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VSKIPPGPRDERGVLSSRILVAARGAFADTGYAGTTIRAVARAADVDPALVYHYFGSKEALLDAATDPPQ RWLQNVARAWTTPVPQLGAALVRLMLDAWADEEIGPVLRAILQTAAHEAATREKLRLVVERSLMGVSQLG VDERDRMLRSGLISSQIMGLAMMRYVWRIEPVASMDDDELVAAVAPNLQRYISDDLG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2569 | - | - | 100% (197) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_3298 | - | 7e-26 | 37.24% (196) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0641 | - | 2e-19 | 35.35% (198) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1711c | - | 1e-25 | 38.97% (195) | hypothetical protein Mb1711c |
| M. gilvum PYR-GCK | Mflv_0253 | - | 4e-22 | 34.00% (200) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1685c | - | 1e-25 | 38.97% (195) | hypothetical protein Rv1685c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2351c | - | 2e-20 | 32.64% (193) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4115 | - | 5e-75 | 68.04% (194) | putative regulatory protein |
| M. avium 104 | MAV_3088 | - | 1e-26 | 38.46% (182) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5282 | - | 1e-74 | 68.02% (197) | transcriptional regulator |
| M. thermoresistible (build 8) | TH_3542 | - | 9e-25 | 35.52% (183) | PUTATIVE transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_3981 | - | 6e-75 | 68.04% (194) | putative regulatory protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4115|M.marinum_M ---MGGRRVKPGPRDEKGVLAAQILSVARDSFAENGSAGTTVRSVARAAD
MUL_3981|M.ulcerans_Agy99 ---MGGRRVKPGPRDEKGVLAAQILSVARDSFAENGSAGTTVRSVARAAD
Mvan_2569|M.vanbaalenii_PYR-1 ---MS--KIPPGPRDERGVLSSRILVAARGAFADTGYAGTTIRAVARAAD
MSMEG_5282|M.smegmatis_MC2_155 -MVKRSARATPGPRDDRGVLAARILAAARETFAESGWAGTTIRAVARAAD
Mb1711c|M.bovis_AF2122/97 MAAPDNSRRRPGRPAGSSDTRERILSSARELFAHNGIDRTSIRAVAAKAG
Rv1685c|M.tuberculosis_H37Rv MAAPDNSRRRPGRPAGSSDTRERILSSARELFAHNGIDRTSIRAVAAKAG
MAV_3088|M.avium_104 MTTTGTTRRRRGRPAGSSGSRERILASARELFARNGIRNTSIRAVAAAAG
MAB_2351c|M.abscessus_ATCC_199 MSS-----KRPGRRPGTSSARDDILASARKLFSLNGIDKTSIRAIASDAG
Mflv_0253|M.gilvum_PYR-GCK MPPPAQTGRRRGRRKGDPVSRETVLAAAKGRFARDGFEKTTLRAIAEDAG
TH_3542|M.thermoresistible__bu -----------------------VLAAAKRRFAQDGYEKTTLRAIARDAH
:* *: *: * *::*::* *
MMAR_4115|M.marinum_M VDPSLIYHYFGSKEGLLDAATTPPQRWLDTVAETWTTPKADLGRRLLQTL
MUL_3981|M.ulcerans_Agy99 VDPSLIYHYFGSKEGLLDAATMPPQRWLDTVAETWTTPKADLGRRLLQTL
Mvan_2569|M.vanbaalenii_PYR-1 VDPALVYHYFGSKEALLDAATDPPQRWLQNVARAWTTPVPQLGAALVRLM
MSMEG_5282|M.smegmatis_MC2_155 VDPALVYHYYGSKEGLLDAATDPPQKWLDAVVATWQAPVGDTGRAVLRLL
Mb1711c|M.bovis_AF2122/97 VDAALVHHYFGTKQQLFAAAIHIPIDPMVIIGPIREAPVEELGYKLPSLL
Rv1685c|M.tuberculosis_H37Rv VDAALVHHYFGTKQQLFAAAIHIPIDPMVIIGPIREAPVEELGYKLPSLL
MAV_3088|M.avium_104 VDSALVHHYFGTKEKLFAAAVQIPIDPMQVIGPLREVPVDDLGYALPSML
MAB_2351c|M.abscessus_ATCC_199 VDPALVHHYFGTKLDLFREVVQLPVDPSVVLQPLRDVPVDELGVTIPRLI
Mflv_0253|M.gilvum_PYR-GCK VDASMVLYLFGSKEALFRESLRLILDPGVLIEALSGG-EADIGTRMVRAY
TH_3542|M.thermoresistible__bu VDASMVLYLFGSKAELFRESLELILDPEMLVAAMTGD-DGDVGTRMVRVY
**.::: : :*:* *: : : * :
MMAR_4115|M.marinum_M LDSWADDEIGPSLRAILLTAAHEDATRLKLRRIVESSLIG-VSQLDTD-E
MUL_3981|M.ulcerans_Agy99 LDSWADDEIGPSLRAILLTAAHEDATRLKLRRIVESSLIG-VSQLDTD-E
Mvan_2569|M.vanbaalenii_PYR-1 LDAWADEEIGPVLRAILQTAAHEAATREKLRLVVERSLMG-VSQLGVD-E
MSMEG_5282|M.smegmatis_MC2_155 LDSWADDEVGPVLRAILQTAAHEPTTHEKLRKVVERSLIGVIATMGDD-E
Mb1711c|M.bovis_AF2122/97 LPIWDS-ELGAGLIATLRSLISG-SDVGLARSFLEEVVTVELGSRVDNPP
Rv1685c|M.tuberculosis_H37Rv LPIWDS-ELGAGLIATLRSLISG-SDVGLARSFLEEVVTVELGSRVDNPP
MAV_3088|M.avium_104 LPLWDS-EVGAAFIATLRSILAG-EEISLFRTFIQDVIGVEVGPRVDNPA
MAB_2351c|M.abscessus_ATCC_199 IALWDS-ELGANMLAVFRSALTG-ADDGLVRVFFREVLVNIIAERVDSPP
Mflv_0253|M.gilvum_PYR-GCK LGVWESPESAESMRTMLASATSNPDAREAFRGFIQDYVLAAVVGTLGG-D
TH_3542|M.thermoresistible__bu LQIWESPDTGPTIRAMLQSATSNTDAREAFRSFLREYLLTAVSGVLGG-G
: * . : . : : : : * ... : : .
MMAR_4115|M.marinum_M DDRLTRSGLIASQLIGLAMTRYVWQIEPIASMSDSEVLAAITPNLQRYID
MUL_3981|M.ulcerans_Agy99 DDRLTRSGLIASQLIGLAMTRYVWQIEPIASMSDSEVLAAITPNLQRYID
Mvan_2569|M.vanbaalenii_PYR-1 RDRMLRSGLISSQIMGLAMMRYVWRIEPVASMDDDELVAAVAPNLQRYIS
MSMEG_5282|M.smegmatis_MC2_155 RVRRTRAGLVASQTIGFALMRYVWRIEPVASMREDEVLDAVGPTLQRYID
Mb1711c|M.bovis_AF2122/97 GTGKIRTQFVASQLMGVVMARYIVRIEPFASLPAEQIVQTIAPNLQRYLT
Rv1685c|M.tuberculosis_H37Rv GTGKIRTQFVASQLMGVVMARYIVRIEPFASLPAEQIVQTIAPNLQRYLT
MAV_3088|M.avium_104 GSGVIRIQFVASQLVGVVMARYILELEPFASLPPEQIAATIAPNLQRYLT
MAB_2351c|M.abscessus_ATCC_199 GSGVLRAEFAITQMAGILVGRYIMAIEPLASLTAEQIALTVGPNIQRYLT
Mflv_0253|M.gilvum_PYR-GCK DRARLRAMLAASSLVGTAMMRYLMEIPPLSELATEDVIRLVAPTVTRYLT
TH_3542|M.thermoresistible__bu EQARLRAELAATGLVGTAMLRYIMRVPPLAELSTEEVVRMLAPTVNRYLT
* : : * : **: : *.:.: .:: : *.: **:
MMAR_4115|M.marinum_M GDLHPTKKSPAQRPRRTRRP
MUL_3981|M.ulcerans_Agy99 GDLHPTKNSPAQRPRRTRRP
Mvan_2569|M.vanbaalenii_PYR-1 DDLG----------------
MSMEG_5282|M.smegmatis_MC2_155 GDIGAAGQIRTGFDTA----
Mb1711c|M.bovis_AF2122/97 GELPDDLAP-----------
Rv1685c|M.tuberculosis_H37Rv GELPDDLAP-----------
MAV_3088|M.avium_104 GDLPDGLAP-----------
MAB_2351c|M.abscessus_ATCC_199 GALPS-ITP-----------
Mflv_0253|M.gilvum_PYR-GCK APADELGLPG----------
TH_3542|M.thermoresistible__bu ADADELGLPSSLTAGS----