For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. vanbaalenii PYR-1 Mvan_2270 (-)

annotation: TetR family transcriptional regulator
coordinates: 2421905 - 2422507
length: 200

MDVVSGVDSGESLTVRKQRATKARIAAAAAQSVIDHGLAAATVERIAAAAEVGRATFFRYFSAKEDAVAE
GMTAHWLDLITAAIAAQPPHLPAGAALAAAFEDLGDGFDAISGQVRELATLTRSSPVFSAWTLQIYLRYE
SAIAELLGPRCPDPAPDDPRPRLLGALAMASVRIALDDWLVHGGSLPDRVRAALASIEVV
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_2270--100% (200)TetR family transcriptional regulator
M. vanbaalenii PYR-1Mvan_1927-2e-1228.43% (197) TetR family transcriptional regulator
M. vanbaalenii PYR-1Mvan_1156-1e-1031.53% (203) TetR family transcriptional regulator

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0790c-1e-0530.34% (89) hypothetical protein Mb0790c
M. gilvum PYR-GCKMflv_4072-4e-8780.40% (199) TetR family transcriptional regulator
M. tuberculosis H37RvRv0767c-1e-0530.34% (89) hypothetical protein Rv0767c
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3705-3e-0736.47% (85) TetR family regulatory protein
M. marinum MMMAR_0222-2e-6567.55% (188) TetR family transcriptional regulator
M. avium 104MAV_2657-3e-1230.46% (174) transcriptional regulator
M. smegmatis MC2 155MSMEG_5673-6e-1043.04% (79) transcriptional regulator
M. thermoresistible (build 8)TH_3524-2e-0830.59% (170) PUTATIVE -
M. ulcerans Agy99MUL_4892-4e-6465.96% (188) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mvan_2270|M.vanbaalenii_PYR-1       ----------MDVVSGVDSGESLTVRKQRATKARIAAAAAQSVIDHGLAA
Mflv_4072|M.gilvum_PYR-GCK          ----MRHSLIMDAVSGPKSGESLTVRRQRATKARIAAAAAEAVAAHGLAG
MMAR_0222|M.marinum_M               -------------MSPPPAATSLAERKRTATRQRIATAAAQLVADLGLAA
MUL_4892|M.ulcerans_Agy99           -------------MSPPPAATALAERKRTATRQRIATAAAQLVADLGLVA
Mb0790c|M.bovis_AF2122/97           MSSDVLVTTPAQRQTEPHAEAVSRNRRQQATFRKVLAAAMATLREKSYAD
Rv0767c|M.tuberculosis_H37Rv        MSSDVLVTTPAQRQTEPHAEAVSRNRRQQATFRKVLAAAMATLREKSYAD
MAV_2657|M.avium_104                ---------------MARGDRSPRDAHADRVRNALLNAALNLFSTNGYDE
MSMEG_5673|M.smegmatis_MC2_155      -------------MAYQTQQPGLRERKKQRTRATLISAAIDLCVRQGYEQ
TH_3524|M.thermoresistible__bu      -------------------------VRGHRNREALIAAAIDLFTVNGYEQ
MAB_3705|M.abscessus_ATCC_1997      -----------------------MPPDASATKKRLLDAAYAEFAEHGLAG
                                                                      :  **       .   

Mvan_2270|M.vanbaalenii_PYR-1       ATVERIAAAAEVGRATFFRYFSAKEDAVAEGMTAHWLDLITAAIAAQPPH
Mflv_4072|M.gilvum_PYR-GCK          ATIEHIAAAAEVGRATFFRYFSAKEDAVVEGMAAHWLDAIADAIAAQPPE
MMAR_0222|M.marinum_M               ATVERIADTADISRATFFRYFNSKEDAVAEGMTAHWLDRIATALAAQPEH
MUL_4892|M.ulcerans_Agy99           ATVERIADTADISRATFFRYFNSKEDAVAEGMTAHWLDRIATALAAQPEH
Mb0790c|M.bovis_AF2122/97           LTVRLVAARAKVAPATAYTYFSSKNHLIAE-VYLDLVRQVPCVTDVNVPM
Rv0767c|M.tuberculosis_H37Rv        LTVRLVAARAKVAPATAYTYFSSKNHLIAE-VYLDLVRQVPCVTDVNVPM
MAV_2657|M.avium_104                TTTDQIAESVGVSPRTFFRYFPTK-ESVLFFGEYDFIDAVSGVYLAQPEE
MSMEG_5673|M.smegmatis_MC2_155      TTVEQIAAAAEVSARTFSRYFATK-DAVMLAFLDDVVDLVAGELAQQPPE
TH_3524|M.thermoresistible__bu      TTVEQIAEAAGVAPRTFFRHFAAKEDILFHGYADRLAEATRRFRAARSGS
MAB_3705|M.abscessus_ATCC_1997      ARVDRIGAAAEANKRLLYVYYTNK-ETLFDIVVAHSIQQMSEAVPFTPED
                                         :.  .         ::  * . :                      

Mvan_2270|M.vanbaalenii_PYR-1       LPAGAALAA----AFEDLGDGFD--AISGQVRELATLTRSSPVFSAWTLQ
Mflv_4072|M.gilvum_PYR-GCK          LAADAAVVA----AFQDLGHGFE--AVSDQVRELAVMTRSSPVFSAWTLQ
MMAR_0222|M.marinum_M               LSAVEAVVG----AFGGLAVGFA--EMEDQVRELATLTRSSETLEAWTLH
MUL_4892|M.ulcerans_Agy99           QSAVEAVVG----AFGGLAVGFA--EMEDQVRELATLTRSSETLEAWTLH
Mb0790c|M.bovis_AF2122/97           PIRVTSSLR----HLALVVADEP--EIGAACTAALLDGGADPAVRAVRDR
Rv0767c|M.tuberculosis_H37Rv        PIRVTSSLR----HLALVVADEP--EIGAACTAALLDGGADPAVRAVRDR
MAV_2657|M.avium_104                ASDFEALAN----SFALLAPGLK--RIRKRIAQYHDAVASSLVLLGRERK
MSMEG_5673|M.smegmatis_MC2_155      LGELDAVFCAHITAFEKTRVAMPGQLTDDRLLAAARIFTSSPSLMQATMG
TH_3524|M.thermoresistible__bu      LWKALAEAS------EAVATAIA--ENPGIFLVRARMYGELPALRATMLR
MAB_3705|M.abscessus_ATCC_1997      LPGYAGALFD---HLIKHPEHLR----LATWAQLERPAAGPAETSAYAAK
                                         .                                            

Mvan_2270|M.vanbaalenii_PYR-1       I-YLRYESAIAELLGPRCPDPAPDDPRPRLLGALAMA-SVRIALDDWLVH
Mflv_4072|M.gilvum_PYR-GCK          L-YLRYEAAIADLVGIRMADPAPDDPRPRLLGALAMA-SVRIALDDWLVH
MMAR_0222|M.marinum_M               I-YVRYESAIADLIAPRIPNLVPQDPRPRLVGALAMA-VVRIALDDWLGQ
MUL_4892|M.ulcerans_Agy99           I-YVRYESAIADLIAPRIPNLVPQDPRPRLVGALAMA-VVRIALDDWLGQ
Mb0790c|M.bovis_AF2122/97           I-GAEIHRRITSAIGPGADPGTVFALEMAFFGALVQAGSGTFTYHEIADR
Rv0767c|M.tuberculosis_H37Rv        I-GAEIHRRITSAIGPGADPGTVFALEMAFFGALVQAGSGTFTYHEIADR
MAV_2657|M.avium_104                N-HEANAETVAQVIAERRRMPAP-DSECRLLAAVGML-LVERALNQWLST
MSMEG_5673|M.smegmatis_MC2_155      FRPAPLFEVLAKRMGVSADDRKIALIASLWNAIMTTALVQLVPDVDWATV
TH_3524|M.thermoresistible__bu      I-NDDWIDQMTTEVARWLGSDAAVDVRPRLAATVING-ANRTAIDLWVSA
MAB_3705|M.abscessus_ATCC_1997      VAAIAQTGLSAGDVEPADILALTLGLTTAWLGASPALRGLAASEPFSPER
                                              :  :                 .          .       

Mvan_2270|M.vanbaalenii_PYR-1       GG------SLPDRVRAALASIEVV-----------------
Mflv_4072|M.gilvum_PYR-GCK          GG------SLPERVRTALASLHVA-----------------
MMAR_0222|M.marinum_M               GG------SLPDRVQQGLAAIVIA-----------------
MUL_4892|M.ulcerans_Agy99           GG------SLPDRVQQGLAAIVIA-----------------
Mb0790c|M.bovis_AF2122/97           LG------YVVGLILAGANEPSTGGSE--------------
Rv0767c|M.tuberculosis_H37Rv        LG------YVVGLILAGANEPSTGGSE--------------
MAV_2657|M.avium_104                PGR-----SLDDLIRQEFAALPAVLK---------------
MSMEG_5673|M.smegmatis_MC2_155      TVE-----RIVNQMRTTYAEFLEVAGRRHEFA---------
TH_3524|M.thermoresistible__bu      DGKGDLVELMADAVRLVRPTLDRIERESRTVANPVRRRDVV
MAB_3705|M.abscessus_ATCC_1997      LAT-----HRTALIAAVEALVSAAAR---------------
                                                 :