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MTSDVASRLRRAPRQERSRAMVDRILDAGEQMLIAHGFDGASTNRIAAAAGISPGSLYQYFPNKDAIAAA VIDRFSDQLSARVAARVSERLDQPAPDYVRESIAALIEALDVHPEFLRAVMEQTPRLGTGSKLVAFEQRI GELTVAYLTINKRQVRTDVTVDVAAWMLVRMVEHLCVRYILDQPSIEREKFIDEVTLMALNYLRPWPTPP EDCFGSPR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0955 | - | - | 100% (218) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_2968 | - | 5e-15 | 28.65% (185) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_3432 | - | 7e-09 | 30.09% (113) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1561 | - | 2e-09 | 23.92% (209) | transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3251 | - | 4e-14 | 29.05% (179) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1534 | - | 2e-09 | 23.92% (209) | transcriptional regulator |
| M. leprae Br4923 | MLBr_02568 | - | 2e-09 | 26.86% (175) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3372 | - | 6e-18 | 33.00% (203) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0684 | - | 3e-30 | 35.32% (201) | putative regulatory protein |
| M. avium 104 | MAV_4678 | - | 2e-10 | 30.05% (193) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6532 | - | 2e-18 | 35.82% (201) | transcriptional regulatory protein |
| M. thermoresistible (build 8) | TH_1623 | - | 1e-08 | 36.11% (72) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_1163 | - | 1e-09 | 28.92% (166) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0955|M.vanbaalenii_PYR-1 -----------MTSDVASRLRRAPRQERSRAMVDRILDAGEQMLIAHGFD
MMAR_0684|M.marinum_M ------------MPRKSATFRKVPTQDRSKDTVKRILDAARMLLEERGYD
MAB_3372|M.abscessus_ATCC_1997 MAILAFGEGFDIMSSSRLQPRKQPRQDRAEATRRRILEAAAHVFADFGYA
MSMEG_6532|M.smegmatis_MC2_155 -----------MVVAMSDAPRKKPRQRRSRETVEVVLEAAAQVFDREGLA
Mb1561|M.bovis_AF2122/97 ------------MSRASARRRRAVSDEDKSQRRDEILAAAKIVFAHKGFH
Rv1534|M.tuberculosis_H37Rv ------------MSRASARRRRAVSDEDKSQRRDEILAAAKIVFAHKGFH
MLBr_02568|M.leprae_Br4923 ------------MAGGAKRIPRAVREQ-------QMLDAAVQMFSVNGYH
MUL_1163|M.ulcerans_Agy99 ------------MAGGTKRLPRAIREQ-------QMLDAAVQMFSANGYH
Mflv_3251|M.gilvum_PYR-GCK ----------MSAETRSSGRRKLPKQERSREMVAKIVQTTAALLIKTEPE
MAV_4678|M.avium_104 -------------MDGRKRRWHQHKVDRRNELVDGTIDAIRRLG-----G
TH_1623|M.thermoresistible__bu --------VRSRSNEETMASSTRRVGAETSKTRDTLLNCVEQMMLAEGYA
: :
Mvan_0955|M.vanbaalenii_PYR-1 GASTNRIAAAAGISPGSLYQYFPNKDAIAAAVIDRFSD-QLSARVAARVS
MMAR_0684|M.marinum_M GTSTNRIAAAAGISPGSLYQYFANKDAILHAVVAEYTQ-QLLDQVTGNLA
MAB_3372|M.abscessus_ATCC_1997 AGTTNRIAERAEISIGSLYQYFPNKDAILVELMTAHTH-RGFALIHQHLA
MSMEG_6532|M.smegmatis_MC2_155 A-TTNRIAERAGVSIGSLYQYFPNKHALLNALAQRHVQ-TASARLDAVFA
Mb1561|M.bovis_AF2122/97 ATTVADIAKQAGLAYGLIYWYFDSKDDLFHALMAGEEE-ALRAHVAAELA
Rv1534|M.tuberculosis_H37Rv ATTVADIAKQAGLAYGLIYWYFDSKDDLFHALMAGEEE-ALRAHVAAELA
MLBr_02568|M.leprae_Br4923 KTSMDAIAAEAQISKPMLYLYYGSKEDLFGACLNREMS-RFIAMVRADID
MUL_1163|M.ulcerans_Agy99 ETSMDTIAAAAQISKPMLYLYYGSKEDLFGACLNREMS-RFIDAVRADID
Mflv_3251|M.gilvum_PYR-GCK QVTTNLIADRAGISKGSIYQYFSDKEEIIEAAVEHLAA-QQAPEIEEMLR
MAV_4678|M.avium_104 ALSMDEIAAEIGVSKTVLYRYFVDKNDLTTAVMMRFTQTTLIPNMAAALT
TH_1623|M.thermoresistible__bu SVTYRALAAKAGVTPSLVQYYFPTLDDIFIAAIRRYSE-RNIAQLNKVLA
: :* :: : *: . : : .
Mvan_0955|M.vanbaalenii_PYR-1 ER-LDQP--APDYVRESIAALIEALDVHPEFLRAVMEQTPRLG--TGSKL
MMAR_0684|M.marinum_M SL-VRSE--HDVPLSAAIEAQVDAMLERPQILRVISGQLPGRT--SADVL
MAB_3372|M.abscessus_ATCC_1997 AG-LPDT--IEDTVRVFVGSAIANHRDSPRLHRVLFEEAPRPP--EFLAM
MSMEG_6532|M.smegmatis_MC2_155 EL-RHETPEFDQTLRSILAVVVDLHHDRPALHRLMHRVAVPRD--DQLAA
Mb1561|M.bovis_AF2122/97 RVGGSTEAPLRALLQAAVQATFEFFETDKATVKLLFRDAYALGGRFEEHL
Rv1534|M.tuberculosis_H37Rv RVGGSTEAPLRALLQAAVQATFEFFETDKATVKLLFRDAYALGGRFEEHL
MLBr_02568|M.leprae_Br4923 FT-----QSPKDLLRNTIVSFLRYIDANRASWIVMYIQAMSLP-AFAQTV
MUL_1163|M.ulcerans_Agy99 LS-----QSPKDLLRNAIVSFLRYIDQNQASWIVMYTQAVSSQ-AFAQTV
Mflv_3251|M.gilvum_PYR-GCK SVTMSRP---EVAMESSIDILIDFTIANRRLIRYLAERPDHVR--TFEAI
MAV_4678|M.avium_104 SG-----LDGFDLTREVIRVYVETVANEPEPYRFVMSNSSASK----SKV
TH_1623|M.thermoresistible__bu ER-------ADDPLRALWEYSWDEATGALMTEFMALGNHRKNIRSEIASA
Mvan_0955|M.vanbaalenii_PYR-1 VAFEQRIGELTVAYLTINKRQVRTDVTVDVAAWMLVR-MVEHLCVRYILD
MMAR_0684|M.marinum_M RPLRELMTATIKGYAIAAPDQS-IDMDVDAATWIIVQ-LLG-STIRYVVD
MAB_3372|M.abscessus_ATCC_1997 LHRSEDAVIAAAEAVLAAHPEVR-VTETDTAARMVVA-TIESLVHRLIAG
MSMEG_6532|M.smegmatis_MC2_155 LQEFENRLAGEVAFHLVRCGRVRDPDDASATARTVVH-AVDAHLHRVLP-
Mb1561|M.bovis_AF2122/97 GGIYERFIDDIEAVVVAAQRRGEVVEAPSRMAAYTLAALVGQLAHRRLNT
Rv1534|M.tuberculosis_H37Rv GGIYERFIDDIEAVVVAAQRRGEVVEAPSRMAAYTLAALVGQLAHRRLNT
MLBr_02568|M.leprae_Br4923 REARDQITELVAGLMRVGTRSSRPDHEYEIMAGALVG--AGEAMATRLTT
MUL_1163|M.ulcerans_Agy99 REGREQIVELVAGMLRAGTRSPRSDAEIDMMAAALVG--AGEAVANRLSA
Mflv_3251|M.gilvum_PYR-GCK SGLNATLLAMATLHMGHYRDQYRDELSPRALAWLFFN-MAVATTLRYIEA
MAV_4678|M.avium_104 IADSERIIARMLAVLMRRRMQHAGMDTGGVEPWAYLIVGGVQLATHSWMS
TH_1623|M.thermoresistible__bu TRKVRKIQLDALSAKFGKDARLGAEFDLSLPALQLLLSGLPKLLNLEAGV
. .
Mvan_0955|M.vanbaalenii_PYR-1 QPSIEREKFIDEVTLMALNYLRPWPTPPEDCFGSPR--------------
MMAR_0684|M.marinum_M EPPIAKDVFVTEMTRFVMSSPVAWRCSARPAAVPTA--------------
MAB_3372|M.abscessus_ATCC_1997 PRPIDPQLFEDQLVDMLTRYLTG---------------------------
MSMEG_6532|M.smegmatis_MC2_155 HREVTREAAVDDLVDLVERLLRP---------------------------
Mb1561|M.bovis_AF2122/97 DDNVTAAQVADFVVSLVLDGLRPRALAVGARGGRAART------------
Rv1534|M.tuberculosis_H37Rv DDNVTAAQVADFVVSLVLDGLRPRALAVGARGGRAART------------
MLBr_02568|M.leprae_Br4923 GD-IAVDEAAELMINLFWHGLKGAPADRDFGPSIVAG-------------
MUL_1163|M.ulcerans_Agy99 GD-TDVDEAAEMMIDLLWRGLKGAPSDREIGSNFAAG-------------
Mflv_3251|M.gilvum_PYR-GCK DDPISLDELRSGLKFASTGLLAGAVSGGHVGEPGPS--------------
MAV_4678|M.avium_104 YPRMSRDELIDYLTMLSWNALKGIVEVGGSLEKFREEPHPSPIVPPREAA
TH_1623|M.thermoresistible__bu GVKTAHHEMAAAFERYMDALQPTAGTAETKTGAKSTPQRKSAAHRPKSPG
.
Mvan_0955|M.vanbaalenii_PYR-1 -
MMAR_0684|M.marinum_M -
MAB_3372|M.abscessus_ATCC_1997 -
MSMEG_6532|M.smegmatis_MC2_155 -
Mb1561|M.bovis_AF2122/97 -
Rv1534|M.tuberculosis_H37Rv -
MLBr_02568|M.leprae_Br4923 -
MUL_1163|M.ulcerans_Agy99 -
Mflv_3251|M.gilvum_PYR-GCK -
MAV_4678|M.avium_104 L
TH_1623|M.thermoresistible__bu H