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RAHADRDLRDPTPVARWIRRLAIPIILGWVLLVAALNLLVPQLEVVAAQNAVSMSPSDAPAMQAMSDMGR LFGESDSDSIAMVVLEGEQPLGDDAHAYYDQLIEKLEAAPDHVRNIQDMWGDPLTEAAAQSTDGHAAYVA LNLAGNMGETKSNESVAAVRDIVADSPPPPGVQVHVTGPAALTADVNIAGESSMALILLVTFVVIIVLLL FFYRSITTVVLLLIMVGVQMSVARGVVAALGHFQVIGLSTFAVNLLISLAVAAGTDYAIFLVGRYQEARA SGADPEAAYYEMFGGTAHVVLGSGLTIAGAMYCLSFARMPYFQSMGVPCAVGILAGVAVALTLGPAIVTV GSRFGLLEPKRAMRIRAWRRVGATVVRWPGPILVASLALALIGLAALPGYKTSYDDTRYIPESIPANAGL QAATKYFSLSRMSPEVLIVEADRDLRNSSDFLILDRLAKRVFNVEGVARVQAPSRPDGAPIAHTSIPFLI SMQGVGQQQNMKLMKDRIADMRVQADDIGETIATMKTMYGLMTKFSNITTVMIDDMTEMRDTVHQIRDMV ATFDDQFRPIRNYFYWEPHCYNIPLCWSFRSLFDSMDGISVMTDTFDKAVANMDEMKALLPQMLATFPPM IETMESMRQMMLTTYATMGGFYDQMDELTRDSTEMGKAFDAAKNDDSFYLPPEVFENEDFKRAMESFFSP DGKTVRMLIAHRGNPTTDEALQRVEPIKIAAIEALKGTPLENAQIQLGGTAATFKDMSDGSRYDLLIAVI SALCLVLMIMLVLTRSLVAALVIVGTVTLSLGASFGISILIWQHIVGIELHWMVLALSIIALIAVGSDYN LLLVSRFKEEIPAGIKTGIIRAIGGTGSVVTVAGVVFALTMASMVVSDLRVMAQVGTTIGLGLLFDTFIV RAFMMPAIATLLGRWFWWPLVVRSRPLRLPPRT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3833 | - | - | 100% (944) | transport protein |
| M. vanbaalenii PYR-1 | Mvan_3189 | - | 0.0 | 61.53% (928) | transport protein |
| M. vanbaalenii PYR-1 | Mvan_1936 | - | 0.0 | 59.39% (921) | transport protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0458c | mmpL4 | 0.0 | 61.49% (927) | transmembrane transport protein MmpL4 |
| M. gilvum PYR-GCK | Mflv_2705 | - | 0.0 | 85.91% (937) | transport protein |
| M. tuberculosis H37Rv | Rv0450c | mmpL4 | 0.0 | 61.60% (927) | transmembrane transport protein MmpL4 |
| M. leprae Br4923 | MLBr_02378 | - | 0.0 | 60.73% (927) | hypothetical protein MLBr_02378 |
| M. abscessus ATCC 19977 | MAB_2301 | - | 0.0 | 65.09% (951) | putative membrane protein, mmpL |
| M. marinum M | MMAR_3174 | mmpL4_5 | 0.0 | 63.47% (939) | transmembrane transport protein MmpL4_5 |
| M. avium 104 | MAV_2510 | - | 0.0 | 58.41% (928) | MmpL4 protein |
| M. smegmatis MC2 155 | MSMEG_3496 | - | 0.0 | 60.15% (931) | MmpL4 protein |
| M. thermoresistible (build 8) | TH_3260 | - | 0.0 | 59.16% (933) | PUTATIVE MmpL4 protein |
| M. ulcerans Agy99 | MUL_0757 | mmpL5 | 0.0 | 59.87% (932) | transmembrane transport protein, MmpL5 |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_2510|M.avium_104 MST-----TFDDTRTDAIPVV--KEPVREKIPRFIRAFAVPIIIGWIALI
MSMEG_3496|M.smegmatis_MC2_155 MSN-----PSHDAPTDAMGVSGPKHARPGGIAKWIRVLAVPIILVWVAII
MUL_0757|M.ulcerans_Agy99 MTA-----TTTDTPTDVVPPA--EHPPRPFIPRMIRTFAVPLILGWVLLI
TH_3260|M.thermoresistible__bu MTANPGHVRTDEAPTDRLDIKVSTHGP-SFISTWIRRLSLPIIVGWIALI
Mb0458c|M.bovis_AF2122/97 MSTK----FANDSNTNARPEK-------PFIARMIHAFAVPIILGWLAVC
Rv0450c|M.tuberculosis_H37Rv MSTK----FANDSNTNARPEK-------PFIARMIHAFAVPIILGWLAVC
MLBr_02378|M.leprae_Br4923 MTVK----CANDLDTHTKP---------PFVARMIHRFAVPIILVWLAIA
Mvan_3833|M.vanbaalenii_PYR-1 --------MRAHADR-DLRDP-------TPVARWIRRLAIPIILGWVLLV
Mflv_2705|M.gilvum_PYR-GCK --------MSSSRDRAALREP-------RSVARWIRRLAVPIILGWLLLA
MMAR_3174|M.marinum_M MITR----VFRPSSREVRTEP-------ALLARWIRRLAIPIMLGWLAII
MAB_2301|M.abscessus_ATCC_1997 --------MSGSHAGRSAAEP-------TFLAKWIRRLSIPIVIGWLAIV
:. *: :::*::: *: :
MAV_2510|M.avium_104 AVLNVVVPQLDEVGKMRSVEMTPDDAQSVVATKRMGAVFNEYKSNSSVMI
MSMEG_3496|M.smegmatis_MC2_155 AVLNTVVPQLDVVGEMRSVSMSPDDAPSVIAMKRVGEVFEEFKSNSSVMI
MUL_0757|M.ulcerans_Agy99 AVLNSVVPQLEVVGQMQAVSMSPDAAPSMISMKHIGKVFREGDSDSAAMI
TH_3260|M.thermoresistible__bu ALLNITVPQLEVVGEMRAVSMSPDEAPSMVAMKRVGELFDEGSSDSQVMI
Mb0458c|M.bovis_AF2122/97 VVVTVFVPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKEGDSDSFAMV
Rv0450c|M.tuberculosis_H37Rv VVVTVFVPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKEGDSDSFAMV
MLBr_02378|M.leprae_Br4923 VTVSVFIPSLEDVGQERSVSLSPKDAPSYIAMQKMGQVFNEGNSDSVIMI
Mvan_3833|M.vanbaalenii_PYR-1 AALNLLVPQLEVVAAQNAVSMSPSDAPAMQAMSDMGRLFGESDSDSIAMV
Mflv_2705|M.gilvum_PYR-GCK VALNALVPQLEVVAAKNAVSMSPSNAPSMQAMADMGRLFEESDSDSIALI
MMAR_3174|M.marinum_M VLINILVPSLQQVAADNSVSMNPAGAPSLQAIKEMGRVFGESRSDSVALI
MAB_2301|M.abscessus_ATCC_1997 FALNTFVPQLEQVGKEHTVSLSPQSAPSMQAMKHMGKMFKESDSDSVVMI
:. :*.*: *. .:*.:.* * : : :* :* * *:* ::
MAV_2510|M.avium_104 VLEGQ--QPLGADAHAYYDEIVRRLNADTKHVEHVQDMWSDPLTGAGAQS
MSMEG_3496|M.smegmatis_MC2_155 VLEGE--QPLGDEAHKYYDEIVDKLEADPAHVEHVQDFWGDPLTASGAQS
MUL_0757|M.ulcerans_Agy99 VLEGQ--EPLGAAAHKFYDKMITKLRADTKHVQSVQDFWGDPLTATGAQS
TH_3260|M.thermoresistible__bu VLEGE--EPLGADARAFYDELVKRLEADDAHVENVQDLWSDPLTATGVQS
Mb0458c|M.bovis_AF2122/97 IIEGN--QPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDPLTAAGVQS
Rv0450c|M.tuberculosis_H37Rv IIEGN--QPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDPLTAAGVQS
MLBr_02378|M.leprae_Br4923 VLEGD--KPLGDDAHRFYDGLIRKLRADK-HVQSVQDFWGDPLTAPGAQS
Mvan_3833|M.vanbaalenii_PYR-1 VLEGE--QPLGDDAHAYYDQLIEKLEAAPDHVRNIQDMWGDPLTEAAAQS
Mflv_2705|M.gilvum_PYR-GCK VLESETDQPLGDDAHEYYDGLIAALLADTENVRNIQDTWGDPLTEAAAQS
MMAR_3174|M.marinum_M LLEGR--QPLGADAHEYYDDLVTRLRADTAHVQNVQDFWGDPLTEGSAQS
MAB_2301|M.abscessus_ATCC_1997 VLEGQ--ERLGPGSHKFYDEMVARLRADTKHVQHVQDFWGDPLTEAGAQS
::*. : ** :: :** :: * * :*. :** *.**** ..**
MAV_2510|M.avium_104 NDGKASYVQVYLAGNQGEALANESVESVQNIVKSV---------QAPNGV
MSMEG_3496|M.smegmatis_MC2_155 PDGLASYVQVYTRGNQGEALANESVEAVQDIVESV---------PAPPGV
MUL_0757|M.ulcerans_Agy99 GDGKAAYVQVKLAGNQGESLANESVEAVKTIVDSL---------QAPPGV
TH_3260|M.thermoresistible__bu PDGKSAYVQVKLAGNQGEALANESVETVREMIATVSEE------MAPEGV
Mb0458c|M.bovis_AF2122/97 NDGKAAYVQLSLAGNQGTPLANESVEAVRSIVEST---------PAPPGI
Rv0450c|M.tuberculosis_H37Rv NDGKAAYVQLSLAGNQGTPLANESVEAVRSIVEST---------PAPPGI
MLBr_02378|M.leprae_Br4923 NDGKAAYVQLSLAGNQGELLAQESIDAVRKIVVQT---------PAPPGI
Mvan_3833|M.vanbaalenii_PYR-1 TDGHAAYVALNLAGNMGETKSNESVAAVRDIVADSPP---------PPGV
Mflv_2705|M.gilvum_PYR-GCK SDGRAAYATLNLAGNMGETESNEAVAAVRDIVANSPP---------PPGV
MMAR_3174|M.marinum_M PDGKAAYLQLYLSGNIGDTLANESVGAVWAAVDARPP---------PPGV
MAB_2301|M.abscessus_ATCC_1997 TDGKATYVQVNLAGNMGETLSNESTEAARNIVKQLEADWTKDGNKLPDGL
** ::* : ** * ::*: :. : * *:
MAV_2510|M.avium_104 KAYVTGPAALSADQHTAGDRSLQLITAATFTVIIGMLLLVYRSVITVLLT
MSMEG_3496|M.smegmatis_MC2_155 KAYVTGPAALSADQHVASDRSVRVIEALTFAVIITMLLLVYRSIVTVILT
MUL_0757|M.ulcerans_Agy99 KVYVTGSAALVADQQLAGDRSLQLIEMVTFTVIIVMLLLVYRSIITAAIM
TH_3260|M.thermoresistible__bu QAFVTGGAAMSADQQEAGDSSLRVIEALTFLVITTMLLFVYRSVITVLIA
Mb0458c|M.bovis_AF2122/97 KAYVTGPSALAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSIITVVLL
Rv0450c|M.tuberculosis_H37Rv KAYVTGPSALAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSIITVVLL
MLBr_02378|M.leprae_Br4923 TAWVTGASALIADMHHSGDKSMIRITATSVIVILVTLLLVYRSFITVILL
Mvan_3833|M.vanbaalenii_PYR-1 QVHVTGPAALTADVNIAGESSMALILLVTFVVIIVLLLFFYRSITTVVLL
Mflv_2705|M.gilvum_PYR-GCK TVHVTGPAALIADVNIAGERSMALVLLVTFVVIIVLLLFFYRSISTVLLL
MMAR_3174|M.marinum_M KVYVTGPAALQADLIHSAERTVRTIKIATFTVIIVLMLFFFRSVPTVLVL
MAB_2301|M.abscessus_ATCC_1997 TVYVTGPGALQTDMNHAGDGSLQLITGLTFLVIVVMLLFFYRSIFTVIMV
. *** .*: :* :.: :: : :. ** :*:.:**. *. :
MAV_2510|M.avium_104 LVMVVLELSAARGMVAFLGYYKIIGLSTFATNLLVTLAIAAATDYAIFLI
MSMEG_3496|M.smegmatis_MC2_155 LVMVVLSLSAARGMIAFLGYHEIIGLSVFATNLLTTLAIAAATDYAIFLI
MUL_0757|M.ulcerans_Agy99 LTMVVLGLLATRGGVAFLGYHRIIGLSTFATNLLVVLAIAAATDYAIFLI
TH_3260|M.thermoresistible__bu LFMVLIGLLTTRGVVAFLGYHNIIGLSTFATSLLVTLAIAIAVDYAIFLI
Mb0458c|M.bovis_AF2122/97 LITVGVELTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFII
Rv0450c|M.tuberculosis_H37Rv LITVGVELTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFII
MLBr_02378|M.leprae_Br4923 LFTVGIESAVARGVVALLGHTGLIGLSTFAVNLLTSLAIAAGTDYGIFIT
Mvan_3833|M.vanbaalenii_PYR-1 LIMVGVQMSVARGVVAALGHFQVIGLSTFAVNLLISLAVAAGTDYAIFLV
Mflv_2705|M.gilvum_PYR-GCK LVVVGIQLLVARGVVAALAHVGVIGLSTYATNLLISLAVAAGTDYAIFLV
MMAR_3174|M.marinum_M LGVVGIQLSAATGVAAVIGYLGVVELSTFAVNLVVAMAIATGTDYAIFLI
MAB_2301|M.abscessus_ATCC_1997 FMLVGIQLSAARGVIAFLGNTEIIGLSTFAVNLLVMLSIAAGTDYAIFLI
: * : .: * * :. : *:.:*..*: :::* ..**.**:
MAV_2510|M.avium_104 GRYQEARAVGESREDAYYTMYKGTAHVVAGSGMTIAGATFCLHFTNLPYF
MSMEG_3496|M.smegmatis_MC2_155 GRYQEARSVGEDREQSYYTMFHSTAHVVLGSGMTIAGATLCLHFTRMPYF
MUL_0757|M.ulcerans_Agy99 GRYQEARGLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFTRLPYF
TH_3260|M.thermoresistible__bu GRYQEARSVGADRATAYHTMFGGTAHVILASGLTIAGATFCLSFTRLPYF
Mb0458c|M.bovis_AF2122/97 GRYQEARQAGEDKEAAYYTMYRGTAHVILGSGLTITGATFCLSFARMPYF
Rv0450c|M.tuberculosis_H37Rv GRYQEARQAGEDKEAAYYTMYRGTAHVILGSGLTIAGATFCLSFARMPYF
MLBr_02378|M.leprae_Br4923 GRYQEARQANENKEAAFYTMYRGTFHVILGSGLTISGATFCLSFARMPYF
Mvan_3833|M.vanbaalenii_PYR-1 GRYQEARASGADPEAAYYEMFGGTAHVVLGSGLTIAGAMYCLSFARMPYF
Mflv_2705|M.gilvum_PYR-GCK GRYQEARASGADHEEAYYEMFHGTAHVVLGSGLTIAGAMLCLSFTRMPYF
MMAR_3174|M.marinum_M GRYQEARAAGVDRESAYYEMWHGTAHVVLASGLTIAGAALCMSLTRMPYL
MAB_2301|M.abscessus_ATCC_1997 GRYQEARAMGADKEAAYYEMFHGTAHVILGSGMTIAGAMYCLSFTRMPYF
******* . . ::: *: .* **: .**:**:** *: ::.:**:
MAV_2510|M.avium_104 QTLGIPLAIGMVVVVAAALTLGPAVISVASRFRQTLEPRRTQRIRGWRKV
MSMEG_3496|M.smegmatis_MC2_155 QSLGIPLAIGMSVVVLASLTMGAAIISVASRFGKTFEPKRAMRTRGWRKL
MUL_0757|M.ulcerans_Agy99 QTLGVPLAIGMVIVVATALTLGPALIAVMSRFGKLLEPKRMARVRGWRKI
TH_3260|M.thermoresistible__bu QSLGPPLAIGMIVLIVTSLTMGPAIITVATRFG-LLEPKRAARVRFWRKV
Mb0458c|M.bovis_AF2122/97 QTLGIPCAVGMLVAVAVALTLGPAVLHVGSRFG-LFDPKRLLKVRGWRRV
Rv0450c|M.tuberculosis_H37Rv QTLGIPCAVGMLVAVAVALTLGPAVLHVGSRFG-LFDPKRLLKVRGWRRV
MLBr_02378|M.leprae_Br4923 QTLGVPCAVGMLIAVAVALTLGPAVLTVGSRFG-LFEPKRLIKVRGWRRI
Mvan_3833|M.vanbaalenii_PYR-1 QSMGVPCAVGILAGVAVALTLGPAIVTVGSRFG-LLEPKRAMRIRAWRRV
Mflv_2705|M.gilvum_PYR-GCK QSMGIPCAVGIAAGVAVALTLGPAIVTVGSRFN-LLEPKRAMRIRAWRRI
MMAR_3174|M.marinum_M QSLGVPTAVAMLVALSVALTLGPAAVTVASRFG-LLEPKRAIRIRFWRRI
MAB_2301|M.abscessus_ATCC_1997 QTLGVPCSVGLLVGVLVSLTLGPALITIGSRFG-LFEPKRAMRIRSWRKI
*::* * ::.: : .:**:*.* : : :** ::*:* : * **::
MAV_2510|M.avium_104 GTVVVRWPGPILVLTIGVALVGLLTLPGYRTNYNDRNYLPTDLPANEGYA
MSMEG_3496|M.smegmatis_MC2_155 GAAVVRWPAPILVTTIALSVVGLLALPGYQTNYNDRRYLPQDLPANTGYA
MUL_0757|M.ulcerans_Agy99 GAAIVRWPGPILIGAVALALVGLLTLPGYKTNYNDRNYLPADLPANEGYS
TH_3260|M.thermoresistible__bu GASVVRWPGPIMVTTVAVTLVGLLALPGYRTNYNDRNYLPASFPSNAGYE
Mb0458c|M.bovis_AF2122/97 GTVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPANQGYA
Rv0450c|M.tuberculosis_H37Rv GTVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPANQGYA
MLBr_02378|M.leprae_Br4923 GTVVVRWPLPILITTCAIAMVGLLALPGYRTNYKDRAYLPASIPANQGFA
Mvan_3833|M.vanbaalenii_PYR-1 GATVVRWPGPILVASLALALIGLAALPGYKTSYDDTRYIPESIPANAGLQ
Mflv_2705|M.gilvum_PYR-GCK GTMVVRWPGPILVASLALALVGLAALPGYQTSYDDTRYVPESIPANAGLQ
MMAR_3174|M.marinum_M GTAVVRWPAPILLASLAAALVGLIALPFYQPSYNDRRYIPGDIEANAGYA
MAB_2301|M.abscessus_ATCC_1997 GTTIVRWPGPVLAAAMAIAIIGLAALPGYRTSYDDKKYIPKDIPANAGFQ
*: :**** *:: : . :::** :** *:..*.* *:* : :* *
MAV_2510|M.avium_104 AADRHFSQARMNPEVLMIESDHDLRNSADFLVIDKIAKTVFRVPGIGRVQ
MSMEG_3496|M.smegmatis_MC2_155 AADRHFSQARMNPELLMIESDHDLRNSADFLVVDRIAKRVFQVPGISRVQ
MUL_0757|M.ulcerans_Agy99 AAERHFSQARMNPEVLMVESDHDMRNSSDFLVINKIAKAIFGVEGISRVQ
TH_3260|M.thermoresistible__bu AAERHFDPARLNPELLLIESDHDLRNPADFLVIEKIAKAVFQVEGISRVQ
Mb0458c|M.bovis_AF2122/97 AADRHFSQARMKPEILMIESDHDMRNPADFLVLDKLAKGIFRVPGISRVQ
Rv0450c|M.tuberculosis_H37Rv AADRHFSQARMKPEILMIESDHDMRNPADFLVLDKLAKGIFRVPGISRVQ
MLBr_02378|M.leprae_Br4923 AADRHFPQARMKPEILMIESDHDMRNPADFLILDKLARGIFRVPGISRVQ
Mvan_3833|M.vanbaalenii_PYR-1 AATKYFSLSRMSPEVLIVEADRDLRNSSDFLILDRLAKRVFNVEGVARVQ
Mflv_2705|M.gilvum_PYR-GCK AATQHFTLSRMSPEILIVEADRDLRNPADFLVLDRLAKRVFAVEGVARVQ
MMAR_3174|M.marinum_M AAEQHFSAARMNPEVLLVEADHDLRNPADFLVIDKLAKAIFRVPGVARVQ
MAB_2301|M.abscessus_ATCC_1997 AADRHFSQARMNPEMLLIESDHDMRNSADFLVIDKIAKAVFRVPGIARVQ
** ::* :*:.**:*::*:*:*:**.:***:::::*: :* * *:.***
MAV_2510|M.avium_104 AITRPQGTPIEHTSIPFQISMQGVTQQMNQKYQQDQMADMLHQADMMQTT
MSMEG_3496|M.smegmatis_MC2_155 AITRPQGTPIEHTSIPFQISMSGTTQMMNMKYMQDRMADMLVMADEMQKS
MUL_0757|M.ulcerans_Agy99 AITRPDGKPIEHTSIPFLISMQGTSQKLTEKYNQDLTTSMLQQVNDIQTN
TH_3260|M.thermoresistible__bu GITRPEGTPIEHSSIPFMISQQGTLQILNQQYMQDRMADMLVQADEMQLM
Mb0458c|M.bovis_AF2122/97 AITRPEGTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQADEMATT
Rv0450c|M.tuberculosis_H37Rv AITRPEGTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQADEMATT
MLBr_02378|M.leprae_Br4923 AITRPDGTAMDHTSIPFQISMQNAGQVQTMKYQKDRMNDLLRQAENMAET
Mvan_3833|M.vanbaalenii_PYR-1 APSRPDGAPIAHTSIPFLISMQGVGQQQNMKLMKDRIADMRVQADDIGET
Mflv_2705|M.gilvum_PYR-GCK APSRPDGSPIAKTSIPFLISMQGVGQQQNMKLMQDRMDDMRTQADNLGKT
MMAR_3174|M.marinum_M AITRPDGAPIQHTSIPFMMSMQGVGLQQNMKLMFDRIDDMKAQAESLGNT
MAB_2301|M.abscessus_ATCC_1997 AITRPQGTPIEHSSIPFLISMQSVGQRQNMKLMKDRMADMKVQADKMGEN
. :**:* .: ::**** :* ... . : * .: .: :
MAV_2510|M.avium_104 IDSMEKMQSITVQMSNDMHVMVQKMHDMTIDINDLRNKMADFEDFFRPMR
MSMEG_3496|M.smegmatis_MC2_155 VDTMEEMLKITREMSDTTHSMVGKMHGMVEDIKELRDHIADFDDFLRPIR
MUL_0757|M.ulcerans_Agy99 IDQMERMHDLTQQMADVTHQMVIQMKGMVVDVEELRNHIADFDDFFRPIR
TH_3260|M.thermoresistible__bu IDTMDKMIALMEEMVETTDNMVRDMDEMAAHVAEMRDSISEFDDFFRPIR
Mb0458c|M.bovis_AF2122/97 IAVLTRMHSLMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDFWRPIR
Rv0450c|M.tuberculosis_H37Rv IAVLTRMHSLMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDFWRPIR
MLBr_02378|M.leprae_Br4923 IASMRRMHQLMALLTENTHHILNDTVEMQKTTSKLRDEIANFDDFWRPIR
Mvan_3833|M.vanbaalenii_PYR-1 IATMKTMYGLMTKFSNITTVMIDDMTEMRDTVHQIRDMVATFDDQFRPIR
Mflv_2705|M.gilvum_PYR-GCK LGTMRTMYGLMTRLSEVTTVMIDDFTEMQQTVHQIRDMVANFDDQFRPVR
MMAR_3174|M.marinum_M VAIMKRMQASMSRMAGVGDGLVVDMDDMQTAVRDARDSLADFEDFFRPIR
MAB_2301|M.abscessus_ATCC_1997 VVIMKRTLANMTTMAGITHSLVGDMHTLQGTIHEMRDSISNFDDWFRPIR
: : : :: . : . *: :: *:* **:*
MAV_2510|M.avium_104 SYFYWEKHCYDIPVCWSLRSVFDALDGIDTMTDDIQSLLPIMDHLDTLMP
MSMEG_3496|M.smegmatis_MC2_155 NYFYWEPHCDSIPVCQSIRSIFDTLDGIDVMTDDIQRLMPDMDRLDELMP
MUL_0757|M.ulcerans_Agy99 SYFYWEKHCFDIPVCWSLRSVFDTLDGVDLMTEDINNLLPLMERLDTLMP
TH_3260|M.thermoresistible__bu NYFYWEPHCYNIPVCWAMRSVFDTLDGINTMTDDIQNMLPHMHRLNDLMP
Mb0458c|M.bovis_AF2122/97 SYFYWEKHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREMDRLMP
Rv0450c|M.tuberculosis_H37Rv SYFYWEKHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREMDRLMP
MLBr_02378|M.leprae_Br4923 SYFYWERHCFNIPICWSFRSIFDALDGVDQIDERLNSIVGDIKNMDLLMP
Mvan_3833|M.vanbaalenii_PYR-1 NYFYWEPHCYNIPLCWSFRSLFDSMDGISVMTDTFDKAVANMDEMKALLP
Mflv_2705|M.gilvum_PYR-GCK NYFYWEPHCYNIPLCWSFRSLFDSMDGISTMTESFDKALVNMETMRSLLP
MMAR_3174|M.marinum_M NYFHWEPHCFDIPVCWALRSVSDSVDGIDAMTDQMDRMIKGMTDLNALIP
MAB_2301|M.abscessus_ATCC_1997 NYLYWEKHCFDIPMCWAMRSIFDTLDKIDEMTETMDGMVVNMERMDTLMP
.*::** ** .**:* ::**: *::* :. : : : : : : *:*
MAV_2510|M.avium_104 QMVALMPSMIENMKAMKTTMLTMYSTQKGLQDQQNEAQKNSNAMGKAFDA
MSMEG_3496|M.smegmatis_MC2_155 QMLTIMPPMIESMKTMKTMMLTTQATMGGLQDQMEAAMENQTAMGQAFDA
MUL_0757|M.ulcerans_Agy99 QMTAMMPEMIQTMKSMKAQMLSMHSTQQGLQDQMAAMQEDSSAMGEAFDS
TH_3260|M.thermoresistible__bu QMLTLLPTTVATMKTMRSMLLTMQATNAGLQDQMAEMQENANAMGEAFDQ
Mb0458c|M.bovis_AF2122/97 QMVAQIPPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMGKAFDA
Rv0450c|M.tuberculosis_H37Rv QMVAQIPPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMGKAFDA
MLBr_02378|M.leprae_Br4923 QMLEQFPPMIESMESMRTIMLTMHSTMSGIFDQMNELSDNANTMGKAFDT
Mvan_3833|M.vanbaalenii_PYR-1 QMLATFPPMIETMESMRQMMLTTYATMGGFYDQMDELTRDSTEMGKAFDA
Mflv_2705|M.gilvum_PYR-GCK QMLATFPPMIETMESMRQMMLTTYATMGGFYDQMDELTQDSTEMGKAFDE
MMAR_3174|M.marinum_M EMIAQFPPMIATMESMQQMMLTMHSTMSGMYRQMDELSHGAAEMGKAFDA
MAB_2301|M.abscessus_ATCC_1997 KMVSDMSAMIPIMEDMQRMMLTQHSTMSGFYNQMDEMSQNSTAMGKAFDA
:* :. : *: *: :*: :* *: * . **:***
MAV_2510|M.avium_104 SKNDDSFYLPPETFNNKEFKKGMKNFISPDGHAVRFIISHDGDPMTQEGI
MSMEG_3496|M.smegmatis_MC2_155 SKNDDSFYLPPETFENPDFKRGMKMFLSPDGHAVRFIISHEGDPMSPEGI
MUL_0757|M.ulcerans_Agy99 SRNDDSFYLPPEVFNNPDFKRGLEQFLSPDGHAVRFIISHEGDPMSQAGI
TH_3260|M.thermoresistible__bu ARNDDSFYLPPEAFDNPDFQRGLEQFLSPDGHAVRFIISHQGDPMTPEGL
Mb0458c|M.bovis_AF2122/97 AKNDDSFYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQSPEGI
Rv0450c|M.tuberculosis_H37Rv AKNDDSFYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQSPEGI
MLBr_02378|M.leprae_Br4923 AKNDDSFYLPPEVFKNTDFKRAMKSFLSSDGHAARFIILHRGDPASVAGI
Mvan_3833|M.vanbaalenii_PYR-1 AKNDDSFYLPPEVFENEDFKRAMESFFSPDGKTVRMLIAHRGNPTTDEAL
Mflv_2705|M.gilvum_PYR-GCK AKNDDSFYLPPEVFENEDFKRAMESFFSPDGKTVRMLVSHRGDPTTPEAL
MMAR_3174|M.marinum_M ARNDDSFYLPSEVFDNPDFRRAMDLFISPDGKSLRMIISHRGDPASAEGI
MAB_2301|M.abscessus_ATCC_1997 AKNDDSFYLPPEIFDNADFKRGMKSFLSPDGKAVRMIISHRGDPATPEGL
::********.* *.* :*::.:. *:*.**:: *::: * *:* : .:
MAV_2510|M.avium_104 SHIGAIKKAAYEALKGTPLEGSKIYLAGTASIYKDLSDGNNYDLLIAGIS
MSMEG_3496|M.smegmatis_MC2_155 KHIDAIKQAAKEAIKGTPLEGSKIYLGGTAATFKDLQEGANYDLIIAGIA
MUL_0757|M.ulcerans_Agy99 NHIDKIKTAAKEAIKGTPLEGSTIYLGGTVAMFKDLSDGNTFDLMIAGIS
TH_3260|M.thermoresistible__bu AKIEPIKKAAVEAIKGTPLEGSRVYLGGTAAVFKDMSDGTKYDLIIAAIA
Mb0458c|M.bovis_AF2122/97 KSIDAIRTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAIS
Rv0450c|M.tuberculosis_H37Rv KSIDAIRTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAIS
MLBr_02378|M.leprae_Br4923 ASINAIRTAAEEALKGTPLEDTKIYLAGTAAVFKDIDEGANWDLVIAGIS
Mvan_3833|M.vanbaalenii_PYR-1 QRVEPIKIAAIEALKGTPLENAQIQLGGTAATFKDMSDGSRYDLLIAVIS
Mflv_2705|M.gilvum_PYR-GCK ARVEPIKIAAIEALKGTPLENAQIQLGGTAATFKDMSDGSRYDMMIAILS
MMAR_3174|M.marinum_M SRVDPIKLAAIEALKGTPLENAKVSLGGTASVYHDLSEGTRYDLVIAVIA
MAB_2301|M.abscessus_ATCC_1997 SHVEPIKQAAIEAVKGTPLEDAKIELGGTAAVFKDMSDGAKYDLMIAGIS
: *: ** *::******.: : *.**.: ::*:.:* :*::** ::
MAV_2510|M.avium_104 SLCLIFIIMLIITRGVVASAVIVGTVLLSLGASFGLSVLIWQHLIGIELH
MSMEG_3496|M.smegmatis_MC2_155 ALCLIFIIMLIITRAVVASAVIVGTVVISLGASFGLSVLIWQHIIGLELH
MUL_0757|M.ulcerans_Agy99 ALCLIFIIMLIITRSVVAAAVIVGTVVLSLGASFGLSVLIWQHVLGIELH
TH_3260|M.thermoresistible__bu AVCLIFIIMLILTRAVVAAAVIVGTVTLSLAASFGVSVLIWQYIVGLEMH
Mb0458c|M.bovis_AF2122/97 SLCLIFIIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHILAIHLH
Rv0450c|M.tuberculosis_H37Rv SLCLIFIIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHILAIHLH
MLBr_02378|M.leprae_Br4923 SLCLIFIIMLIITRAFVAAAVIVGTVALSLGASFGLSVLLWQHILGIELH
Mvan_3833|M.vanbaalenii_PYR-1 ALCLVLMIMLVLTRSLVAALVIVGTVTLSLGASFGISILIWQHIVGIELH
Mflv_2705|M.gilvum_PYR-GCK ALCLVLVIMLVLTRSLVAAVVIVGTVALSLGASFGVSVLIWQHLLGVELH
MMAR_3174|M.marinum_M TVCLIFAIMLLITRSLVAAMVIVGTVLLSLGASVGLSVLLWQYIVGLPLQ
MAB_2301|M.abscessus_ATCC_1997 ALCLIFLIMLLITRSFVASLVIVGTVALSLGASFGLSVIIWQYILGIELH
::**:: ***::**..:*: ****** :**.**.*:*:::**:::.: ::
MAV_2510|M.avium_104 WMVLAMSVIILLAVGADYNLLLVARFKEEIHAGLNTGIIRSMGGTGSVVT
MSMEG_3496|M.smegmatis_MC2_155 WMVLAMAVIVLLAVGADYNLLLVSRIKEEIHAGLNTGIIRSMGGTGSVVT
MUL_0757|M.ulcerans_Agy99 WLVLAMAVIILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGSGSVVT
TH_3260|M.thermoresistible__bu WMVFPMALIILLAVGADYNLLVVARLREEIPAGLNTGMIRAMGGSGSVVT
Mb0458c|M.bovis_AF2122/97 WLVLAMSVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVVT
Rv0450c|M.tuberculosis_H37Rv WLVLAMSVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVVT
MLBr_02378|M.leprae_Br4923 YLVLAMSVIVLLAVGSDYNLLLVSRFKQEIQAGLKTGIIRSMGGTGKVVT
Mvan_3833|M.vanbaalenii_PYR-1 WMVLALSIIALIAVGSDYNLLLVSRFKEEIPAGIKTGIIRAIGGTGSVVT
Mflv_2705|M.gilvum_PYR-GCK WMVLVMSIIALIAVGSDYNLLLVSRFKEEIGAGIKTGIIRAIGGTGSVVS
MMAR_3174|M.marinum_M WMVMSMAVIILLAVGADYNLMMVARFKEEMPAGLKTGIIRAMGGAGSVVT
MAB_2301|M.abscessus_ATCC_1997 WLVMQMAIIVLLAVGSDYNLLLVSRLKEELHGGLKTGIIRSMGGTGSVVT
::*: :::* *:***:****::*:*:::*: .*::**:**::**:*.**:
MAV_2510|M.avium_104 SAGLVFAFTMMTMAVSELTVIGQVGTTIGLGLLFDTLIVRSLMTPSIAAL
MSMEG_3496|M.smegmatis_MC2_155 SAGLVFAFTMMSMAVSELAVIAQVGTTIGLGLLFDTLVIRSFMTPSIAAL
MUL_0757|M.ulcerans_Agy99 AAGLVFAFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTPSIAAL
TH_3260|M.thermoresistible__bu AAGLVFGLTMMVMVVSDLTVMGQVGTTIGLGLLFDTFVVRSFMMPSIATL
Mb0458c|M.bovis_AF2122/97 NAGLVFAVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAAL
Rv0450c|M.tuberculosis_H37Rv NAGLVFAVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAAL
MLBr_02378|M.leprae_Br4923 NAGLVFAFTMASMVVSDLRVIGQVGTTIGLGLLFDTLIVRSFMMPSIAAL
Mvan_3833|M.vanbaalenii_PYR-1 VAGVVFALTMASMVVSDLRVMAQVGTTIGLGLLFDTFIVRAFMMPAIATL
Mflv_2705|M.gilvum_PYR-GCK VAGVVFALTMASMVVSDLKVIAQVGTTIGLGLLFDTFIVRAFMMPSIATL
MMAR_3174|M.marinum_M AAGLVFAFTMTSMVVSDLRTIGQIGTFIGLGLLFDTLIVRSFMVPSIAAL
MAB_2301|M.abscessus_ATCC_1997 SAGLVFAFTMAVMVVSDLRIIGQVGTTIALGLLFDTLIVRSFMTPAVATL
**:**..** :.**:* :.*:** *.:******:::*::* *::*:*
MAV_2510|M.avium_104 LGKWFWWPQRVRQRPVPSPWPKPAAQEREVLADA----------------
MSMEG_3496|M.smegmatis_MC2_155 MGKWFWWPQRVRQRPLPAPWPQPVQRDPEDALNRV---------------
MUL_0757|M.ulcerans_Agy99 LGKWFWWPQVVRQRPAPQPWPTPAPTPPPATTSV----------------
TH_3260|M.thermoresistible__bu LGRWFWWPQFVRKRPVPQPWPSVPPRGPATTDRVSV--------------
Mb0458c|M.bovis_AF2122/97 LGRWFWWPLRVRSRPARTPTVPSETQPAGRPLAMSSDRLG----------
Rv0450c|M.tuberculosis_H37Rv LGRWFWWPLRVRSRPARTPTVPSETQPAGRPLAMSSDRLG----------
MLBr_02378|M.leprae_Br4923 LGRWFWWPQQGRTRPLLTVAAPVGLPPD-RSLVYSD--------------
Mvan_3833|M.vanbaalenii_PYR-1 LGRWFWWPLVVRSRPLRLP-------PRT---------------------
Mflv_2705|M.gilvum_PYR-GCK LGRWFWWPLVVRSRPLRPR-------PQQQALGVGGQQG-----------
MMAR_3174|M.marinum_M LGRWFWWPINVRTRPARAR-------PVRPQA------------------
MAB_2301|M.abscessus_ATCC_1997 LGRWFWWPLNVRTRPLPPPRTTVAADPTPPPVPVGPGHGDDPITTEFPRP
:*:***** * **
MAV_2510|M.avium_104 --
MSMEG_3496|M.smegmatis_MC2_155 --
MUL_0757|M.ulcerans_Agy99 --
TH_3260|M.thermoresistible__bu --
Mb0458c|M.bovis_AF2122/97 --
Rv0450c|M.tuberculosis_H37Rv --
MLBr_02378|M.leprae_Br4923 --
Mvan_3833|M.vanbaalenii_PYR-1 --
Mflv_2705|M.gilvum_PYR-GCK --
MMAR_3174|M.marinum_M --
MAB_2301|M.abscessus_ATCC_1997 SV