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DRASFDRLFDMTDRTVVVTGGTRGIGLALAEGYALAGARVVVASRKADACEQAAHHLRELGAQAIGVPTH LGQVDDLGALVERTVAEFGGLDVLVNNAANPLAQPFGHMTVDALSKSFEVNLQGPVMLTQEALPHLKASD HAAVLNMVSVGAFIFAPMLSIYASMKAAMMSFTRSMAAEFVHDGIRVNALAPGPVDTDMMRKNPQEAIDG MVGGTLVGRLASADEMVGAALLLTSDAGSYITGQVIIADGGGTPR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4818 | - | - | 100% (256) | short-chain dehydrogenase/reductase SDR |
| M. gilvum PYR-GCK | Mflv_1202 | - | 5e-39 | 37.90% (248) | short-chain dehydrogenase/reductase SDR |
| M. gilvum PYR-GCK | Mflv_1263 | - | 2e-34 | 36.25% (251) | short-chain dehydrogenase/reductase SDR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2788c | fabG | 3e-37 | 35.80% (243) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. tuberculosis H37Rv | Rv2766c | fabG | 3e-37 | 35.80% (243) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 3e-22 | 29.41% (238) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_0164 | - | 6e-87 | 62.50% (248) | short chain dehydrogenase/reductase |
| M. marinum M | MMAR_4927 | - | 3e-35 | 35.08% (248) | dehydrogenase/reductase |
| M. avium 104 | MAV_3655 | fabG | 3e-38 | 35.80% (243) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. smegmatis MC2 155 | MSMEG_1740 | - | 1e-108 | 76.95% (256) | dehydrogenase/reductase SDR family protein member 4 |
| M. thermoresistible (build 8) | TH_2589 | - | 1e-108 | 76.95% (256) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_4384 | - | 1e-36 | 36.14% (249) | short-chain type dehydrogenase/reductase |
| M. vanbaalenii PYR-1 | Mvan_1624 | - | 1e-133 | 92.97% (256) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4818|M.gilvum_PYR-GCK -------MDRASFDRLFDMTDRTVVVTGGTRGIGLALAEGYALAGARVVV
Mvan_1624|M.vanbaalenii_PYR-1 -------MDRASFDRLFDMTDRTVVVTGGTRGIGLALAEGYVLAGARVVV
MSMEG_1740|M.smegmatis_MC2_155 -------MDRQRFERLFDMSDRTVIVTGGTRGIGLSLAEGFVLAGARVVV
TH_2589|M.thermoresistible__bu -------VDRQTFDKLFDMTGRTVVVTGGTRGIGLALAEGYVLAGARVVV
MAB_0164|M.abscessus_ATCC_1997 -------MNLTDFQSLYDLSGRTAIVTGGTRGIGYAIAEALGACGASVVV
Mb2788c|M.bovis_AF2122/97 -------------MTSLDLTGRTAIITGASRGIGLAIAQQLAAAGAHVVL
Rv2766c|M.tuberculosis_H37Rv -------------MTSLDLTGRTAIITGASRGIGLAIAQQLAAAGAHVVL
MAV_3655|M.avium_104 -------------MTSQDLTGRTAIITGASRGIGLAIAQQLAAAGANVVL
MUL_4384|M.ulcerans_Agy99 ---------MGYADQLFDLTDHVVLITGGSRGLGRQMAFAAARCGANVVI
MMAR_4927|M.marinum_M ---------------MGQFENKVAIVTGAAQGIGQAYADALAREGARVVV
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
: .: ::**. :*:* * * *.:
Mflv_4818|M.gilvum_PYR-GCK ASRKADACEQAAHHLR-ELGAQAIGVPTHLGQVDDLGALVERTVAEFGGL
Mvan_1624|M.vanbaalenii_PYR-1 ASRKADACEETARHLR-ELGGSAIGVPTHLGEVDDLGALVERTVAEFGGV
MSMEG_1740|M.smegmatis_MC2_155 ASRKPDACETAAAHLR-ELGGDAVGVPAHTGDVDDLGAVVERAVSEFGGV
TH_2589|M.thermoresistible__bu ASRKSDACERAAAHLR-ALGGDAIGVPTHLGDIDACEALVRRTVDEFGGI
MAB_0164|M.abscessus_ATCC_1997 SSRKSDACTAAAKELH-DKGYRALGVPAHMGELGDIDALVTATVDEYGGV
Mb2788c|M.bovis_AF2122/97 TARRQE----AADEAAAQVGDRALGVGAHAVDEDAARRCVDLTLERFGSV
Rv2766c|M.tuberculosis_H37Rv TARRQE----AADEAAAQVGDRALGVGAHAVDEDAARRCVDLTLERFGSV
MAV_3655|M.avium_104 TARKQE----AADEAAAQVGPQALGVGAHAVDEDAARQCVQLTLERFGSV
MUL_4384|M.ulcerans_Agy99 ASRNLDNCVATATEIESETGRSALAYQVHVGRWDQLDGLVAASYERFGKI
MMAR_4927|M.marinum_M ADINAEAAEKTAKQIV-ADGGTAIHVPVDVSDEESARAMADRTVSEFGGI
MLBr_01807|M.leprae_Br4923 T------------HRASVVPDWFFGVECDVTDNDAIGAAFKAVEEHQGPV
: . . . . * :
Mflv_4818|M.gilvum_PYR-GCK DVLVNNAAN---PLAQPFGHMTVDALSKSFEVNLQGPVMLTQEALPHLKA
Mvan_1624|M.vanbaalenii_PYR-1 DVLVNNAAN---PLAQPFGYMTVDALTKSFEVNLRGPVMLVQEALPHLKA
MSMEG_1740|M.smegmatis_MC2_155 DVVVNNAAN---ALAQPLGKMTPEAWAKSYEVNLRGPVFLVQHALPYLQK
TH_2589|M.thermoresistible__bu DVLVNNAAN---ALTQPLGELTVDAWTKSFEVNLRGPVFLVQAALPHLKT
MAB_0164|M.abscessus_ATCC_1997 DIVVNAAAN---PVAQPMGSYTPEALGKSFDVNVRGPVFLVQAALPHLTA
Mb2788c|M.bovis_AF2122/97 DILINNAGTN--PAYGPLLEQDHARFAKIFDVNLWAPLMWTSLVVTAWMG
Rv2766c|M.tuberculosis_H37Rv DILINNAGTN--PAYGPLLEQDHARFAKIFDVNLWAPLMWTSLVVTAWMG
MAV_3655|M.avium_104 DILVNNAGTN--PAYGPLIEQDHARFAKIFDVNLWAPLLWTSLAVKSWMG
MUL_4384|M.ulcerans_Agy99 DTLINNAGMS--PLYDKLSDVTEKLFDAVLNLNLKGPFRLSALVGERMVA
MMAR_4927|M.marinum_M DYLVNNAAIYGGMKLDLLLTVPLDYYKKFMSVNHDGVLVCTRAVYKHMAK
MLBr_01807|M.leprae_Br4923 EVLVANAGIT---SDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIK
: :: *. : .:* . . .
Mflv_4818|M.gilvum_PYR-GCK SDHAAVLNMVSVGAFIFAPMLSIYASMKAAMMSFTRSMAAEFVHDGIRVN
Mvan_1624|M.vanbaalenii_PYR-1 SEHAAVLNMVSVGAFIFAPMLSIYASMKAAMMSFTRSMAAEFVHHGIRVN
MSMEG_1740|M.smegmatis_MC2_155 SQNAAVLNMVSVGAFNFAPALSIYASSKAALMSVTRSMAAEFAPSGIRVN
TH_2589|M.thermoresistible__bu SPHAAVLNMVSVGAFLFSPGTAMYSAGKAALMSFTRSMAAQFAPLGIRVN
MAB_0164|M.abscessus_ATCC_1997 SEHASVLNVVSVAAFQYVPMLSMYAAMKATLMSFTRSMAAEYTARGIRVN
Mb2788c|M.bovis_AF2122/97 EHGGAVVNTASIGGMHQSPAMGMYNATKAALIHVTKQLALELSPR-IRVN
Rv2766c|M.tuberculosis_H37Rv EHGGAVVNTASIGGMHQSPAMGMYNATKAALIHVTKQLALELSPR-IRVN
MAV_3655|M.avium_104 EHGGSIVNTASIGGLHQSPAMGMYNATKAALIHVTKQLALELSPR-VRVN
MUL_4384|M.ulcerans_Agy99 ADGGSIINVSSAGSLRPSADIIPYAAAKAGLNAMTEGLARAFGPT-VRVN
MMAR_4927|M.marinum_M RGGGAIVNQSSTAAWLYS---NFYGLAKVGVNGLTQQLSRELGGMKIRIN
MLBr_01807|M.leprae_Br4923 QRFGRYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSITAN
. : * . * * : .:. :: : *
Mflv_4818|M.gilvum_PYR-GCK ALAPGPVDTDMMRKNPQEAIDG-MVGGTLVGRLASADEMVGAALLLTSDA
Mvan_1624|M.vanbaalenii_PYR-1 ALAPGPVDTDMMRKNPQEAIDG-MVGGTLLGRLATPDEMVGAALLLTSDA
MSMEG_1740|M.smegmatis_MC2_155 ALAPGPVDTDMMRKNPQEAIDA-MTAGTLMKRLAHPDEMVGAALLLCSDA
TH_2589|M.thermoresistible__bu ALAPGPVDTDMMRNNPQEVVDM-MAGATLMKRLATPDEMVGAALLLTSDA
MAB_0164|M.abscessus_ATCC_1997 ALAPGTVDTYMLQQNPQEIIDA-MAAQSFMGRVAHTDEMIGPALLLLSDA
Mb2788c|M.bovis_AF2122/97 AICPGVVRTRLAEALWKDHEDP-LAATIALGRIGEPADIASAVAFLVSDA
Rv2766c|M.tuberculosis_H37Rv AICPGVVRTRLAEALWKDHEDP-LAATIALGRIGEPADIASAVAFLVSDA
MAV_3655|M.avium_104 AIAPGVVRTRLAEALWKDHEDP-LSSSIALGRIGEPIDVAAAVAFLVSDA
MUL_4384|M.ulcerans_Agy99 TLMAGPFLTDVSKAWNLDAATQNPFGHLALRRAGNPPEIVGAALFLASDA
MMAR_4927|M.marinum_M AIAPGPIDTEATRTVTPGEFVKDMVKQIPLSRMGTPEDLVGMCLFLLGDQ
MLBr_01807|M.leprae_Br4923 VVAPGFIDTEMTRAMDSKYQEA-ALQAIPLGRIGAVEEIAGAVSFLASED
.: .* . * . : * . :: . :* .:
Mflv_4818|M.gilvum_PYR-GCK GSYITGQVIIADGGG-TPR------------
Mvan_1624|M.vanbaalenii_PYR-1 GSYITGQVIIADGGG-TPR------------
MSMEG_1740|M.smegmatis_MC2_155 GSYMTGQVVIVDGGG-TPR------------
TH_2589|M.thermoresistible__bu GSYITGTVLIADGGG-TPR------------
MAB_0164|M.abscessus_ATCC_1997 GSFITGQVIVADGGGGVQR------------
Mb2788c|M.bovis_AF2122/97 ASWITGETMIIDGGLLLGNALGFRAAPSTEH
Rv2766c|M.tuberculosis_H37Rv ASWITGETMIIDGGLLLGNALGFRAAPSTEH
MAV_3655|M.avium_104 ASWITGETLVIDGGTVLGAAQGFRSAPTPS-
MUL_4384|M.ulcerans_Agy99 SSFTTGSILRADGGIP---------------
MMAR_4927|M.marinum_M ASWITGQIFNVDGGQIIRS------------
MLBr_01807|M.leprae_Br4923 AGYISGAVIPVDGGLGMGH------------
..: :* . ***