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SSKRPGRRPGTSSARDDILASARKLFSLNGIDKTSIRAIASDAGVDPALVHHYFGTKLDLFREVVQLPVD PSVVLQPLRDVPVDELGVTIPRLIIALWDSELGANMLAVFRSALTGADDGLVRVFFREVLVNIIAERVDS PPGSGVLRAEFAITQMAGILVGRYIMAIEPLASLTAEQIALTVGPNIQRYLTGALPSITP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2351c | - | - | 100% (201) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2885 | - | 4e-16 | 30.77% (195) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4776c | - | 2e-10 | 28.74% (167) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1711c | - | 1e-62 | 54.59% (196) | hypothetical protein Mb1711c |
| M. gilvum PYR-GCK | Mflv_0253 | - | 4e-26 | 34.36% (195) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1685c | - | 2e-62 | 54.59% (196) | hypothetical protein Rv1685c |
| M. leprae Br4923 | MLBr_02568 | - | 1e-05 | 43.18% (44) | putative TetR-family transcriptional regulator |
| M. marinum M | MMAR_2484 | - | 6e-58 | 49.48% (194) | hypothetical protein MMAR_2484 |
| M. avium 104 | MAV_3088 | - | 1e-58 | 54.64% (194) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_3765 | - | 7e-64 | 57.73% (194) | transcriptional regulator |
| M. thermoresistible (build 8) | TH_3542 | - | 5e-25 | 35.75% (179) | PUTATIVE transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_1664 | - | 5e-55 | 49.21% (189) | hypothetical protein MUL_1664 |
| M. vanbaalenii PYR-1 | Mvan_3298 | - | 4e-61 | 54.31% (197) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0253|M.gilvum_PYR-GCK MPPPAQT---GRRRGRRKGDPVSRETVLAAAKGRFARDGFEKTTLRAIAE
TH_3542|M.thermoresistible__bu --------------------------VLAAAKRRFAQDGYEKTTLRAIAR
MSMEG_3765|M.smegmatis_MC2_155 MTATSDTGRARKRPGRPPGASDTRDRILASARELFARNGFDKTSIRAVAA
Mvan_3298|M.vanbaalenii_PYR-1 MTTNAD----RKRPGRPPGTSDTRDRILECARELFARNGITNTSIRSIAA
MAV_3088|M.avium_104 MTTTGTT---RRRRGRPAGSSGSRERILASARELFARNGIRNTSIRAVAA
Mb1711c|M.bovis_AF2122/97 MAAPDNS---RRRPGRPAGSSDTRERILSSARELFAHNGIDRTSIRAVAA
Rv1685c|M.tuberculosis_H37Rv MAAPDNS---RRRPGRPAGSSDTRERILSSARELFAHNGIDRTSIRAVAA
MMAR_2484|M.marinum_M METTNTG---RRRPGRPTGTSNTREHILTCARELFALNGLDRTSVRSVAA
MUL_1664|M.ulcerans_Agy99 METTNTG---RRRPGRPTGTSNTREHILTCARELFALNGLDRTSVRSVAA
MAB_2351c|M.abscessus_ATCC_199 MS--------SKRPGRRPGTSSARDDILASARKLFSLNGIDKTSIRAIAS
MLBr_02568|M.leprae_Br4923 ----------MAGGAKRIPRAVREQQMLDAAVQMFSVNGYHKTSMDAIAA
:* .* *: :* .*:: ::*
Mflv_0253|M.gilvum_PYR-GCK DAGVDASMVLYLFGSKEALFRESLRLILDPGVLIEALSGG-EADIGTRMV
TH_3542|M.thermoresistible__bu DAHVDASMVLYLFGSKAELFRESLELILDPEMLVAAMTGD-DGDVGTRMV
MSMEG_3765|M.smegmatis_MC2_155 GADVDPALVHHYFGTKTQLFAAAIHIPIDPLEVIGPLREVPVEQIGHTLP
Mvan_3298|M.vanbaalenii_PYR-1 GAGVDPALVHHYFGTKTQLFAAAIEIPIDPMSIIGPLKEVPVDQLGRALP
MAV_3088|M.avium_104 AAGVDSALVHHYFGTKEKLFAAAVQIPIDPMQVIGPLREVPVDDLGYALP
Mb1711c|M.bovis_AF2122/97 KAGVDAALVHHYFGTKQQLFAAAIHIPIDPMVIIGPIREAPVEELGYKLP
Rv1685c|M.tuberculosis_H37Rv KAGVDAALVHHYFGTKQQLFAAAIHIPIDPMVIIGPIREAPVEELGYKLP
MMAR_2484|M.marinum_M AAGVDASLVHHYYGTKQQLFAAAIQIPIDPTVVLEQIVETPVDELGLKLP
MUL_1664|M.ulcerans_Agy99 AAGVDASLVHHYYGTKQQLFAAAIQIPIDPTVVLEQIVETPVDELGLKIP
MAB_2351c|M.abscessus_ATCC_199 DAGVDPALVHHYFGTKLDLFREVVQLPVDPSVVLQPLRDVPVDELGVTIP
MLBr_02568|M.leprae_Br4923 EAQISKPMLYLYYGSKEDLFGACLNREMSRFIAMVRADIDFTQSPKDLLR
* :. .:: :*:* ** :. :. : . :
Mflv_0253|M.gilvum_PYR-GCK RAYLGVWESPESAESMRTMLASATSNPDAREAFRGFIQDYVLAAVVGTLG
TH_3542|M.thermoresistible__bu RVYLQIWESPDTGPTIRAMLQSATSNTDAREAFRSFLREYLLTAVSGVLG
MSMEG_3765|M.smegmatis_MC2_155 RLLLPLWDS-ELGKGFIATLRSILAGNDV-SLVRSFLQEVIVGEVGSRVD
Mvan_3298|M.vanbaalenii_PYR-1 SLLLPLWDS-ELGKGFIATLRSILAGSDV-SMVRSFLQDLIATEVGGRVD
MAV_3088|M.avium_104 SMLLPLWDS-EVGAAFIATLRSILAGEEI-SLFRTFIQDVIGVEVGPRVD
Mb1711c|M.bovis_AF2122/97 SLLLPIWDS-ELGAGLIATLRSLISGSDV-GLARSFLEEVVTVELGSRVD
Rv1685c|M.tuberculosis_H37Rv SLLLPIWDS-ELGAGLIATLRSLISGSDV-GLARSFLEEVVTVELGSRVD
MMAR_2484|M.marinum_M SVLLPLWDS-ELGTGLVSTLRALMAGTES-NLARSFLQEVVTSEVGSRVD
MUL_1664|M.ulcerans_Agy99 SVPLPLWDS-ELSTGLVATLRALMAGTES-NLARSFLQEVVTSEVGSRVD
MAB_2351c|M.abscessus_ATCC_199 RLIIALWDS-ELGANMLAVFRSALTGADD-GLVRVFFREVLVNIIAERVD
MLBr_02568|M.leprae_Br4923 NTIVSFLRYIDANRASWIVMYIQAMSLPAFAQTVREARDQITELVAGLMR
: . : : . .: : : :
Mflv_0253|M.gilvum_PYR-GCK G-DDRARLRAMLAASSLVGTAMMRYLMEIPPLSELATEDVIRLVAPTVTR
TH_3542|M.thermoresistible__bu G-GEQARLRAELAATGLVGTAMLRYIMRVPPLAELSTEEVVRMLAPTVNR
MSMEG_3765|M.smegmatis_MC2_155 NPAGSGRIRVQYVASQLVGVVMARYILELEPFKSLPVEQIAETIGPNLQR
Mvan_3298|M.vanbaalenii_PYR-1 DPPGSGRVRVQFVASQLVGIVMARYILELEPFKSLPVEQIVDTVAPNLQR
MAV_3088|M.avium_104 NPAGSGVIRIQFVASQLVGVVMARYILELEPFASLPPEQIAATIAPNLQR
Mb1711c|M.bovis_AF2122/97 NPPGTGKIRTQFVASQLMGVVMARYIVRIEPFASLPAEQIVQTIAPNLQR
Rv1685c|M.tuberculosis_H37Rv NPPGTGKIRTQFVASQLMGVVMARYIVRIEPFASLPAEQIVQTIAPNLQR
MMAR_2484|M.marinum_M SPTGTGRIRAQFVASQLLGVVMARHIVKIEPFASLPADQVAQAIAPTLQR
MUL_1664|M.ulcerans_Agy99 SPTGTGRIRAQFVTSQLLGVVMARHIVKIEPFASLPADQVAQAIAPTLQR
MAB_2351c|M.abscessus_ATCC_199 SPPGSGVLRAEFAITQMAGILVGRYIMAIEPLASLTAEQIALTVGPNIQR
MLBr_02568|M.leprae_Br4923 VGTRSSRPDHEYEIMAGALVGAGEAMATRLTTGDIAVDEAAELMINLFWH
. . : . .:. :: : . :
Mflv_0253|M.gilvum_PYR-GCK YLTAPADELGLPG------
TH_3542|M.thermoresistible__bu YLTADADELGLPSSLTAGS
MSMEG_3765|M.smegmatis_MC2_155 YLTGELPGFGALD------
Mvan_3298|M.vanbaalenii_PYR-1 YLTGELPQFSGD-------
MAV_3088|M.avium_104 YLTGDLPDGLAP-------
Mb1711c|M.bovis_AF2122/97 YLTGELPDDLAP-------
Rv1685c|M.tuberculosis_H37Rv YLTGELPDDLAP-------
MMAR_2484|M.marinum_M YLTGELPEEIAS-------
MUL_1664|M.ulcerans_Agy99 YLNR---------------
MAB_2351c|M.abscessus_ATCC_199 YLTGALPSITP--------
MLBr_02568|M.leprae_Br4923 GLKGAPADRDFGPSIVAG-
*.