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QSRMGTETSTDGVESITDLDRTILDTARAVFETYGVRRANIEDVATRAGVSRSTIYRRFPTKDELFERVV RREAELFFAALNQATNGHNPREAVIEAFTLGVRLIQDSPLYSRIAESEPELFGMFSRSHVFPIGQFADGI AHTLRRCGADAPDADLANIADILLRVAVGIIMFPTERLDTSDDAAVREYAARYLIPIITL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0287 | - | - | 100% (201) | transcriptional regulatory protein |
| M. marinum M | MMAR_4185 | - | 3e-10 | 28.33% (180) | transcriptional regulatory protein |
| M. marinum M | MMAR_3161 | - | 6e-09 | 25.27% (182) | transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3198c | - | 2e-07 | 27.53% (178) | TetR/ACRR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_5272 | - | 2e-26 | 34.57% (188) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1255c | - | 2e-09 | 27.78% (180) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_00815 | - | 5e-07 | 32.50% (80) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4647 | - | 2e-32 | 42.37% (177) | TetR family transcriptional regulator |
| M. avium 104 | MAV_5227 | - | 8e-79 | 79.67% (182) | TetR-family protein transcriptional regulator, putative |
| M. smegmatis MC2 155 | MSMEG_0962 | - | 3e-21 | 34.38% (192) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_2255 | - | 9e-20 | 33.85% (192) | TetR-family protein transcriptional regulator |
| M. ulcerans Agy99 | MUL_4837 | - | 1e-107 | 98.98% (197) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_0969 | - | 5e-26 | 35.14% (185) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0287|M.marinum_M --------------------MQSRMGTETSTDGVESITDLDRTILDTARA
MUL_4837|M.ulcerans_Agy99 ------------------------MGTETSTDGVESITDLDRTILDTAHA
MAV_5227|M.avium_104 ------------------------MQSHRADAAAGERTDLDRLILDTARG
MAB_4647|M.abscessus_ATCC_1997 ------------------------MTTLLRVTTSAPPTD---AVLDAART
Mflv_5272|M.gilvum_PYR-GCK ---------------------------MRRARNTDSPTEQESAILKAAAE
Mvan_0969|M.vanbaalenii_PYR-1 ---------------------------MRRTRTRNTPTEQESAILKAAAE
MSMEG_0962|M.smegmatis_MC2_155 --------------------------------MP-GPDAASRAILDAALV
TH_2255|M.thermoresistible__bu --------------------------------MPERPDPARQAILDAAVV
Rv1255c|M.tuberculosis_H37Rv -------------------------MAGTDWLSARRTELAADRILDAAER
Mb3198c|M.bovis_AF2122/97 ----------------------MPPVTRTTEPPRRGGRGARQRILKAAAE
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
:* .*
MMAR_0287|M.marinum_M VFETYGVRRANIEDVATRAGVSRSTIYRRFPTKDELFERVVRREAELFFA
MUL_4837|M.ulcerans_Agy99 VFETYGVRRANIEDVATRAGVSRSTIYRRFPTKDELFERVVRREAELFFA
MAV_5227|M.avium_104 VFETYGVRRANIDDVAARAGVSRSTIYRRFPTKKNLFGQVVRREAELFFS
MAB_4647|M.abscessus_ATCC_1997 EFERHGMRRANMDAIARRAGVSRRTLYRRFPTKEALFEHLIEAESITVFG
Mflv_5272|M.gilvum_PYR-GCK EVALVGVGRLSMDVVARQAGVSRSTLYRRFPSRDALITELGRQTFEFAMA
Mvan_0969|M.vanbaalenii_PYR-1 EVALVGVGRLSMDVVARQAGVSRSTLYRRFPTRDALITELGRQTFDFAMA
MSMEG_0962|M.smegmatis_MC2_155 EFERYGFRRVALDDVARRAGVSRTTIYRRFANRDDLVGAVIERENVSLFA
TH_2255|M.thermoresistible__bu EFEQHGFRKVALEDVARRAGVSRTTIYRRFTNRDELVAAVVDRENAALFA
Rv1255c|M.tuberculosis_H37Rv LFTQRDPASIGMNEIAKAAGCSRATLYRYFDSREALRTAYVHRETRRLGR
Mb3198c|M.bovis_AF2122/97 LFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYLRGLRQAAGE
MLBr_00815|M.leprae_Br4923 VFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLVS
. . :: :* *. *: .:*: * .: *
MMAR_0287|M.marinum_M ALNQATNGHNPR-EAVIEAFTLGVR---LIQDSPLYSRIAESEPE--LFG
MUL_4837|M.ulcerans_Agy99 ALNQATNGHNPR-EAVIEAFTLGVR---LIRDSPLYSRIAESEPE--LFG
MAV_5227|M.avium_104 TLDQATAGCDPQ-QAVIEAFALGVR---LVKNSALYSRIAESEPE--LFG
MAB_4647|M.abscessus_ATCC_1997 QLAVAANGQDAP-GAIVECFTLAMR---LITESRLAGTIIENEPEL-VIG
Mflv_5272|M.gilvum_PYR-GCK RLQTVAIDDGPQ-QAAVAAFREGVR---LLTGEPVMRRFLQLDGEFTATT
Mvan_0969|M.vanbaalenii_PYR-1 RLQTVAIDSGPQ-QAAVAAFTEGVR---LLTGEPVMRRFLQLDREFTATT
MSMEG_0962|M.smegmatis_MC2_155 DIAAELKDAKPQSNIYVEAFTLSIL---RFRRHRVLNQMMKDEPALVLEL
TH_2255|M.thermoresistible__bu DIAAELKHSGPQGDYYVEAFTLAIL---KFRRHRVLHRMITDEPGFILHL
Rv1255c|M.tuberculosis_H37Rv EIMVKIADVVEPAERLLVSITTTLR---MVRDNPALAAWFTTTRP-----
Mb3198c|M.bovis_AF2122/97 ADKMPKASNATPRERLLALFDRPNRGDGRMRGCPFHNAAVEAAGEMPGVE
MLBr_00815|M.leprae_Br4923 SVQQALRTTTNNRQRLHAAVQAFFD---FIEHDGQGYRLIFENDNITEPR
. .
MMAR_0287|M.marinum_M MFSRSHVFPIGQFADGIAHTLRRCGADAPDADLANIADILLRVAVGIIMF
MUL_4837|M.ulcerans_Agy99 MFSRSHVFPIGQFADGIAHTLRRCGADAPDADLANIADILLRVAVGIIMF
MAV_5227|M.avium_104 LFSRSQVFPIRQFADGIAHTLRRCGAEQAEPDLDNIADILLRVALGIIVF
MAB_4647|M.abscessus_ATCC_1997 LNTPSGDKAIVRASALVASSLRHSGATMPDDAVLAVSEILVRLVGSLLTN
Mflv_5272|M.gilvum_PYR-GCK EMVAEARLFLVSAATAMAKALRAAGATMPDSELLAVAEVHIRLAASLVQV
Mvan_0969|M.vanbaalenii_PYR-1 EMVEEARLFLVSAATAMAKALRAAGAGMPDDELLAVAEIHIRLAASLVQV
MSMEG_0962|M.smegmatis_MC2_155 AHRHYGAAIERMAAALRVIFPEGFADRIGEAAVNDLADTILRYALMALLI
TH_2255|M.thermoresistible__bu AQQHWGAAVERMAEALRVIFPAGFAERIGEAAVIEFADTILRYAAMALLL
Rv1255c|M.tuberculosis_H37Rv PIGGEMAGRSEVIAALAAAFLNSLGPDDP-TTVERRARWVVRMLTSLLMF
Mb3198c|M.bovis_AF2122/97 RIVHS---HKRDYIKGLARLAREAGAAHPRSLGNQLAVLFEGAAALSTSL
MLBr_00815|M.leprae_Br4923 VAAQVRVATESCIDAVFALISADSRLDPHRARMVAVGLVGISVDCARYWL
. .
MMAR_0287|M.marinum_M P-TERLDTSDDA---AVREYAARYLIPIITL-----
MUL_4837|M.ulcerans_Agy99 P-TERLDTSDDA---AVREYAARYLIPIITL-----
MAV_5227|M.avium_104 P-TDRLDTADPA---AVRDYAARYLVPIIGR-----
MAB_4647|M.abscessus_ATCC_1997 R-AGVLDITDTA---AVRHYAQTYLARLVW------
Mflv_5272|M.gilvum_PYR-GCK N-TDVLDVTDDE---AVARYARTYLAPLVR------
Mvan_0969|M.vanbaalenii_PYR-1 S-SDVLDVGDDE---AVARYARTYLAPLVH------
MSMEG_0962|M.smegmatis_MC2_155 PSVEPLETADDIRSFATRHFLPSLPVSLRVVPA---
TH_2255|M.thermoresistible__bu PSVQPLDTADDIRAFATRHFLPSLPAALHTGSA---
Rv1255c|M.tuberculosis_H37Rv PGRDEADERAMIAEFVVPIVTPASAAARKAGHPGPE
Mb3198c|M.bovis_AF2122/97 DDAGPWAHARAA---AEVLIDQATARPV--------
MLBr_00815|M.leprae_Br4923 DTNRPISKSDAVEGTVQFAWGGLSHVPLTRL-----
.