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SRTEVAFPSGGDTCSAWHFAADGVRRPVVVMAHGFGGTKDSGLEPFALRFAEAGFDVFAFDYRGFGASEG TPRQSLSVRRQIDDYHAAIHAARQLDGVDPDRVALWGASFSGGHVVRVAAERADVAAVIALTPLTSGVAV SRSAMASRDTVTSLKWTLTGLKSRIAVGRGGSPTLMPLVSPVGQPGALALEGAYESYTALAGPTWRNEID SSIGLQVVGVRTTAAAKKLRCPLLVQIADFDQYVPADAVAKTAAHGRAQVHHYACDHFDVWPGNDWFDKT VTDQIAFLRRTLTRQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4372 | - | - | 100% (296) | alpha/beta hydrolase fold |
| M. gilvum PYR-GCK | Mflv_3976 | - | 3e-46 | 37.46% (299) | dienelactone hydrolase |
| M. gilvum PYR-GCK | Mflv_3465 | - | 3e-36 | 34.55% (301) | peptidase S15 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2330c | - | 1e-07 | 30.66% (137) | hypothetical protein Mb2330c |
| M. tuberculosis H37Rv | Rv2307c | - | 1e-07 | 30.66% (137) | hypothetical protein Rv2307c |
| M. leprae Br4923 | MLBr_02603 | - | 2e-05 | 25.67% (261) | hypothetical protein MLBr_02603 |
| M. abscessus ATCC 19977 | MAB_2608 | - | 9e-85 | 52.36% (296) | putative hydrolase, alpha/beta fold |
| M. marinum M | MMAR_0385 | - | 4e-50 | 38.26% (298) | hypothetical protein MMAR_0385 |
| M. avium 104 | MAV_2688 | - | 6e-07 | 42.62% (61) | alpha/beta hydrolase |
| M. smegmatis MC2 155 | MSMEG_2203 | - | 1e-121 | 68.94% (293) | alpha/beta hydrolase |
| M. thermoresistible (build 8) | TH_2707 | - | 1e-65 | 46.71% (289) | PUTATIVE putative alpha/beta hydrolase fold |
| M. ulcerans Agy99 | MUL_1035 | - | 1e-48 | 37.42% (302) | hypothetical protein MUL_1035 |
| M. vanbaalenii PYR-1 | Mvan_1972 | - | 1e-139 | 79.93% (294) | alpha/beta hydrolase fold |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4372|M.gilvum_PYR-GCK -MSRTEVAFPSGGDTCSAWHFAAD--GVRRP----VVVMAHGFGGTKDSG
Mvan_1972|M.vanbaalenii_PYR-1 -MTRSEISFRSGQDACSGWHFTSG--GALRR----VVVMAHGFGGTKDSG
MSMEG_2203|M.smegmatis_MC2_155 -MTYTEFTFHSGGQRCSAWHFPAGSGGSGNP----VVVMAHGFGGTKDSG
MAB_2608|M.abscessus_ATCC_1997 -MNRQSIRFNSHGIDCEAWLYRAQTVEDTAP----IVVMAHGVGGTKDSG
MMAR_0385|M.marinum_M MTQRQDVRFPCGEAMISAWLYRPAGADPARPV--PMLVMAHGLGAVRTMR
MUL_1035|M.ulcerans_Agy99 MTQRQDVRFPCGEALISAWLYRPAGADPARPV--PMLVMAHGLGAVRTMR
MAV_2688|M.avium_104 --------------------------------------------------
TH_2707|M.thermoresistible__bu -MSNPLRIPAEGGAMLAASHFPATSDALRGPNGRPGVVMAHGLGATRDSG
Mb2330c|M.bovis_AF2122/97 ---MSLKRCRALPVVAIVALVASGVITFIWSQQRRLIYFPSAGPVPSASS
Rv2307c|M.tuberculosis_H37Rv ---MSLKRCRALPVVAIVALVASGVIMFIWSQQRRLIYFPSAGPVPSASS
MLBr_02603|M.leprae_Br4923 -MTITRTERNFYGVGGVRIVYDVWMPDTRPR---AVIILAHGFG-EHARR
Mflv_4372|M.gilvum_PYR-GCK LEPFALRFAEAGFDVFAFDYRGFGASEG-TPRQSLSVRRQIDDYHAAIHA
Mvan_1972|M.vanbaalenii_PYR-1 LEPFAQRFAAAGIDVLAFDYRGFGASGG-VPRQSLSVRRQIDDYNAAVEA
MSMEG_2203|M.smegmatis_MC2_155 LQPFAERFSAAGLDAVAFDYRGFGASEG-EPRQSISVERQLADYDAAIRA
MAB_2608|M.abscessus_ATCC_1997 LEPFAVRLAEAGMHALAFDYRGFGASDG-FPRQHVSFTHQIGDYHAAVNM
MMAR_0385|M.marinum_M LDAYAQRFSAAGYACLVFDYRNFGDSEG-QPRQLLDIRMQLQDWAAAVAY
MUL_1035|M.ulcerans_Agy99 LDAYAQRFSAAGYACLVFDYRNFGDSEG-QPRQLLDIRMQLQDWAAAVAY
MAV_2688|M.avium_104 --------------------------------------------------
TH_2707|M.thermoresistible__bu LAGFAAALADAGADVITFDYRNFAESDG-TPRQLVSLRGQIRDYHAALRY
Mb2330c|M.bovis_AF2122/97 VLPAGRDVVVETQDGMRLGGWYFPHTSGGSGPAVLVCNGNAGDRSMRAEL
Rv2307c|M.tuberculosis_H37Rv VLPAGRDVVVETQDGMRLGGWYFPHTSGGSGPAVLVCNGNAGDRSMRAEL
MLBr_02603|M.leprae_Br4923 YDHVAHYFAAAGLATYALDLRGHGRSAG-----KRVLVRDLSEYNADFDI
Mflv_4372|M.gilvum_PYR-GCK ARQLDGVDPD--RVALWGASFSGGHVVRVAAERADVAAVIALTPLTSGVA
Mvan_1972|M.vanbaalenii_PYR-1 AKTLDGVDPS--RVGLWGASFSGGHVLRVAAERDDIGAVISLTPLTSGLA
MSMEG_2203|M.smegmatis_MC2_155 AQAMPGVDPR--KVVLWGSSFSGSHVLRAAARNTDVAAVIAMTPLTSGLA
MAB_2608|M.abscessus_ATCC_1997 ARRLPGVDPT--RIVLWGVSLAGGHVMAVAGARNDVAAVIALTPLVDGIA
MMAR_0385|M.marinum_M ARTCDGVDQA--RIGLWGTSFGGGHVIATAARLPGIAAVVAQCPFTDGIA
MUL_1035|M.ulcerans_Agy99 ARTCDGVDQA--RIGLWGTSFGGGHVIATAARLPGIAAVVAQCPFTDGIA
MAV_2688|M.avium_104 --------------------------------------------------
TH_2707|M.thermoresistible__bu LRSMPDVDAR--RVAVWGVSLSGGHVLKVAAEDPAVAAVISVTPAVDGLA
Mb2330c|M.bovis_AF2122/97 AVALHGLGLS--VLLFDYRGYGG-----NPGRPSEQGLAADARAAQEWLS
Rv2307c|M.tuberculosis_H37Rv AVALHGLGLS--VLLFDYRGYGG-----NPGRPSEQGLAADARAAQEWLS
MLBr_02603|M.leprae_Br4923 LVGIATRDHPGLKRIVAGHSMGGAIVFAYGVERPDNYDLMVLSGPAVAAQ
Mflv_4372|M.gilvum_PYR-GCK VSRSAMASRDTVTSLKWTLTGLKSRIAVGRGGSPTLMPLVSPVGQPGALA
Mvan_1972|M.vanbaalenii_PYR-1 VSRAAAASRDMVTSLRWTLTGVRSRFAVRRGGRPTMMPLVAPVGEPGALA
MSMEG_2203|M.smegmatis_MC2_155 ASRAAVTQRDVATALRWTLKGVKSRVAAAVGGAPTMMPLTAKPGEPGALA
MAB_2608|M.abscessus_ATCC_1997 AARSAMTEHSAGTLLRSAVTGLRSRLGRQQ----RTIPIVGRAGELAALT
MMAR_0385|M.marinum_M SVLAIAPT----TAIRVTARSMRDLIGSRLGRPPVMIPTAGKPGEVALMT
MUL_1035|M.ulcerans_Agy99 SVLAIAPT----TAIRVTARSMRDLIGSRLGRPPVMIPTAGKPGEVALMT
MAV_2688|M.avium_104 --------------------------------------------------
TH_2707|M.thermoresistible__bu AVATLARANGPVHLAKLVGRGLSDVLAAALGRPPVPAPIVGHPGELAALT
Mb2330c|M.bovis_AF2122/97 GQSDVDPAR-----IAYFGESLGAAVAVGLAVQRPPAALVLRSPFTSLAE
Rv2307c|M.tuberculosis_H37Rv GQSDVDPAR-----IAYFGESLGAAVAVGLAVQRPPAALVLRSPFTSLAE
MLBr_02603|M.leprae_Br4923 DMVS--PLR------AVVGKGLG-LVAPGLPVHQLEVDAISRNRAVVAAY
Mflv_4372|M.gilvum_PYR-GCK LEGAYESYTALA--GPTWRNEIDSSIGLQVVGVRTTAAAKKLRCPLLVQI
Mvan_1972|M.vanbaalenii_PYR-1 LDGAYESYTALA--GPTWRNEIDSSVGLEVVGVRTNAAAKKMRCPLLVQI
MSMEG_2203|M.smegmatis_MC2_155 LDGAYESYLSIA--GPTWRNEVDAGVGMELARVRTAAAAKALKCPVLVQI
MAB_2608|M.abscessus_ATCC_1997 SDGYYEAHLAIA--GPAWRNEIDATVGTQLVSYRPTRCASRIGCPILVQI
MMAR_0385|M.marinum_M APDAYPGYLGLMPQGTQVPNEVAARIGIKVLGYRPGRSARKIACPILFCV
MUL_1035|M.ulcerans_Agy99 APDAYPGYLGLMPQGTQVPNEVAARIGIKVLGYRPGRSARKIACPILFCV
MAV_2688|M.avium_104 -----------------------------------------MSCPILFAI
TH_2707|M.thermoresistible__bu APGAVEGMLTTA--GPSWRNAIAARLFLQMGTYRPIADVSRVQCPVLMQI
Mb2330c|M.bovis_AF2122/97 VGAVHYPWLPLR--------------RLLLDHYPSIERIASVHAPVLVIA
Rv2307c|M.tuberculosis_H37Rv VGAVHYPWLPLR--------------RLLLDHYPSIERIASVHAPVLVIA
MLBr_02603|M.leprae_Br4923 KDDPLVYHGKVP---------AGVGRVMLQVGETMTRRAPVLTTPLLVVH
: *:*.
Mflv_4372|M.gilvum_PYR-GCK ADFDQYVPADAVAKTAAHGRAQ-----VHHYACDHFDVWPGNDWFDKTVT
Mvan_1972|M.vanbaalenii_PYR-1 ADFDQYVPAAAVATTAAHGRAQ-----VHHYPCDHFDVWPGHDWFDKTVS
MSMEG_2203|M.smegmatis_MC2_155 ADFDRFVPADSVAKTAVQARAQ-----VHHYACDHFDVWPGHDWFDTAVT
MAB_2608|M.abscessus_ATCC_1997 ADFDRAAPPHAAAKAAFKARAE-----VRHYPCDHFGVYHGQECHELVIG
MMAR_0385|M.marinum_M CETDSVAPAGPTLRYAARAPRG----EVIRYPEGHFAIYLG-DAFERVVA
MUL_1035|M.ulcerans_Agy99 CETDSVAPAGPTLRYAARAPRGEVSGEVIRYPEGHFAIYLG-DAFEHVVA
MAV_2688|M.avium_104 CENDTVAPAKATQKYAAQAPRG----EIKLYDAGHFDIYVG-ADFERNVT
TH_2707|M.thermoresistible__bu ADHDQSAPPAAATRAATRLGAT-----VHRYPCDHFDVYPGTSCHDRAVA
Mb2330c|M.bovis_AF2122/97 GGSDDIVPATLSEWLVAAAAEP-----------KRYVVVPGVGHNDPELL
Rv2307c|M.tuberculosis_H37Rv GGSDDIVPATLSERLVAAAAEP-----------KRYVVVPGVGHNDPELL
MLBr_02603|M.leprae_Br4923 GSEDRLVLVDGSHRLVECVGST----------DVELKVYPGLYHEVFNEP
* . . . : *
Mflv_4372|M.gilvum_PYR-GCK D---QIAFLRRTLTRQ----------
Mvan_1972|M.vanbaalenii_PYR-1 D---QVAFLTRTFSVVRGTLID----
MSMEG_2203|M.smegmatis_MC2_155 D---QIAFLRRTLSLR----------
MAB_2608|M.abscessus_ATCC_1997 H---QISFLSRHLSIEAVSHTEALHG
MMAR_0385|M.marinum_M D---QLGFLDKHLKPAGQP-------
MUL_1035|M.ulcerans_Agy99 D---QLGFLDKHLKPAGQP-------
MAV_2688|M.avium_104 D---QLNFLSRHVPVS----------
TH_2707|M.thermoresistible__bu H---QVAFLRRVLAPAEVAS------
Mb2330c|M.bovis_AF2122/97 DGRVMLDAIRRFLTETAVLGQ-----
Rv2307c|M.tuberculosis_H37Rv DGRVMLDAIRRFLTETAVLGQ-----
MLBr_02603|M.leprae_Br4923 E---RDQVLEDVVCWILKRL------
. : .