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M. gilvum PYR-GCK Mflv_4953 (-)

annotation: TetR family transcriptional regulator
coordinates: 5273524 - 5274078
length: 184

VSTLVDAAAQVFSREGLTATTNRIADRAGLSIGTLYQYFPDKLALLRAVAERHVRDADRELTAVFAALRT
EAPPFDATMRAVLGAVVAVHAGGGRLHALLHRMVPADARDLETVQALEDRICDEVAFHLKRCDRGGDDVE
MTARTLVHAVDAQLHRVLSRDGFDVGDATDTLMVTVDRLAPPHG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_4953--100% (184)TetR family transcriptional regulator
M. gilvum PYR-GCKMflv_4581-9e-0833.09% (136) TetR family transcriptional regulator
M. gilvum PYR-GCKMflv_0142-1e-0748.08% (52) TetR family transcriptional regulator

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0068c-7e-0835.42% (96) TetR family transcriptional regulator
M. tuberculosis H37RvRv0067c-7e-0835.42% (96) TetR family transcriptional regulator
M. leprae Br4923MLBr_00815-3e-0644.12% (68) putative TetR-family transcriptional regulator
M. abscessus ATCC 19977MAB_3372-6e-1432.08% (159) TetR family transcriptional regulator
M. marinum MMMAR_0684-1e-0737.78% (90) putative regulatory protein
M. avium 104MAV_4593-2e-0729.14% (151) TetR family protein transcriptional regulator
M. smegmatis MC2 155MSMEG_6532-2e-4653.80% (184) transcriptional regulatory protein
M. thermoresistible (build 8)TH_0452-2e-0645.59% (68) PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY
M. ulcerans Agy99MUL_1163-1e-0527.59% (174) TetR family transcriptional regulator
M. vanbaalenii PYR-1Mvan_0955-1e-0731.61% (155) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mb0068c|M.bovis_AF2122/97           --------------------MAPTDRRVRADAARNR-----ARVLEVAYQ
Rv0067c|M.tuberculosis_H37Rv        --------------------MAPTDRRVRADAARNR-----ARVLEVAYQ
Mflv_4953|M.gilvum_PYR-GCK          ----------------------------------------MSTLVDAAAQ
MSMEG_6532|M.smegmatis_MC2_155      -------------------MVVAMSDAPRKKPRQRRSRETVEVVLEAAAQ
MAB_3372|M.abscessus_ATCC_1997      --------MAILAFGEGFDIMSSSRLQPRKQPRQDRAEATRRRILEAAAH
MMAR_0684|M.marinum_M               --------------------MPRKSATFRKVPTQDRSKDTVKRILDAARM
Mvan_0955|M.vanbaalenii_PYR-1       -------------------MTSDVASRLRRAPRQERSRAMVDRILDAGEQ
MLBr_00815|M.leprae_Br4923          MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
TH_0452|M.thermoresistible__bu      MSEVADTTARQEITPTNGGTTSGAAAGANRRGNRLPRDERRNQLLIAASE
MAV_4593|M.avium_104                -------------------------MVGRSDARRNR-----QRLLEAATA
MUL_1163|M.ulcerans_Agy99           -----------------------MAGGTKRLPRAIRE----QQMLDAAVQ
                                                                               :: ..  

Mb0068c|M.bovis_AF2122/97           TFAADGLSV-PVDEIARRAGVGAGTVYRHFPTKEALFQAVIADRMHRIID
Rv0067c|M.tuberculosis_H37Rv        TFAADGLSV-PVDEIARRAGVGAGTVYRHFPTKEALFQAVIADRMHRIID
Mflv_4953|M.gilvum_PYR-GCK          VFSREGLTA-TTNRIADRAGLSIGTLYQYFPDKLALLRAVAERHVRDADR
MSMEG_6532|M.smegmatis_MC2_155      VFDREGLAA-TTNRIAERAGVSIGSLYQYFPNKHALLNALAQRHVQTASA
MAB_3372|M.abscessus_ATCC_1997      VFADFGYAAGTTNRIAERAEISIGSLYQYFPNKDAILVELMTAHTHRGFA
MMAR_0684|M.marinum_M               LLEERGYDGTSTNRIAAAAGISPGSLYQYFANKDAILHAVVAEYTQQLLD
Mvan_0955|M.vanbaalenii_PYR-1       MLIAHGFDGASTNRIAAAAGISPGSLYQYFPNKDAIAAAVIDRFSDQLSA
MLBr_00815|M.leprae_Br4923          VFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLVS
TH_0452|M.thermoresistible__bu      VFVDRGYHAAGMDEIAERAGVSKPVLYQHFSSKLELYLAVLQRHVDNLVS
MAV_4593|M.avium_104                AFTAHGASV-SLESIARDAGVGIGTLYRHFPNREALVEAVYRAELAEVAA
MUL_1163|M.ulcerans_Agy99           MFSANGYHETSMDTIAAAAQISKPMLYLYYGSKEDLFGACLNREMSRFID
                                     :   *      : **  * :.   :* ::  :  :              

Mb0068c|M.bovis_AF2122/97           KGHALLKSKHPGD----ALFAFLRSMVLQWGATDRGLVEALAGVGIEISS
Rv0067c|M.tuberculosis_H37Rv        KGHALLKSKHPGD----ALFAFLRSMVLQWGATDRGLVEALAGVGIEISS
Mflv_4953|M.gilvum_PYR-GCK          ELTAVFAALRTEAPPFDATMRAVLGAVVAVHAGGGRLHALLHRMVPADAR
MSMEG_6532|M.smegmatis_MC2_155      RLDAVFAELRHETPEFDQTLRSILAVVVDLHHDRPALHRLMHRVAVPRDD
MAB_3372|M.abscessus_ATCC_1997      LIHQHLAAGLPDT--IEDTVRVFVGSAIANHRDSPRLHRVLFEEAPRPPE
MMAR_0684|M.marinum_M               QVTGNLASLVRSE--HDVPLSAAIEAQVDAMLERPQILRVISGQLPGRTS
Mvan_0955|M.vanbaalenii_PYR-1       RVAARVSERLDQP--APDYVRESIAALIEALDVHPEFLRAVMEQTPRLGT
MLBr_00815|M.leprae_Br4923          SVQQALRTTTNNR----QRLHAAVQAFFDFIEHDGQGYRLIFENDNITEP
TH_0452|M.thermoresistible__bu      GVRQALRTTTDNR----QRLRAAVQAFFDFIEHDGQGYRLIFENDYVTEP
MAV_4593|M.avium_104                AAAQLLQRHPPKA-----ALRRWMDRYATFVATKRGMAESLQ--AIFESG
MUL_1163|M.ulcerans_Agy99           AVRADIDLSQSPK----DLLRNAIVSFLRYIDQNQASWIVMYTQAVSSQA
                                         .             .                    :         

Mb0068c|M.bovis_AF2122/97           --AAPEA-EADFLDLLTDLLRAAQRAGTVRPDVDVLEVKTLLVGCQAMQS
Rv0067c|M.tuberculosis_H37Rv        --AAPEA-EADFLDLLTDLLRAAQRAGTVRPDVDVLEVKTLLVGCQAMQS
Mflv_4953|M.gilvum_PYR-GCK          DLETVQA-LEDRICDEVAFHLKRCD--RGGDDVEMTARTLVHAVDAQLHR
MSMEG_6532|M.smegmatis_MC2_155      QLAALQE-FENRLAGEVAFHLVRCGRVRDPDDASATARTVVHAVDAHLHR
MAB_3372|M.abscessus_ATCC_1997      FLAMLHR-SEDAVIAAAEAVLAAHP-EVRVTETDTAARMVVATIESLVHR
MMAR_0684|M.marinum_M               ADVLRPL-RELMTATIKGYAIAAPDQS-IDMDVDAATWIIVQLLG-STIR
Mvan_0955|M.vanbaalenii_PYR-1       GSKLVAF-EQRIGELTVAYLTINKRQVRTDVTVDVAAWMLVRMVEHLCVR
MLBr_00815|M.leprae_Br4923          RVAAQVR-VATESCIDAVFALISADSRLDPHRARMVAVGLVGISVDCARY
TH_0452|M.thermoresistible__bu      QVAAQVK-VATEACTDAVFDLISQDSGLEAHRARMIAVGLVAISVDCARY
MAV_4593|M.avium_104                ALVPSQT-RDSIVGAVETLLRAGADDASLRADVQADD-----VVSSLIGI
MUL_1163|M.ulcerans_Agy99           FAQTVREGREQIVELVAGMLRAGTRSPRSDAEIDMMAAALVGAGEAVANR
                                                                                      

Mb0068c|M.bovis_AF2122/97           YNAELAAKVTDVALDGLRANRK-------------------
Rv0067c|M.tuberculosis_H37Rv        YNAELAAKVTDVALDGLRANRK-------------------
Mflv_4953|M.gilvum_PYR-GCK          VLS-RDGFDVGDATDTLMVTVDRLAPPHG------------
MSMEG_6532|M.smegmatis_MC2_155      VLP-HREVTREAAVDDLVDLVERLLRP--------------
MAB_3372|M.abscessus_ATCC_1997      LIAGPRPIDPQLFEDQLVDMLTRYLTG--------------
MMAR_0684|M.marinum_M               YVVDEPPIAKDVFVTEMTRFVMSSPVAWRCSARPAAVPTA-
Mvan_0955|M.vanbaalenii_PYR-1       YILDQPSIEREKFIDEVTLMALNYLRPWPTPPEDCFGSPR-
MLBr_00815|M.leprae_Br4923          WLDTNRPISKSDAVEGTVQFAWGGLSHVPLTRL--------
TH_0452|M.thermoresistible__bu      WLHADRPISKEDAVEGTVQFAWGGLSHVPLTRS--------
MAV_4593|M.avium_104                FLVSGSPEQTGRMLDLLVAGVTR------------------
MUL_1163|M.ulcerans_Agy99           LSAGDTDVD--EAAEMMIDLLWRGLKGAPSDREIGSNFAAG