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VTAGWTTSAVSFPCDGEQIAGVLYRPEGGAPPFPCVVFAHGFSGTMDWILPDFAAVFCAAGLAVLTFDYR GFGSSEGTPRQIVNSARQLEDIRAALDVVRNRADVDPGRIGLWGTSLGGSHVLQIAAEDPRVAAVVANVP ALDMYTGLRGRHRSPDYRPGPAQIVVAVARLLSAAVVDEVRGRLGRSPRYLPVYGRLGRAFFADPALAQR FRAVEAQAPSWRNAVAPRFLLHAPRYRDGTIERVRCPVLVTLARDDAEVSTPFVERKVRRGRDVEIRKYP AGHFDMYHGAVRDEVARDQREFLIRHLQPDRAARKDR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3465 | - | - | 100% (317) | peptidase S15 |
| M. gilvum PYR-GCK | Mflv_3976 | - | 2e-48 | 39.47% (304) | dienelactone hydrolase |
| M. gilvum PYR-GCK | Mflv_4372 | - | 3e-36 | 34.55% (301) | alpha/beta hydrolase fold |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2330c | - | 3e-11 | 33.61% (122) | hypothetical protein Mb2330c |
| M. tuberculosis H37Rv | Rv2307c | - | 3e-11 | 33.61% (122) | hypothetical protein Rv2307c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2608 | - | 7e-39 | 36.09% (302) | putative hydrolase, alpha/beta fold |
| M. marinum M | MMAR_0385 | - | 3e-43 | 36.18% (304) | hypothetical protein MMAR_0385 |
| M. avium 104 | MAV_2688 | - | 6e-06 | 34.38% (64) | alpha/beta hydrolase |
| M. smegmatis MC2 155 | MSMEG_4450 | - | 1e-36 | 34.47% (322) | alpha/beta hydrolase |
| M. thermoresistible (build 8) | TH_2570 | - | 3e-52 | 40.61% (293) | PUTATIVE alpha/beta hydrolase fold |
| M. ulcerans Agy99 | MUL_1035 | - | 2e-42 | 36.04% (308) | hypothetical protein MUL_1035 |
| M. vanbaalenii PYR-1 | Mvan_1417 | - | 1e-120 | 67.20% (311) | peptidase S15 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3465|M.gilvum_PYR-GCK --MTAGWTTSAVSFPCDGEQIAGVLYRPEGGAPP--FPCVVFAHGFSGTM
Mvan_1417|M.vanbaalenii_PYR-1 --MGVGFTTRQVSFSSGGSRIAAELYLPAG-PGP--YPAVVFAHGFSGTM
MMAR_0385|M.marinum_M -----MTQRQDVRFPCGEAMISAWLYRPAGADPARPVPMLVMAHGLGAVR
MUL_1035|M.ulcerans_Agy99 -----MTQRQDVRFPCGEALISAWLYRPAGADPARPVPMLVMAHGLGAVR
MAV_2688|M.avium_104 --------------------------------------------------
MAB_2608|M.abscessus_ATCC_1997 ------MNRQSIRFNSHGIDCEAWLYRAQTVEDT--APIVVMAHGVGGTK
MSMEG_4450|M.smegmatis_MC2_155 MAQPLSYTRDDVTFMSDGTSCAAWLYRPDGVNNP---PIVVLAHGFAAFR
TH_2570|M.thermoresistible__bu ---MATTDRRDLRIPAHGEQLAAYFYPPAGAGPT--TPCIVMAHGFTATR
Mb2330c|M.bovis_AF2122/97 ---MSLKRCRALPVVAIVALVASGVITFIWSQQR--RLIYFPSAGPVPSA
Rv2307c|M.tuberculosis_H37Rv ---MSLKRCRALPVVAIVALVASGVIMFIWSQQR--RLIYFPSAGPVPSA
Mflv_3465|M.gilvum_PYR-GCK DWILPDFAAVFCAAGLAVLTFDYRGFGSSEGTPRQIVNSARQLEDIRAAL
Mvan_1417|M.vanbaalenii_PYR-1 DWILPDFASVFAAGGLAVLLFDYRHFGSSEGQPRQLVDTGCQLEDIRAAL
MMAR_0385|M.marinum_M TMRLDAYAQRFSAAGYACLVFDYRNFGDSEGQPRQLLDIRMQLQDWAAAV
MUL_1035|M.ulcerans_Agy99 TMRLDAYAQRFSAAGYACLVFDYRNFGDSEGQPRQLLDIRMQLQDWAAAV
MAV_2688|M.avium_104 --------------------------------------------------
MAB_2608|M.abscessus_ATCC_1997 DSGLEPFAVRLAEAGMHALAFDYRGFGASDGFPRQHVSFTHQIGDYHAAV
MSMEG_4450|M.smegmatis_MC2_155 ELRLDAYAARFAQAGYAALVFDYRHWGASDGQPRRILDIPKQQTDWRAAI
TH_2570|M.thermoresistible__bu DDGLPAYAEAFHAAGYAVVLFDYRHFGASTGEPRQLLDITRQHDDYRAVV
Mb2330c|M.bovis_AF2122/97 SSVLPAGRDVVVETQDGMRLGGWYFPHTSGGSGPAVLVCNGNAGDRSMRA
Rv2307c|M.tuberculosis_H37Rv SSVLPAGRDVVVETQDGMRLGGWYFPHTSGGSGPAVLVCNGNAGDRSMRA
Mflv_3465|M.gilvum_PYR-GCK DVVRNRADVDPGRIGLWGTSLGGSHVLQIAAEDPRVAAVVANVPALDMYT
Mvan_1417|M.vanbaalenii_PYR-1 AYARAHEAIDARRIGLWGTSLGGSHVINVASADPRIAAVVATVPALDMYV
MMAR_0385|M.marinum_M AYARTCDGVDQARIGLWGTSFGGGHVIATAARLPGIAAVVAQCPFTDGIA
MUL_1035|M.ulcerans_Agy99 AYARTCDGVDQARIGLWGTSFGGGHVIATAARLPGIAAVVAQCPFTDGIA
MAV_2688|M.avium_104 --------------------------------------------------
MAB_2608|M.abscessus_ATCC_1997 NMARRLPGVDPTRIVLWGVSLAGGHVMAVAGARNDVAAVIALTPLVDGIA
MSMEG_4450|M.smegmatis_MC2_155 AYARSLDNVDTTRLVGWGSSFGGGHVLTLAARDHEFAAAIVQVPHVSGPA
TH_2570|M.thermoresistible__bu AWARTQPGVDPDRIVLWGSSFSGGHVLVVAADDPRIAAVISQAPFTDAVP
Mb2330c|M.bovis_AF2122/97 ELAVALHGLGLSVLLFDYRGYGG------NPGRPSEQGLAADARAAQEWL
Rv2307c|M.tuberculosis_H37Rv ELAVALHGLGLSVLLFDYRGYGG------NPGRPSEQGLAADARAAQEWL
Mflv_3465|M.gilvum_PYR-GCK GLRGRHRSPDYRPGPAQIVVAVARLLSAAVVDEVRGRLGRSPRYLPVYGR
Mvan_1417|M.vanbaalenii_PYR-1 GLRGRHRPATFRPGPARTVIATLRLVGAAALDAIRGRCGLRPYYLPVYGP
MMAR_0385|M.marinum_M SVLAIAPT------------TAIRVTARSMRDLIGSRLGRPPVMIPTAGK
MUL_1035|M.ulcerans_Agy99 SVLAIAPT------------TAIRVTARSMRDLIGSRLGRPPVMIPTAGK
MAV_2688|M.avium_104 --------------------------------------------------
MAB_2608|M.abscessus_ATCC_1997 AARSAMTE------------HSAGTLLRSAVTGLRSRLGRQQRTIPIVGR
MSMEG_4450|M.smegmatis_MC2_155 SAFSQSPK------------LVARLIAAGLRDQIGAWFGGAPHRVTSIGR
TH_2570|M.thermoresistible__bu TLRKVPPA------------TIARLAVAGLRDQIGSWRGRPPRTASAVGA
Mb2330c|M.bovis_AF2122/97 SGQSDVDP------------ARIAYFGESLGAAVAVGLAVQRPPAALVLR
Rv2307c|M.tuberculosis_H37Rv SGQSDVDP------------ARIAYFGESLGAAVAVGLAVQRPPAALVLR
Mflv_3465|M.gilvum_PYR-GCK LG-RAFFADPALAQRFRAVEA--------QAPSWRNAVAPRFLLHAPRYR
Mvan_1417|M.vanbaalenii_PYR-1 LG-HAVFSDPALAERFRHVES--------NSPTWRNEVTPRFLFHAPRYR
MMAR_0385|M.marinum_M PGEVALMTAPDAYPGYLGLMP--------QGTQVPNEVAARIGIKVLGYR
MUL_1035|M.ulcerans_Agy99 PGEVALMTAPDAYPGYLGLMP--------QGTQVPNEVAARIGIKVLGYR
MAV_2688|M.avium_104 --------------------------------------------------
MAB_2608|M.abscessus_ATCC_1997 AGELAALTSDGYYEAHLAIAG--------P--AWRNEIDATVGTQLVSYR
MSMEG_4450|M.smegmatis_MC2_155 PGEFAMMTSPGAYELVEEMAGGEAAEHMRAQLEAENDVAARIALRVPLYS
TH_2570|M.thermoresistible__bu PGAVAAMTTPDAEPGFRAIVE--------PDSLWRNEFAARLMLRFPFYR
Mb2330c|M.bovis_AF2122/97 SPFTSLAEVGAVHYPWLPLRR----------------------LLLDHYP
Rv2307c|M.tuberculosis_H37Rv SPFTSLAEVGAVHYPWLPLRR----------------------LLLDHYP
Mflv_3465|M.gilvum_PYR-GCK DG-TIERVRCPVLVTLARDDAEVSTPFVERKVRRGRDV----EIRKYPAG
Mvan_1417|M.vanbaalenii_PYR-1 DG-TVERIRCPVLVTLARDDAEVSSPYVRRKLGHAADV----EIMEYPVA
MMAR_0385|M.marinum_M PGRSARKIACPILFCVCETDSVAPAGPTLRYAARAPRG----EVIRYPEG
MUL_1035|M.ulcerans_Agy99 PGRSARKIACPILFCVCETDSVAPAGPTLRYAARAPRGEVSGEVIRYPEG
MAV_2688|M.avium_104 -------MSCPILFAICENDTVAPAKATQKYAAQAPRG----EIKLYDAG
MAB_2608|M.abscessus_ATCC_1997 PTRCASRIGCPILVQIADFDRAAPPHAAAK-AAFKARA----EVRHYPCD
MSMEG_4450|M.smegmatis_MC2_155 PGRHAAKITAPTLVQLATKDDVTPYAKARKIVARIPNG----EVRSYDIT
TH_2570|M.thermoresistible__bu PVRVAGRINAPLLVCVCDDDAVTPPEPAIEAARRAPRG----QLRRYPYG
Mb2330c|M.bovis_AF2122/97 SIERIASVHAPVLVIAGGSDDIVPATLSEWLVAAAAEPKRYVVVPGVGHN
Rv2307c|M.tuberculosis_H37Rv SIERIASVHAPVLVIAGGSDDIVPATLSERLVAAAAEPKRYVVVPGVGHN
: .* *. * .. :
Mflv_3465|M.gilvum_PYR-GCK HFDMYHG-AVRDEVARDQREFLIRHLQ--PDRAARKDR---
Mvan_1417|M.vanbaalenii_PYR-1 HFDVYHG-PVRAEIARDQRDFLVRHLLRGPNRATNSSGCGR
MMAR_0385|M.marinum_M HFAIYLG-DAFERVVADQLGFLDKHLKPAGQP---------
MUL_1035|M.ulcerans_Agy99 HFAIYLG-DAFEHVVADQLGFLDKHLKPAGQP---------
MAV_2688|M.avium_104 HFDIYVG-ADFERNVTDQLNFLSRHVPVS------------
MAB_2608|M.abscessus_ATCC_1997 HFGVYHGQECHELVIGHQISFLSRHLSIEAVSHTEALHG--
MSMEG_4450|M.smegmatis_MC2_155 HFEPYVD-PHFEQIVTDQIDFLNRHVGAGTR----------
TH_2570|M.thermoresistible__bu HFDIYHD----PQVKSDQLDFLRQVLGTG------------
Mb2330c|M.bovis_AF2122/97 DPELLDG----RVMLDAIRRFLTETAVLGQ-----------
Rv2307c|M.tuberculosis_H37Rv DPELLDG----RVMLDAIRRFLTETAVLGQ-----------
. . ** .