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MQPTTTHPAQARRLRSSGKLLGARDVSAHNKPRNVDNTRGGNAPANERRRRPGRLRGNSSDTRQRILASA RELFASNGIDRTSIRAVAAAADVDAALVHHYFGTKQQLFAAAIHLPIDPKLVLKRMQNTPTAELGFALPS MLLPMWDSELGTGLIASLRSLFGGGDVDLARSFLQEVVTAEMASLVDNPAGTGMIRAQLVASQLLGVVMA RYILQIGPFASMPAEDIARAIAPNLQRYLTGEI
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_2781 | - | - | 100% (243) | hypothetical protein MUL_2781 |
| M. ulcerans Agy99 | MUL_1664 | - | 1e-69 | 67.01% (194) | hypothetical protein MUL_1664 |
| M. ulcerans Agy99 | MUL_3981 | - | 1e-28 | 39.20% (199) | putative regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1711c | - | 2e-78 | 73.63% (201) | hypothetical protein Mb1711c |
| M. gilvum PYR-GCK | Mflv_0253 | - | 2e-25 | 33.67% (199) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1685c | - | 2e-78 | 73.63% (201) | hypothetical protein Rv1685c |
| M. leprae Br4923 | MLBr_02568 | - | 4e-06 | 35.29% (51) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2351c | - | 3e-52 | 50.00% (194) | TetR family transcriptional regulator |
| M. marinum M | MMAR_3548 | - | 1e-132 | 98.77% (243) | hypothetical protein MMAR_3548 |
| M. avium 104 | MAV_3088 | - | 1e-67 | 64.62% (195) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_3765 | - | 1e-71 | 68.21% (195) | transcriptional regulator |
| M. thermoresistible (build 8) | TH_3542 | - | 2e-24 | 32.40% (179) | PUTATIVE transcriptional regulator, TetR family |
| M. vanbaalenii PYR-1 | Mvan_3298 | - | 4e-66 | 61.11% (198) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0253|M.gilvum_PYR-GCK --------------------------------------------------
TH_3542|M.thermoresistible__bu --------------------------------------------------
MUL_2781|M.ulcerans_Agy99 ---------------------MQPTTTHPAQARRLRSSGKLLGARDVSAH
MMAR_3548|M.marinum_M MIDKAPFRGARTVLHSTTTASMQPTTTHPAQARRLRSSGELLGARDVSAH
Mb1711c|M.bovis_AF2122/97 --------------------------------------------------
Rv1685c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_3765|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_3298|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_3088|M.avium_104 --------------------------------------------------
MAB_2351c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_02568|M.leprae_Br4923 --------------------------------------------------
Mflv_0253|M.gilvum_PYR-GCK ------------MPPPAQTGRRRGRRKG-DPVSRETVLAAAKGRFARDGF
TH_3542|M.thermoresistible__bu ------------------------------------VLAAAKRRFAQDGY
MUL_2781|M.ulcerans_Agy99 NKPRNVDNTRGGNAPANERRRRPGRLRGNSSDTRQRILASARELFASNGI
MMAR_3548|M.marinum_M NKPRNVDNTRGGNAPANERRRRPGRPRGNSSDTRQRILASARELFASNGI
Mb1711c|M.bovis_AF2122/97 ------------MAAPDNSRRRPGRPAG-SSDTRERILSSARELFAHNGI
Rv1685c|M.tuberculosis_H37Rv ------------MAAPDNSRRRPGRPAG-SSDTRERILSSARELFAHNGI
MSMEG_3765|M.smegmatis_MC2_155 ---------MTATSDTGRARKRPGRPPG-ASDTRDRILASARELFARNGF
Mvan_3298|M.vanbaalenii_PYR-1 ---------MTTNAD----RKRPGRPPG-TSDTRDRILECARELFARNGI
MAV_3088|M.avium_104 ---------MTTTGTT---RRRRGRPAG-SSGSRERILASARELFARNGI
MAB_2351c|M.abscessus_ATCC_199 ---------MS--------SKRPGRRPG-TSSARDDILASARKLFSLNGI
MLBr_02568|M.leprae_Br4923 --------------------MAGGAKRIPRAVREQQMLDAAVQMFSVNGY
:* .* *: :*
Mflv_0253|M.gilvum_PYR-GCK EKTTLRAIAEDAGVDASMVLYLFGSKEALFRESLRLILDPGVLIEALSGG
TH_3542|M.thermoresistible__bu EKTTLRAIARDAHVDASMVLYLFGSKAELFRESLELILDPEMLVAAMTGD
MUL_2781|M.ulcerans_Agy99 DRTSIRAVAAAADVDAALVHHYFGTKQQLFAAAIHLPIDPKLVLKRMQNT
MMAR_3548|M.marinum_M DRTSIRAVAAAADVDAALVHHYFGTKQQLFAAAIHLPIDPKLVLKRMQNT
Mb1711c|M.bovis_AF2122/97 DRTSIRAVAAKAGVDAALVHHYFGTKQQLFAAAIHIPIDPMVIIGPIREA
Rv1685c|M.tuberculosis_H37Rv DRTSIRAVAAKAGVDAALVHHYFGTKQQLFAAAIHIPIDPMVIIGPIREA
MSMEG_3765|M.smegmatis_MC2_155 DKTSIRAVAAGADVDPALVHHYFGTKTQLFAAAIHIPIDPLEVIGPLREV
Mvan_3298|M.vanbaalenii_PYR-1 TNTSIRSIAAGAGVDPALVHHYFGTKTQLFAAAIEIPIDPMSIIGPLKEV
MAV_3088|M.avium_104 RNTSIRAVAAAAGVDSALVHHYFGTKEKLFAAAVQIPIDPMQVIGPLREV
MAB_2351c|M.abscessus_ATCC_199 DKTSIRAIASDAGVDPALVHHYFGTKLDLFREVVQLPVDPSVVLQPLRDV
MLBr_02568|M.leprae_Br4923 HKTSMDAIAAEAQISKPMLYLYYGSKEDLFGACLNREMSRFIAMVRADID
.*:: ::* * :. .:: :*:* ** :. :. :
Mflv_0253|M.gilvum_PYR-GCK -EADIGTRMVRAYLGVWESPESAESMRTMLASATSNPDAREAFRGFIQDY
TH_3542|M.thermoresistible__bu -DGDVGTRMVRVYLQIWESPDTGPTIRAMLQSATSNTDAREAFRSFLREY
MUL_2781|M.ulcerans_Agy99 PTAELGFALPSMLLPMWDS-ELGTGLIASLRSLFGG-GDVDLARSFLQEV
MMAR_3548|M.marinum_M PTAELGFALPSMLLPMWDS-ELGTGLIASLRSLFGG-GDVDLARSFLQEV
Mb1711c|M.bovis_AF2122/97 PVEELGYKLPSLLLPIWDS-ELGAGLIATLRSLISG-SDVGLARSFLEEV
Rv1685c|M.tuberculosis_H37Rv PVEELGYKLPSLLLPIWDS-ELGAGLIATLRSLISG-SDVGLARSFLEEV
MSMEG_3765|M.smegmatis_MC2_155 PVEQIGHTLPRLLLPLWDS-ELGKGFIATLRSILAG-NDVSLVRSFLQEV
Mvan_3298|M.vanbaalenii_PYR-1 PVDQLGRALPSLLLPLWDS-ELGKGFIATLRSILAG-SDVSMVRSFLQDL
MAV_3088|M.avium_104 PVDDLGYALPSMLLPLWDS-EVGAAFIATLRSILAG-EEISLFRTFIQDV
MAB_2351c|M.abscessus_ATCC_199 PVDELGVTIPRLIIALWDS-ELGANMLAVFRSALTG-ADDGLVRVFFREV
MLBr_02568|M.leprae_Br4923 FTQSPKDLLRNTIVSFLRYIDANRASWIVMYIQAMSLPAFAQTVREARDQ
. : : . : : . .:
Mflv_0253|M.gilvum_PYR-GCK VLAAVVGTLGG-DDRARLRAMLAASSLVGTAMMRYLMEIPPLSELATEDV
TH_3542|M.thermoresistible__bu LLTAVSGVLGG-GEQARLRAELAATGLVGTAMLRYIMRVPPLAELSTEEV
MUL_2781|M.ulcerans_Agy99 VTAEMASLVDNPAGTGMIRAQLVASQLLGVVMARYILQIGPFASMPAEDI
MMAR_3548|M.marinum_M VTAEMASLVDNPAGTGMIRAQLVASQLLGVVMARYILQIEPFASMPAEDI
Mb1711c|M.bovis_AF2122/97 VTVELGSRVDNPPGTGKIRTQFVASQLMGVVMARYIVRIEPFASLPAEQI
Rv1685c|M.tuberculosis_H37Rv VTVELGSRVDNPPGTGKIRTQFVASQLMGVVMARYIVRIEPFASLPAEQI
MSMEG_3765|M.smegmatis_MC2_155 IVGEVGSRVDNPAGSGRIRVQYVASQLVGVVMARYILELEPFKSLPVEQI
Mvan_3298|M.vanbaalenii_PYR-1 IATEVGGRVDDPPGSGRVRVQFVASQLVGIVMARYILELEPFKSLPVEQI
MAV_3088|M.avium_104 IGVEVGPRVDNPAGSGVIRIQFVASQLVGVVMARYILELEPFASLPPEQI
MAB_2351c|M.abscessus_ATCC_199 LVNIIAERVDSPPGSGVLRAEFAITQMAGILVGRYIMAIEPLASLTAEQI
MLBr_02568|M.leprae_Br4923 ITELVAGLMRVGTRSSRPDHEYEIMAGALVGAGEAMATRLTTGDIAVDEA
: : : . . : . .:. ::
Mflv_0253|M.gilvum_PYR-GCK IRLVAPTVTRYLTAPADELGLPG------
TH_3542|M.thermoresistible__bu VRMLAPTVNRYLTADADELGLPSSLTAGS
MUL_2781|M.ulcerans_Agy99 ARAIAPNLQRYLTGEI-------------
MMAR_3548|M.marinum_M ARAIAPNLQRYLTGEI-------------
Mb1711c|M.bovis_AF2122/97 VQTIAPNLQRYLTGELPDDLAP-------
Rv1685c|M.tuberculosis_H37Rv VQTIAPNLQRYLTGELPDDLAP-------
MSMEG_3765|M.smegmatis_MC2_155 AETIGPNLQRYLTGELPGFGALD------
Mvan_3298|M.vanbaalenii_PYR-1 VDTVAPNLQRYLTGELPQFSGD-------
MAV_3088|M.avium_104 AATIAPNLQRYLTGDLPDGLAP-------
MAB_2351c|M.abscessus_ATCC_199 ALTVGPNIQRYLTGALPSITP--------
MLBr_02568|M.leprae_Br4923 AELMINLFWHGLKGAPADRDFGPSIVAG-
: . : *..