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AGTDWLSARRTELAADRILDAAERLFTQRDPASIGMNEIAKAAGCSRATLYRYFDSREALRTAYVHRETR RLGREIMVKIADVVEPAERLLVSITTTLRMVRDNPALAAWFTTTRPPIGGEMAGRSEVIAALAAAFLNSL GPDDPTTVERRARWVVRMLTSLLMFPGRDEADERAMIAEFVVPIVTPASAAARKAGHPGPE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1255c | - | - | 100% (202) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. tuberculosis H37Rv | Rv1776c | - | 2e-15 | 27.72% (184) | transcriptional regulatory protein |
| M. tuberculosis H37Rv | Rv3249c | - | 3e-09 | 26.60% (188) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1287c | - | 9e-25 | 100.00% (52) | hypothetical protein Mb1287c |
| M. gilvum PYR-GCK | Mflv_2228 | - | 1e-61 | 59.90% (202) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_01070 | - | 2e-05 | 41.07% (56) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1938c | - | 6e-20 | 30.69% (189) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4185 | - | 4e-81 | 76.06% (188) | transcriptional regulatory protein |
| M. avium 104 | MAV_1403 | - | 7e-78 | 75.00% (188) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5040 | - | 3e-60 | 58.85% (192) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2228 | - | 4e-59 | 59.68% (186) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. ulcerans Agy99 | MUL_4487 | - | 3e-81 | 76.06% (188) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_4466 | - | 4e-64 | 62.89% (194) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1255c|M.tuberculosis_H37Rv --MAG----TDWLSAR--------RTELAADRILDAAERLFTQRDPASIG
Mb1287c|M.bovis_AF2122/97 --MN-----TDVLAGL--------MAELPEG-------------------
Mflv_2228|M.gilvum_PYR-GCK --MAG-----DWLAAR--------RTEVAADRILDAAGELFAAQSAATVG
Mvan_4466|M.vanbaalenii_PYR-1 --MAG-----DWLAAR--------RTEVAADRILDAAGELFAAQPAATVG
MSMEG_5040|M.smegmatis_MC2_155 --MA------DWLAGR--------RGEVAADLILDAADALFARKDAATVG
TH_2228|M.thermoresistible__bu --MTG-----NWLADR--------RTEVAAERILDAAHELFTRHDAATVG
MMAR_4185|M.marinum_M --MG----RTDWLAAH--------RSEVAADRILDAAERLYTEHDPASIG
MUL_4487|M.ulcerans_Agy99 --MG----RTDWLAAH--------RSEVAADRILDAAERLYTEHDPASIG
MAV_1403|M.avium_104 --MPGARRSTDWLSGH--------RNEAAVDRILDAAQELYTQRDSESIG
MAB_1938c|M.abscessus_ATCC_199 --MSP---YADWLHGSD-------RHTIAADRIVSVAAKQIARHGLDRLN
MLBr_01070|M.leprae_Br4923 MIVVGNFTQSNYVPASRGRRSSQLSGDDREQAILAVAERLLAERPLGDFS
: : :
Rv1255c|M.tuberculosis_H37Rv MNEIAKAAGCSRATLYRYFDSREALRTAYVHRETRRLGREIMVKIADV-V
Mb1287c|M.bovis_AF2122/97 --------------------------------------------------
Mflv_2228|M.gilvum_PYR-GCK MHEIAAAAGCSRATLYRYFENREALYTAYVHRESYRLYREMTEQIMSF-D
Mvan_4466|M.vanbaalenii_PYR-1 MHEIASAAGCSRATLYRYFENREALYTAYVHREAYRLYVEMTDQITSI-A
MSMEG_5040|M.smegmatis_MC2_155 MHEIAAAAGCSRATLYRYFENRDALYTAYVHREARRVYQEVSDQVVGI-G
TH_2228|M.thermoresistible__bu MRDIARAAGCSRATLYRYFDSREALHTAYVHREARRLYRELGPRLAAI-G
MMAR_4185|M.marinum_M MNEIARAAGCSRATLYRYFESREALRTAYVHRETLRLGREIMQQIGDI-D
MUL_4487|M.ulcerans_Agy99 MNEIARAAGCSRATLYRYFESREALRTAYVHRETLRLGREIMQQIGDI-D
MAV_1403|M.avium_104 MNEIARAAGCSRATLYRYFENREALRTAYVHREANRLGRAIMEQIDGI-D
MAB_1938c|M.abscessus_ATCC_199 LDAVAREAGCSRATVYRHVGGKTAIVDAVLARNIAKVTADIQRAVQS--A
MLBr_01070|M.leprae_Br4923 VDELAKGAGISRPTFYFYFPSKNAVLLSLLDDLNMKSRSAVEALAEQLPA
Rv1255c|M.tuberculosis_H37Rv EPAERLLVSITTTLRMVRDNPALAAWFTTTRPPIGGEMAGRSEVIAALAA
Mb1287c|M.bovis_AF2122/97 ---------------MVVTDPAVTDGYRQDR-------------------
Mflv_2228|M.gilvum_PYR-GCK DPRERLIEGMLSSLRNVRESPALSSWFATTQRPIGAEMAEQSEVIKALTE
Mvan_4466|M.vanbaalenii_PYR-1 DPRERLIEGMLASLRNVRESPALASWFATTQRPIGAEMAEESEVIKALTE
MSMEG_5040|M.smegmatis_MC2_155 DPAERLMEGVITALRAVRCSPALSSWFAATQRPIGGEMAEHSEVIRALVE
TH_2228|M.thermoresistible__bu DPQNRLIEGILAALDAVRENPALSSWFAAGHRPVGAELADRSEVIHGLVA
MMAR_4185|M.marinum_M DPRDQLITSITATLRMVRQRPALAAWFASTRPPIGGELAGQSEVIAGLAA
MUL_4487|M.ulcerans_Agy99 DPRDQLITSITATLRMVRQRPALAAWFASTRPPIGGELAGQSEVIAGLAA
MAV_1403|M.avium_104 EPRQRLTASITTTLRMVRGNPALASWFAVTRPPIAGELAEHSEVITALAA
MAB_1938c|M.abscessus_ATCC_199 DARRRAVVAITASLTAIRHDPVISTMIATMSPTSLGSYLNASSEIPRSAS
MLBr_01070|M.leprae_Br4923 DPAAVWRSAITAFFEVCGTHRAVAVAGAAAKATSPEVRRLWSTVMQQWID
.::
Rv1255c|M.tuberculosis_H37Rv AFLNSLGPDDPTTV-----------ERRARWVVRMLTSLLMFPGRDEADE
Mb1287c|M.bovis_AF2122/97 AFDPSAGKPLAIIR-----------PRRARWVVRMLTSLLMFPGRDEADE
Mflv_2228|M.gilvum_PYR-GCK AFVISLG-PDDADARASGATGEGSVAHRSRWLVRVMTSLMLFPGHDEADE
Mvan_4466|M.vanbaalenii_PYR-1 AFVISLG-PDDAEL----------VAHRARWLVRVMTSLMLFPGHDETDE
MSMEG_5040|M.smegmatis_MC2_155 GFVRSLGSPTDADD-------DAAVGRRARWLVRVMVSLLVFPGVDEADE
TH_2228|M.thermoresistible__bu GFLRSQGFDDDG--------------RRARWLVRVIVSLLLFPGRDEAEE
MMAR_4185|M.marinum_M AFLQSLGPEAPAA-----------VERRARWTVRVIVSLLMFPGQDEADE
MUL_4487|M.ulcerans_Agy99 AFLQSLGPEAPAA-----------VERRARWTVRVIVSLLMFPGQDEADE
MAV_1403|M.avium_104 AFVGSLGPEEPAV-----------VERRARWVVRVITSLLLFPGHDEADE
MAB_1938c|M.abscessus_ATCC_199 AFTGLAD------------------ETAAQWISRVVMALLFWPTSDPAQE
MLBr_01070|M.leprae_Br4923 YNTAAIQAERKCGVAP------DTIPAEDLAVALQLMTERVMAATFSDEK
: : . . ::
Rv1255c|M.tuberculosis_H37Rv RAMIAEFVVPIVTPASAAARKAGHPGPE------------------
Mb1287c|M.bovis_AF2122/97 RAMIAEFVVPIVTPASAAARKAGHPGPE------------------
Mflv_2228|M.gilvum_PYR-GCK RAMLEEFVVPIVLPRRQADQATQ-----------------------
Mvan_4466|M.vanbaalenii_PYR-1 RAMLEEFVVPTVLPSRHAAR--------------------------
MSMEG_5040|M.smegmatis_MC2_155 RTMLADFVAPLVVG-AQAAQ--------------------------
TH_2228|M.thermoresistible__bu RALLEDFVVPAVAQATE-----------------------------
MMAR_4185|M.marinum_M RAMLEEFVAPVVTPFPTRR---------------------------
MUL_4487|M.ulcerans_Agy99 RAMLEEFVAPVVTPFPTRR---------------------------
MAV_1403|M.avium_104 RAMIEEFVVPIVTPVSARG---------------------------
MAB_1938c|M.abscessus_ATCC_199 SEMIERFVYPVLKDATASRVSASATSESTISPARTATFDSSEDDSP
MLBr_01070|M.leprae_Br4923 PLIPDKKVIDTLVHIWLASIYGS-----------------------
: * :