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LAILAFGEGFDIMSSSRLQPRKQPRQDRAEATRRRILEAAAHVFADFGYAAGTTNRIAERAEISIGSLYQ YFPNKDAILVELMTAHTHRGFALIHQHLAAGLPDTIEDTVRVFVGSAIANHRDSPRLHRVLFEEAPRPPE FLAMLHRSEDAVIAAAEAVLAAHPEVRVTETDTAARMVVATIESLVHRLIAGPRPIDPQLFEDQLVDMLT RYLTG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3372 | - | - | 100% (215) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3437c | - | 4e-10 | 24.35% (193) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1525c | - | 5e-08 | 35.48% (124) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0310 | - | 4e-07 | 27.48% (131) | TetR/ACRR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4953 | - | 8e-14 | 32.08% (159) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1255c | - | 3e-09 | 31.06% (161) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_00717 | - | 1e-06 | 33.33% (96) | putative TetR-family transcriptional regulator |
| M. marinum M | MMAR_0684 | - | 2e-15 | 28.35% (194) | putative regulatory protein |
| M. avium 104 | MAV_2588 | - | 6e-09 | 29.21% (178) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6532 | - | 2e-24 | 38.58% (197) | transcriptional regulatory protein |
| M. thermoresistible (build 8) | TH_2984 | - | 4e-10 | 25.71% (210) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_4876 | - | 3e-09 | 36.19% (105) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0955 | - | 8e-18 | 33.00% (203) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4953|M.gilvum_PYR-GCK --------------------------------MSTLVDAAAQVFSREGLT
MSMEG_6532|M.smegmatis_MC2_155 -----------MVVAMSDAPRKKPRQRRSRETVEVVLEAAAQVFDREGLA
MAB_3372|M.abscessus_ATCC_1997 MAILAFGEGFDIMSSSRLQPRKQPRQDRAEATRRRILEAAAHVFADFGYA
MMAR_0684|M.marinum_M ------------MPRKSATFRKVPTQDRSKDTVKRILDAARMLLEERGYD
Mvan_0955|M.vanbaalenii_PYR-1 -----------MTSDVASRLRRAPRQERSRAMVDRILDAGEQMLIAHGFD
MAV_2588|M.avium_104 ----MARTPDKLRRSGYAPAANHGVGRRGLHTRERILGSAAEVFLANGFH
Rv1255c|M.tuberculosis_H37Rv -----------------MAGTDWLSARRTELAADRILDAAERLFTQRDPA
MUL_4876|M.ulcerans_Agy99 ---------MTVPTFSTRSQLGRPVGARGEQTRQRIITAAMRCVAEAGPA
TH_2984|M.thermoresistible__bu ------------MPTTRQNRRSSDSGSVDTGARSRLIEATAQIMREEGYA
Mb0310|M.bovis_AF2122/97 -----------------MGVPAKKKQQQGERSRESILDATERLMATKGYA
MLBr_00717|M.leprae_Br4923 -------------------MTTARRRLSPEDRRAELLALGAEVFGKRPYD
:: .
Mflv_4953|M.gilvum_PYR-GCK A-TTNRIADRAGLSIGTLYQYFPDKLALLRAVAERHVRDADRE-------
MSMEG_6532|M.smegmatis_MC2_155 A-TTNRIAERAGVSIGSLYQYFPNKHALLNALAQRHVQTASAR-------
MAB_3372|M.abscessus_ATCC_1997 AGTTNRIAERAEISIGSLYQYFPNKDAILVELMTAHTHRGFAL-------
MMAR_0684|M.marinum_M GTSTNRIAAAAGISPGSLYQYFANKDAILHAVVAEYTQQLLDQ-------
Mvan_0955|M.vanbaalenii_PYR-1 GASTNRIAAAAGISPGSLYQYFPNKDAIAAAVIDRFSDQLSAR-------
MAV_2588|M.avium_104 ATSLDAIAKTAGASRATVYQYFAGKEEIFRELSALAERDVLAHGEHLGEL
Rv1255c|M.tuberculosis_H37Rv SIGMNEIAKAAGCSRATLYRYFDSREALRTAYVHRETRR-----------
MUL_4876|M.ulcerans_Agy99 QASIREIAKAADMTSGSLYHYFPNKSELLNATATEIEEIVLPR-------
TH_2984|M.thermoresistible__bu AATSRRVAARAGVKQALVYYYFPTMDDLFVEVLRTGAEAALER-------
Mb0310|M.bovis_AF2122/97 ATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFFAA-------
MLBr_00717|M.leprae_Br4923 EVRIDEIAERAGVSRALMYHYFPDKRAFFAAVVKDEADRLYAA-------
: . . :* :* .
Mflv_4953|M.gilvum_PYR-GCK ----------------LTAVFAALRTEAPPFDATMRAVLGAVVAVHAGGG
MSMEG_6532|M.smegmatis_MC2_155 ----------------LDAVFAELRHETPEFDQTLRSILAVVVDLHHDRP
MAB_3372|M.abscessus_ATCC_1997 ----------------IHQHLAAGLPDT--IEDTVRVFVGSAIANHRDSP
MMAR_0684|M.marinum_M ----------------VTGNLASLVRSE--HDVPLSAAIEAQVDAMLERP
Mvan_0955|M.vanbaalenii_PYR-1 ----------------VAARVSERLDQP--APDYVRESIAALIEALDVHP
MAV_2588|M.avium_104 GPTVDGVDALHRWLVAWADIYDAHAAVFAEFPGIGTATGLAVIDASSAAA
Rv1255c|M.tuberculosis_H37Rv ----------------LGREIMVKIADVVEPAERLLVSITTTLRMVRDNP
MUL_4876|M.ulcerans_Agy99 --------------------LHAAAASSDDIVDRLDAVLDESKRLMRDYP
TH_2984|M.thermoresistible__bu ----------------------MRTALTDDDPLRALWELNSDTRLTSLNS
Mb0310|M.bovis_AF2122/97 --------------------IPTWDEAHGPVEQRSERQLTELVSLQSQHP
MLBr_00717|M.leprae_Br4923 --------------------TNIPPPAGLTMFEEVRVGVLAYMAYHKQNP
Mflv_4953|M.gilvum_PYR-GCK RLHALLHRMVPAD-------------------------------------
MSMEG_6532|M.smegmatis_MC2_155 ALHRLMHRVAVPR-------------------------------------
MAB_3372|M.abscessus_ATCC_1997 RLHRVLFEEAPRP-------------------------------------
MMAR_0684|M.marinum_M QILRVISGQLPGR-------------------------------------
Mvan_0955|M.vanbaalenii_PYR-1 EFLRAVMEQTPRL-------------------------------------
MAV_2588|M.avium_104 QFHQTVTDRLRRTRLRDLEADDAAAALGRIPHMVHLYRYRDMLPLPARAT
Rv1255c|M.tuberculosis_H37Rv ALAAWFTTTRPPIG------------------------------------
MUL_4876|M.ulcerans_Agy99 YLAGFLRAVRAEN-------------------------------------
TH_2984|M.thermoresistible__bu EFIALANHRKAIR-------------------------------------
Mb0310|M.bovis_AF2122/97 DFLRLFYLLSMER-------------------------------------
MLBr_00717|M.leprae_Br4923 EAAWAAYVGLGRSD------------------------------------
Mflv_4953|M.gilvum_PYR-GCK ------------------ARDLETVQALED--------------------
MSMEG_6532|M.smegmatis_MC2_155 ------------------DDQLAALQEFEN--------------------
MAB_3372|M.abscessus_ATCC_1997 ------------------PEFLAMLHRSED--------------------
MMAR_0684|M.marinum_M ------------------TSADVLRPLREL--------------------
Mvan_0955|M.vanbaalenii_PYR-1 ------------------GTGSKLVAFEQR--------------------
MAV_2588|M.avium_104 VTWSLTGALQLMLFPETPADVLQVVAPARDGCARTTPRALDYAAATPAAV
Rv1255c|M.tuberculosis_H37Rv ---------------------GEMAGRSE---------------------
MUL_4876|M.ulcerans_Agy99 ------------------ADQTGGGRRTYPG-------------------
TH_2984|M.thermoresistible__bu ---------------------AELKAYAER--------------------
Mb0310|M.bovis_AF2122/97 ------------------SQDPVVAAVVRR--------------------
MLBr_00717|M.leprae_Br4923 ------------------PVLLGIDDEAKNR-------------------
Mflv_4953|M.gilvum_PYR-GCK ----------------RICDEVAFHLKRCD--RGGDDVEMTARTLVH---
MSMEG_6532|M.smegmatis_MC2_155 ----------------RLAGEVAFHLVRCGRVRDPDDASATARTVVH---
MAB_3372|M.abscessus_ATCC_1997 ----------------AVIAAAEAVLAAHP-EVRVTETDTAARMVVA---
MMAR_0684|M.marinum_M ----------------MTATIKGYAIAAPDQS-IDMDVDAATWIIVQ---
Mvan_0955|M.vanbaalenii_PYR-1 ----------------IGELTVAYLTINKRQVRTDVTVDVAAWMLVR---
MAV_2588|M.avium_104 EASGSPIPQDVLSVSSALFAERGYYAIGMEEIAAAADVSRATLYRYF---
Rv1255c|M.tuberculosis_H37Rv -----------------VIAALAAAFLNSLGPDDPTTVERRARWVVR---
MUL_4876|M.ulcerans_Agy99 ---------------SKALRDVITEIVDDARGRGVLSAGIAPGAAVD---
TH_2984|M.thermoresistible__bu ------------------VRDIETAAVTVALRARGVDLDDHPPVAVS---
Mb0310|M.bovis_AF2122/97 ----------------VRNTAIARFRDSITHLLPSDIPPGKADLVVA---
MLBr_00717|M.leprae_Br4923 -------------QMEHIMSRIGDVVSVVPESKLHPDIERDLRVIVHGWL
Mflv_4953|M.gilvum_PYR-GCK AVDAQLHRVLS-RDGFDVGDATDTLMVTVDRLAPPHG-------------
MSMEG_6532|M.smegmatis_MC2_155 AVDAHLHRVLP-HREVTREAAVDDLVDLVERLLRP---------------
MAB_3372|M.abscessus_ATCC_1997 TIESLVHRLIAGPRPIDPQLFEDQLVDMLTRYLTG---------------
MMAR_0684|M.marinum_M LLG-STIRYVVDEPPIAKDVFVTEMTRFVMSSPVAWRCSARPAAVPTA--
Mvan_0955|M.vanbaalenii_PYR-1 MVEHLCVRYILDQPSIEREKFIDEVTLMALNYLRPWPTPPEDCFGSPR--
MAV_2588|M.avium_104 STKDKILAELTRRAVAEIEKHAAALPAKAADSLTEWMLGYVRFHRTYRGV
Rv1255c|M.tuberculosis_H37Rv MLT--SLLMFPGRDEADERAMIAEFVVPIVTPASAAARKAGHPGPE----
MUL_4876|M.ulcerans_Agy99 AICALTRGLTEQAANLGPQSYDVTLDSAKQLLRGSLFAGAKPTATRRT--
TH_2984|M.thermoresistible__bu MLIAQIARSLCNERAVGVTLGHDELRAFMDRLMTQLGAPARASAPPPAQR
Mb0310|M.bovis_AF2122/97 ELTAFAVALSDGVYFAGHLEPDTTDVERMYRRLRQALEALIPVLLEET--
MLBr_00717|M.leprae_Br4923 AFTFEVCRQRIMDPSTDADRLADSCAHALLDAIARVPEISKELADAMAIA
Mflv_4953|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6532|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3372|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_0684|M.marinum_M --------------------------------------------------
Mvan_0955|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_2588|M.avium_104 IRAWFDGAVAEQLSNADVDHGIGAIFQAVAALLSTVDLPPGIDADVAGAV
Rv1255c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_4876|M.ulcerans_Agy99 --------------------------------------------------
TH_2984|M.thermoresistible__bu --------------------------------------------------
Mb0310|M.bovis_AF2122/97 --------------------------------------------------
MLBr_00717|M.leprae_Br4923 RQPPQ---------------------------------------------
Mflv_4953|M.gilvum_PYR-GCK ---------------------------------------
MSMEG_6532|M.smegmatis_MC2_155 ---------------------------------------
MAB_3372|M.abscessus_ATCC_1997 ---------------------------------------
MMAR_0684|M.marinum_M ---------------------------------------
Mvan_0955|M.vanbaalenii_PYR-1 ---------------------------------------
MAV_2588|M.avium_104 FVAVLGRMSEPTGASGPNSDEQAAELMVKLLRRSLLREA
Rv1255c|M.tuberculosis_H37Rv ---------------------------------------
MUL_4876|M.ulcerans_Agy99 ---------------------------------------
TH_2984|M.thermoresistible__bu ---------------------------------------
Mb0310|M.bovis_AF2122/97 ---------------------------------------
MLBr_00717|M.leprae_Br4923 ---------------------------------------