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MQSHRADAAAGERTDLDRLILDTARGVFETYGVRRANIDDVAARAGVSRSTIYRRFPTKKNLFGQVVRRE AELFFSTLDQATAGCDPQQAVIEAFALGVRLVKNSALYSRIAESEPELFGLFSRSQVFPIRQFADGIAHT LRRCGAEQAEPDLDNIADILLRVALGIIVFPTDRLDTADPAAVRDYAARYLVPIIGR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_5227 | - | - | 100% (197) | TetR-family protein transcriptional regulator, putative |
| M. avium 104 | MAV_2157 | - | 2e-14 | 31.03% (174) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_2883 | - | 1e-11 | 29.03% (186) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3323 | - | 3e-07 | 28.10% (153) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_5272 | - | 9e-22 | 32.97% (185) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3295 | - | 3e-07 | 28.10% (153) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00717 | - | 8e-07 | 25.44% (169) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4647 | - | 5e-29 | 40.68% (177) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0287 | - | 1e-78 | 79.67% (182) | transcriptional regulatory protein |
| M. smegmatis MC2 155 | MSMEG_0962 | - | 4e-20 | 35.00% (180) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_2255 | - | 1e-15 | 33.16% (187) | TetR-family protein transcriptional regulator |
| M. ulcerans Agy99 | MUL_4837 | - | 2e-78 | 79.12% (182) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_0969 | - | 1e-21 | 32.97% (185) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0287|M.marinum_M MQSRMGTETSTDGVESITDLDRTILDTARAVFETYGVRRANIEDVATRAG
MUL_4837|M.ulcerans_Agy99 ----MGTETSTDGVESITDLDRTILDTAHAVFETYGVRRANIEDVATRAG
MAV_5227|M.avium_104 ----MQSHRADAAAGERTDLDRLILDTARGVFETYGVRRANIDDVAARAG
Mflv_5272|M.gilvum_PYR-GCK -------MRRARNTDSPTEQESAILKAAAEEVALVGVGRLSMDVVARQAG
Mvan_0969|M.vanbaalenii_PYR-1 -------MRRTRTRNTPTEQESAILKAAAEEVALVGVGRLSMDVVARQAG
MAB_4647|M.abscessus_ATCC_1997 -------MTTLLRVTTSAPPTDAVLDAARTEFERHGMRRANMDAIARRAG
MSMEG_0962|M.smegmatis_MC2_155 ------------MP-GPDAASRAILDAALVEFERYGFRRVALDDVARRAG
TH_2255|M.thermoresistible__bu ------------MPERPDPARQAILDAAVVEFEQHGFRKVALEDVARRAG
Mb3323|M.bovis_AF2122/97 -------MATARRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAG
Rv3295|M.tuberculosis_H37Rv -------MATARRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAG
MLBr_00717|M.leprae_Br4923 -------MTTARRRLSPEDRRAELLALGAEVFGKRPYDEVRIDEIAERAG
:* . . . :: :* :**
MMAR_0287|M.marinum_M VSRSTIYRRFPTKDELFERVVRREAELFFAALNQATNGHNPR-EAVIEAF
MUL_4837|M.ulcerans_Agy99 VSRSTIYRRFPTKDELFERVVRREAELFFAALNQATNGHNPR-EAVIEAF
MAV_5227|M.avium_104 VSRSTIYRRFPTKKNLFGQVVRREAELFFSTLDQATAGCDPQ-QAVIEAF
Mflv_5272|M.gilvum_PYR-GCK VSRSTLYRRFPSRDALITELGRQTFEFAMARLQTVAIDDGPQ-QAAVAAF
Mvan_0969|M.vanbaalenii_PYR-1 VSRSTLYRRFPTRDALITELGRQTFDFAMARLQTVAIDSGPQ-QAAVAAF
MAB_4647|M.abscessus_ATCC_1997 VSRRTLYRRFPTKEALFEHLIEAESITVFGQLAVAANGQDAP-GAIVECF
MSMEG_0962|M.smegmatis_MC2_155 VSRTTIYRRFANRDDLVGAVIERENVSLFADIAAELKDAKPQSNIYVEAF
TH_2255|M.thermoresistible__bu VSRTTIYRRFTNRDELVAAVVDRENAALFADIAAELKHSGPQGDYYVEAF
Mb3323|M.bovis_AF2122/97 VSRALMYHYFPDKRAFFAAVVKDEADRLYAATNKAPAPGMTMFEEIRTGV
Rv3295|M.tuberculosis_H37Rv VSRALMYHYFPDKRAFFAAVVKDEADRLYAATNKAPAPGMTMFEEIRTGV
MLBr_00717|M.leprae_Br4923 VSRALMYHYFPDKRAFFAAVVKDEADRLYAATNIPPPAGLTMFEEVRVGV
*** :*: *. : :. : . . .
MMAR_0287|M.marinum_M TLGVRLIQDSP-----LYSRIAESEPELFGMFSR--SHVFPIGQFADGIA
MUL_4837|M.ulcerans_Agy99 TLGVRLIRDSP-----LYSRIAESEPELFGMFSR--SHVFPIGQFADGIA
MAV_5227|M.avium_104 ALGVRLVKNSA-----LYSRIAESEPELFGLFSR--SQVFPIRQFADGIA
Mflv_5272|M.gilvum_PYR-GCK REGVRLLTGEP-----VMRRFLQLDGEFTATTEMVAEARLFLVSAATAMA
Mvan_0969|M.vanbaalenii_PYR-1 TEGVRLLTGEP-----VMRRFLQLDREFTATTEMVEEARLFLVSAATAMA
MAB_4647|M.abscessus_ATCC_1997 TLAMRLITESR-----LAGTIIENEPELVIGLNTPSGDK-AIVRASALVA
MSMEG_0962|M.smegmatis_MC2_155 TLSILRFRRHR-----VLNQMMKDEPALVLELAHRHYGAAIERMAAALRV
TH_2255|M.thermoresistible__bu TLAILKFRRHR-----VLHRMITDEPGFILHLAQQHWGAAVERMAEALRV
Mb3323|M.bovis_AF2122/97 LAYMAYHQQNPEAAWAAYVGLGRSDPVLLGIDDEAKNRQMEHIMSRIAEV
Rv3295|M.tuberculosis_H37Rv LAYMAYHQQNPEAAWAAYVGLGRSDPVLLGIDDEAKNRQMEHIMSRIAEV
MLBr_00717|M.leprae_Br4923 LAYMAYHKQNPEAAWAAYVGLGRSDPVLLGIDDEAKNRQMEHIMSRIGDV
: : : : .
MMAR_0287|M.marinum_M HTLRRCGADAPDADLANIADILLRVAVGIIMFP-TERLDTSDDA---AVR
MUL_4837|M.ulcerans_Agy99 HTLRRCGADAPDADLANIADILLRVAVGIIMFP-TERLDTSDDA---AVR
MAV_5227|M.avium_104 HTLRRCGAEQAEPDLDNIADILLRVALGIIVFP-TDRLDTADPA---AVR
Mflv_5272|M.gilvum_PYR-GCK KALRAAGATMPDSELLAVAEVHIRLAASLVQVN-TDVLDVTDDE---AVA
Mvan_0969|M.vanbaalenii_PYR-1 KALRAAGAGMPDDELLAVAEIHIRLAASLVQVS-SDVLDVGDDE---AVA
MAB_4647|M.abscessus_ATCC_1997 SSLRHSGATMPDDAVLAVSEILVRLVGSLLTNR-AGVLDITDTA---AVR
MSMEG_0962|M.smegmatis_MC2_155 IFPEGFADRIGEAAVNDLADTILRYALMALLIPSVEPLETADDIRSFATR
TH_2255|M.thermoresistible__bu IFPAGFAERIGEAAVIEFADTILRYAAMALLLPSVQPLDTADDIRAFATR
Mb3323|M.bovis_AF2122/97 VSGIDRDNTLDPEVERDLRVIIHGWLAFTFELCRQRIMDPSTDAER-LAD
Rv3295|M.tuberculosis_H37Rv VSGIDRDNTLDPEVERDLRVIIHGWLAFTFELCRQRIMDPSTDAER-LAD
MLBr_00717|M.leprae_Br4923 VSVVP-ESKLHPDIERDLRVIVHGWLAFTFEVCRQRIMDPSTDADR-LAD
. . :: .
MMAR_0287|M.marinum_M EYAARYLIPIITL-------------------
MUL_4837|M.ulcerans_Agy99 EYAARYLIPIITL-------------------
MAV_5227|M.avium_104 DYAARYLVPIIGR-------------------
Mflv_5272|M.gilvum_PYR-GCK RYARTYLAPLVR--------------------
Mvan_0969|M.vanbaalenii_PYR-1 RYARTYLAPLVH--------------------
MAB_4647|M.abscessus_ATCC_1997 HYAQTYLARLVW--------------------
MSMEG_0962|M.smegmatis_MC2_155 HFLPSLPVSLRVVPA-----------------
TH_2255|M.thermoresistible__bu HFLPSLPAALHTGSA-----------------
Mb3323|M.bovis_AF2122/97 ACAHALLDAISRLPQIPAELADAMATARM---
Rv3295|M.tuberculosis_H37Rv ACAHALLDAISRLPQIPAELADAMATARM---
MLBr_00717|M.leprae_Br4923 SCAHALLDAIARVPEISKELADAMAIARQPPQ
: