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MSSSRDRAALREPRSVARWIRRLAVPIILGWLLLAVALNALVPQLEVVAAKNAVSMSPSNAPSMQAMADM GRLFEESDSDSIALIVLESETDQPLGDDAHEYYDGLIAALLADTENVRNIQDTWGDPLTEAAAQSSDGRA AYATLNLAGNMGETESNEAVAAVRDIVANSPPPPGVTVHVTGPAALIADVNIAGERSMALVLLVTFVVII VLLLFFYRSISTVLLLLVVVGIQLLVARGVVAALAHVGVIGLSTYATNLLISLAVAAGTDYAIFLVGRYQ EARASGADHEEAYYEMFHGTAHVVLGSGLTIAGAMLCLSFTRMPYFQSMGIPCAVGIAAGVAVALTLGPA IVTVGSRFNLLEPKRAMRIRAWRRIGTMVVRWPGPILVASLALALVGLAALPGYQTSYDDTRYVPESIPA NAGLQAATQHFTLSRMSPEILIVEADRDLRNPADFLVLDRLAKRVFAVEGVARVQAPSRPDGSPIAKTSI PFLISMQGVGQQQNMKLMQDRMDDMRTQADNLGKTLGTMRTMYGLMTRLSEVTTVMIDDFTEMQQTVHQI RDMVANFDDQFRPVRNYFYWEPHCYNIPLCWSFRSLFDSMDGISTMTESFDKALVNMETMRSLLPQMLAT FPPMIETMESMRQMMLTTYATMGGFYDQMDELTQDSTEMGKAFDEAKNDDSFYLPPEVFENEDFKRAMES FFSPDGKTVRMLVSHRGDPTTPEALARVEPIKIAAIEALKGTPLENAQIQLGGTAATFKDMSDGSRYDMM IAILSALCLVLVIMLVLTRSLVAAVVIVGTVALSLGASFGVSVLIWQHLLGVELHWMVLVMSIIALIAVG SDYNLLLVSRFKEEIGAGIKTGIIRAIGGTGSVVSVAGVVFALTMASMVVSDLKVIAQVGTTIGLGLLFD TFIVRAFMMPSIATLLGRWFWWPLVVRSRPLRPRPQQQALGVGGQQG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2705 | - | - | 100% (957) | transport protein |
| M. gilvum PYR-GCK | Mflv_3435 | - | 0.0 | 60.66% (938) | transport protein |
| M. gilvum PYR-GCK | Mflv_4418 | - | 0.0 | 60.46% (923) | transport protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0458c | mmpL4 | 0.0 | 60.63% (927) | transmembrane transport protein MmpL4 |
| M. tuberculosis H37Rv | Rv0450c | mmpL4 | 0.0 | 60.73% (927) | transmembrane transport protein MmpL4 |
| M. leprae Br4923 | MLBr_02378 | - | 0.0 | 60.97% (930) | hypothetical protein MLBr_02378 |
| M. abscessus ATCC 19977 | MAB_2301 | - | 0.0 | 63.45% (952) | putative membrane protein, mmpL |
| M. marinum M | MMAR_3174 | mmpL4_5 | 0.0 | 63.79% (939) | transmembrane transport protein MmpL4_5 |
| M. avium 104 | MAV_3249 | - | 0.0 | 58.86% (914) | Mmp14A protein |
| M. smegmatis MC2 155 | MSMEG_0225 | - | 0.0 | 59.94% (931) | MmpL4 protein |
| M. thermoresistible (build 8) | TH_3260 | - | 0.0 | 58.33% (936) | PUTATIVE MmpL4 protein |
| M. ulcerans Agy99 | MUL_0757 | mmpL5 | 0.0 | 58.97% (931) | transmembrane transport protein, MmpL5 |
| M. vanbaalenii PYR-1 | Mvan_3833 | - | 0.0 | 85.91% (937) | transport protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0458c|M.bovis_AF2122/97 -MSTKFANDSNTNARPEK---------PFIARMIHAFAVPIILGWLAVCV
Rv0450c|M.tuberculosis_H37Rv -MSTKFANDSNTNARPEK---------PFIARMIHAFAVPIILGWLAVCV
MLBr_02378|M.leprae_Br4923 -MTVKCANDLDTHTKP-----------PFVARMIHRFAVPIILVWLAIAV
MAV_3249|M.avium_104 --------------------------------------MFIILGWVALTL
Mflv_2705|M.gilvum_PYR-GCK -----MSSSRDRAALREP---------RSVARWIRRLAVPIILGWLLLAV
Mvan_3833|M.vanbaalenii_PYR-1 -----MRAHADR-DLRDP---------TPVARWIRRLAIPIILGWVLLVA
MMAR_3174|M.marinum_M -MITRVFRPSSREVRTEP---------ALLARWIRRLAIPIMLGWLAIIV
MAB_2301|M.abscessus_ATCC_1997 -----MSGSHAGRSAAEP---------TFLAKWIRRLSIPIVIGWLAIVF
MSMEG_0225|M.smegmatis_MC2_155 -MSTP-DAPTEAIPSAHG--KYTNHGG--IAKLIRTLAVPIILVWVALIA
TH_3260|M.thermoresistible__bu MTANPGHVRTDEAPTDRLDIKVSTHGPSFISTWIRRLSLPIIVGWIALIA
MUL_0757|M.ulcerans_Agy99 MTATTTDTPTDVVPPAEH------PPRPFIPRMIRTFAVPLILGWVLLIA
: ::: *: :
Mb0458c|M.bovis_AF2122/97 VVTVFVPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKEGDSDSFAMVI
Rv0450c|M.tuberculosis_H37Rv VVTVFVPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKEGDSDSFAMVI
MLBr_02378|M.leprae_Br4923 TVSVFIPSLEDVGQERSVSLSPKDAPSYIAMQKMGQVFNEGNSDSVIMIV
MAV_3249|M.avium_104 LVTFGVPRLEIVGQQHSVPLAPQDAPAVQAMQRMGRDFKESDSDSFAMLV
Mflv_2705|M.gilvum_PYR-GCK ALNALVPQLEVVAAKNAVSMSPSNAPSMQAMADMGRLFEESDSDSIALIV
Mvan_3833|M.vanbaalenii_PYR-1 ALNLLVPQLEVVAAQNAVSMSPSDAPAMQAMSDMGRLFGESDSDSIAMVV
MMAR_3174|M.marinum_M LINILVPSLQQVAADNSVSMNPAGAPSLQAIKEMGRVFGESRSDSVALIL
MAB_2301|M.abscessus_ATCC_1997 ALNTFVPQLEQVGKEHTVSLSPQSAPSMQAMKHMGKMFKESDSDSVVMIV
MSMEG_0225|M.smegmatis_MC2_155 VLNTIVPQLEEVGEMRSVSMSPDDAPSMIAMKRVGEVFEEFKSNSSVMIV
TH_3260|M.thermoresistible__bu LLNITVPQLEVVGEMRAVSMSPDEAPSMVAMKRVGELFDEGSSDSQVMIV
MUL_0757|M.ulcerans_Agy99 VLNSVVPQLEVVGQMQAVSMSPDAAPSMISMKHIGKVFREGDSDSAAMIV
:. :* *: *. .:*.: * **: :: :* * * *:* :::
Mb0458c|M.bovis_AF2122/97 IEGN--QPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDPLTAAGVQSN
Rv0450c|M.tuberculosis_H37Rv IEGN--QPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDPLTAAGVQSN
MLBr_02378|M.leprae_Br4923 LEGD--KPLGDDAHRFYDGLIRKLRADK-HVQSVQDFWGDPLTAPGAQSN
MAV_3249|M.avium_104 LEGQ--QQLGDDAHAYYDKLVRELRNDTKHVEHVQDLWGDRLTQAGAQSP
Mflv_2705|M.gilvum_PYR-GCK LESETDQPLGDDAHEYYDGLIAALLADTENVRNIQDTWGDPLTEAAAQSS
Mvan_3833|M.vanbaalenii_PYR-1 LEGE--QPLGDDAHAYYDQLIEKLEAAPDHVRNIQDMWGDPLTEAAAQST
MMAR_3174|M.marinum_M LEGR--QPLGADAHEYYDDLVTRLRADTAHVQNVQDFWGDPLTEGSAQSP
MAB_2301|M.abscessus_ATCC_1997 LEGQ--ERLGPGSHKFYDEMVARLRADTKHVQHVQDFWGDPLTEAGAQST
MSMEG_0225|M.smegmatis_MC2_155 LEGE--QPLGDEAHKYYDEIVDKLEADKTHIEHVQDFWGDPLTASGAQSS
TH_3260|M.thermoresistible__bu LEGE--EPLGADARAFYDELVKRLEADDAHVENVQDLWSDPLTATGVQSP
MUL_0757|M.ulcerans_Agy99 LEGQ--EPLGAAAHKFYDKMITKLRADTKHVQSVQDFWGDPLTATGAQSG
:*. : ** :: :** :: * ::. :** *.* ** ..**
Mb0458c|M.bovis_AF2122/97 DGKAAYVQLSLAGNQGTPLANESVEAVRSIVESTPA---------PPGIK
Rv0450c|M.tuberculosis_H37Rv DGKAAYVQLSLAGNQGTPLANESVEAVRSIVESTPA---------PPGIK
MLBr_02378|M.leprae_Br4923 DGKAAYVQLSLAGNQGELLAQESIDAVRKIVVQTPA---------PPGIT
MAV_3249|M.avium_104 DGKAVYVQLNLAGNQGTTLGQESVAAVRDVIARIPP---------PAGLK
Mflv_2705|M.gilvum_PYR-GCK DGRAAYATLNLAGNMGETESNEAVAAVRDIVANSPP---------PPGVT
Mvan_3833|M.vanbaalenii_PYR-1 DGHAAYVALNLAGNMGETKSNESVAAVRDIVADSPP---------PPGVQ
MMAR_3174|M.marinum_M DGKAAYLQLYLSGNIGDTLANESVGAVWAAVDARPP---------PPGVK
MAB_2301|M.abscessus_ATCC_1997 DGKATYVQVNLAGNMGETLSNESTEAARNIVKQLEADWTKDGNKLPDGLT
MSMEG_0225|M.smegmatis_MC2_155 DGLASYVQVYTAGNQGEALANESVKAVQDIVDSV---------QAPPGVT
TH_3260|M.thermoresistible__bu DGKSAYVQVKLAGNQGEALANESVETVREMIATVSEE------MAPEGVQ
MUL_0757|M.ulcerans_Agy99 DGKAAYVQVKLAGNQGESLANESVEAVKTIVDSL---------QAPPGVK
** : * : :** * .:*: :. : * *:
Mb0458c|M.bovis_AF2122/97 AYVTGPSALAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSIITVVLLL
Rv0450c|M.tuberculosis_H37Rv AYVTGPSALAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSIITVVLLL
MLBr_02378|M.leprae_Br4923 AWVTGASALIADMHHSGDKSMIRITATSVIVILVTLLLVYRSFITVILLL
MAV_3249|M.avium_104 AYVTGPAALFSDMQLAGDRSILKMTLIGALIIFIVLLFVYRSVTTVVLLL
Mflv_2705|M.gilvum_PYR-GCK VHVTGPAALIADVNIAGERSMALVLLVTFVVIIVLLLFFYRSISTVLLLL
Mvan_3833|M.vanbaalenii_PYR-1 VHVTGPAALTADVNIAGESSMALILLVTFVVIIVLLLFFYRSITTVVLLL
MMAR_3174|M.marinum_M VYVTGPAALQADLIHSAERTVRTIKIATFTVIIVLMLFFFRSVPTVLVLL
MAB_2301|M.abscessus_ATCC_1997 VYVTGPGALQTDMNHAGDGSLQLITGLTFLVIVVMLLFFYRSIFTVIMVF
MSMEG_0225|M.smegmatis_MC2_155 AYVTGPAAMSADQQIAGDRSMRMIEALTFTVIIIMLLMVYRSIITVILSL
TH_3260|M.thermoresistible__bu AFVTGGAAMSADQQEAGDSSLRVIEALTFLVITTMLLFVYRSVITVLIAL
MUL_0757|M.ulcerans_Agy99 VYVTGSAALVADQQLAGDRSLQLIEMVTFTVIIVMLLLVYRSIITAAIML
. *** .*: :* :.: :: : :* :*:.:**. *. : :
Mb0458c|M.bovis_AF2122/97 ITVGVELTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFIIG
Rv0450c|M.tuberculosis_H37Rv ITVGVELTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFIIG
MLBr_02378|M.leprae_Br4923 FTVGIESAVARGVVALLGHTGLIGLSTFAVNLLTSLAIAAGTDYGIFITG
MAV_3249|M.avium_104 LTVGIEVFAARGVIAFVANNNLMPLSTFAVNLLVALAMAAGTDYAIFFFG
Mflv_2705|M.gilvum_PYR-GCK VVVGIQLLVARGVVAALAHVGVIGLSTYATNLLISLAVAAGTDYAIFLVG
Mvan_3833|M.vanbaalenii_PYR-1 IMVGVQMSVARGVVAALGHFQVIGLSTFAVNLLISLAVAAGTDYAIFLVG
MMAR_3174|M.marinum_M GVVGIQLSAATGVAAVIGYLGVVELSTFAVNLVVAMAIATGTDYAIFLIG
MAB_2301|M.abscessus_ATCC_1997 MLVGIQLSAARGVIAFLGNTEIIGLSTFAVNLLVMLSIAAGTDYAIFLIG
MSMEG_0225|M.smegmatis_MC2_155 VMVVFSLAAARGVIAFLGYYEIIGLSTFATNLLVTLAIAAATDYAIFLIG
TH_3260|M.thermoresistible__bu FMVLIGLLTTRGVVAFLGYHNIIGLSTFATSLLVTLAIAIAVDYAIFLIG
MUL_0757|M.ulcerans_Agy99 TMVVLGLLATRGGVAFLGYHRIIGLSTFATNLLVVLAIAAATDYAIFLIG
* . .: * * :. : *:*:*..*: :::* ..**.**: *
Mb0458c|M.bovis_AF2122/97 RYQEARQAGEDKEAAYYTMYRGTAHVILGSGLTITGATFCLSFARMPYFQ
Rv0450c|M.tuberculosis_H37Rv RYQEARQAGEDKEAAYYTMYRGTAHVILGSGLTIAGATFCLSFARMPYFQ
MLBr_02378|M.leprae_Br4923 RYQEARQANENKEAAFYTMYRGTFHVILGSGLTISGATFCLSFARMPYFQ
MAV_3249|M.avium_104 RYQEAREAGEDRATAYFTTYRSVAPVVLGSGLTIAGAMLCLSFTRMPIFQ
Mflv_2705|M.gilvum_PYR-GCK RYQEARASGADHEEAYYEMFHGTAHVVLGSGLTIAGAMLCLSFTRMPYFQ
Mvan_3833|M.vanbaalenii_PYR-1 RYQEARASGADPEAAYYEMFGGTAHVVLGSGLTIAGAMYCLSFARMPYFQ
MMAR_3174|M.marinum_M RYQEARAAGVDRESAYYEMWHGTAHVVLASGLTIAGAALCMSLTRMPYLQ
MAB_2301|M.abscessus_ATCC_1997 RYQEARAMGADKEAAYYEMFHGTAHVILGSGMTIAGAMYCLSFTRMPYFQ
MSMEG_0225|M.smegmatis_MC2_155 RYQEARSVGESREQAYYTMFHSTAHVVLGSGMTIAGATLCLHFTRMPYFQ
TH_3260|M.thermoresistible__bu RYQEARSVGADRATAYHTMFGGTAHVILASGLTIAGATFCLSFTRLPYFQ
MUL_0757|M.ulcerans_Agy99 RYQEARGLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFTRLPYFQ
****** . . *:. : .. *:*.**:**:** *: ::*:* :*
Mb0458c|M.bovis_AF2122/97 TLGIPCAVGMLVAVAVALTLGPAVLHVGSRFG-LFDPKRLLKVRGWRRVG
Rv0450c|M.tuberculosis_H37Rv TLGIPCAVGMLVAVAVALTLGPAVLHVGSRFG-LFDPKRLLKVRGWRRVG
MLBr_02378|M.leprae_Br4923 TLGVPCAVGMLIAVAVALTLGPAVLTVGSRFG-LFEPKRLIKVRGWRRIG
MAV_3249|M.avium_104 TMGLPCSVGMLISVFIALTLVPAVLTVGGGFG-LFDPKRAIGFGRWRRIG
Mflv_2705|M.gilvum_PYR-GCK SMGIPCAVGIAAGVAVALTLGPAIVTVGSRFN-LLEPKRAMRIRAWRRIG
Mvan_3833|M.vanbaalenii_PYR-1 SMGVPCAVGILAGVAVALTLGPAIVTVGSRFG-LLEPKRAMRIRAWRRVG
MMAR_3174|M.marinum_M SLGVPTAVAMLVALSVALTLGPAAVTVASRFG-LLEPKRAIRIRFWRRIG
MAB_2301|M.abscessus_ATCC_1997 TLGVPCSVGLLVGVLVSLTLGPALITIGSRFG-LFEPKRAMRIRSWRKIG
MSMEG_0225|M.smegmatis_MC2_155 SLGIPLAIGMTVVVLTALAVGPAIITVASRFGKTLEPKRAMRTRGWRKVG
TH_3260|M.thermoresistible__bu SLGPPLAIGMIVLIVTSLTMGPAIITVATRFG-LLEPKRAARVRFWRKVG
MUL_0757|M.ulcerans_Agy99 TLGVPLAIGMVIVVATALTLGPALIAVMSRFGKLLEPKRMARVRGWRKIG
::* * ::.: : :*:: ** : : *. ::*** **::*
Mb0458c|M.bovis_AF2122/97 TVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPANQGYAA
Rv0450c|M.tuberculosis_H37Rv TVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPANQGYAA
MLBr_02378|M.leprae_Br4923 TVVVRWPLPILITTCAIAMVGLLALPGYRTNYKDRAYLPASIPANQGFAA
MAV_3249|M.avium_104 TAIVRWPAPILTATIAVALVGLVTLPGYKTSYNNRLYMPDSVPANVGYAA
Mflv_2705|M.gilvum_PYR-GCK TMVVRWPGPILVASLALALVGLAALPGYQTSYDDTRYVPESIPANAGLQA
Mvan_3833|M.vanbaalenii_PYR-1 ATVVRWPGPILVASLALALIGLAALPGYKTSYDDTRYIPESIPANAGLQA
MMAR_3174|M.marinum_M TAVVRWPAPILLASLAAALVGLIALPFYQPSYNDRRYIPGDIEANAGYAA
MAB_2301|M.abscessus_ATCC_1997 TTIVRWPGPVLAAAMAIAIIGLAALPGYRTSYDDKKYIPKDIPANAGFQA
MSMEG_0225|M.smegmatis_MC2_155 AAVVRWPGPILVAAVGLSMIGLLALPGYRTNYNDRDYQPADLPANSGYAA
TH_3260|M.thermoresistible__bu ASVVRWPGPIMVTTVAVTLVGLLALPGYRTNYNDRNYLPASFPSNAGYEA
MUL_0757|M.ulcerans_Agy99 AAIVRWPGPILIGAVALALVGLLTLPGYKTNYNDRNYLPADLPANEGYSA
: :**** *:: : . :::** :** *:..*.: * * . :* * *
Mb0458c|M.bovis_AF2122/97 ADRHFSQARMKPEILMIESDHDMRNPADFLVLDKLAKGIFRVPGISRVQA
Rv0450c|M.tuberculosis_H37Rv ADRHFSQARMKPEILMIESDHDMRNPADFLVLDKLAKGIFRVPGISRVQA
MLBr_02378|M.leprae_Br4923 ADRHFPQARMKPEILMIESDHDMRNPADFLILDKLARGIFRVPGISRVQA
MAV_3249|M.avium_104 ADRHFTQSRMMPELLMIESDHDMRNPADFLVLHRLAKGVFGVHGISRVQG
Mflv_2705|M.gilvum_PYR-GCK ATQHFTLSRMSPEILIVEADRDLRNPADFLVLDRLAKRVFAVEGVARVQA
Mvan_3833|M.vanbaalenii_PYR-1 ATKYFSLSRMSPEVLIVEADRDLRNSSDFLILDRLAKRVFNVEGVARVQA
MMAR_3174|M.marinum_M AEQHFSAARMNPEVLLVEADHDLRNPADFLVIDKLAKAIFRVPGVARVQA
MAB_2301|M.abscessus_ATCC_1997 ADRHFSQARMNPEMLLIESDHDMRNSADFLVIDKIAKAVFRVPGIARVQA
MSMEG_0225|M.smegmatis_MC2_155 ADRHFSQARMNPELLMIESDHDLRNSADFLVIERIAKRVVGVPGVSRVQA
TH_3260|M.thermoresistible__bu AERHFDPARLNPELLLIESDHDLRNPADFLVIEKIAKAVFQVEGISRVQG
MUL_0757|M.ulcerans_Agy99 AERHFSQARMNPEVLMVESDHDMRNSSDFLVINKIAKAIFGVEGISRVQA
* ::* :*: **:*::*:*:*:**.:***::.::*: :. * *::***.
Mb0458c|M.bovis_AF2122/97 ITRPEGTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQADEMATTI
Rv0450c|M.tuberculosis_H37Rv ITRPEGTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQADEMATTI
MLBr_02378|M.leprae_Br4923 ITRPDGTAMDHTSIPFQISMQNAGQVQTMKYQKDRMNDLLRQAENMAETI
MAV_3249|M.avium_104 ITRPEGTPIQHTSIPFLLSMQQATMHQDIQYMKARMDDMLVQADLMRKQI
Mflv_2705|M.gilvum_PYR-GCK PSRPDGSPIAKTSIPFLISMQGVGQQQNMKLMQDRMDDMRTQADNLGKTL
Mvan_3833|M.vanbaalenii_PYR-1 PSRPDGAPIAHTSIPFLISMQGVGQQQNMKLMKDRIADMRVQADDIGETI
MMAR_3174|M.marinum_M ITRPDGAPIQHTSIPFMMSMQGVGLQQNMKLMFDRIDDMKAQAESLGNTV
MAB_2301|M.abscessus_ATCC_1997 ITRPQGTPIEHSSIPFLISMQSVGQRQNMKLMKDRMADMKVQADKMGENV
MSMEG_0225|M.smegmatis_MC2_155 ITRPQGTPIEHTSIPFTISMQGTTQTMNQKYMQDRMADMLVQADQMQVTV
TH_3260|M.thermoresistible__bu ITRPEGTPIEHSSIPFMISQQGTLQILNQQYMQDRMADMLVQADEMQLMI
MUL_0757|M.ulcerans_Agy99 ITRPDGKPIEHTSIPFLISMQGTSQKLTEKYNQDLTTSMLQQVNDIQTNI
:**:* .: ::**** :* * . : .: *.: : :
Mb0458c|M.bovis_AF2122/97 AVLTRMHSLMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDFWRPIRS
Rv0450c|M.tuberculosis_H37Rv AVLTRMHSLMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDFWRPIRS
MLBr_02378|M.leprae_Br4923 ASMRRMHQLMALLTENTHHILNDTVEMQKTTSKLRDEIANFDDFWRPIRS
MAV_3249|M.avium_104 EIMRHIYELQKRLTDITHDSIVKTKEMAAVLWELRDKMSDFEDFWRPLRS
Mflv_2705|M.gilvum_PYR-GCK GTMRTMYGLMTRLSEVTTVMIDDFTEMQQTVHQIRDMVANFDDQFRPVRN
Mvan_3833|M.vanbaalenii_PYR-1 ATMKTMYGLMTKFSNITTVMIDDMTEMRDTVHQIRDMVATFDDQFRPIRN
MMAR_3174|M.marinum_M AIMKRMQASMSRMAGVGDGLVVDMDDMQTAVRDARDSLADFEDFFRPIRN
MAB_2301|M.abscessus_ATCC_1997 VIMKRTLANMTTMAGITHSLVGDMHTLQGTIHEMRDSISNFDDWFRPIRN
MSMEG_0225|M.smegmatis_MC2_155 DTMTKMIALMEQMRDTMNSMVGKMHGMVDDIKELRDNISDFDDFFRPIRN
TH_3260|M.thermoresistible__bu DTMDKMIALMEEMVETTDNMVRDMDEMAAHVAEMRDSISEFDDFFRPIRN
MUL_0757|M.ulcerans_Agy99 DQMERMHDLTQQMADVTHQMVIQMKGMVVDVEELRNHIADFDDFFRPIRS
: : : . : . *: :: *:* :**:*.
Mb0458c|M.bovis_AF2122/97 YFYWEKHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREMDRLMPQ
Rv0450c|M.tuberculosis_H37Rv YFYWEKHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREMDRLMPQ
MLBr_02378|M.leprae_Br4923 YFYWERHCFNIPICWSFRSIFDALDGVDQIDERLNSIVGDIKNMDLLMPQ
MAV_3249|M.avium_104 YFYWEKHCYDIPICWSLRNIFETLDGVDTLSDKMTYLLQDLDHMDRLMPQ
Mflv_2705|M.gilvum_PYR-GCK YFYWEPHCYNIPLCWSFRSLFDSMDGISTMTESFDKALVNMETMRSLLPQ
Mvan_3833|M.vanbaalenii_PYR-1 YFYWEPHCYNIPLCWSFRSLFDSMDGISVMTDTFDKAVANMDEMKALLPQ
MMAR_3174|M.marinum_M YFHWEPHCFDIPVCWALRSVSDSVDGIDAMTDQMDRMIKGMTDLNALIPE
MAB_2301|M.abscessus_ATCC_1997 YLYWEKHCFDIPMCWAMRSIFDTLDKIDEMTETMDGMVVNMERMDTLMPK
MSMEG_0225|M.smegmatis_MC2_155 YLYWEPHCYNIPMCYSLRSIFDTMDGIDTMTADFEQIVPDMDRMNALIPV
TH_3260|M.thermoresistible__bu YFYWEPHCYNIPVCWAMRSVFDTLDGINTMTDDIQNMLPHMHRLNDLMPQ
MUL_0757|M.ulcerans_Agy99 YFYWEKHCFDIPVCWSLRSVFDTLDGVDLMTEDINNLLPLMERLDTLMPQ
*::** **:.**:*:::*.: :::* :. : : : : : *:*
Mb0458c|M.bovis_AF2122/97 MVAQIPPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMGKAFDAA
Rv0450c|M.tuberculosis_H37Rv MVAQIPPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMGKAFDAA
MLBr_02378|M.leprae_Br4923 MLEQFPPMIESMESMRTIMLTMHSTMSGIFDQMNELSDNANTMGKAFDTA
MAV_3249|M.avium_104 LLEQYPPMIAMSEDMLRMMLTNHSTMSGIIGQMDSNNKDATAMGEAFDAS
Mflv_2705|M.gilvum_PYR-GCK MLATFPPMIETMESMRQMMLTTYATMGGFYDQMDELTQDSTEMGKAFDEA
Mvan_3833|M.vanbaalenii_PYR-1 MLATFPPMIETMESMRQMMLTTYATMGGFYDQMDELTRDSTEMGKAFDAA
MMAR_3174|M.marinum_M MIAQFPPMIATMESMQQMMLTMHSTMSGMYRQMDELSHGAAEMGKAFDAA
MAB_2301|M.abscessus_ATCC_1997 MVSDMSAMIPIMEDMQRMMLTQHSTMSGFYNQMDEMSQNSTAMGKAFDAA
MSMEG_0225|M.smegmatis_MC2_155 MIANMEPMITTMKTMKTMMLTMQATNAGLQDQMAAMQENSTAMGEAFDKA
TH_3260|M.thermoresistible__bu MLTLLPTTVATMKTMRSMLLTMQATNAGLQDQMAEMQENANAMGEAFDQA
MUL_0757|M.ulcerans_Agy99 MTAMMPEMIQTMKSMKAQMLSMHSTQQGLQDQMAAMQEDSSAMGEAFDSS
: : : * :*: :* *: ** .: **:*** :
Mb0458c|M.bovis_AF2122/97 KNDDSFYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQSPEGIK
Rv0450c|M.tuberculosis_H37Rv KNDDSFYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQSPEGIK
MLBr_02378|M.leprae_Br4923 KNDDSFYLPPEVFKNTDFKRAMKSFLSSDGHAARFIILHRGDPASVAGIA
MAV_3249|M.avium_104 KNDDSFYLPPDIFDNADFKKAMSQFLSPDGKAARFIISHRGDPATSEALN
Mflv_2705|M.gilvum_PYR-GCK KNDDSFYLPPEVFENEDFKRAMESFFSPDGKTVRMLVSHRGDPTTPEALA
Mvan_3833|M.vanbaalenii_PYR-1 KNDDSFYLPPEVFENEDFKRAMESFFSPDGKTVRMLIAHRGNPTTDEALQ
MMAR_3174|M.marinum_M RNDDSFYLPSEVFDNPDFRRAMDLFISPDGKSLRMIISHRGDPASAEGIS
MAB_2301|M.abscessus_ATCC_1997 KNDDSFYLPPEIFDNADFKRGMKSFLSPDGKAVRMIISHRGDPATPEGLS
MSMEG_0225|M.smegmatis_MC2_155 KNDDSFYLPPETFDNPDFKRGMKMFLSPDGHAVRFIISHEGDPMSPEGIQ
TH_3260|M.thermoresistible__bu RNDDSFYLPPEAFDNPDFQRGLEQFLSPDGHAVRFIISHQGDPMTPEGLA
MUL_0757|M.ulcerans_Agy99 RNDDSFYLPPEVFNNPDFKRGLEQFLSPDGHAVRFIISHEGDPMSQAGIN
:********.: *.* **::.:. *:*.**:: *::: *.*:* : .:
Mb0458c|M.bovis_AF2122/97 SIDAIRTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAISS
Rv0450c|M.tuberculosis_H37Rv SIDAIRTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAISS
MLBr_02378|M.leprae_Br4923 SINAIRTAAEEALKGTPLEDTKIYLAGTAAVFKDIDEGANWDLVIAGISS
MAV_3249|M.avium_104 RIDKIRSAAEEALKNTPLENAKIYLAGTASTFKDFRDGSTYDLFIAGVGA
Mflv_2705|M.gilvum_PYR-GCK RVEPIKIAAIEALKGTPLENAQIQLGGTAATFKDMSDGSRYDMMIAILSA
Mvan_3833|M.vanbaalenii_PYR-1 RVEPIKIAAIEALKGTPLENAQIQLGGTAATFKDMSDGSRYDLLIAVISA
MMAR_3174|M.marinum_M RVDPIKLAAIEALKGTPLENAKVSLGGTASVYHDLSEGTRYDLVIAVIAT
MAB_2301|M.abscessus_ATCC_1997 HVEPIKQAAIEAVKGTPLEDAKIELGGTAAVFKDMSDGAKYDLMIAGISA
MSMEG_0225|M.smegmatis_MC2_155 KIDDIKLAAKEAIKGTPLEGSKIYLGGTAATFKDMQEGANYDLIIAGIAA
TH_3260|M.thermoresistible__bu KIEPIKKAAVEAIKGTPLEGSRVYLGGTAAVFKDMSDGTKYDLIIAAIAA
MUL_0757|M.ulcerans_Agy99 HIDKIKTAAKEAIKGTPLEGSTIYLGGTVAMFKDLSDGNTFDLMIAGISA
:: *: ** *::*.****.: : *.**.: ::*: :* :*:.** :.:
Mb0458c|M.bovis_AF2122/97 LCLIFIIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHILAIHLHW
Rv0450c|M.tuberculosis_H37Rv LCLIFIIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHILAIHLHW
MLBr_02378|M.leprae_Br4923 LCLIFIIMLIITRAFVAAAVIVGTVALSLGASFGLSVLLWQHILGIELHY
MAV_3249|M.avium_104 LCLIFIIMLILTRSFIAALVIVGTVTLSLGASFGLSVLIWQYIFGIQLYW
Mflv_2705|M.gilvum_PYR-GCK LCLVLVIMLVLTRSLVAAVVIVGTVALSLGASFGVSVLIWQHLLGVELHW
Mvan_3833|M.vanbaalenii_PYR-1 LCLVLMIMLVLTRSLVAALVIVGTVTLSLGASFGISILIWQHIVGIELHW
MMAR_3174|M.marinum_M VCLIFAIMLLITRSLVAAMVIVGTVLLSLGASVGLSVLLWQYIVGLPLQW
MAB_2301|M.abscessus_ATCC_1997 LCLIFLIMLLITRSFVASLVIVGTVALSLGASFGLSVIIWQYILGIELHW
MSMEG_0225|M.smegmatis_MC2_155 LCLIFIIMLIITRAVVASAVIVGTVVISLGSAFGLSVLIWQHLVGLELHW
TH_3260|M.thermoresistible__bu VCLIFIIMLILTRAVVAAAVIVGTVTLSLAASFGVSVLIWQYIVGLEMHW
MUL_0757|M.ulcerans_Agy99 LCLIFIIMLIITRSVVAAAVIVGTVVLSLGASFGLSVLIWQHVLGIELHW
:**:: ***::**:.:*: ****** :**.::.*:*:::**::..: : :
Mb0458c|M.bovis_AF2122/97 LVLAMSVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVVTN
Rv0450c|M.tuberculosis_H37Rv LVLAMSVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVVTN
MLBr_02378|M.leprae_Br4923 LVLAMSVIVLLAVGSDYNLLLVSRFKQEIQAGLKTGIIRSMGGTGKVVTN
MAV_3249|M.avium_104 MVLPMSVIVLLAVGSDYNLLLVSRMKEEISAGINTGIIRAMGGTGKVVTN
Mflv_2705|M.gilvum_PYR-GCK MVLVMSIIALIAVGSDYNLLLVSRFKEEIGAGIKTGIIRAIGGTGSVVSV
Mvan_3833|M.vanbaalenii_PYR-1 MVLALSIIALIAVGSDYNLLLVSRFKEEIPAGIKTGIIRAIGGTGSVVTV
MMAR_3174|M.marinum_M MVMSMAVIILLAVGADYNLMMVARFKEEMPAGLKTGIIRAMGGAGSVVTA
MAB_2301|M.abscessus_ATCC_1997 LVMQMAIIVLLAVGSDYNLLLVSRLKEELHGGLKTGIIRSMGGTGSVVTS
MSMEG_0225|M.smegmatis_MC2_155 MVLAMAVIVLLAVGADYNLLLVSRIKEEIHAGLDTGMIRAMGGSGSVVTA
TH_3260|M.thermoresistible__bu MVFPMALIILLAVGADYNLLVVARLREEIPAGLNTGMIRAMGGSGSVVTA
MUL_0757|M.ulcerans_Agy99 LVLAMAVIILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGSGSVVTA
:*: :::* *:***:****::*:*:::*: .*:.**:**::**:*.**:
Mb0458c|M.bovis_AF2122/97 AGLVFAVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAALL
Rv0450c|M.tuberculosis_H37Rv AGLVFAVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAALL
MLBr_02378|M.leprae_Br4923 AGLVFAFTMASMVVSDLRVIGQVGTTIGLGLLFDTLIVRSFMMPSIAALL
MAV_3249|M.avium_104 AGLVFAFTMASMVVSDLRIIGQVGTTIGLGLMFDTLIVRSFMTPTIAALL
Mflv_2705|M.gilvum_PYR-GCK AGVVFALTMASMVVSDLKVIAQVGTTIGLGLLFDTFIVRAFMMPSIATLL
Mvan_3833|M.vanbaalenii_PYR-1 AGVVFALTMASMVVSDLRVMAQVGTTIGLGLLFDTFIVRAFMMPAIATLL
MMAR_3174|M.marinum_M AGLVFAFTMTSMVVSDLRTIGQIGTFIGLGLLFDTLIVRSFMVPSIAALL
MAB_2301|M.abscessus_ATCC_1997 AGLVFAFTMAVMVVSDLRIIGQVGTTIALGLLFDTLIVRSFMTPAVATLL
MSMEG_0225|M.smegmatis_MC2_155 AGLVFAFTMMSMAVSELAIIGQVGTTIGLGLLFDTLVIRSFMTPSIAALL
TH_3260|M.thermoresistible__bu AGLVFGLTMMVMVVSDLTVMGQVGTTIGLGLLFDTFVVRSFMMPSIATLL
MUL_0757|M.ulcerans_Agy99 AGLVFAFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTPSIAALL
**:**..** :.**:* :.*:** *.:**:***:::*:** *::*:**
Mb0458c|M.bovis_AF2122/97 GRWFWWPLRVRSRPARTPTVPSETQPAGRPLAMSSDRLG-----------
Rv0450c|M.tuberculosis_H37Rv GRWFWWPLRVRSRPARTPTVPSETQPAGRPLAMSSDRLG-----------
MLBr_02378|M.leprae_Br4923 GRWFWWPQQGRTRPLLTVAAPVGLPPD-RSLVYSD---------------
MAV_3249|M.avium_104 GRWFWWPQLVRRRPASQLLRSEGTRRSVRVLLHQNDDADADTAEIPVPRP
Mflv_2705|M.gilvum_PYR-GCK GRWFWWPLVVRSRPLRPR-------PQQQALGVGGQQG------------
Mvan_3833|M.vanbaalenii_PYR-1 GRWFWWPLVVRSRPLRLP-------PRT----------------------
MMAR_3174|M.marinum_M GRWFWWPINVRTRPARAR-------PVRPQA-------------------
MAB_2301|M.abscessus_ATCC_1997 GRWFWWPLNVRTRPLPPPRTTVAADPTPPPVPVGPGHGDDPITTEFPRPS
MSMEG_0225|M.smegmatis_MC2_155 GKWFWWPQMVRRRPKPSPWPKPIQREPADAVN------------------
TH_3260|M.thermoresistible__bu GRWFWWPQFVRKRPVPQPWPSVPPRGPATTDRVSV---------------
MUL_0757|M.ulcerans_Agy99 GKWFWWPQVVRQRPAPQPWPTPAPTPPPATTSV-----------------
*:***** * **
Mb0458c|M.bovis_AF2122/97 --
Rv0450c|M.tuberculosis_H37Rv --
MLBr_02378|M.leprae_Br4923 --
MAV_3249|M.avium_104 TA
Mflv_2705|M.gilvum_PYR-GCK --
Mvan_3833|M.vanbaalenii_PYR-1 --
MMAR_3174|M.marinum_M --
MAB_2301|M.abscessus_ATCC_1997 V-
MSMEG_0225|M.smegmatis_MC2_155 --
TH_3260|M.thermoresistible__bu --
MUL_0757|M.ulcerans_Agy99 --