRTILDTAHAVFETYGVRRANIEDV
MAV_5227|M.avium_104 ---------MQSHRADAAAGERTDLDRLILDTARGVFETYGVRRANIDDV
MAB_4647|M.abscessus_ATCC_1997 ---------MTTLLRVTTSAPPTD---AVLDAARTEFERHGMRRANMDAI
TH_2255|M.thermoresistible__bu -----------------MPERPDPARQAILDAAVVEFEQHGFRKVALEDV
MSMEG_5340|M.smegmatis_MC2_155 -----MAEKSAPRRTSGGPVLLDDVTTAIEKAFFEELAAVGYGRLSVDAV
MLBr_00064|M.leprae_Br4923 MINSTAGQTSQSRSRRSTRPSGDDRELAILATAEQLLEDRPLTEISVDYL
: : . . : :
Mb2274c|M.bovis_AF2122/97 ARRAGVSRPTVYRRWPDTRSIMASMLT---SHIAAVLREVPLDGDDR--E
Rv2250c|M.tuberculosis_H37Rv ARRAGVSRPTVYRRWPDTRSIMASMLT---SHIADVLREVPLDGDDR--E
Mvan_0969|M.vanbaalenii_PYR-1 ARQAGVSRSTLYRRFPTRDALITELGRQTFDFAMARLQTVAIDSGPQ--Q
Mflv_5272|M.gilvum_PYR-GCK ARQAGVSRSTLYRRFPSRDALITELGRQTFEFAMARLQTVAIDDGPQ--Q
MMAR_0287|M.marinum_M ATRAGVSRSTIYRRFPTKDELFERVVRREAELFFAALNQATNGHNPR--E
MUL_4837|M.ulcerans_Agy99 ATRAGVSRSTIYRRFPTKDELFERVVRREAELFFAALNQATNGHNPR--E
MAV_5227|M.avium_104 AARAGVSRSTIYRRFPTKKNLFGQVVRREAELFFSTLDQATAGCDPQ--Q
MAB_4647|M.abscessus_ATCC_1997 ARRAGVSRRTLYRRFPTKEALFEHLIEAESITVFGQLAVAANGQDAP--G
TH_2255|M.thermoresistible__bu ARRAGVSRTTIYRRFTNRDELVAAVVDRENAALFADIAAELKHSGPQG-D
MSMEG_5340|M.smegmatis_MC2_155 ARRAGVGKAAIYRRWRSKQALAADLVAKVAVTAIDVPDTGSLRGDIR--E
MLBr_00064|M.leprae_Br4923 AKSAGISRPTFYFYFASKEAVLLTLLDRVFNKANAALETLIKNRDNKRGN
* **:.: :.* : : : .
Mb2274c|M.bovis_AF2122/97 ALVKQIVAVADRLRGDDLIMSVMHSELARVYITERLGTSQQVLIEGLAAR
Rv2250c|M.tuberculosis_H37Rv ALVKQIVAVADRLRGDDLIMSVMHSELARVYITERLGTSQQVLIEGLAAR
Mvan_0969|M.vanbaalenii_PYR-1 AAVAAFTEGVRLLTGEPVMRRFLQLDREFTATTEMVEEARLFLVSAATAM
Mflv_5272|M.gilvum_PYR-GCK AAVAAFREGVRLLTGEPVMRRFLQLDGEFTATTEMVAEARLFLVSAATAM
MMAR_0287|M.marinum_M AVIEAFTLGVRLIQDSPLYSRIAESEPE--LFGMFSRSHVFPIGQFADGI
MUL_4837|M.ulcerans_Agy99 AVIEAFTLGVRLIRDSPLYSRIAESEPE--LFGMFSRSHVFPIGQFADGI
MAV_5227|M.avium_104 AVIEAFALGVRLVKNSALYSRIAESEPE--LFGLFSRSQVFPIRQFADGI
MAB_4647|M.abscessus_ATCC_1997 AIVECFTLAMRLITESRLAGTIIENEPEL-VIGLNTPSGDKAIVRASALV
TH_2255|M.thermoresistible__bu YYVEAFTLAILKFRRHRVLHRMITDEPGFILHLAQQHWGAAVERMAEALR
MSMEG_5340|M.smegmatis_MC2_155 YLRNGREALTHRLARKIIPDLIAEAVRDPEYGALLTDLIREPRRGRGSHI
MLBr_00064|M.leprae_Br4923 KWRTGINVFFETFGSHKAVTCAGQVTRDNTEVRKLWSTFMQKWISYTAAV
.
Mb2274c|M.bovis_AF2122/97 LTVAQRSGSVRS-GDARRLATMVLLIAQSTIQSA-DIVDSILDSA---AL
Rv2250c|M.tuberculosis_H37Rv LTVAQRSGSVRS-GDARRLATMVLLIAQSTIQSA-DIVDSILDSA---AL
Mvan_0969|M.vanbaalenii_PYR-1 AKALRAAGAGMPDDELLAVAEIHIRLAASLVQVS-SDVLDVGDDE---AV
Mflv_5272|M.gilvum_PYR-GCK AKALRAAGATMPDSELLAVAEVHIRLAASLVQVN-TDVLDVTDDE---AV
MMAR_0287|M.marinum_M AHTLRRCGADAPDADLANIADILLRVAVGIIMFP-TERLDTSDDA---AV
MUL_4837|M.ulcerans_Agy99 AHTLRRCGADAPDADLANIADILLRVAVGIIMFP-TERLDTSDDA---AV
MAV_5227|M.avium_104 AHTLRRCGAEQAEPDLDNIADILLRVALGIIVFP-TDRLDTADPA---AV
MAB_4647|M.abscessus_ATCC_1997 ASSLRHSGATMPDDAVLAVSEILVRLVGSLLTNR-AGVLDITDTA---AV
TH_2255|M.thermoresistible__bu VIFPAGFAERIGEAAVIEFADTILRYAAMALLLPSVQPLDTADDIRAFAT
MSMEG_5340|M.smegmatis_MC2_155 FERAIERGEIAPDADID----VALDVLAGALYWRQSILQTTADDD---YL
MLBr_00064|M.leprae_Br4923 IDAERKRGVAPDTLPATELATALNLMNERALFASFTAEQPHVPESR--VL
. :
Mb2274c|M.bovis_AF2122/97 ATELTHALNGYLC---
Rv2250c|M.tuberculosis_H37Rv ATELTHALNGYLC---
Mvan_0969|M.vanbaalenii_PYR-1 ARYARTYLAPLVH---
Mflv_5272|M.gilvum_PYR-GCK ARYARTYLAPLVR---
MMAR_0287|M.marinum_M REYAARYLIPIITL--
MUL_4837|M.ulcerans_Agy99 REYAARYLIPIITL--
MAV_5227|M.avium_104 RDYAARYLVPIIGR--
MAB_4647|M.abscessus_ATCC_1997 RHYAQTYLARLVW---
TH_2255|M.thermoresistible__bu RHFLPSLPAALHTGSA
MSMEG_5340|M.smegmatis_MC2_155 DRLTEVVLMAVGMGK-
MLBr_00064|M.leprae_Br4923 DTLVHIWVSSIYNEIR