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MNAQPARVGRRPSTTRDEITAVAMTLFAQHGFDEVSVDDIAAAAGIARRTVFRYYSSKNAIVWGDFDSHL GVMRALLDETADTVDTSTALRQAVLTFNDFPVDETPRHRMRMRMILEVPALQAYSMLMYTGWRDVIAQFV ARRSGTDPGSLLPQTVAWTLLGVALAAYEQWLADESSKLTTLLGKGFDAAEVGLRALR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3837 | - | - | 100% (198) | transcriptional regulatory protein TetR |
| M. abscessus ATCC 19977 | MAB_3527 | - | 6e-09 | 23.84% (172) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3586c | - | 3e-08 | 39.29% (56) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0710c | - | 8e-63 | 61.98% (192) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_5062 | - | 9e-59 | 58.88% (197) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0691c | - | 9e-63 | 61.98% (192) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_01070 | - | 2e-07 | 33.01% (103) | putative TetR-family transcriptional regulator |
| M. marinum M | MMAR_1019 | - | 3e-60 | 59.49% (195) | transcriptional regulator |
| M. avium 104 | MAV_4481 | - | 3e-60 | 61.26% (191) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_1420 | - | 7e-59 | 57.65% (196) | transcriptional regulatory protein |
| M. thermoresistible (build 8) | TH_1899 | - | 3e-59 | 64.77% (176) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. ulcerans Agy99 | MUL_0771 | - | 2e-60 | 59.49% (195) | transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1294 | - | 5e-63 | 61.42% (197) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5062|M.gilvum_PYR-GCK ---------MSAARPRVGRRRS-----TSWEHISDVAIDLFMARGFDDVS
Mvan_1294|M.vanbaalenii_PYR-1 ---------MSAAKARVGRRRS-----TSWEHLSDVAIDLFMARGFDDVS
TH_1899|M.thermoresistible__bu -----------------------------------VALDLFADRGFDEVS
Mb0710c|M.bovis_AF2122/97 ----------MPHESRVGRRRS-----TTPHHISDVAIELFAAHGFTDVS
Rv0691c|M.tuberculosis_H37Rv ----------MPHESRVGRRRS-----TTPHHISDVAIELFAAHGFTDVS
MMAR_1019|M.marinum_M ----------MAHESRAGRRPS-----TTKRHIADVAIDLFAARTFAEVS
MUL_0771|M.ulcerans_Agy99 ----------MAHESRAGRRPS-----TTKRHIADVAIDLFAARTFAEVS
MAV_4481|M.avium_104 ----------MPQQ-RVGRRRS-----TTPHHITDVAIDLFTARGFAEVS
MSMEG_1420|M.smegmatis_MC2_155 ----------MSEGSRAGRRRS-----TTQDHIAGVAIDLFAARGFDAVS
MAB_3837|M.abscessus_ATCC_1997 ---------MNAQPARVGRRPS-----TTRDEITAVAMTLFAQHGFDEVS
MLBr_01070|M.leprae_Br4923 MIVVGNFTQSNYVPASRGRRSSQLSGDDREQAILAVAERLLAERPLGDFS
** *: : : .*
Mflv_5062|M.gilvum_PYR-GCK VDDVASAAGIARRTLFRYYPSKSALPWGDFDAHLDHMRALLADLDPEVPI
Mvan_1294|M.vanbaalenii_PYR-1 VDDVAAAAGIARRTLFRYYPSKSALPWGDFDAHLEHMRELLDELDPSVPI
TH_1899|M.thermoresistible__bu VDDVAAAAGIGRRTLFRYYPSKNAIPWGDFDAHLDRMRDLLDGIGPDVPI
Mb0710c|M.bovis_AF2122/97 VDDIARAAGIARRTLFRYYASKNAIPWGDFSTHLAQLQGLLDNIDSRIQL
Rv0691c|M.tuberculosis_H37Rv VDDIARAAGIARRTLFRYYASKNAIPWGDFSTHLAQLQGLLDNIDSRIQL
MMAR_1019|M.marinum_M VDDVAQAAGIARRTLFRYYASKNAIPWGDFDTHLAQLQDLLERIDGHVRL
MUL_0771|M.ulcerans_Agy99 VDDVAQAAGIARRTLFRYYASKNAIPWGDFDTHLAQLQDLLERIDGHVRL
MAV_4481|M.avium_104 VDDVAAAAGISRRTLFRYYASKNAIPWGDFDTHLARLRELLDNVESRVPL
MSMEG_1420|M.smegmatis_MC2_155 VDDVAAAAGISRRTLFRYYASKSAIPWGDFDSHLQHLQNLLRTLSSEVSL
MAB_3837|M.abscessus_ATCC_1997 VDDIAAAAGIARRTVFRYYSSKNAIVWGDFDSHLGVMRALLDETADTVDT
MLBr_01070|M.leprae_Br4923 VDELAKGAGISRPTFYFYFPSKNAVLLSLLDDLNMKSRSAVEALAEQLPA
**::* .***.* *.: *:.**.*: . :. : : :
Mflv_5062|M.gilvum_PYR-GCK R--DALRTALLAFNDF--DDPDRHRQRMRLILETEALQAYSMTMYAGWR-
Mvan_1294|M.vanbaalenii_PYR-1 R--DALRTALLAFNDF--DDADRHRQRMRLILETEALQAYSMTMYAGWR-
TH_1899|M.thermoresistible__bu G--AALRSMLLAFNDFGEDETGRHRRRMRVILQTDALQAHSMTMYAGWR-
Mb0710c|M.bovis_AF2122/97 R--DALRAALLAFNTFDESETIRHRKRMRVILQTPELQAYSMTMYAGWR-
Rv0691c|M.tuberculosis_H37Rv R--DALRAALLAFNTFDESETIRHRKRMRVILQTPELQAYSMTMYAGWR-
MMAR_1019|M.marinum_M G--KALREALLAFNTYDESETIRHRQRMRIILQTAELQAYSMTMYAGWR-
MUL_0771|M.ulcerans_Agy99 G--KALREALLAFNTYDESETIRHRQRMRIILQTAELQAYSMTMYAGWR-
MAV_4481|M.avium_104 G--DALRTALLAFNTFDESETARHRQRMRVILQTAELQAYSMTMYAGWR-
MSMEG_1420|M.smegmatis_MC2_155 G--DALREALLTFNTYADHEMAEHRQRMRVILETEELQAYSMTMYAGWR-
MAB_3837|M.abscessus_ATCC_1997 S--TALRQAVLTFNDFPVDETPRHRMRMRMILEVPALQAYSMLMYTGWR-
MLBr_01070|M.leprae_Br4923 DPAAVWRSAITAFFEVCGTHRAVAVAGAAAKATSPEVRRLWSTVMQQWID
. * : :* . :: : *
Mflv_5062|M.gilvum_PYR-GCK -AVVAAFVADRLGVGGDDLRPQTVAWTMLAVSLSAYEHWLADETACLQSS
Mvan_1294|M.vanbaalenii_PYR-1 -AVVAAFVAGRLGVDPAELMPQTVAWTMLAVSLSAYEYWLADESVSLAAA
TH_1899|M.thermoresistible__bu -AVVADFVARRLGLAPSDLVPQTVAWTMLGVALSAYAYWLADESVPLAQA
Mb0710c|M.bovis_AF2122/97 -EVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTEA
Rv0691c|M.tuberculosis_H37Rv -EVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTEA
MMAR_1019|M.marinum_M -AVIAGFVARRLSVKPTDLVPQTVAWTMLGVALSAYEHWLSDESVSLPEA
MUL_0771|M.ulcerans_Agy99 -AVIAGFVARRLSVKPTDLVPQTVAWTMLGVALSAYEHWLSDESVSLPEA
MAV_4481|M.avium_104 -EVIAGFVARRCECKTTDLAPQTVAWMMLGVALSAYEHWLGDESVPLPVA
MSMEG_1420|M.smegmatis_MC2_155 -TVIAEYVADRLGMSTTDLMPQTVAWLMLGVALSAYENWLADESVSLRGA
MAB_3837|M.abscessus_ATCC_1997 -DVIAQFVARRSGTDPGSLLPQTVAWTLLGVALAAYEQWLADESSKLTTL
MLBr_01070|M.leprae_Br4923 YNTAAIQAERKCGVAPDTIPAEDLAVALQLMTERVMAATFSDEK-PLIPD
. * . : : .: :* : :: . : **. *
Mflv_5062|M.gilvum_PYR-GCK LGEAFDLLASGLSGLESGVSEFAPGARR
Mvan_1294|M.vanbaalenii_PYR-1 LGDAFDMLASGLAGLETGVSEFGA----
TH_1899|M.thermoresistible__bu LADAFDAIRPGLDALDG--KKFA-----
Mb0710c|M.bovis_AF2122/97 LGAAFDVVGAGLDRLNQ-----------
Rv0691c|M.tuberculosis_H37Rv LGAAFDVVGAGLDRLNQ-----------
MMAR_1019|M.marinum_M LGNAFDVVGAGLEKLD------------
MUL_0771|M.ulcerans_Agy99 LGNAFDVVGAGLEKLD------------
MAV_4481|M.avium_104 LGNAFDVVGAGLNGLDR-----------
MSMEG_1420|M.smegmatis_MC2_155 IAAAFEVARPGLDALQPAH---------
MAB_3837|M.abscessus_ATCC_1997 LGKGFDAAEVGLRALR------------
MLBr_01070|M.leprae_Br4923 KKVIDTLVHIWLASIYGS----------
* :