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PHESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAIPWGDFSTHLAQ LQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPELQAYSMTMYAGWREVIAKFVAR RSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTEALGAAFDVVGAGLDRLNQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0691c | - | - | 100% (198) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. tuberculosis H37Rv | Rv1963c | mce3R | 1e-06 | 42.59% (54) | transcriptional repressor (probably TETR-family) MCE3R |
| M. tuberculosis H37Rv | Rv0238 | - | 1e-06 | 21.94% (155) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0710c | - | 1e-111 | 100.00% (198) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_5062 | - | 1e-67 | 65.45% (191) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 2e-06 | 22.34% (188) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3837 | - | 1e-62 | 61.98% (192) | transcriptional regulatory protein TetR |
| M. marinum M | MMAR_1019 | - | 3e-85 | 78.68% (197) | transcriptional regulator |
| M. avium 104 | MAV_4481 | - | 1e-85 | 79.49% (195) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_1420 | - | 7e-72 | 68.88% (196) | transcriptional regulatory protein |
| M. thermoresistible (build 8) | TH_1899 | - | 1e-62 | 66.10% (177) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. ulcerans Agy99 | MUL_0771 | - | 2e-85 | 78.68% (197) | transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1294 | - | 1e-69 | 66.84% (190) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0691c|M.tuberculosis_H37Rv --------------------------MPHESRVGRRRSTTPHHISDVAIE
Mb0710c|M.bovis_AF2122/97 --------------------------MPHESRVGRRRSTTPHHISDVAIE
MMAR_1019|M.marinum_M --------------------------MAHESRAGRRPSTTKRHIADVAID
MUL_0771|M.ulcerans_Agy99 --------------------------MAHESRAGRRPSTTKRHIADVAID
MAV_4481|M.avium_104 --------------------------MPQQ-RVGRRRSTTPHHITDVAID
MSMEG_1420|M.smegmatis_MC2_155 --------------------------MSEGSRAGRRRSTTQDHIAGVAID
Mflv_5062|M.gilvum_PYR-GCK -------------------------MSAARPRVGRRRSTSWEHISDVAID
Mvan_1294|M.vanbaalenii_PYR-1 -------------------------MSAAKARVGRRRSTSWEHLSDVAID
TH_1899|M.thermoresistible__bu ----------------------------------------------VALD
MAB_3837|M.abscessus_ATCC_1997 -------------------------MNAQPARVGRRPSTTRDEITAVAMT
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
**
Rv0691c|M.tuberculosis_H37Rv LFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAIPWGDFSTHLAQLQ-
Mb0710c|M.bovis_AF2122/97 LFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAIPWGDFSTHLAQLQ-
MMAR_1019|M.marinum_M LFAARTFAEVSVDDVAQAAGIARRTLFRYYASKNAIPWGDFDTHLAQLQ-
MUL_0771|M.ulcerans_Agy99 LFAARTFAEVSVDDVAQAAGIARRTLFRYYASKNAIPWGDFDTHLAQLQ-
MAV_4481|M.avium_104 LFTARGFAEVSVDDVAAAAGISRRTLFRYYASKNAIPWGDFDTHLARLR-
MSMEG_1420|M.smegmatis_MC2_155 LFAARGFDAVSVDDVAAAAGISRRTLFRYYASKSAIPWGDFDSHLQHLQ-
Mflv_5062|M.gilvum_PYR-GCK LFMARGFDDVSVDDVASAAGIARRTLFRYYPSKSALPWGDFDAHLDHMR-
Mvan_1294|M.vanbaalenii_PYR-1 LFMARGFDDVSVDDVAAAAGIARRTLFRYYPSKSALPWGDFDAHLEHMR-
TH_1899|M.thermoresistible__bu LFADRGFDEVSVDDVAAAAGIGRRTLFRYYPSKNAIPWGDFDAHLDRMR-
MAB_3837|M.abscessus_ATCC_1997 LFAQHGFDEVSVDDIAAAAGIARRTVFRYYSSKNAIVWGDFDSHLGVMR-
MLBr_00815|M.leprae_Br4923 VFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLVS
:* : : ..:*::* **:.: .:::::.** : . :. *: :
Rv0691c|M.tuberculosis_H37Rv GLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMR-VILQTPELQA
Mb0710c|M.bovis_AF2122/97 GLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMR-VILQTPELQA
MMAR_1019|M.marinum_M DLLERIDGHVRLGKALREALLAFNTYDESETIRHRQRMR-IILQTAELQA
MUL_0771|M.ulcerans_Agy99 DLLERIDGHVRLGKALREALLAFNTYDESETIRHRQRMR-IILQTAELQA
MAV_4481|M.avium_104 ELLDNVESRVPLGDALRTALLAFNTFDESETARHRQRMR-VILQTAELQA
MSMEG_1420|M.smegmatis_MC2_155 NLLRTLSSEVSLGDALREALLTFNTYADHEMAEHRQRMR-VILETEELQA
Mflv_5062|M.gilvum_PYR-GCK ALLADLDPEVPIRDALRTALLAFNDF--DDPDRHRQRMR-LILETEALQA
Mvan_1294|M.vanbaalenii_PYR-1 ELLDELDPSVPIRDALRTALLAFNDF--DDADRHRQRMR-LILETEALQA
TH_1899|M.thermoresistible__bu DLLDGIGPDVPIGAALRSMLLAFNDFGEDETGRHRRRMR-VILQTDALQA
MAB_3837|M.abscessus_ATCC_1997 ALLDETADTVDTSTALRQAVLTFNDFPVDETPRHRMRMR-MILEVPALQA
MLBr_00815|M.leprae_Br4923 SVQQALRTTTNNRQRLHAAVQAFFDFIEHDGQGYRLIFENDNITEPRVAA
: *: : :* : : :* :. : : *
Rv0691c|M.tuberculosis_H37Rv YSMTMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLR
Mb0710c|M.bovis_AF2122/97 YSMTMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLR
MMAR_1019|M.marinum_M YSMTMYAGWRAVIAGFVARRLSVKPTDLVPQTVAWTMLGVALSAYEHWLS
MUL_0771|M.ulcerans_Agy99 YSMTMYAGWRAVIAGFVARRLSVKPTDLVPQTVAWTMLGVALSAYEHWLS
MAV_4481|M.avium_104 YSMTMYAGWREVIAGFVARRCECKTTDLAPQTVAWMMLGVALSAYEHWLG
MSMEG_1420|M.smegmatis_MC2_155 YSMTMYAGWRTVIAEYVADRLGMSTTDLMPQTVAWLMLGVALSAYENWLA
Mflv_5062|M.gilvum_PYR-GCK YSMTMYAGWRAVVAAFVADRLGVGGDDLRPQTVAWTMLAVSLSAYEHWLA
Mvan_1294|M.vanbaalenii_PYR-1 YSMTMYAGWRAVVAAFVAGRLGVDPAELMPQTVAWTMLAVSLSAYEYWLA
TH_1899|M.thermoresistible__bu HSMTMYAGWRAVVADFVARRLGLAPSDLVPQTVAWTMLGVALSAYAYWLA
MAB_3837|M.abscessus_ATCC_1997 YSMLMYTGWRDVIAQFVARRSGTDPGSLLPQTVAWTLLGVALAAYEQWLA
MLBr_00815|M.leprae_Br4923 QVRVATESCIDAVFALISADSRLDP--HRARMVAVGLVGISVDCARYWLD
. .: :: .: ** ::.::: . **
Rv0691c|M.tuberculosis_H37Rv D-ESVSLTEALGAAFDVVGAGLDRLNQ-----------
Mb0710c|M.bovis_AF2122/97 D-ESVSLTEALGAAFDVVGAGLDRLNQ-----------
MMAR_1019|M.marinum_M D-ESVSLPEALGNAFDVVGAGLEKLD------------
MUL_0771|M.ulcerans_Agy99 D-ESVSLPEALGNAFDVVGAGLEKLD------------
MAV_4481|M.avium_104 D-ESVPLPVALGNAFDVVGAGLNGLDR-----------
MSMEG_1420|M.smegmatis_MC2_155 D-ESVSLRGAIAAAFEVARPGLDALQPAH---------
Mflv_5062|M.gilvum_PYR-GCK D-ETACLQSSLGEAFDLLASGLSGLESGVSEFAPGARR
Mvan_1294|M.vanbaalenii_PYR-1 D-ESVSLAAALGDAFDMLASGLAGLETGVSEFGA----
TH_1899|M.thermoresistible__bu D-ESVPLAQALADAFDAIRPGLDALDG--KKFA-----
MAB_3837|M.abscessus_ATCC_1997 D-ESSKLTTLLGKGFDAAEVGLRALR------------
MLBr_00815|M.leprae_Br4923 TNRPISKSDAVEGTVQFAWGGLSHVPLTRL--------
.. : .: ** :