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MPRPGETARRRGRRQGEPVSKEAVLAAAKTRFARDGYEKTTLRAIADDARVDASMVLYLFGSKEQLFREA LRLILDPEVLVAALAGVEGDSSDVGTRMVRTYLGIWEAADSAASMRAMLASATSNPDAHEAFRSFMQDYV LTAVSGVLGGGEQARLRAMLAASSLVGTAMLRYVMRVAPLAELPTEDVVRLVAPTVTRYLTADARELGLP D
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0641 | - | - | 100% (211) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_3298 | - | 3e-25 | 34.69% (196) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_2569 | - | 2e-19 | 35.35% (198) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1711c | - | 1e-29 | 34.93% (209) | hypothetical protein Mb1711c |
| M. gilvum PYR-GCK | Mflv_0253 | - | 2e-85 | 75.71% (210) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1685c | - | 1e-29 | 34.93% (209) | hypothetical protein Rv1685c |
| M. leprae Br4923 | MLBr_02568 | - | 4e-06 | 27.89% (147) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2351c | - | 1e-26 | 34.34% (198) | TetR family transcriptional regulator |
| M. marinum M | MMAR_3397 | - | 7e-30 | 35.45% (189) | putative regulatory protein |
| M. avium 104 | MAV_3088 | - | 3e-29 | 36.49% (211) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_3765 | - | 1e-26 | 32.69% (208) | transcriptional regulator |
| M. thermoresistible (build 8) | TH_3542 | - | 5e-75 | 77.01% (187) | PUTATIVE transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_2781 | - | 2e-27 | 33.00% (200) | hypothetical protein MUL_2781 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0641|M.vanbaalenii_PYR-1 -----------------------------------------MPRPGETAR
TH_3542|M.thermoresistible__bu --------------------------------------------------
Mflv_0253|M.gilvum_PYR-GCK -----------------------------------------MPPPAQTGR
MMAR_3397|M.marinum_M --------------------------------------------------
MAV_3088|M.avium_104 -------------------------------------MTTT---GTTRRR
MSMEG_3765|M.smegmatis_MC2_155 -------------------------------------MTATSDTGRARKR
Mb1711c|M.bovis_AF2122/97 ----------------------------------------MAAPDNSRRR
Rv1685c|M.tuberculosis_H37Rv ----------------------------------------MAAPDNSRRR
MUL_2781|M.ulcerans_Agy99 MQPTTTHPAQARRLRSSGKLLGARDVSAHNKPRNVDNTRGGNAPANERRR
MAB_2351c|M.abscessus_ATCC_199 ---------------------------------------------MSSKR
MLBr_02568|M.leprae_Br4923 -------------------------------------------------M
Mvan_0641|M.vanbaalenii_PYR-1 RRGRRQG-EPVSKEAVLAAAKTRFARDGYEKTTLRAIADDARVDASMVLY
TH_3542|M.thermoresistible__bu ---------------VLAAAKRRFAQDGYEKTTLRAIARDAHVDASMVLY
Mflv_0253|M.gilvum_PYR-GCK RRGRRKG-DPVSRETVLAAAKGRFARDGFEKTTLRAIAEDAGVDASMVLY
MMAR_3397|M.marinum_M -MGRRRG-NPDTRNAIVTTARRLFAESGYEQTSVRDIASAAGVDPALIRH
MAV_3088|M.avium_104 -RGRPAG-SSGSRERILASARELFARNGIRNTSIRAVAAAAGVDSALVHH
MSMEG_3765|M.smegmatis_MC2_155 -PGRPPG-ASDTRDRILASARELFARNGFDKTSIRAVAAGADVDPALVHH
Mb1711c|M.bovis_AF2122/97 -PGRPAG-SSDTRERILSSARELFAHNGIDRTSIRAVAAKAGVDAALVHH
Rv1685c|M.tuberculosis_H37Rv -PGRPAG-SSDTRERILSSARELFAHNGIDRTSIRAVAAKAGVDAALVHH
MUL_2781|M.ulcerans_Agy99 RPGRLRGNSSDTRQRILASARELFASNGIDRTSIRAVAAAADVDAALVHH
MAB_2351c|M.abscessus_ATCC_199 -PGRRPG-TSSARDDILASARKLFSLNGIDKTSIRAIASDAGVDPALVHH
MLBr_02568|M.leprae_Br4923 AGGAKRIPRAVREQQMLDAAVQMFSVNGYHKTSMDAIAAEAQISKPMLYL
:: :* *: .* .*:: :* * :. .::
Mvan_0641|M.vanbaalenii_PYR-1 LFGSKEQLFREALRLILDPEVLVAALAGVEGDSSDVGTRMVRTYLGIWEA
TH_3542|M.thermoresistible__bu LFGSKAELFRESLELILDPEMLVAAMT---GDDGDVGTRMVRVYLQIWES
Mflv_0253|M.gilvum_PYR-GCK LFGSKEALFRESLRLILDPGVLIEALS---GGEADIGTRMVRAYLGVWES
MMAR_3397|M.marinum_M YFGSKAELFRSIVGWPFEADAMSALILS--GDRDELGARLTRVFLEAWER
MAV_3088|M.avium_104 YFGTKEKLFAAAVQIPIDPMQVIGPLR--EVPVDDLGYALPSMLLPLWDS
MSMEG_3765|M.smegmatis_MC2_155 YFGTKTQLFAAAIHIPIDPLEVIGPLR--EVPVEQIGHTLPRLLLPLWDS
Mb1711c|M.bovis_AF2122/97 YFGTKQQLFAAAIHIPIDPMVIIGPIR--EAPVEELGYKLPSLLLPIWDS
Rv1685c|M.tuberculosis_H37Rv YFGTKQQLFAAAIHIPIDPMVIIGPIR--EAPVEELGYKLPSLLLPIWDS
MUL_2781|M.ulcerans_Agy99 YFGTKQQLFAAAIHLPIDPKLVLKRMQ--NTPTAELGFALPSMLLPMWDS
MAB_2351c|M.abscessus_ATCC_199 YFGTKLDLFREVVQLPVDPSVVLQPLR--DVPVDELGVTIPRLIIALWDS
MLBr_02568|M.leprae_Br4923 YYGSKEDLFGACLNREMSRFIAMVRAD--IDFTQSPKDLLRNTIVSFLRY
:*:* ** : .. . : :
Mvan_0641|M.vanbaalenii_PYR-1 ADSAASMRAMLASATSNPDAHEAFRSFMQDYVLTAVSGVLG-GGEQARLR
TH_3542|M.thermoresistible__bu PDTGPTIRAMLQSATSNTDAREAFRSFLREYLLTAVSGVLG-GGEQARLR
Mflv_0253|M.gilvum_PYR-GCK PESAESMRTMLASATSNPDAREAFRGFIQDYVLAAVVGTLG-GDDRARLR
MMAR_3397|M.marinum_M PESRAPLLAILRGAATHEESTTLVRQFFQDQMYPQLAQPLP-GPD-TELR
MAV_3088|M.avium_104 -EVGAAFIATLRSILAG-EEISLFRTFIQDVIGVEVGPRVDNPAGSGVIR
MSMEG_3765|M.smegmatis_MC2_155 -ELGKGFIATLRSILAG-NDVSLVRSFLQEVIVGEVGSRVDNPAGSGRIR
Mb1711c|M.bovis_AF2122/97 -ELGAGLIATLRSLISG-SDVGLARSFLEEVVTVELGSRVDNPPGTGKIR
Rv1685c|M.tuberculosis_H37Rv -ELGAGLIATLRSLISG-SDVGLARSFLEEVVTVELGSRVDNPPGTGKIR
MUL_2781|M.ulcerans_Agy99 -ELGTGLIASLRSLFGG-GDVDLARSFLQEVVTAEMASLVDNPAGTGMIR
MAB_2351c|M.abscessus_ATCC_199 -ELGANMLAVFRSALTG-ADDGLVRVFFREVLVNIIAERVDSPPGSGVLR
MLBr_02568|M.leprae_Br4923 IDANRASWIVMYIQAMSLPAFAQTVREARDQITELVAGLMRVGTRSSRPD
: : .: : : :
Mvan_0641|M.vanbaalenii_PYR-1 AMLAASSLVGTAMLRYVMRVAPLAELPTEDVVRLVAPTVTRYLTADAREL
TH_3542|M.thermoresistible__bu AELAATGLVGTAMLRYIMRVPPLAELSTEEVVRMLAPTVNRYLTADADEL
Mflv_0253|M.gilvum_PYR-GCK AMLAASSLVGTAMMRYLMEIPPLSELATEDVIRLVAPTVTRYLTAPADEL
MMAR_3397|M.marinum_M IDLAMAQLLGIAYLRHVLRLEPIASTPLEEVVARVTPTIIAHLEPSRLDK
MAV_3088|M.avium_104 IQFVASQLVGVVMARYILELEPFASLPPEQIAATIAPNLQRYLTGDLPDG
MSMEG_3765|M.smegmatis_MC2_155 VQYVASQLVGVVMARYILELEPFKSLPVEQIAETIGPNLQRYLTGELPGF
Mb1711c|M.bovis_AF2122/97 TQFVASQLMGVVMARYIVRIEPFASLPAEQIVQTIAPNLQRYLTGELPDD
Rv1685c|M.tuberculosis_H37Rv TQFVASQLMGVVMARYIVRIEPFASLPAEQIVQTIAPNLQRYLTGELPDD
MUL_2781|M.ulcerans_Agy99 AQLVASQLLGVVMARYILQIGPFASMPAEDIARAIAPNLQRYLTGEI---
MAB_2351c|M.abscessus_ATCC_199 AEFAITQMAGILVGRYIMAIEPLASLTAEQIALTVGPNIQRYLTGALPSI
MLBr_02568|M.leprae_Br4923 HEYEIMAGALVGAGEAMATRLTTGDIAVDEAAELMINLFWHGLKGAPADR
. : . . . :: : . *
Mvan_0641|M.vanbaalenii_PYR-1 GLPD------
TH_3542|M.thermoresistible__bu GLPSSLTAGS
Mflv_0253|M.gilvum_PYR-GCK GLPG------
MMAR_3397|M.marinum_M AADR------
MAV_3088|M.avium_104 LAP-------
MSMEG_3765|M.smegmatis_MC2_155 GALD------
Mb1711c|M.bovis_AF2122/97 LAP-------
Rv1685c|M.tuberculosis_H37Rv LAP-------
MUL_2781|M.ulcerans_Agy99 ----------
MAB_2351c|M.abscessus_ATCC_199 TP--------
MLBr_02568|M.leprae_Br4923 DFGPSIVAG-