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ANPVGLRERRRRQTSADIRDAAVRLTLERGFDKVTVDEICAEAGISTRTFFNYFPNKESAIAYGPSDIPP ELVADFVAAGPAPYSVVLAELIALAAHHLRDVPPRREHAANMLELAKTSPAVLAAFLADLERFQNQLTDI IVRRQGMQPDDEMAPLISALALTAVRSGIEKWASGEASETDDTPMPYVERAAALVNSIFTK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2512 | - | - | 100% (202) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_0350 | - | 3e-15 | 32.16% (171) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_1952 | - | 1e-13 | 28.05% (164) | transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0710c | - | 2e-08 | 26.63% (169) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_4072 | - | 4e-13 | 28.82% (170) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0691c | - | 2e-08 | 26.63% (169) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_00717 | - | 7e-07 | 26.99% (163) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3837 | - | 4e-10 | 26.01% (173) | transcriptional regulatory protein TetR |
| M. marinum M | MMAR_3861 | - | 9e-14 | 29.74% (195) | putative regulatory protein |
| M. smegmatis MC2 155 | MSMEG_5673 | - | 5e-12 | 29.01% (162) | transcriptional regulator |
| M. thermoresistible (build 8) | TH_1899 | - | 2e-10 | 28.48% (158) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. ulcerans Agy99 | MUL_2714 | - | 1e-13 | 31.28% (195) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_2270 | - | 5e-12 | 29.17% (168) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0710c|M.bovis_AF2122/97 -------------MPHESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVD
Rv0691c|M.tuberculosis_H37Rv -------------MPHESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVD
TH_1899|M.thermoresistible__bu ---------------------------------VALDLFADRGFDEVSVD
MAB_3837|M.abscessus_ATCC_1997 ------------MNAQPARVGRRPSTTRDEITAVAMTLFAQHGFDEVSVD
Mflv_4072|M.gilvum_PYR-GCK MRHSLIMDAVSGPKSGESLTVRRQRATKARIAAAAAEAVAAHGLAGATIE
Mvan_2270|M.vanbaalenii_PYR-1 ------MDVVSGVDSGESLTVRKQRATKARIAAAAAQSVIDHGLAAATVE
MAV_2512|M.avium_104 ------------MANPVGLRERRRRQTSADIRDAAVRLTLERGFDKVTVD
MMAR_3861|M.marinum_M ---MASEGDGMNPANIGSLRDRRRAELFSLIQQTAHRLFAERGFDAVTTE
MUL_2714|M.ulcerans_Agy99 ---------MPDDHPPTGLRQRKKADTRRALSDAALALAFERGLDNVTRE
MSMEG_5673|M.smegmatis_MC2_155 ---------MAYQTQQPGLRERKKQRTRATLISAAIDLCVRQGYEQTTVE
MLBr_00717|M.leprae_Br4923 --------------MTTARRRLSPEDRRAELLALGAEVFGKRPYDEVRID
. : . :
Mb0710c|M.bovis_AF2122/97 DIARAAGIARRTLFRYYASKN-AIPWGDFSTHLAQLQGLLDNIDSR----
Rv0691c|M.tuberculosis_H37Rv DIARAAGIARRTLFRYYASKN-AIPWGDFSTHLAQLQGLLDNIDSR----
TH_1899|M.thermoresistible__bu DVAAAAGIGRRTLFRYYPSKN-AIPWGDFDAHLDRMRDLLDGIGPD----
MAB_3837|M.abscessus_ATCC_1997 DIAAAAGIARRTVFRYYSSKN-AIVWGDFDSHLGVMRALLDETADT----
Mflv_4072|M.gilvum_PYR-GCK HIAAAAEVGRATFFRYFSAKEDAVVEGMAAHWLDAIADAIAAQPPE----
Mvan_2270|M.vanbaalenii_PYR-1 RIAAAAEVGRATFFRYFSAKEDAVAEGMTAHWLDLITAAIAAQPPH----
MAV_2512|M.avium_104 EICAEAGISTRTFFNYFPNKESAIAYGPSDIPPELVADFVAAGPAP----
MMAR_3861|M.marinum_M DIAAAAGVSISTYFRHAPTKE-GLLVDPVRQAITEIVSSYRSWPAD----
MUL_2714|M.ulcerans_Agy99 DIANVAGVSLRTFNNYFTGKYEALAYRQTERMRRSIAALRERPAGEPLWT
MSMEG_5673|M.smegmatis_MC2_155 QIAAAAEVSARTFSRYFATKD-AVMLAFLDDVVDLVAGELAQQPPE---L
MLBr_00717|M.leprae_Br4923 EIAERAGVSRALMYHYFPDKR-AFFAAVVKDEADRLYAATNIPPPAG---
:. * :. .: . * .. :
Mb0710c|M.bovis_AF2122/97 IQLRDALRAALLAFNTFDES-ETIRHRKRMRVILQTPELQ-------AYS
Rv0691c|M.tuberculosis_H37Rv IQLRDALRAALLAFNTFDES-ETIRHRKRMRVILQTPELQ-------AYS
TH_1899|M.thermoresistible__bu VPIGAALRSMLLAFNDFGED-ETGRHRRRMRVILQTDALQ-------AHS
MAB_3837|M.abscessus_ATCC_1997 VDTSTALRQAVLTFNDFPVD-ETPRHRMRMRMILEVPALQ-------AYS
Mflv_4072|M.gilvum_PYR-GCK LAADAAVVAAFQDLGHGFEA-VSDQVRELAVMTRSSPVFS-------AWT
Mvan_2270|M.vanbaalenii_PYR-1 LPAGAALAAAFEDLGDGFDA-ISGQVRELATLTRSSPVFS-------AWT
MAV_2512|M.avium_104 YSVVLAELIALAAHHLRDVPPRREHAANMLELAKTSPAVL-------AAF
MMAR_3861|M.marinum_M ESAVEALIALFVSYARDAGD---LKLDTWRRAIATAPYLL-------SKS
MUL_2714|M.ulcerans_Agy99 AIAHAVLEPLQADLHEATADEDRLPSRGELAEVRKLLMNP-------QIR
MSMEG_5673|M.smegmatis_MC2_155 GELDAVFCAHITAFEKTRVAMPGQLTDDRLLAAARIFTSS-------PSL
MLBr_00717|M.leprae_Br4923 LTMFEEVRVGVLAYMAYHKQNPEAAWAAYVGLGRSDPVLLGIDDEAKNRQ
Mb0710c|M.bovis_AF2122/97 MTMYAGWR-EVIAKFVARRSGG-KTTDFMPQTVAWTMLGVALSAYEHWLR
Rv0691c|M.tuberculosis_H37Rv MTMYAGWR-EVIAKFVARRSGG-KTTDFMPQTVAWTMLGVALSAYEHWLR
TH_1899|M.thermoresistible__bu MTMYAGWR-AVVADFVARRLGL-APSDLVPQTVAWTMLGVALSAYAYWLA
MAB_3837|M.abscessus_ATCC_1997 MLMYTGWR-DVIAQFVARRSGT-DPGSLLPQTVAWTLLGVALAAYEQWLA
Mflv_4072|M.gilvum_PYR-GCK LQLYLRYE-AAIADLVGIRMADPAPDDPRPRLLGALAMASVRIALDDWLV
Mvan_2270|M.vanbaalenii_PYR-1 LQIYLRYE-SAIAELLGPRCPDPAPDDPRPRLLGALAMASVRIALDDWLV
MAV_2512|M.avium_104 LADLERFQ-NQLTDIIVRRQGM-QPDDEMAPLISALALTAVRSGIEKWAS
MMAR_3861|M.marinum_M ALVSEDDQ-HRFIEHVASRMGVDARTDIRPALLVHTSLATVKFVFDRWLS
MUL_2714|M.ulcerans_Agy99 EAASRELL-EDWRDAIAERTGTDPENDMYPRLVVAVVRAVGDAAMDTYAT
MSMEG_5673|M.smegmatis_MC2_155 MQATMGFRPAPLFEVLAKRMGVSADDRKIALIASLWNAIMTTALVQLVPD
MLBr_00717|M.leprae_Br4923 MEHIMSRIGDVVSVVPESKLHPDIERDLRVIVHGWLAFTFEVCRQRIMDP
:
Mb0710c|M.bovis_AF2122/97 -DESVSLTEALGAAFDVVGAGLDRLNQ--------------
Rv0691c|M.tuberculosis_H37Rv -DESVSLTEALGAAFDVVGAGLDRLNQ--------------
TH_1899|M.thermoresistible__bu -DESVPLAQALADAFDAIRPGLDALDGKKFA----------
MAB_3837|M.abscessus_ATCC_1997 -DESSKLTTLLGKGFDAAEVGLRALR---------------
Mflv_4072|M.gilvum_PYR-GCK -HGG-SLPERVRTALASLHVA--------------------
Mvan_2270|M.vanbaalenii_PYR-1 -HGG-SLPDRVRAALASIEVV--------------------
MAV_2512|M.avium_104 -GEASETDDTPMPYVERAAALVNSIFTK-------------
MMAR_3861|M.marinum_M -TDPPSSPIFHVQMDQALRIALAGFR---------------
MUL_2714|M.ulcerans_Agy99 ADPPVAITELIRAGFASVAAGLPEPAKPGEQRG--------
MSMEG_5673|M.smegmatis_MC2_155 VDWATVTVERIVNQMRTTYAEFLEVAGRRHEFA--------
MLBr_00717|M.leprae_Br4923 STDADRLADSCAHALLDAIARVPEISKELADAMAIARQPPQ