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DLSQRLKDKVAVITGGASGIGLATAKRMRSEGAIVVIGDLDEKTGKSVANDLNVTFVQVDVSDQVAVDNL FDTAFEVHGGVDIAFNNAGISPPEDDLIENTGIDAWDRVQDINLKSVFFCCKAALRHMVPAQKGSIVNTA SFVAVNGSATSQISYTASKGGVLAMSRELGIQYARQGIRVNALCPGPVNTPLLQELFAKDPERAARRLVH VPMGRFAEPEELAAAVAFLASDDASFITGSSFLVDGGITGHYVTPL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4062 | - | - | 100% (257) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_2001 | - | 6e-40 | 37.60% (250) | short-chain dehydrogenase/reductase SDR |
| M. gilvum PYR-GCK | Mflv_4508 | - | 2e-37 | 38.17% (262) | short-chain dehydrogenase/reductase SDR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2882c | - | 1e-110 | 76.65% (257) | short chain dehydrogenase |
| M. tuberculosis H37Rv | Rv2857c | - | 1e-110 | 76.65% (257) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 3e-30 | 35.27% (241) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_4680c | - | 8e-31 | 34.94% (249) | putative short-chain dehydrogenase/reductase |
| M. marinum M | MMAR_2981 | fabG3_1 | 2e-37 | 36.29% (248) | 20-beta-hydroxysteroid dehydrogenase FabG3_1 |
| M. avium 104 | MAV_3714 | - | 1e-106 | 73.15% (257) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_2598 | - | 1e-118 | 82.49% (257) | short chain dehydrogenase |
| M. thermoresistible (build 8) | TH_4254 | - | 6e-39 | 36.51% (252) | PUTATIVE putative 2,5-dichloro-2,5-cyclohexadiene-1,4-diol |
| M. ulcerans Agy99 | MUL_4844 | - | 4e-36 | 33.85% (260) | short-chain type dehydrogenase/reductase |
| M. vanbaalenii PYR-1 | Mvan_2281 | - | 1e-137 | 93.77% (257) | short chain dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4062|M.gilvum_PYR-GCK ------------MDLSQRLKDKVAVITGGASGIGLATAKRMRSEGAIVVI
Mvan_2281|M.vanbaalenii_PYR-1 ------------MDLGQRLKDKVAVITGGASGIGLATAKRMQAEGAIVVI
Mb2882c|M.bovis_AF2122/97 -----------MMDLSQRLAGRVAVITGGGSGIGLAAGRRMRAEGATIVV
Rv2857c|M.tuberculosis_H37Rv -----------MMDLSQRLAGRVAVITGGGSGIGLAAGRRMRAEGATIVV
MAV_3714|M.avium_104 -----------MMDLTQRLAGRVAVITGAGGGIGLAAARRMHAEGATIVV
MSMEG_2598|M.smegmatis_MC2_155 ------------MDLTQRLAGKVAVITGGASGIGLATGRRLRAEGATVVV
MAB_4680c|M.abscessus_ATCC_199 -----------MNGNSALLQGKNVIVTGGARGLGAAFSRHIVSQGGRVVI
MMAR_2981|M.marinum_M -----------MAGR---LTGKVALVSGGARGMGASHVRALVAEGAHVVL
TH_4254|M.thermoresistible__bu -----------MTAGSTRLAGKVVLVTGAGGGLGTAIARRLADEGARLVL
MUL_4844|M.ulcerans_Agy99 --------------MTAELENKVAIITGACGGIGLETSRVPACAGARVVL
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
: .: :::*. *:* : * :.:
Mflv_4062|M.gilvum_PYR-GCK GDLDEKTGKSVANDLNVTFVQVD-----VSDQVAVDNLFDTAFEVHGGVD
Mvan_2281|M.vanbaalenii_PYR-1 GDVDASTGKSVANDMNVTFVQVD-----VADQVAVDHLFDTAFEVHGGVD
Mb2882c|M.bovis_AF2122/97 GDVDVEAGGAAADELSGLFVPTD-----VCDEDAVNGLFDGAAETYGRID
Rv2857c|M.tuberculosis_H37Rv GDVDVEAGGAAADELSGLFVPTD-----VCDEDAVNGLFDGAAETYGRID
MAV_3714|M.avium_104 ADIDADAGAAAADELSGLFVPTD-----VADEDAVNALFDTAVRRYGRID
MSMEG_2598|M.smegmatis_MC2_155 GDIDPTTGKAAADELEGLFVPVD-----VSEQEAVDNLFDTAASTFGRVD
MAB_4680c|M.abscessus_ATCC_199 ADVLDGDGRQLAAELGDAARFTH---LDVTDAEQWRELIDTTLAGFGTIT
MMAR_2981|M.marinum_M GDILDDEGRAVAAELGDAARYVH---LDVTQPEQWTAAVDTAVNEFGGLH
TH_4254|M.thermoresistible__bu ADLQESQCAALADELPAPAGAHHPLGFDVADETAWISAISTVSAQYGALH
MUL_4844|M.ulcerans_Agy99 ADLPETDLAGAAASVGRGAVHHV---VDLTNEVSVRALIDFTIDTFGRLD
MLBr_01807|M.leprae_Br4923 THR--------ASVVPDWFFGVEC---DVTDNDAIGAAFKAVEEHQGPVE
. * : : : .. . * :
Mflv_4062|M.gilvum_PYR-GCK IAFNNAGISPPEDDLIENTGIDAWDRVQDINLKSVFFCCKAALRHMVPAQ
Mvan_2281|M.vanbaalenii_PYR-1 IAFNNAGISPPEDDLIENTGVDAWDRVQDINLKSVFFCCKAALRHMVPAQ
Mb2882c|M.bovis_AF2122/97 IAFNNAGISPPEDNLIENTELAAWQRVQDVNLKSVYLCCRAALRHMVLAG
Rv2857c|M.tuberculosis_H37Rv IAFNNAGISPPEDNLIENTELAAWQRVQDVNLKSVYLCCRAALRHMVLAG
MAV_3714|M.avium_104 IAFNNAGISPPDDDVIENTEPPAWQRVQDVNLKSVYLCCRAALRHMVSAR
MSMEG_2598|M.smegmatis_MC2_155 IAFNNAGISPPEDDLIENTDLPAWQRVQDINLKSVYLSCRAALRHMVPAG
MAB_4680c|M.abscessus_ATCC_199 GLVNNAGISSAA--MVADEPLEHFRKVIEINLVGVFIGMQAVIPAMRAHG
MMAR_2981|M.marinum_M VLVNNAGILNIG--TIEDYALSEWQRILDINVTGVFLGIRAAVKPMKEAG
TH_4254|M.thermoresistible__bu ALVNNAAIGALG--NVAEERLERWDRILDVGATGVWLGMKHAVPLIRRSG
MUL_4844|M.ulcerans_Agy99 IVDNNAAHSDPADMLVSQMTVDVWDDTFTVNARGTMLMCKYAIPRLISAG
MLBr_01807|M.leprae_Br4923 VLVANAGITSDM--LIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQR
**. : : :. .. : . :
Mflv_4062|M.gilvum_PYR-GCK KGSIVNTASFVAVNGSATSQISYTASKGGVLAMSRELGIQYARQGIRVNA
Mvan_2281|M.vanbaalenii_PYR-1 KGSIINTASFVAVMGSATSQISYTASKGGVLAMSRELGVQYARQGIRVNA
Mb2882c|M.bovis_AF2122/97 KGSIVNTASFVAVMGSATSQISYTASKGGVLAMSRELGVQFARQGIRVNA
Rv2857c|M.tuberculosis_H37Rv KGSIVNTASFVAVMGSATSQISYTASKGGVLAMSRELGVQFARQGIRVNA
MAV_3714|M.avium_104 RGSIINTASFVAVMGSATSQISYTAAKGGVLALSRELGVQFARQGIRVNA
MSMEG_2598|M.smegmatis_MC2_155 KGSIINTASFVAVMGSATSQISYTASKGGVLAMSRELGVQYARQGIRVNA
MAB_4680c|M.abscessus_ATCC_199 CGSIVNISSAAGLVG-LALTSGYGASKWGVRGLSKVAAIELGRERIRVNS
MMAR_2981|M.marinum_M RGSIINISSIEGLAG-TIASHGYTVSKFAVRGLTKSTALELGPSGIRVNS
TH_4254|M.thermoresistible__bu GGSVVNICSIFGTVGGFGDSAAYHAAKGAVRTLTKNAALHWAPDGVRVNS
MUL_4844|M.ulcerans_Agy99 GGAIVNISSATAHAA-YDMSTAYSCTKAAIETLTRYVATQYGRHGVRCNA
MLBr_01807|M.leprae_Br4923 FGRYIFMGSVVGLSG-VPGQANYAASKSGLIGMARSLARELGSRSITANV
* : * . . * :* .: ::: . . . : *
Mflv_4062|M.gilvum_PYR-GCK LCPGPVNTPLLQELFAKDPERAARRLVHVPMGRFAEPEELAAAVAFLASD
Mvan_2281|M.vanbaalenii_PYR-1 LCPGPVNTPLLQELFAKDPERAARRLVHVPVGRFAEPEELAAAVAFLASD
Mb2882c|M.bovis_AF2122/97 LCPGPVNTPLLQELFAKNPERAARRMVHVPLGRFAEPDEIAAAVAFLASD
Rv2857c|M.tuberculosis_H37Rv LCPGPVNTPLLQELFAKNPERAARRMVHVPLGRFAEPDEIAAAVAFLASD
MAV_3714|M.avium_104 LCPGPVNTPLLQELFAKDPQRAARRLVHVPVGRFAEPGEIAAAAAFLASD
MSMEG_2598|M.smegmatis_MC2_155 LCPGPVNTPLLQELFAKDPERAARRLVHIPLGRFAEPEELAAAVAFLASD
MAB_4680c|M.abscessus_ATCC_199 VHPGVIYTPMT--AKEGFR-EGEGNMPIAAMGRVGNADEVAGAVAYLLSD
MMAR_2981|M.marinum_M IHPGLVKTPMT--EWV------PEDLFQTALGRAAEPMEVSNLVVYLASD
TH_4254|M.thermoresistible__bu LHPGFIETPQLRELYKGTE-RYERMLAGTPLGRLGRPDEIAAVVAFLVSD
MUL_4844|M.ulcerans_Agy99 IAPGLVRTPRL-EVGLPQP-IVDIFATHHLAGLIGEPHEIAELVCFLASD
MLBr_01807|M.leprae_Br4923 VAPGFIDTEMTRAMDSKYQ---EAALQAIPLGRIGAVEEIAGAVSFLASE
: ** : * * . *:: . :* *:
Mflv_4062|M.gilvum_PYR-GCK DASFITGSSFLVDGGITGHYVTPL--------------
Mvan_2281|M.vanbaalenii_PYR-1 DASFITASSFLVDGGISGHYVTPL--------------
Mb2882c|M.bovis_AF2122/97 DASFITASTFLVDGGISSAYVTPL--------------
Rv2857c|M.tuberculosis_H37Rv DASFITASTFLVDGGISSAYVTPL--------------
MAV_3714|M.avium_104 DASFITASTFLVDGGISAAYVTPL--------------
MSMEG_2598|M.smegmatis_MC2_155 DASFITGSTFLVDGGISSAYVTPL--------------
MAB_4680c|M.abscessus_ATCC_199 AASYVTGAELAVDGGWTAGPTLTTITGQ----------
MMAR_2981|M.marinum_M ESSYSTGAEFVVDGGTVAGLAHKDFSAVDVAAQPEWVT
TH_4254|M.thermoresistible__bu DASFITGSEVYADGGWTAR-------------------
MUL_4844|M.ulcerans_Agy99 RAAFITGQVIAADSGLLAHLPGLPQIRASVAELQSQPS
MLBr_01807|M.leprae_Br4923 DAGYISGAVIPVDGGLGMGH------------------
:.: :. . .*.*