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RHSLIMDAVSGPKSGESLTVRRQRATKARIAAAAAEAVAAHGLAGATIEHIAAAAEVGRATFFRYFSAKE DAVVEGMAAHWLDAIADAIAAQPPELAADAAVVAAFQDLGHGFEAVSDQVRELAVMTRSSPVFSAWTLQL YLRYEAAIADLVGIRMADPAPDDPRPRLLGALAMASVRIALDDWLVHGGSLPERVRTALASLHVA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4072 | - | - | 100% (206) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3877 | - | 1e-10 | 29.74% (195) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1728 | - | 2e-09 | 29.17% (168) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0710c | - | 2e-08 | 25.58% (172) | transcriptional regulatory protein |
| M. tuberculosis H37Rv | Rv0691c | - | 2e-08 | 25.58% (172) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3837 | - | 6e-08 | 26.16% (172) | transcriptional regulatory protein TetR |
| M. marinum M | MMAR_0222 | - | 7e-62 | 60.41% (197) | TetR family transcriptional regulator |
| M. avium 104 | MAV_2512 | - | 3e-13 | 28.82% (170) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5673 | - | 9e-11 | 31.76% (170) | transcriptional regulator |
| M. thermoresistible (build 8) | TH_3524 | - | 4e-09 | 29.94% (177) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_4892 | - | 1e-60 | 58.88% (197) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_2270 | - | 4e-87 | 80.40% (199) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4072|M.gilvum_PYR-GCK MRHSLIMDAVSGPKSGESLTVRRQRATKARIAAAAAEAVAAHGLAGATIE
Mvan_2270|M.vanbaalenii_PYR-1 ------MDVVSGVDSGESLTVRKQRATKARIAAAAAQSVIDHGLAAATVE
MMAR_0222|M.marinum_M ---------MSPPPAATSLAERKRTATRQRIATAAAQLVADLGLAAATVE
MUL_4892|M.ulcerans_Agy99 ---------MSPPPAATALAERKRTATRQRIATAAAQLVADLGLVAATVE
Mb0710c|M.bovis_AF2122/97 -------------MPHESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVD
Rv0691c|M.tuberculosis_H37Rv -------------MPHESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVD
MAB_3837|M.abscessus_ATCC_1997 ------------MNAQPARVGRRPSTTRDEITAVAMTLFAQHGFDEVSVD
MAV_2512|M.avium_104 ------------MANPVGLRERRRRQTSADIRDAAVRLTLERGFDKVTVD
TH_3524|M.thermoresistible__bu ---------------------VRGHRNREALIAAAIDLFTVNGYEQTTVE
MSMEG_5673|M.smegmatis_MC2_155 ---------MAYQTQQPGLRERKKQRTRATLISAAIDLCVRQGYEQTTVE
: . : .* * .:::
Mflv_4072|M.gilvum_PYR-GCK HIAAAAEVGRATFFRYFSAKEDAVVEGMAAHWLDAIADAIAAQPPELAAD
Mvan_2270|M.vanbaalenii_PYR-1 RIAAAAEVGRATFFRYFSAKEDAVAEGMTAHWLDLITAAIAAQPPHLPAG
MMAR_0222|M.marinum_M RIADTADISRATFFRYFNSKEDAVAEGMTAHWLDRIATALAAQPEHLSAV
MUL_4892|M.ulcerans_Agy99 RIADTADISRATFFRYFNSKEDAVAEGMTAHWLDRIATALAAQPEHQSAV
Mb0710c|M.bovis_AF2122/97 DIARAAGIARRTLFRYYASK-NAIPWGDFSTHLAQLQGLLDNIDSRIQLR
Rv0691c|M.tuberculosis_H37Rv DIARAAGIARRTLFRYYASK-NAIPWGDFSTHLAQLQGLLDNIDSRIQLR
MAB_3837|M.abscessus_ATCC_1997 DIAAAAGIARRTVFRYYSSK-NAIVWGDFDSHLGVMRALLDETADTVDTS
MAV_2512|M.avium_104 EICAEAGISTRTFFNYFPNKESAIAYGPSDIPPELVADFVAAGPAPYSVV
TH_3524|M.thermoresistible__bu QIAEAAGVAPRTFFRHFAAKEDILFHGYADRLAEATRRFRAARSGSLWKA
MSMEG_5673|M.smegmatis_MC2_155 QIAAAAEVSARTFSRYFATK-DAVMLAFLDDVVDLVAGELAQQPPELGEL
*. * :. *. .:: * . : .
Mflv_4072|M.gilvum_PYR-GCK AAVVAAFQDLGHGFEA-VSDQVRELAVMTRS-SPVFSAWTLQLYLRYEAA
Mvan_2270|M.vanbaalenii_PYR-1 AALAAAFEDLGDGFDA-ISGQVRELATLTRS-SPVFSAWTLQIYLRYESA
MMAR_0222|M.marinum_M EAVVGAFGGLAVGFAE-MEDQVRELATLTRS-SETLEAWTLHIYVRYESA
MUL_4892|M.ulcerans_Agy99 EAVVGAFGGLAVGFAE-MEDQVRELATLTRS-SETLEAWTLHIYVRYESA
Mb0710c|M.bovis_AF2122/97 DALRAALLAFNTFDES-ETIRHRKRMRVILQ-TPELQAYSMTMYAGWREV
Rv0691c|M.tuberculosis_H37Rv DALRAALLAFNTFDES-ETIRHRKRMRVILQ-TPELQAYSMTMYAGWREV
MAB_3837|M.abscessus_ATCC_1997 TALRQAVLTFNDFPVD-ETPRHRMRMRMILE-VPALQAYSMLMYTGWRDV
MAV_2512|M.avium_104 LAELIALAAHHLRDVPPRREHAANMLELAKT-SPAVLAAFLADLERFQNQ
TH_3524|M.thermoresistible__bu LAEASEAVATAIAENP---GIFLVRARMYGE-LPALRATMLRINDDWIDQ
MSMEG_5673|M.smegmatis_MC2_155 DAVFCAHITAFEKTRVAMPGQLTDDRLLAAARIFTSSPSLMQATMGFRPA
* : . : :
Mflv_4072|M.gilvum_PYR-GCK IADLVGIRMADPAPDDPRPRLLGALAMASVRIALDDWLVHGG---SLPER
Mvan_2270|M.vanbaalenii_PYR-1 IAELLGPRCPDPAPDDPRPRLLGALAMASVRIALDDWLVHGG---SLPDR
MMAR_0222|M.marinum_M IADLIAPRIPNLVPQDPRPRLVGALAMAVVRIALDDWLGQGG---SLPDR
MUL_4892|M.ulcerans_Agy99 IADLIAPRIPNLVPQDPRPRLVGALAMAVVRIALDDWLGQGG---SLPDR
Mb0710c|M.bovis_AF2122/97 IAKFVARRS-GGKTTDFMPQTVAWTMLGVALSAYEHWLRDESV--SLTEA
Rv0691c|M.tuberculosis_H37Rv IAKFVARRS-GGKTTDFMPQTVAWTMLGVALSAYEHWLRDESV--SLTEA
MAB_3837|M.abscessus_ATCC_1997 IAQFVARRS-GTDPGSLLPQTVAWTLLGVALAAYEQWLADESS--KLTTL
MAV_2512|M.avium_104 LTDIIVRRQ-GMQPDDEMAPLISALALTAVRSGIEKWASGEAS--ETDDT
TH_3524|M.thermoresistible__bu MTTEVARWLGSDAAVDVRPRLAATVINGANRTAIDLWVSADGKG-DLVEL
MSMEG_5673|M.smegmatis_MC2_155 PLFEVLAKRMGVSADDRKIALIASLWNAIMTTALVQLVPDVDWATVTVER
: . . . . .
Mflv_4072|M.gilvum_PYR-GCK VRTALASLHVA---------------------
Mvan_2270|M.vanbaalenii_PYR-1 VRAALASIEVV---------------------
MMAR_0222|M.marinum_M VQQGLAAIVIA---------------------
MUL_4892|M.ulcerans_Agy99 VQQGLAAIVIA---------------------
Mb0710c|M.bovis_AF2122/97 LGAAFDVVGAGLDRLNQ---------------
Rv0691c|M.tuberculosis_H37Rv LGAAFDVVGAGLDRLNQ---------------
MAB_3837|M.abscessus_ATCC_1997 LGKGFDAAEVGLRALR----------------
MAV_2512|M.avium_104 PMPYVERAAALVNSIFTK--------------
TH_3524|M.thermoresistible__bu MADAVRLVRPTLDRIERESRTVANPVRRRDVV
MSMEG_5673|M.smegmatis_MC2_155 IVNQMRTTYAEFLEVAGRRHEFA---------
.