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VADGITAREAKRLQTRERLLGAAIAEFKRAGMAEADVSTIVGAAGVAHGTFFFHFPTKEHVLLELERREE DRIAKRFATFTKTHHDLSAVLREAADLVLGLERRLGVVLFKDFLALHFSPTRPPAEHGGDHPVVVLVAAQ IEHARQRGETAADVTPMNSAIYFLLGLYALLVTTDESTGRSVLVTDYLTRTLRSLQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4907 | - | - | 100% (196) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1774 | - | 2e-56 | 56.02% (191) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1253 | - | 2e-54 | 57.67% (189) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3605 | - | 6e-05 | 32.88% (73) | transcriptional regulatory protein TetR-family |
| M. tuberculosis H37Rv | Rv1255c | - | 4e-05 | 25.90% (139) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1379c | - | 3e-06 | 30.77% (65) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0249 | - | 6e-39 | 44.21% (190) | TetR family transcriptional regulator |
| M. avium 104 | MAV_2459 | - | 1e-75 | 71.94% (196) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6604 | - | 2e-76 | 71.79% (195) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_1661 | - | 5e-73 | 69.74% (195) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_4864 | - | 6e-40 | 44.74% (190) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1513 | - | 1e-95 | 88.27% (196) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4907|M.gilvum_PYR-GCK ----------MADGITAREAKRLQTRERLLGAAIAEFKRAGMAEADVSTI
Mvan_1513|M.vanbaalenii_PYR-1 ----------MADGITAREAKRLQTRERLLGAAIAEFKRAGKDESDVGAI
MAV_2459|M.avium_104 ----------MADRLSAREAKRLQTRERLMGAAIAEFARAGMAEADVGAI
MSMEG_6604|M.smegmatis_MC2_155 --------MAGADGLTAREAKRLQTRERLMGAAIAEFKRAGMADADVGTI
TH_1661|M.thermoresistible__bu --------MARAEKPSAREAKRLQTRERLLGAAIAEFKRTGMAEADVRAI
MMAR_0249|M.marinum_M MGSTASTTAPHSPQQKVREAQRLRTRARVFDAAVAEIGRRGLAGADVAAI
MUL_4864|M.ulcerans_Agy99 MGSTASTTAAHSPQQKVREAQRLRTRARVFDAAVAEIGRRGLAGADVAAI
Rv1255c|M.tuberculosis_H37Rv --------MAGTDWLSARRTE--LAADRILDAAERLFTQRDPASIGMNEI
MAB_1379c|M.abscessus_ATCC_199 ----------MPEQLSRFERRKQETRREILGAALACFAERGYHATGIADI
Mb3605|M.bovis_AF2122/97 --------MAVLAESELGSEAQRERRKRILDATMAIASKGGYEAVQMRAV
.::.*: . . : :
Mflv_4907|M.gilvum_PYR-GCK VGAAGVAHGTFFFHFPTKEHVLLELERREEDRIAKRFATFTKTHHDLSAV
Mvan_1513|M.vanbaalenii_PYR-1 VAAAGVAHGTFFFHFPTKEHVLLELERREEDRMAKRFATFTKTHHDLASA
MAV_2459|M.avium_104 VAAAGVAHGTFFFHFPTKEHVLLELERREEERIAKQFAQFLKSEHDLASA
MSMEG_6604|M.smegmatis_MC2_155 VAAAGVAHGTFFFHFPTKEHVLLELEQREEERIAKQFAQFVKKPHDLEAA
TH_1661|M.thermoresistible__bu VAAAGVAHGTFFFHFPTKEHVLLELERREEERIARQFSRFLETEHDLVGT
MMAR_0249|M.marinum_M AAAAGVARGTFYFHFPTKEHVLVELERAEELAIVAKLRDPTADPTDLVSV
MUL_4864|M.ulcerans_Agy99 AAAAGVARGTFYFHFPTKEHVLVELERAEELAIVAKLRDPTADSTDLVSV
Rv1255c|M.tuberculosis_H37Rv AKAAGCSRATLYRYFDSREALRTAYVHRETRRLGR------EIMVKIADV
MAB_1379c|M.abscessus_ATCC_199 VRRVGIAQGTFYLYFQSKREIVEQILDDLMERLSAALLDLPPSAPTSLAE
Mb3605|M.bovis_AF2122/97 ADRADVAVGTLYRYFPSKVHLLVSALGREFSRIDAKTDRSAVAGATPFQR
. .. : .*:: :* :: : :
Mflv_4907|M.gilvum_PYR-GCK LREAADLVLGLERRLGVVLFKDFLALHFSPTRPPAEHGGDHPVVVLVAAQ
Mvan_1513|M.vanbaalenii_PYR-1 LREAAHLVMGLERRLGVVLFKDFLALHFSPTRPPAEHGDDHPLVVLVADQ
MAV_2459|M.avium_104 LNEAVRLVVGLERRLGDMLFNDFLALHFSQTRPQTEDGRDHPLIVLVANE
MSMEG_6604|M.smegmatis_MC2_155 LREIVRLVIGLERRLGDLLFKDFLALHFSQTRPRVDEGMEHPVIARVTEE
TH_1661|M.thermoresistible__bu LKEAVRLVLDIEDRLGPVLFKDFLALHFSPTRPPAEEGQDHPLIVSVAEE
MMAR_0249|M.marinum_M LSSLVHQVVAVERRLGPVVFRDMLGLHFAPTRPVEDQLGEHPLAEFVIET
MUL_4864|M.ulcerans_Agy99 LSSLAHQVVAVERRLGPLVFRDMLGLHFAPTRPVEDQLGEHPLAEFVIET
Rv1255c|M.tuberculosis_H37Rv VEPAERLLVSITTTLRMVRDNPALAAWFTTTRPPIG--GEMAGRSEVIAA
MAB_1379c|M.abscessus_ATCC_199 YRDQAEHISTSLTGVLSADPQAARFLLLQAAAVDDDMAERVLAFYDAAAA
Mb3605|M.bovis_AF2122/97 LNFMVGKLNRAMQRNPLLTEAMTRAYVFADASAASEVDQVEKLIDSMFAR
: : :
Mflv_4907|M.gilvum_PYR-GCK IEHARQRGETAADVTPMN-SAIYFLLGLYALLVTTDEST---GRSVLVTD
Mvan_1513|M.vanbaalenii_PYR-1 IDNARQRGDTAADVTPMN-SAIYFLLGLYALLITTDDST---GRRELVDD
MAV_2459|M.avium_104 IEGAQQRGETDPHVNPMN-SAVFFLLGLYALLITTNHWP---TGHALLED
MSMEG_6604|M.smegmatis_MC2_155 IEAARQRGDVAADVNPVN-SAVFFLLGFYALLVTTNDWP---TRDEVLDD
TH_1661|M.thermoresistible__bu IERAQRAGEVDAEVNPWN-SAVFFLLGLYALLTTTHAWP---NRAGMVDD
MMAR_0249|M.marinum_M IARAQRANRVPPDADAGE-LGVIFLTGLFALLATGATTPD--ARTALLNR
MUL_4864|M.ulcerans_Agy99 IAQAQRADRVAPDADAGE-LGVIFLTGLFALLATGATTPD--ARTALLNG
Rv1255c|M.tuberculosis_H37Rv LAAAFLNSLGPDDPTTVERRARWVVRMLTSLLMFPGRDEA--DERAMIAE
MAB_1379c|M.abscessus_ATCC_199 IQATYLQHGISAGYFRSDLDAGHAARAVNGMLLASAFYSLRDPSPAAFEQ
Mb3605|M.bovis_AF2122/97 AMAN--GEPTEDQYHIARVISDVWLSNLLAWLTRRASATDVSKRLDLAVR
. . . *
Mflv_4907|M.gilvum_PYR-GCK YLTRTLRSLQ-------------
Mvan_1513|M.vanbaalenii_PYR-1 YLTRTLRSLQ-------------
MAV_2459|M.avium_104 YVARTLRSLKP------------
MSMEG_6604|M.smegmatis_MC2_155 YVRRTLRSMRP------------
TH_1661|M.thermoresistible__bu FVANTLRSLRPRLTRR-------
MMAR_0249|M.marinum_M FVTTVVHGMEAR-----------
MUL_4864|M.ulcerans_Agy99 FVTTVVHGMEAR-----------
Rv1255c|M.tuberculosis_H37Rv FVVPIVTPASAAARKAGHPGPE-
MAB_1379c|M.abscessus_ATCC_199 LAHAVREILYYGLASDHHPQIAD
Mb3605|M.bovis_AF2122/97 LLIGDQDSA--------------