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M. thermoresistible (build 8) TH_3542 (-)

annotation: transcriptional regulator, TetR family
coordinates: 4628303 - 4628878
length: 192

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3542--100% (192)transcriptional regulator, TetR family

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1711c-3e-2433.52% (179) hypothetical protein Mb1711c
M. gilvum PYR-GCKMflv_0253-1e-7069.57% (184) TetR family transcriptional regulator
M. tuberculosis H37RvRv1685c-3e-2433.52% (179) hypothetical protein Rv1685c
M. leprae Br4923MLBr_02568-0.000140.91% (44) putative TetR-family transcriptional regulator
M. abscessus ATCC 19977MAB_2351c-6e-2535.75% (179) TetR family transcriptional regulator
M. marinum MMMAR_3397-8e-2734.29% (175) putative regulatory protein
M. avium 104MAV_3088-9e-2130.73% (179) transcriptional regulator, TetR family protein
M. smegmatis MC2 155MSMEG_1700-1e-2634.86% (175) TetR-family protein transcriptional regulator
M. ulcerans Agy99MUL_2781-2e-2432.40% (179) hypothetical protein MUL_2781
M. vanbaalenii PYR-1Mvan_0641-6e-7577.01% (187) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mb1711c|M.bovis_AF2122/97           ----------------------------------------MAAPDNSRRR
Rv1685c|M.tuberculosis_H37Rv        ----------------------------------------MAAPDNSRRR
MUL_2781|M.ulcerans_Agy99           MQPTTTHPAQARRLRSSGKLLGARDVSAHNKPRNVDNTRGGNAPANERRR
MAV_3088|M.avium_104                ----------------------------------------MTTTGTTRRR
MAB_2351c|M.abscessus_ATCC_199      ---------------------------------------------MSSKR
Mflv_0253|M.gilvum_PYR-GCK          -----------------------------------------MPPPAQTGR
Mvan_0641|M.vanbaalenii_PYR-1       -----------------------------------------MPRPGETAR
TH_3542|M.thermoresistible__bu      --------------------------------------------------
MMAR_3397|M.marinum_M               --------------------------------------------------
MSMEG_1700|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_02568|M.leprae_Br4923          -------------------------------------------------M
                                                                                      

Mb1711c|M.bovis_AF2122/97           -PGRPAG-SSDTRERILSSARELFAHNGIDRTSIRAVAAKAGVDAALVHH
Rv1685c|M.tuberculosis_H37Rv        -PGRPAG-SSDTRERILSSARELFAHNGIDRTSIRAVAAKAGVDAALVHH
MUL_2781|M.ulcerans_Agy99           RPGRLRGNSSDTRQRILASARELFASNGIDRTSIRAVAAAADVDAALVHH
MAV_3088|M.avium_104                -RGRPAG-SSGSRERILASARELFARNGIRNTSIRAVAAAAGVDSALVHH
MAB_2351c|M.abscessus_ATCC_199      -PGRRPG-TSSARDDILASARKLFSLNGIDKTSIRAIASDAGVDPALVHH
Mflv_0253|M.gilvum_PYR-GCK          RRGRRKG-DPVSRETVLAAAKGRFARDGFEKTTLRAIAEDAGVDASMVLY
Mvan_0641|M.vanbaalenii_PYR-1       RRGRRQG-EPVSKEAVLAAAKTRFARDGYEKTTLRAIADDARVDASMVLY
TH_3542|M.thermoresistible__bu      ---------------VLAAAKRRFAQDGYEKTTLRAIARDAHVDASMVLY
MMAR_3397|M.marinum_M               -MGRRRG-NPDTRNAIVTTARRLFAESGYEQTSVRDIASAAGVDPALIRH
MSMEG_1700|M.smegmatis_MC2_155      ---MRRS-AAETKSVILAAARERFAADGYERATIRSIAADASIDPSMVMR
MLBr_02568|M.leprae_Br4923          AGGAKRIPRAVREQQMLDAAVQMFSVNGYHKTSMDAIAAEAQISKPMLYL
                                                   :: :*   *: .*  .:::  :*  * :. .::  

Mb1711c|M.bovis_AF2122/97           YFGTKQQLFAAAIHIPIDPMVIIGPIREAP--VEELGYKLPSLLLPIWDS
Rv1685c|M.tuberculosis_H37Rv        YFGTKQQLFAAAIHIPIDPMVIIGPIREAP--VEELGYKLPSLLLPIWDS
MUL_2781|M.ulcerans_Agy99           YFGTKQQLFAAAIHLPIDPKLVLKRMQNTP--TAELGFALPSMLLPMWDS
MAV_3088|M.avium_104                YFGTKEKLFAAAVQIPIDPMQVIGPLREVP--VDDLGYALPSMLLPLWDS
MAB_2351c|M.abscessus_ATCC_199      YFGTKLDLFREVVQLPVDPSVVLQPLRDVP--VDELGVTIPRLIIALWDS
Mflv_0253|M.gilvum_PYR-GCK          LFGSKEALFRESLRLILDPGVLIEALSGGE---ADIGTRMVRAYLGVWES
Mvan_0641|M.vanbaalenii_PYR-1       LFGSKEQLFREALRLILDPEVLVAALAGVEGDSSDVGTRMVRTYLGIWEA
TH_3542|M.thermoresistible__bu      LFGSKAELFRESLELILDPEMLVAAMTGDD---GDVGTRMVRVYLQIWES
MMAR_3397|M.marinum_M               YFGSKAELFRSIVGWPFEADAMSALILSGD--RDELGARLTRVFLEAWER
MSMEG_1700|M.smegmatis_MC2_155      YFGNKERLFAAAAEFDLELPDL-ALVP-----REEIGATLAGHFLERWER
MLBr_02568|M.leprae_Br4923          YYGSKEDLFGACLNREMS--RFIAMVRADIDFTQSPKDLLRNTIVSFLRY
                                     :*.*  **       ..   .   :        .    :    :     

Mb1711c|M.bovis_AF2122/97           ELG--AGLIATLRSLISGSDVGLARSFLEEVVTVELGSRVDNPPGTGKIR
Rv1685c|M.tuberculosis_H37Rv        ELG--AGLIATLRSLISGSDVGLARSFLEEVVTVELGSRVDNPPGTGKIR
MUL_2781|M.ulcerans_Agy99           ELG--TGLIASLRSLFGGGDVDLARSFLQEVVTAEMASLVDNPAGTGMIR
MAV_3088|M.avium_104                EVG--AAFIATLRSILAGEEISLFRTFIQDVIGVEVGPRVDNPAGSGVIR
MAB_2351c|M.abscessus_ATCC_199      ELG--ANMLAVFRSALTGADDGLVRVFFREVLVNIIAERVDSPPGSGVLR
Mflv_0253|M.gilvum_PYR-GCK          PESA-ESMRTMLASATSNPDAREAFRGFIQDYVLAAVVGTLGGDDRARLR
Mvan_0641|M.vanbaalenii_PYR-1       ADSA-ASMRAMLASATSNPDAHEAFRSFMQDYVLTAVSGVLGGGEQARLR
TH_3542|M.thermoresistible__bu      PDTG-PTIRAMLQSATSNTDAREAFRSFLREYLLTAVSGVLGGGEQARLR
MMAR_3397|M.marinum_M               PESR-APLLAILRGAATHEESTTLVRQFFQDQMYPQLAQPLPG-PDTELR
MSMEG_1700|M.smegmatis_MC2_155      DE----ALLILLRAGVTNEAVAERMRTIFAAQLAPVIAKLTGGAPDAPVR
MLBr_02568|M.leprae_Br4923          IDANRASWIVMYIQAMSLPAFAQTVREARDQITELVAGLMRVGTRSSRPD
                                                                                      

Mb1711c|M.bovis_AF2122/97           TQFVASQLMGVVMARYIVRIEPFASLPAEQIVQTIAPNLQRYLTGELPDD
Rv1685c|M.tuberculosis_H37Rv        TQFVASQLMGVVMARYIVRIEPFASLPAEQIVQTIAPNLQRYLTGELPDD
MUL_2781|M.ulcerans_Agy99           AQLVASQLLGVVMARYILQIGPFASMPAEDIARAIAPNLQRYLTGEI---
MAV_3088|M.avium_104                IQFVASQLVGVVMARYILELEPFASLPPEQIAATIAPNLQRYLTGDLPDG
MAB_2351c|M.abscessus_ATCC_199      AEFAITQMAGILVGRYIMAIEPLASLTAEQIALTVGPNIQRYLTGALPS-
Mflv_0253|M.gilvum_PYR-GCK          AMLAASSLVGTAMMRYLMEIPPLSELATEDVIRLVAPTVTRYLTAPADEL
Mvan_0641|M.vanbaalenii_PYR-1       AMLAASSLVGTAMLRYVMRVAPLAELPTEDVVRLVAPTVTRYLTADAREL
TH_3542|M.thermoresistible__bu      AELAATGLVGTAMLRYIMRVPPLAELSTEEVVRMLAPTVNRYLTADADEL
MMAR_3397|M.marinum_M               IDLAMAQLLGIAYLRHVLRLEPIASTPLEEVVARVTPTIIAHLEPSRLDK
MSMEG_1700|M.smegmatis_MC2_155      ASLAASQVLGMALCRYVLAFPPLVDMSRDGVVAWIGPTLQRYLVG-----
MLBr_02568|M.leprae_Br4923          HEYEIMAGALVGAGEAMATRLTTGDIAVDEAAELMINLFWHGLKGAPADR
                                                  . :    .  . . :     :   .   *       

Mb1711c|M.bovis_AF2122/97           LAP-------
Rv1685c|M.tuberculosis_H37Rv        LAP-------
MUL_2781|M.ulcerans_Agy99           ----------
MAV_3088|M.avium_104                LAP-------
MAB_2351c|M.abscessus_ATCC_199      ITP-------
Mflv_0253|M.gilvum_PYR-GCK          GLPG------
Mvan_0641|M.vanbaalenii_PYR-1       GLPD------
TH_3542|M.thermoresistible__bu      GLPSSLTAGS
MMAR_3397|M.marinum_M               AADR------
MSMEG_1700|M.smegmatis_MC2_155      ----------
MLBr_02568|M.leprae_Br4923          DFGPSIVAG-