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MEGMNPEQPGLRERKKTRTRETVRREAFRLFELNGYAQTTVDQIAEAAFVSPRTFFRYFPTKESVLFSDD LFNPIIEEFLAAPAELSPVAAYRHAAARVFETMAGSDYDYIIARQRLLYDLPEAKGALWNEHVGAIRRLT SAIAKRLGRPEDDYQARVTAGAIIGVFMAASDDEPMSGEAFLEALDLLDQALPR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0350 | - | - | 100% (194) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3877 | - | 5e-50 | 51.61% (186) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_5173 | - | 9e-43 | 46.49% (185) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0710c | - | 3e-10 | 25.40% (189) | transcriptional regulatory protein |
| M. tuberculosis H37Rv | Rv0691c | - | 3e-10 | 25.40% (189) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_01070 | - | 2e-05 | 29.77% (131) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3837 | - | 7e-10 | 23.78% (164) | transcriptional regulatory protein TetR |
| M. marinum M | MMAR_2812 | - | 2e-11 | 39.81% (103) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4894 | - | 2e-46 | 49.73% (185) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5673 | - | 1e-17 | 39.13% (161) | transcriptional regulator |
| M. thermoresistible (build 8) | TH_3524 | - | 2e-14 | 35.44% (158) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_2933 | - | 2e-11 | 39.81% (103) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0384 | - | 6e-86 | 85.56% (187) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0710c|M.bovis_AF2122/97 ----------MPHESRVGRRRS-----TTPHHISDVAIELFAAHGFTDVS
Rv0691c|M.tuberculosis_H37Rv ----------MPHESRVGRRRS-----TTPHHISDVAIELFAAHGFTDVS
MAB_3837|M.abscessus_ATCC_1997 ---------MNAQPARVGRRPS-----TTRDEITAVAMTLFAQHGFDEVS
Mflv_0350|M.gilvum_PYR-GCK -----MEGMNPEQPGLRERKKT-----RTRETVRREAFRLFELNGYAQTT
Mvan_0384|M.vanbaalenii_PYR-1 -----MT--TGEQPSLRERKKT-----RTRETVRREAFRLFELNGYAQTT
MAV_4894|M.avium_104 -----MP-ASEAPPGLRERKKI-----KTRQAIRREAFRLIEQNGYAATT
MMAR_2812|M.marinum_M ---------MTVPTNRHELRRR-----STHEALRRAALKSFACKGFAQVT
MUL_2933|M.ulcerans_Agy99 ---------MTVPTNRHELRRR-----STHEALRRAALKSFARKGFAQVT
MSMEG_5673|M.smegmatis_MC2_155 ------MAYQTQQPGLRERKKQ-----RTRATLISAAIDLCVRQGYEQTT
TH_3524|M.thermoresistible__bu ------------------VRGH-----RNREALIAAAIDLFTVNGYEQTT
MLBr_01070|M.leprae_Br4923 MIVVGNFTQSNYVPASRGRRSSQLSGDDREQAILAVAERLLAERPLGDFS
: : * . :
Mb0710c|M.bovis_AF2122/97 VDDIARAAGIARRTLFRYYASKNAIPWGDFSTHLAQLQ-GLLDNIDSR-I
Rv0691c|M.tuberculosis_H37Rv VDDIARAAGIARRTLFRYYASKNAIPWGDFSTHLAQLQ-GLLDNIDSR-I
MAB_3837|M.abscessus_ATCC_1997 VDDIAAAAGIARRTVFRYYSSKNAIVWGDFDSHLGVMR-ALLDETADT-V
Mflv_0350|M.gilvum_PYR-GCK VDQIAEAAFVSPRTFFRYFPTKESVLFSDDLFNP-IIE-EFLAAPAEL-S
Mvan_0384|M.vanbaalenii_PYR-1 VDQIAEAADVSPRTFFRYFPTKESVLFSDDLLTP-IIE-AFLAAPAEL-S
MAV_4894|M.avium_104 VEQIAEAADVSPSTFFRYFGSKESLLLADDLDPL-ILD-ALKAQPREL-S
MMAR_2812|M.marinum_M VTELAREAGVTERTFFRHFPTKEAVLFQDYEN-------QLEWLAQAL-A
MUL_2933|M.ulcerans_Agy99 VTELAREAGVTERTFFRHFPTKEAVLFQDYEN-------QLEWLARAL-A
MSMEG_5673|M.smegmatis_MC2_155 VEQIAAAAEVSARTFSRYFATKDAVMLAFLDDVVDLVAGELAQQPPEL-G
TH_3524|M.thermoresistible__bu VEQIAEAAGVAPRTFFRHFAAKEDILFHGYADRLAEAT-RRFRAARSG-S
MLBr_01070|M.leprae_Br4923 VDELAKGAGISRPTFYFYFPSKNAVLLSLLDDLNMKSRSAVEALAEQLPA
* ::* * :: *. :: :*: :
Mb0710c|M.bovis_AF2122/97 QLRDALRAALLAFNTFDESE-TIRHRKRMRVILQTPELQAYSMTMYAGWR
Rv0691c|M.tuberculosis_H37Rv QLRDALRAALLAFNTFDESE-TIRHRKRMRVILQTPELQAYSMTMYAGWR
MAB_3837|M.abscessus_ATCC_1997 DTSTALRQAVLTFNDFPVDE-TPRHRMRMRMILEVPALQAYSMLMYTGWR
Mflv_0350|M.gilvum_PYR-GCK PVAAYRHAAARVFETMAGSD-YDYIIARQRLLYDLPEAKGALWNEHVGAI
Mvan_0384|M.vanbaalenii_PYR-1 PVAAYRHAAAQVFAAMAGPD-FDYVIARQRLLYALPEAKGALWNEHVKAI
MAV_4894|M.avium_104 LPQAFRRAYATVLSQLPDDQ-LEFESTRQRLMFSIPELKAAMYDEYYRTV
MMAR_2812|M.marinum_M QRPVSEPLFDAVLASVAAFP-HDLEVVRQAATARSELISADRIANHLRVV
MUL_2933|M.ulcerans_Agy99 QRPVSEPLFDAVLASVAAFP-HDLEVVRQAATARSELISADRIANHLRVV
MSMEG_5673|M.smegmatis_MC2_155 ELDAVFCAHITAFEKTRVAMPGQLTDDRLLAAARIFTSSPSLMQATMGFR
TH_3524|M.thermoresistible__bu LWKALAEASEAVATAIAENP--GIFLVRARMYGELPALRATMLRINDDWI
MLBr_01070|M.leprae_Br4923 DPAAVWRSAITAFFEVCGTH-RAVAVAGAAAKATSPEVRRLWSTVMQQWI
.
Mb0710c|M.bovis_AF2122/97 E-----VIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDE--S
Rv0691c|M.tuberculosis_H37Rv E-----VIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDE--S
MAB_3837|M.abscessus_ATCC_1997 D-----VIAQFVARRSGTDPGSLLPQTVAWTLLGVALAAYEQWLADE--S
Mflv_0350|M.gilvum_PYR-GCK R-----RLTSAIAKRLGRPEDDYQARVTAGAIIGVFMAASDD-------E
Mvan_0384|M.vanbaalenii_PYR-1 R-----VLTTAIAERLDRPEDD-QVRVTAGAIIGVFMAASDD-------A
MAV_4894|M.avium_104 T-----VAAEAIAHRIGRAADDFEVRVFAGALTGAMMAAFDS-------A
MMAR_2812|M.marinum_M QSSFAQVLTAFVRDRYADVANVDLVAEVAGATIAAALVVAVENWGRNGCA
MUL_2933|M.ulcerans_Agy99 QSSFAQVLTAFVRNRYADVANVDLVAEVAGATIAAALVVAVENWGRYGCA
MSMEG_5673|M.smegmatis_MC2_155 P----APLFEVLAKRMGVSADDRKIALIASLWNAIMTTALVQLVPDVDWA
TH_3524|M.thermoresistible__bu D-----QMTTEVARWLGSDAAVDVRPRLAATVINGANRTAIDLWVSADGK
MLBr_01070|M.leprae_Br4923 DYN---TAAIQAERKCGVAPDTIPAEDLAVALQLMTERVMAATFSDEKPL
* .
Mb0710c|M.bovis_AF2122/97 VSLTEALGAAFDVVGAGLDRLNQ---------------
Rv0691c|M.tuberculosis_H37Rv VSLTEALGAAFDVVGAGLDRLNQ---------------
MAB_3837|M.abscessus_ATCC_1997 SKLTTLLGKGFDAAEVGLRALR----------------
Mflv_0350|M.gilvum_PYR-GCK PMSGEAFLEALDLLDQALPR------------------
Mvan_0384|M.vanbaalenii_PYR-1 PLDGEAFLQALDILETGLPE------------------
MAV_4894|M.avium_104 PTTPETIYRALDFMDAGMPLD-----------------
MMAR_2812|M.marinum_M VDLGELVAASLDLVRSGLAPLS----------------
MUL_2933|M.ulcerans_Agy99 EDLGELVAASLDLVRSGLAPLS----------------
MSMEG_5673|M.smegmatis_MC2_155 TVTVERIVNQMRTTYAEFLEVAGRRHEFA---------
TH_3524|M.thermoresistible__bu GDLVELMADAVRLVRPTLDRIERESRTVANPVRRRDVV
MLBr_01070|M.leprae_Br4923 IPDKKVIDTLVHIWLASIYGS-----------------
. . :