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DLGLVWSQLSSGQSALGDEDEERERLLDAARVEFVAHGFRRAAVADIAKRANVSRQTLNRRCGDKDDMVS AVVGREVLQFFVTLAPLLDPKDNVEDQVVELFVTGMRECRVNPVVAALKEYETESMSVGLFATEHGNYQA VLTLLAMRLMGDGYSEAGARQAAELIMRITGTLLLAPSKILRVETDDEARSFAVTYLVPVLRAARAVTE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3273c | - | - | 100% (210) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2152 | - | 7e-49 | 48.06% (206) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1024 | - | 1e-16 | 30.05% (193) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0237 | - | 8e-08 | 29.00% (200) | TetR/ACRR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0059 | - | 8e-17 | 34.38% (192) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0232 | - | 9e-08 | 29.00% (200) | TetR/ACRR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02568 | - | 2e-05 | 26.12% (134) | putative TetR-family transcriptional regulator |
| M. marinum M | MMAR_0287 | - | 3e-18 | 30.56% (180) | transcriptional regulatory protein |
| M. avium 104 | MAV_5227 | - | 4e-15 | 30.43% (207) | TetR-family protein transcriptional regulator, putative |
| M. smegmatis MC2 155 | MSMEG_0962 | - | 6e-19 | 33.33% (189) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_2255 | - | 5e-19 | 33.16% (190) | TetR-family protein transcriptional regulator |
| M. ulcerans Agy99 | MUL_4837 | - | 2e-18 | 30.56% (180) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_0855 | - | 2e-19 | 35.98% (189) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0237|M.bovis_AF2122/97 ----------MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIAR
Rv0232|M.tuberculosis_H37Rv ----------MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIAR
Mflv_0059|M.gilvum_PYR-GCK ---------------MS-GPDPASEQILDAAVVEFERHGFRRVALEDVAR
Mvan_0855|M.vanbaalenii_PYR-1 ---------------MR-GTD-ATEHILDAAVVEFERHGFRRVALDDVAR
MSMEG_0962|M.smegmatis_MC2_155 ---------------MP-GPDAASRAILDAALVEFERYGFRRVALDDVAR
TH_2255|M.thermoresistible__bu ---------------MPERPDPARQAILDAAVVEFEQHGFRKVALEDVAR
MMAR_0287|M.marinum_M ---MQSRMGTETSTDGVESITDLDRTILDTARAVFETYGVRRANIEDVAT
MUL_4837|M.ulcerans_Agy99 -------MGTETSTDGVESITDLDRTILDTAHAVFETYGVRRANIEDVAT
MAV_5227|M.avium_104 -------MQSHRADAAAGERTDLDRLILDTARGVFETYGVRRANIDDVAA
MAB_3273c|M.abscessus_ATCC_199 MDLGLVWSQLSSGQSALGDEDEERERLLDAARVEFVAHGFRRAAVADIAK
MLBr_02568|M.leprae_Br4923 ----------MAGGAKRIPRAVREQQMLDAAVQMFSVNGYHKTSMDAIAA
::::* * * : : :*
Mb0237|M.bovis_AF2122/97 RAGVAKGSLFQYFADKRDLYAFIADIASQRVRSYMEDLIRELDPNRPFFE
Rv0232|M.tuberculosis_H37Rv RAGVAKGSLFQYFADKRDLYAFIADIASQRVRSYMEDLIRELDPNRPFFE
Mflv_0059|M.gilvum_PYR-GCK RAGVSRTTIYRRFANKD---QLVGAVIERENVALFSDIATELKQAGPQSN
Mvan_0855|M.vanbaalenii_PYR-1 RAGVSRTTIYRRFANKD---ELVGAVIERENIQLFADIAAELKTAGPQSN
MSMEG_0962|M.smegmatis_MC2_155 RAGVSRTTIYRRFANRD---DLVGAVIERENVSLFADIAAELKDAKPQSN
TH_2255|M.thermoresistible__bu RAGVSRTTIYRRFTNRD---ELVAAVVDRENAALFADIAAELKHSGPQGD
MMAR_0287|M.marinum_M RAGVSRSTIYRRFPTKD---ELFERVVRREAELFFAALNQATNGHNPR-E
MUL_4837|M.ulcerans_Agy99 RAGVSRSTIYRRFPTKD---ELFERVVRREAELFFAALNQATNGHNPR-E
MAV_5227|M.avium_104 RAGVSRSTIYRRFPTKK---NLFGQVVRREAELFFSTLDQATAGCDPQ-Q
MAB_3273c|M.abscessus_ATCC_199 RANVSRQTLNRRCGDKD---DMVSAVVGREVLQFFVTLAPLLDPKDNVED
MLBr_02568|M.leprae_Br4923 EAQISKPMLYLYYGSKE---DLFGACLNREMSRFIAMVRADIDFTQSPKD
.* ::: : : :. :. : : :
Mb0237|M.bovis_AF2122/97 FLTDLLDGWVAYFAEHPRERALHAAATLEVDTDARISVRSVLHRHYLDVL
Rv0232|M.tuberculosis_H37Rv FLTDLLDGWVAYFAEHPRERALHAAATLEVDTDARISVRSVLHRHYLDVL
Mflv_0059|M.gilvum_PYR-GCK YYVEAFTLSILKFRGHRVLHRMITEEPGLVLELASLYY-RAAIERMAEAL
Mvan_0855|M.vanbaalenii_PYR-1 YYVEAFTLSILKFRRHRVLHQMIIDEPGLVLELAGRYH-RAAIDRMAAAL
MSMEG_0962|M.smegmatis_MC2_155 IYVEAFTLSILRFRRHRVLNQMMKDEPALVLELAHRHY-GAAIERMAAAL
TH_2255|M.thermoresistible__bu YYVEAFTLAILKFRRHRVLHRMITDEPGFILHLAQQHW-GAAVERMAEAL
MMAR_0287|M.marinum_M AVIEAFTLGVRLIQDSPLYSRIAESEP-ELFGMFSRSH-VFPIGQFADGI
MUL_4837|M.ulcerans_Agy99 AVIEAFTLGVRLIRDSPLYSRIAESEP-ELFGMFSRSH-VFPIGQFADGI
MAV_5227|M.avium_104 AVIEAFALGVRLVKNSALYSRIAESEP-ELFGLFSRSQ-VFPIRQFADGI
MAB_3273c|M.abscessus_ATCC_199 QVVELFVTGMRECRVNPVVAALKEYET---ESMSVGLF-ATEHGNYQAVL
MLBr_02568|M.leprae_Br4923 LLRNTIVSFLRYIDANRASWIVMYIQAMSLPAFAQTVR--EARDQITELV
: : : : . . :
Mb0237|M.bovis_AF2122/97 RPLVRDAHARGDLRADSDTGALMSLLLLIFPHLALAPYMRGLDPILGLDE
Rv0232|M.tuberculosis_H37Rv RPLVRDAHARGDLRADSDTGALMSLLLLIFPHLALAPYMRGLDPILGLDE
Mflv_0059|M.gilvum_PYR-GCK RVIFPPGFA--ERIGADAVDELADTILRYATMVLLLPSAQPLETAD----
Mvan_0855|M.vanbaalenii_PYR-1 RVIFPPGFA--ERIGPAAVDELADCILRYAAMVLLLPSAQPLETAD----
MSMEG_0962|M.smegmatis_MC2_155 RVIFPEGFA--DRIGEAAVNDLADTILRYALMALLIPSVEPLETAD----
TH_2255|M.thermoresistible__bu RVIFPAGFA--ERIGEAAVIEFADTILRYAAMALLLPSVQPLDTAD----
MMAR_0287|M.marinum_M AHTLRRCGA--DAP-DADLANIADILLRVAVGIIMFPTER-LDTSDDA--
MUL_4837|M.ulcerans_Agy99 AHTLRRCGA--DAP-DADLANIADILLRVAVGIIMFPTER-LDTSDDA--
MAV_5227|M.avium_104 AHTLRRCGA--EQA-EPDLDNIADILLRVALGIIVFPTDR-LDTADPA--
MAB_3273c|M.abscessus_ATCC_199 TLLAMRLMG--DGYSEAGARQAAELIMRITGTLLLAPSKILRVETDD---
MLBr_02568|M.leprae_Br4923 AGLMRVGTR--SSRPDHEYEIMAGALVGAGEAMATRLTTGDIAVDEAA--
. ::
Mb0237|M.bovis_AF2122/97 PTPEQPALAVRRLVAVLAAAFDAQHPATNSAQTRSEEIT
Rv0232|M.tuberculosis_H37Rv PTPEQPALAVRRLVAVLAAAFDAQHPATNSAQTRSEEIT
Mflv_0059|M.gilvum_PYR-GCK ---DIRAFARHHFLPSLPEALRSVPA-------------
Mvan_0855|M.vanbaalenii_PYR-1 ---DVRAFARQHFLPSLPAALRTVPA-------------
MSMEG_0962|M.smegmatis_MC2_155 ---DIRSFATRHFLPSLPVSLRVVPA-------------
TH_2255|M.thermoresistible__bu ---DIRAFATRHFLPSLPAALHTGSA-------------
MMAR_0287|M.marinum_M ---AVREYAARYLIPIITL--------------------
MUL_4837|M.ulcerans_Agy99 ---AVREYAARYLIPIITL--------------------
MAV_5227|M.avium_104 ---AVRDYAARYLVPIIGR--------------------
MAB_3273c|M.abscessus_ATCC_199 ---EARSFAVTYLVPVLRAARAVTE--------------
MLBr_02568|M.leprae_Br4923 ---ELMINLFWHGLKGAPADRDFGPSIVAG---------
: