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MVVAMSDAPRKKPRQRRSRETVEVVLEAAAQVFDREGLAATTNRIAERAGVSIGSLYQYFPNKHALLNAL AQRHVQTASARLDAVFAELRHETPEFDQTLRSILAVVVDLHHDRPALHRLMHRVAVPRDDQLAALQEFEN RLAGEVAFHLVRCGRVRDPDDASATARTVVHAVDAHLHRVLPHREVTREAAVDDLVDLVERLLRP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6532 | - | - | 100% (205) | transcriptional regulatory protein |
| M. smegmatis MC2 155 | MSMEG_3354 | - | 3e-08 | 36.36% (77) | TetR family protein transcriptional regulatory protein |
| M. smegmatis MC2 155 | MSMEG_6479 | - | 1e-07 | 27.15% (151) | putative transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0068c | - | 1e-07 | 36.67% (90) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4953 | - | 2e-46 | 53.80% (184) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0067c | - | 1e-07 | 36.67% (90) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 7e-06 | 26.84% (190) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3372 | - | 1e-24 | 38.58% (197) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0684 | - | 4e-14 | 27.23% (191) | putative regulatory protein |
| M. avium 104 | MAV_1611 | - | 3e-07 | 32.47% (154) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0452 | - | 6e-08 | 27.32% (194) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. ulcerans Agy99 | MUL_4876 | - | 7e-07 | 31.40% (121) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0955 | - | 2e-18 | 35.82% (201) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0068c|M.bovis_AF2122/97 --------------------MAPTDRRVRADAARNR-----ARVLEVAYQ
Rv0067c|M.tuberculosis_H37Rv --------------------MAPTDRRVRADAARNR-----ARVLEVAYQ
MSMEG_6532|M.smegmatis_MC2_155 -------------------MVVAMSDAPRKKPRQRRSRETVEVVLEAAAQ
Mflv_4953|M.gilvum_PYR-GCK ----------------------------------------MSTLVDAAAQ
MAB_3372|M.abscessus_ATCC_1997 --------MAILAFGEGFDIMSSSRLQPRKQPRQDRAEATRRRILEAAAH
MMAR_0684|M.marinum_M --------------------MPRKSATFRKVPTQDRSKDTVKRILDAARM
Mvan_0955|M.vanbaalenii_PYR-1 -------------------MTSDVASRLRRAPRQERSRAMVDRILDAGEQ
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
TH_0452|M.thermoresistible__bu MSEVADTTARQEITPTNGGTTSGAAAGANRRGNRLPRDERRNQLLIAASE
MUL_4876|M.ulcerans_Agy99 -----------------MTVPTFSTRSQLGRPVGARGEQTRQRIITAAMR
MAV_1611|M.avium_104 --------------------MLLGMSPVKPLRSRPTRGEVRDRILDAAAK
:: ..
Mb0068c|M.bovis_AF2122/97 TFAADGLSV-PVDEIARRAGVGAGTVYRHFPTKEALFQAVIADRMHRIID
Rv0067c|M.tuberculosis_H37Rv TFAADGLSV-PVDEIARRAGVGAGTVYRHFPTKEALFQAVIADRMHRIID
MSMEG_6532|M.smegmatis_MC2_155 VFDREGLAA-TTNRIAERAGVSIGSLYQYFPNKHALLNALAQRHVQTASA
Mflv_4953|M.gilvum_PYR-GCK VFSREGLTA-TTNRIADRAGLSIGTLYQYFPDKLALLRAVAERHVRDADR
MAB_3372|M.abscessus_ATCC_1997 VFADFGYAAGTTNRIAERAEISIGSLYQYFPNKDAILVELMTAHTHRGFA
MMAR_0684|M.marinum_M LLEERGYDGTSTNRIAAAAGISPGSLYQYFANKDAILHAVVAEYTQQLLD
Mvan_0955|M.vanbaalenii_PYR-1 MLIAHGFDGASTNRIAAAAGISPGSLYQYFPNKDAIAAAVIDRFSDQLSA
MLBr_00815|M.leprae_Br4923 VFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLVS
TH_0452|M.thermoresistible__bu VFVDRGYHAAGMDEIAERAGVSKPVLYQHFSSKLELYLAVLQRHVDNLVS
MUL_4876|M.ulcerans_Agy99 CVAEAGPAQASIREIAKAADMTSGSLYHYFPNKSELLNATATEIEEIVLP
MAV_1611|M.avium_104 VFAAEGFAGATIDAIGQAAGFTKGAVYSNFESKDELFLALLDREFELRGQ
. * *. * . :* * * :
Mb0068c|M.bovis_AF2122/97 KGHALLKSKHPGD----ALFAFLRSMVLQWGATDRGLVEALAG--VGIEI
Rv0067c|M.tuberculosis_H37Rv KGHALLKSKHPGD----ALFAFLRSMVLQWGATDRGLVEALAG--VGIEI
MSMEG_6532|M.smegmatis_MC2_155 RLDAVFAELRHETPEFDQTLRSILAVVVDLHHDRPALHRLMHR--VAVPR
Mflv_4953|M.gilvum_PYR-GCK ELTAVFAALRTEAPPFDATMRAVLGAVVAVHAGGGRLHALLHR--MVPAD
MAB_3372|M.abscessus_ATCC_1997 LIHQHLAAGLPDT--IEDTVRVFVGSAIANHRDSPRLHRVLFE--EAPRP
MMAR_0684|M.marinum_M QVTGNLASLVRSE--HDVPLSAAIEAQVDAMLERPQILRVISG--QLPGR
Mvan_0955|M.vanbaalenii_PYR-1 RVAARVSERLDQP--APDYVRESIAALIEALDVHPEFLRAVME--QTPRL
MLBr_00815|M.leprae_Br4923 SVQQALRTTTNNR----QRLHAAVQAFFDFIEHDGQGYRLIFE--NDNIT
TH_0452|M.thermoresistible__bu GVRQALRTTTDNR----QRLRAAVQAFFDFIEHDGQGYRLIFE--NDYVT
MUL_4876|M.ulcerans_Agy99 RLHAAAASSDDIVDRLDAVLDESKRLMRDYPYLAGFLRAVRAE--NADQT
MAV_1611|M.avium_104 QIAIALDRSAGDT---TAAAREVSRSVLDSVRDHSDYYVLLVEYWLRAQR
Mb0068c|M.bovis_AF2122/97 SS--AAPEAEADFLDLLTDLLRAAQRAGTVRPDVD-VLEVKTLLVGCQAM
Rv0067c|M.tuberculosis_H37Rv SS--AAPEAEADFLDLLTDLLRAAQRAGTVRPDVD-VLEVKTLLVGCQAM
MSMEG_6532|M.smegmatis_MC2_155 DDQLAALQEFENRLAGEVAFHLVRCGRVRDPDDAS-ATARTVVHAVDAHL
Mflv_4953|M.gilvum_PYR-GCK ARDLETVQALEDRICDEVAFHLKRCD--RGGDDVE-MTARTLVHAVDAQL
MAB_3372|M.abscessus_ATCC_1997 PEFLAMLHRSEDAVIAAAEAVLAAHP-EVRVTETD-TAARMVVATIESLV
MMAR_0684|M.marinum_M TSADVLRPLRELMTATIKGYAIAAPDQS-IDMDVD-AATWIIVQLLG-ST
Mvan_0955|M.vanbaalenii_PYR-1 GTGSKLVAFEQRIGELTVAYLTINKRQVRTDVTVD-VAAWMLVRMVEHLC
MLBr_00815|M.leprae_Br4923 EPRVAAQVRVATESCIDAVFALISADSRLDPHRAR-MVAVGLVGISVDCA
TH_0452|M.thermoresistible__bu EPQVAAQVKVATEACTDAVFDLISQDSGLEAHRAR-MIAVGLVAISVDCA
MUL_4876|M.ulcerans_Agy99 GGGRRTYPGSKALRDVITEIVDDARGRGVLSAGIAPGAAVDAICALTRGL
MAV_1611|M.avium_104 DPQLRERLIERRRAAADQALHIVESTDTVPGDRRLTDIAQLVVTLNLGVA
:
Mb0068c|M.bovis_AF2122/97 QSYNAELAAKVTDVALDGLRANRK------------------
Rv0067c|M.tuberculosis_H37Rv QSYNAELAAKVTDVALDGLRANRK------------------
MSMEG_6532|M.smegmatis_MC2_155 HRVLP-HREVTREAAVDDLVDLVERLLRP-------------
Mflv_4953|M.gilvum_PYR-GCK HRVLS-RDGFDVGDATDTLMVTVDRLAPPHG-----------
MAB_3372|M.abscessus_ATCC_1997 HRLIAGPRPIDPQLFEDQLVDMLTRYLTG-------------
MMAR_0684|M.marinum_M IRYVVDEPPIAKDVFVTEMTRFVMSSPVAWRCSARPAAVPTA
Mvan_0955|M.vanbaalenii_PYR-1 VRYILDQPSIEREKFIDEVTLMALNYLRPWPTPPEDCFGSPR
MLBr_00815|M.leprae_Br4923 RYWLDTNRPISKSDAVEGTVQFAWGGLSHVPLTRL-------
TH_0452|M.thermoresistible__bu RYWLHADRPISKEDAVEGTVQFAWGGLSHVPLTRS-------
MUL_4876|M.ulcerans_Agy99 TEQAANLGPQSYDVTLDSAKQLLRGSLFAGAKPTATRRT---
MAV_1611|M.avium_104 MEEVLRPGTINPDLLAQLITALLESIPV--------------