For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VDRQRFERLFDMSDRTVIVTGGTRGIGLSLAEGFVLAGARVVVASRKPDACETAAAHLRELGGDAVGVPA HTGDVDDLGAVVERAVSEFGGVDVVVNNAANALAQPLGKMTPEAWAKSYEVNLRGPVFLVQHALPYLQKS QNAAVLNMVSVGAFNFAPALSIYASSKAALMSVTRSMAAEFAPSGIRVNALAPGPVDTDMMRKNPQEAID AMTAGTLMKRLAHPDEMVGAALLLCSDAGSYMTGQVVIVDGGGTPR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1740 | - | - | 100% (256) | dehydrogenase/reductase SDR family protein member 4 |
| M. smegmatis MC2 155 | MSMEG_4850 | - | 8e-39 | 38.78% (245) | short-chain dehydrogenase/reductase SDR |
| M. smegmatis MC2 155 | MSMEG_0779 | - | 8e-37 | 37.80% (246) | short chain dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2788c | fabG | 8e-40 | 36.63% (243) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. gilvum PYR-GCK | Mflv_4818 | - | 1e-108 | 76.95% (256) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv2766c | fabG | 9e-40 | 36.63% (243) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 3e-25 | 31.09% (238) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_0833 | - | 2e-85 | 61.51% (252) | Short-chain dehydrogenase/reductase |
| M. marinum M | MMAR_1952 | fabG | 1e-38 | 35.80% (243) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_3655 | fabG | 2e-40 | 36.21% (243) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. thermoresistible (build 8) | TH_2589 | - | 1e-109 | 75.78% (256) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_2173 | fabG | 3e-38 | 35.39% (243) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. vanbaalenii PYR-1 | Mvan_1624 | - | 1e-112 | 79.30% (256) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4818|M.gilvum_PYR-GCK -------MDRASFDRLFDMTDRTVVVTGGTRGIGLALAEGYALAGARVVV
Mvan_1624|M.vanbaalenii_PYR-1 -------MDRASFDRLFDMTDRTVVVTGGTRGIGLALAEGYVLAGARVVV
MSMEG_1740|M.smegmatis_MC2_155 -------MDRQRFERLFDMSDRTVIVTGGTRGIGLSLAEGFVLAGARVVV
TH_2589|M.thermoresistible__bu -------VDRQTFDKLFDMTGRTVVVTGGTRGIGLALAEGYVLAGARVVV
MAB_0833|M.abscessus_ATCC_1997 -------MNRETFSRLFDLTGRTAIVTGGTRGIGRALAEGYACAGANVVV
Mb2788c|M.bovis_AF2122/97 -------MTS------LDLTGRTAIITGASRGIGLAIAQQLAAAGAHVVL
Rv2766c|M.tuberculosis_H37Rv -------MTS------LDLTGRTAIITGASRGIGLAIAQQLAAAGAHVVL
MMAR_1952|M.marinum_M -------MTS------LDLTGRTAIITGASRGIGLAIAQRLAGAGANVVL
MUL_2173|M.ulcerans_Agy99 -------MTS------LDLTGRTAIITGASRGIGLAIAQRLAGAGANVVL
MAV_3655|M.avium_104 -------MTS------QDLTGRTAIITGASRGIGLAIAQQLAAAGANVVL
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
: : .*: ::**..**** ::*. . * .*.:
Mflv_4818|M.gilvum_PYR-GCK ASRKADACEQAAHHLRELGAQAIGVPTHLGQVDDLGALVERTVAEFGGLD
Mvan_1624|M.vanbaalenii_PYR-1 ASRKADACEETARHLRELGGSAIGVPTHLGEVDDLGALVERTVAEFGGVD
MSMEG_1740|M.smegmatis_MC2_155 ASRKPDACETAAAHLRELGGDAVGVPAHTGDVDDLGAVVERAVSEFGGVD
TH_2589|M.thermoresistible__bu ASRKSDACERAAAHLRALGGDAIGVPTHLGDIDACEALVRRTVDEFGGID
MAB_0833|M.abscessus_ATCC_1997 ASRKPEACTEAVERLRSLGARALGVPTHTGDIHSLEELVRATAEEFGGID
Mb2788c|M.bovis_AF2122/97 TARRQEAADEAAAQV---GDRALGVGAHAVDEDAARRCVDLTLERFGSVD
Rv2766c|M.tuberculosis_H37Rv TARRQEAADEAAAQV---GDRALGVGAHAVDEDAARRCVDLTLERFGSVD
MMAR_1952|M.marinum_M TARKQESADAAAAEV---GERAVGVGAHAVDEEAARGCVDLALERFGSVD
MUL_2173|M.ulcerans_Agy99 TARKQESADAAAAEV---GERAVGVGAHAVDEEAARGCVDLALERFGSVD
MAV_3655|M.avium_104 TARKQEAADEAAAQV---GPQALGVGAHAVDEDAARQCVQLTLERFGSVD
MLBr_01807|M.leprae_Br4923 THRASVVP-----------DWFFGVECDVTDNDAIGAAFKAVEEHQGPVE
: * .** . : . . . . * ::
Mflv_4818|M.gilvum_PYR-GCK VLVNNA-ANPLAQPFGHMTVDALSKSFEVNLQGPVMLTQEALPHLKASDH
Mvan_1624|M.vanbaalenii_PYR-1 VLVNNA-ANPLAQPFGYMTVDALTKSFEVNLRGPVMLVQEALPHLKASEH
MSMEG_1740|M.smegmatis_MC2_155 VVVNNA-ANALAQPLGKMTPEAWAKSYEVNLRGPVFLVQHALPYLQKSQN
TH_2589|M.thermoresistible__bu VLVNNA-ANALTQPLGELTVDAWTKSFEVNLRGPVFLVQAALPHLKTSPH
MAB_0833|M.abscessus_ATCC_1997 IVVNNA-ANALTEPVGAFTVDGWDKSFGVNLRGPVFLVQAALPHLVASPH
Mb2788c|M.bovis_AF2122/97 ILINNAGTNPAYGPLLEQDHARFAKIFDVNLWAPLMWTSLVVTAWMGEHG
Rv2766c|M.tuberculosis_H37Rv ILINNAGTNPAYGPLLEQDHARFAKIFDVNLWAPLMWTSLVVTAWMGEHG
MMAR_1952|M.marinum_M ILINNAGTNPAYGPLIEQDHARFTKIFDVNLWAPLMWTSLVVKAWMGEHG
MUL_2173|M.ulcerans_Agy99 ILINNAGTNPAYGPLIEQDHARFTKIFDVNLWAPLMWTSLVVKAWMGEHG
MAV_3655|M.avium_104 ILVNNAGTNPAYGPLIEQDHARFAKIFDVNLWAPLLWTSLAVKSWMGEHG
MLBr_01807|M.leprae_Br4923 VLVANA-GITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQRF
::: ** . . * *** . . .. . .
Mflv_4818|M.gilvum_PYR-GCK AAVLNMVSVGAFIFAPMLSIYASMKAAMMSFTRSMAAEFVHDGIRVNALA
Mvan_1624|M.vanbaalenii_PYR-1 AAVLNMVSVGAFIFAPMLSIYASMKAAMMSFTRSMAAEFVHHGIRVNALA
MSMEG_1740|M.smegmatis_MC2_155 AAVLNMVSVGAFNFAPALSIYASSKAALMSVTRSMAAEFAPSGIRVNALA
TH_2589|M.thermoresistible__bu AAVLNMVSVGAFLFSPGTAMYSAGKAALMSFTRSMAAQFAPLGIRVNALA
MAB_0833|M.abscessus_ATCC_1997 AAVLNVVSVGAFMFGQGVSMYSAAKAALVSYTRSAAAELASRGVRVNALA
Mb2788c|M.bovis_AF2122/97 GAVVNTASIGGMHQSPAMGMYNATKAALIHVTKQLALELSPR-IRVNAIC
Rv2766c|M.tuberculosis_H37Rv GAVVNTASIGGMHQSPAMGMYNATKAALIHVTKQLALELSPR-IRVNAIC
MMAR_1952|M.marinum_M GVVINTASIGGMHQSPAMGMYNATKAALIHVTKQLALELSPR-VRVNAIC
MUL_2173|M.ulcerans_Agy99 GVVINTASIGGMHQSPAMGMYNATNAALIHVTKQLALELSPR-VRVNAIC
MAV_3655|M.avium_104 GSIVNTASIGGLHQSPAMGMYNATKAALIHVTKQLALELSPR-VRVNAIA
MLBr_01807|M.leprae_Br4923 GRYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSITANVVA
. : *: .: . * : ::.:: ::. * :: : .*.:.
Mflv_4818|M.gilvum_PYR-GCK PGPVDTDMMRKNPQEAIDGMVGGTLVGRLASADEMVGAALLLTSDAGSYI
Mvan_1624|M.vanbaalenii_PYR-1 PGPVDTDMMRKNPQEAIDGMVGGTLLGRLATPDEMVGAALLLTSDAGSYI
MSMEG_1740|M.smegmatis_MC2_155 PGPVDTDMMRKNPQEAIDAMTAGTLMKRLAHPDEMVGAALLLCSDAGSYM
TH_2589|M.thermoresistible__bu PGPVDTDMMRNNPQEVVDMMAGATLMKRLATPDEMVGAALLLTSDAGSYI
MAB_0833|M.abscessus_ATCC_1997 PGAIDTDMVRKTPPAEVERMANTNHLKRLGLPDEMVGTALLLTSDAGSYI
Mb2788c|M.bovis_AF2122/97 PGVVRTRLAEALWKDHEDPLAATIALGRIGEPADIASAVAFLVSDAASWI
Rv2766c|M.tuberculosis_H37Rv PGVVRTRLAEALWKDHEDPLAATIALGRIGEPADIASAVAFLVSDAASWI
MMAR_1952|M.marinum_M PGVVRTKLAEALWKDHEDPLAANIALGRIGEPVDVAEAVGFLVSDAASWI
MUL_2173|M.ulcerans_Agy99 PGVVRTKLAEALWKDHEDPLAANIALGRIGEPVDVAEAVGFLVSDAASWI
MAV_3655|M.avium_104 PGVVRTRLAEALWKDHEDPLSSSIALGRIGEPIDVAAAVAFLVSDAASWI
MLBr_01807|M.leprae_Br4923 PGFIDTEMTRAMDSKYQEAALQAIPLGRIGAVEEIAGAVSFLASEDAGYI
** : * : . : : *:. ::. :. :* *: ..::
Mflv_4818|M.gilvum_PYR-GCK TGQVIIADGGGTPR-------------
Mvan_1624|M.vanbaalenii_PYR-1 TGQVIIADGGGTPR-------------
MSMEG_1740|M.smegmatis_MC2_155 TGQVVIVDGGGTPR-------------
TH_2589|M.thermoresistible__bu TGTVLIADGGGTPR-------------
MAB_0833|M.abscessus_ATCC_1997 TGQTIIADGGLVAR-------------
Mb2788c|M.bovis_AF2122/97 TGETMIIDGGLLLGNALGFRAAPSTEH
Rv2766c|M.tuberculosis_H37Rv TGETMIIDGGLLLGNALGFRAAPSTEH
MMAR_1952|M.marinum_M TGETMVIDGGLLLGSAAGFQSRPGSAS
MUL_2173|M.ulcerans_Agy99 TGETMVIDGGLLLGSAAGFQSRPGSAS
MAV_3655|M.avium_104 TGETLVIDGGTVLGAAQGFRSAPTPS-
MLBr_01807|M.leprae_Br4923 SGAVIPVDGGLGMGH------------
:* .: ***