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STPDAPTEAIPSAHGKYTNHGGIAKLIRTLAVPIILVWVALIAVLNTIVPQLEEVGEMRSVSMSPDDAPS MIAMKRVGEVFEEFKSNSSVMIVLEGEQPLGDEAHKYYDEIVDKLEADKTHIEHVQDFWGDPLTASGAQS SDGLASYVQVYTAGNQGEALANESVKAVQDIVDSVQAPPGVTAYVTGPAAMSADQQIAGDRSMRMIEALT FTVIIIMLLMVYRSIITVILSLVMVVFSLAAARGVIAFLGYYEIIGLSTFATNLLVTLAIAAATDYAIFL IGRYQEARSVGESREQAYYTMFHSTAHVVLGSGMTIAGATLCLHFTRMPYFQSLGIPLAIGMTVVVLTAL AVGPAIITVASRFGKTLEPKRAMRTRGWRKVGAAVVRWPGPILVAAVGLSMIGLLALPGYRTNYNDRDYQ PADLPANSGYAAADRHFSQARMNPELLMIESDHDLRNSADFLVIERIAKRVVGVPGVSRVQAITRPQGTP IEHTSIPFTISMQGTTQTMNQKYMQDRMADMLVQADQMQVTVDTMTKMIALMEQMRDTMNSMVGKMHGMV DDIKELRDNISDFDDFFRPIRNYLYWEPHCYNIPMCYSLRSIFDTMDGIDTMTADFEQIVPDMDRMNALI PVMIANMEPMITTMKTMKTMMLTMQATNAGLQDQMAAMQENSTAMGEAFDKAKNDDSFYLPPETFDNPDF KRGMKMFLSPDGHAVRFIISHEGDPMSPEGIQKIDDIKLAAKEAIKGTPLEGSKIYLGGTAATFKDMQEG ANYDLIIAGIAALCLIFIIMLIITRAVVASAVIVGTVVISLGSAFGLSVLIWQHLVGLELHWMVLAMAVI VLLAVGADYNLLLVSRIKEEIHAGLDTGMIRAMGGSGSVVTAAGLVFAFTMMSMAVSELAIIGQVGTTIG LGLLFDTLVIRSFMTPSIAALLGKWFWWPQMVRRRPKPSPWPKPIQREPADAVN*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_0225 | - | - | 100% (965) | MmpL4 protein |
M. smegmatis MC2 155 | MSMEG_3496 | - | 0.0 | 83.45% (967) | MmpL4 protein |
M. smegmatis MC2 155 | MSMEG_4383 | - | 0.0 | 72.43% (943) | MmpL5 protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0695c | mmpL5 | 0.0 | 71.16% (950) | transmembrane transport protein MmpL5 |
M. gilvum PYR-GCK | Mflv_3435 | - | 0.0 | 73.97% (968) | transport protein |
M. tuberculosis H37Rv | Rv0676c | mmpL5 | 0.0 | 71.05% (950) | transmembrane transport protein MmpL5 |
M. leprae Br4923 | MLBr_02378 | - | 0.0 | 61.69% (924) | hypothetical protein MLBr_02378 |
M. abscessus ATCC 19977 | MAB_4382c | - | 0.0 | 64.49% (966) | putative membrane protein, MmpL |
M. marinum M | MMAR_1005 | mmpL5 | 0.0 | 70.96% (954) | transmembrane transport protein, MmpL5 |
M. avium 104 | MAV_2510 | - | 0.0 | 73.51% (955) | MmpL4 protein |
M. thermoresistible (build 8) | TH_3260 | - | 0.0 | 69.81% (964) | PUTATIVE MmpL4 protein |
M. ulcerans Agy99 | MUL_0757 | mmpL5 | 0.0 | 70.59% (959) | transmembrane transport protein, MmpL5 |
M. vanbaalenii PYR-1 | Mvan_3189 | - | 0.0 | 73.24% (968) | transport protein |
CLUSTAL 2.0.9 multiple sequence alignment MSMEG_0225|M.smegmatis_MC2_155 --MSTP-DAPTEAIPSAHG--KYTNHGG--IAKLIRTLAVPIILVWVALI TH_3260|M.thermoresistible__bu -MTANPGHVRTDEAPTDRLDIKVSTHGPSFISTWIRRLSLPIIVGWIALI Mflv_3435|M.gilvum_PYR-GCK -MSAPVSDARTDEFPAAHG-----PHRS-FIPRMIRLFAVPIILGWIALI Mvan_3189|M.vanbaalenii_PYR-1 -MSAPVSDARTDEFPAARQ-----PHRP-FIPRMIRLFAVPIILGWIALI Mb0695c|M.bovis_AF2122/97 -MIVQRTAAPTGSVPPDRH-----AARP-FIPRMIRTFAVPIILGWLVTI Rv0676c|M.tuberculosis_H37Rv -MIVQRTAAPTGSVPPDRH-----AARP-FIPRMIRTFAVPIILGWLVTI MMAR_1005|M.marinum_M -MTATTTDTPTDVVPPAEH-----PPRP-FIPRMIRTFAVPLILGWVLLI MUL_0757|M.ulcerans_Agy99 -MTATTTDTPTDVVPPAEH-----PPRP-FIPRMIRTFAVPLILGWVLLI MAV_2510|M.avium_104 -MSTTFDDTRTDAIPVVKEP----VREK--IPRFIRAFAVPIIIGWIALI MAB_4382c|M.abscessus_ATCC_199 -MSKPMNDPTTDAFPAARH-----AARP-WLPRMIRVLAVPIVLGWIAVT MLBr_02378|M.leprae_Br4923 MTVKCANDLDTHTKP------------P-FVARMIHRFAVPIILVWLAIA * * :. *: :::*::: *: MSMEG_0225|M.smegmatis_MC2_155 AVLNTIVPQLEEVGEMRSVSMSPDDAPSMIAMKRVGEVFEEFKSNSSVMI TH_3260|M.thermoresistible__bu ALLNITVPQLEVVGEMRAVSMSPDEAPSMVAMKRVGELFDEGSSDSQVMI Mflv_3435|M.gilvum_PYR-GCK VVVNVTVPQLETVGEAQAVSMSPNDAPSMISMKKVGELFEEGDSDSSVMI Mvan_3189|M.vanbaalenii_PYR-1 VILNVTVPQLEAVGEARAVSMSPNEAPSLISMKKVGELFREGDSDSSVMI Mb0695c|M.bovis_AF2122/97 AVLNVTVPQLETVGQIQAVSMSPDAAPSMISMKHIGKVFEEGDSDSAAMI Rv0676c|M.tuberculosis_H37Rv AVLNVTVPQLETVGQIQAVSMSPDAAPSMISMKHIGKVFEEGDSDSAAMI MMAR_1005|M.marinum_M AVLNSVVPQLEVVGQMQAVSMSPDAAPSMISMKHIGKVFREGDSDSAAMI MUL_0757|M.ulcerans_Agy99 AVLNSVVPQLEVVGQMQAVSMSPDAAPSMISMKHIGKVFREGDSDSAAMI MAV_2510|M.avium_104 AVLNVVVPQLDEVGKMRSVEMTPDDAQSVVATKRMGAVFNEYKSNSSVMI MAB_4382c|M.abscessus_ATCC_199 IALNTVVPQLEEVGHMRAVSMSPNDAPAMIATKRVGEVFEEFKTSSSVMI MLBr_02378|M.leprae_Br4923 VTVSVFIPSLEDVGQERSVSLSPKDAPSYIAMQKMGQVFNEGNSDSVIMI :. :*.*: **. ::*.::*. * : :: :::* :* * .:.* ** MSMEG_0225|M.smegmatis_MC2_155 VLEGEQPLGDEAHKYYDEIVDKLEADKTHIEHVQDFWGDPLTASGAQSSD TH_3260|M.thermoresistible__bu VLEGEEPLGADARAFYDELVKRLEADDAHVENVQDLWSDPLTATGVQSPD Mflv_3435|M.gilvum_PYR-GCK VFEGDQPLGDEAHAWYDELVDRLEADTAHVQSVQDFWSDPLTASGSQSND Mvan_3189|M.vanbaalenii_PYR-1 VFEGDQPLGDEAHAWYDELVERLRADTKHVQSVQDFWSDPLTASGSQSND Mb0695c|M.bovis_AF2122/97 VLEGQRPLGDAAHAFYDQMIGRLQADTTHVQSLQDFWGDPLTATGAQSSD Rv0676c|M.tuberculosis_H37Rv VLEGQRPLGDAAHAFYDQMIGRLQADTTHVQSLQDFWGDPLTATGAQSSD MMAR_1005|M.marinum_M VLEGQEPLGAAAHKFYDKMITKLRADTKHVQSVQDFWGDPLTATGAQSGD MUL_0757|M.ulcerans_Agy99 VLEGQEPLGAAAHKFYDKMITKLRADTKHVQSVQDFWGDPLTATGAQSGD MAV_2510|M.avium_104 VLEGQQPLGADAHAYYDEIVRRLNADTKHVEHVQDMWSDPLTGAGAQSND MAB_4382c|M.abscessus_ATCC_199 VLEGEQSLGADAHRFYDQMVRDLRADTTHVQHVQDFWADALTAAAAQSSD MLBr_02378|M.leprae_Br4923 VLEGDKPLGDDAHRFYDGLIRKLRAD-KHVQSVQDFWGDPLTAPGAQSND *:**:..** *: :** :: *.** *:: :**:*.*.**... ** * MSMEG_0225|M.smegmatis_MC2_155 GLASYVQVYTAGNQGEALANESVKAVQDIVDSV---QAPPGVTAYVTGPA TH_3260|M.thermoresistible__bu GKSAYVQVKLAGNQGEALANESVETVREMIATVSEEMAPEGVQAFVTGGA Mflv_3435|M.gilvum_PYR-GCK GKAAYVQVKLSGNQGEALANESVKAVQQTVSSLE---PPPGVRAFVTGPA Mvan_3189|M.vanbaalenii_PYR-1 GKAAYVQVKLAGNQGESLANESVQAAQEIVRSLE---PPPGVRAFVTGPA Mb0695c|M.bovis_AF2122/97 GKAAYVQVKLAGNQGESLANESVEAVKTIVERLA---PPPGVKVYVTGSA Rv0676c|M.tuberculosis_H37Rv GKAAYVQVKLAGNQGESLANESVEAVKTIVERLA---PPPGVKVYVTGSA MMAR_1005|M.marinum_M GKAAYVQVKLAGNQGESLANESVEAVKTIVDSLQ---APPGVKVYVTGSA MUL_0757|M.ulcerans_Agy99 GKAAYVQVKLAGNQGESLANESVEAVKTIVDSLQ---APPGVKVYVTGSA MAV_2510|M.avium_104 GKASYVQVYLAGNQGEALANESVESVQNIVKSVQ---APNGVKAYVTGPA MAB_4382c|M.abscessus_ATCC_199 GKAAYVQVYIAGDQGEALANESVEAVRHITAAVP---PSPGVRVYVTGPA MLBr_02378|M.leprae_Br4923 GKAAYVQLSLAGNQGELLAQESIDAVRKIVVQTP---APPGITAWVTGAS * ::***: :*:*** **:**:.:.: .. *: .:*** : MSMEG_0225|M.smegmatis_MC2_155 AMSADQQIAGDRSMRMIEALTFTVIIIMLLMVYRSIITVILSLVMVVFSL TH_3260|M.thermoresistible__bu AMSADQQEAGDSSLRVIEALTFLVITTMLLFVYRSVITVLIALFMVLIGL Mflv_3435|M.gilvum_PYR-GCK ALAADQHIAGDRSMRLIEAATFTVIIVMLLLVYRSIVTVLITLVMVVMSL Mvan_3189|M.vanbaalenii_PYR-1 ALAADQHIASDRSVRVIELVTFAVIIVMLLLVYRSIVTVLLTLVMVVLSL Mb0695c|M.bovis_AF2122/97 ALVADQQQAGDRSLQVIEAVTFTVIIVMLLLVYRSIITSAIMLTMVVLGL Rv0676c|M.tuberculosis_H37Rv ALVADQQQAGDRSLQVIEAVTFTVIIVMLLLVYRSIITSAIMLTMVVLGL MMAR_1005|M.marinum_M ALVADQQLAGDRSLQLIEMVTFTVIIVMLLLVYRSIITAAIMLTMVVLGL MUL_0757|M.ulcerans_Agy99 ALVADQQLAGDRSLQLIEMVTFTVIIVMLLLVYRSIITAAIMLTMVVLGL MAV_2510|M.avium_104 ALSADQHTAGDRSLQLITAATFTVIIGMLLLVYRSVITVLLTLVMVVLEL MAB_4382c|M.abscessus_ATCC_199 TTSADQEIVANDSMELIELVTFGVIMVMLLLVYRSVITMVIVVAMVMLEL MLBr_02378|M.leprae_Br4923 ALIADMHHSGDKSMIRITATSVIVILVTLLLVYRSFITVILLLFTVGIES : ** . .: *: * :. ** **:****.:* : : * : MSMEG_0225|M.smegmatis_MC2_155 AAARGVIAFLGYYEIIGLSTFATNLLVTLAIAAATDYAIFLIGRYQEARS TH_3260|M.thermoresistible__bu LTTRGVVAFLGYHNIIGLSTFATSLLVTLAIAIAVDYAIFLIGRYQEARS Mflv_3435|M.gilvum_PYR-GCK ATARGVVAFLGHHEIIGLSTFATNLLVTLAIAAATDYAIFLIGRYQEART Mvan_3189|M.vanbaalenii_PYR-1 ATARGVVAFLGWHEIIGLSLFATNLLVTLAIAAATDYAIFLIGRYQEART Mb0695c|M.bovis_AF2122/97 LATRGGVAFLGFHRIIGLSTFATNLLVVLAIAAATDYAIFLIGRYQEARG Rv0676c|M.tuberculosis_H37Rv LATRGGVAFLGFHRIIGLSTFATNLLVVLAIAAATDYAIFLIGRYQEARG MMAR_1005|M.marinum_M LATRGGVAFLGYHRIIGLSTFATNLLVVLAIAAATDYAIFLIGRYQEARG MUL_0757|M.ulcerans_Agy99 LATRGGVAFLGYHRIIGLSTFATNLLVVLAIAAATDYAIFLIGRYQEARG MAV_2510|M.avium_104 SAARGMVAFLGYYKIIGLSTFATNLLVTLAIAAATDYAIFLIGRYQEARA MAB_4382c|M.abscessus_ATCC_199 ASARGLVALLSYHNAFGLTSFATSLVVTLAIAAATDYAIFLIGRYQEARR MLBr_02378|M.leprae_Br4923 AVARGVVALLGHTGLIGLSTFAVNLLTSLAIAAGTDYGIFITGRYQEARQ :** :*:*. :**: **..*:. **** ..**.**: ******* MSMEG_0225|M.smegmatis_MC2_155 VGESREQAYYTMFHSTAHVVLGSGMTIAGATLCLHFTRMPYFQSLGIPLA TH_3260|M.thermoresistible__bu VGADRATAYHTMFGGTAHVILASGLTIAGATFCLSFTRLPYFQSLGPPLA Mflv_3435|M.gilvum_PYR-GCK AGEDKETAYYTMFHGTAHVVLGSGLTIAGATFCLSFTRLPYFQTMGVPLA Mvan_3189|M.vanbaalenii_PYR-1 NGEDKESAYYTMFHGTAHVVLGSGLTIAGATYCLSFTRLPYFQTLGVPLA Mb0695c|M.bovis_AF2122/97 LGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFTRLPYFQTLGVPLA Rv0676c|M.tuberculosis_H37Rv LGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFTRLPYFQTLGVPLA MMAR_1005|M.marinum_M LGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFTRLPYFQTLGVPLA MUL_0757|M.ulcerans_Agy99 LGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFTRLPYFQTLGVPLA MAV_2510|M.avium_104 VGESREDAYYTMYKGTAHVVAGSGMTIAGATFCLHFTNLPYFQTLGIPLA MAB_4382c|M.abscessus_ATCC_199 AGEDRESAYYTMFHGTAHVVLASGLTIAGATFCLHFTRLPYFKTTGIPLS MLBr_02378|M.leprae_Br4923 ANENKEAAFYTMYRGTFHVILGSGLTISGATFCLSFARMPYFQTLGVPCA . .: *::**: .* **: .**:**:*** ** *:.:***:: * * : MSMEG_0225|M.smegmatis_MC2_155 IGMTVVVLTALAVGPAIITVASRFGKTLEPKRAMRTRGWRKVGAAVVRWP TH_3260|M.thermoresistible__bu IGMIVLIVTSLTMGPAIITVATRFG-LLEPKRAARVRFWRKVGASVVRWP Mflv_3435|M.gilvum_PYR-GCK IGMFVVVMAGVVLMVACISVATRFGKLLEPKRAMRIRGWRKIGAAIVRWP Mvan_3189|M.vanbaalenii_PYR-1 IGMFVVVMAGVILMVAMISVATRFGKLLEPKRAMRIRGWRKIGAAVVRWP Mb0695c|M.bovis_AF2122/97 IGMVIVVAAALTLGPAIIAVTSRFGKLLEPKRMARVRGWRKVGAAIVRWP Rv0676c|M.tuberculosis_H37Rv IGMVIVVAAALTLGPAIIAVTSRFGKLLEPKRMARVRGWRKVGAAIVRWP MMAR_1005|M.marinum_M IGMVIVVATALTLGPALIAVMSRFGKLLEPKRMARVRGWRKIGAAIVRWP MUL_0757|M.ulcerans_Agy99 IGMVIVVATALTLGPALIAVMSRFGKLLEPKRMARVRGWRKIGAAIVRWP MAV_2510|M.avium_104 IGMVVVVAAALTLGPAVISVASRFRQTLEPRRTQRIRGWRKVGTVVVRWP MAB_4382c|M.abscessus_ATCC_199 IGMAIVVAMALTLGPALISVASRFGNVLEPKGAGKARGWRRVGAATVRWP MLBr_02378|M.leprae_Br4923 VGMLIAVAVALTLGPAVLTVGSRFG-LFEPKRLIKVRGWRRIGTVVVRWP :** : : .: : * ::* :** :**: : * **::*: **** MSMEG_0225|M.smegmatis_MC2_155 GPILVAAVGLSMIGLLALPGYRTNYNDRDYQPADLPANSGYAAADRHFSQ TH_3260|M.thermoresistible__bu GPIMVTTVAVTLVGLLALPGYRTNYNDRNYLPASFPSNAGYEAAERHFDP Mflv_3435|M.gilvum_PYR-GCK GPILVATMAITLVGLLALPGYKTNYNDRDYLPADLPANQGYAVADEHFDQ Mvan_3189|M.vanbaalenii_PYR-1 GPILVATLAITLVGLLALPGYKTNYNDRTYLPADLPANEGYAVADRHFDQ Mb0695c|M.bovis_AF2122/97 GPILVGAVALALVGLLTLPGYRTNYNDRNYLPADLPANEGYAAAERHFSQ Rv0676c|M.tuberculosis_H37Rv GPILVGAVALALVGLLTLPGYRTNYNDRNYLPADLPANEGYAAAERHFSQ MMAR_1005|M.marinum_M GPILIGAVALALVGLLTLPGYKTNYNDRNYLPADLPANEGYSAAERHFSQ MUL_0757|M.ulcerans_Agy99 GPILIGAVALALVGLLTLPGYKTNYNDRNYLPADLPANEGYSAAERHFSQ MAV_2510|M.avium_104 GPILVLTIGVALVGLLTLPGYRTNYNDRNYLPTDLPANEGYAAADRHFSQ MAB_4382c|M.abscessus_ATCC_199 GAILVAAVTMALVGLLTLPGYHTTYNDRIYLPGQVPANVGYAAADRHFSK MLBr_02378|M.leprae_Br4923 LPILITTCAIAMVGLLALPGYRTNYKDRAYLPASIPANQGFAAADRHFPQ .*:: : ::::***:****:*.*:** * * ..*:* *: .*:.** MSMEG_0225|M.smegmatis_MC2_155 ARMNPELLMIESDHDLRNSADFLVIERIAKRVVGVPGVSRVQAITRPQGT TH_3260|M.thermoresistible__bu ARLNPELLLIESDHDLRNPADFLVIEKIAKAVFQVEGISRVQGITRPEGT Mflv_3435|M.gilvum_PYR-GCK ARMNPELLMIESDHDLRNSADFLVIDKIAKALFRVEGIARVQAITRPDGK Mvan_3189|M.vanbaalenii_PYR-1 ARMNPELLMIESDHDLRNSADFLVIDKIAKAIFKVEGIARVQAITRPDGK Mb0695c|M.bovis_AF2122/97 ARMNPEVLMVESDHDMRNSADFLVINKIAKAIFAVEGISRVQAITRPDGK Rv0676c|M.tuberculosis_H37Rv ARMNPEVLMVESDHDMRNSADFLVINKIAKAIFAVEGISRVQAITRPDGK MMAR_1005|M.marinum_M ARMNPEVLMVESDHDMRNSSDFLVINKIAKAIFGVEGISRVQAITRPDGK MUL_0757|M.ulcerans_Agy99 ARMNPEVLMVESDHDMRNSSDFLVINKIAKAIFGVEGISRVQAITRPDGK MAV_2510|M.avium_104 ARMNPEVLMIESDHDLRNSADFLVIDKIAKTVFRVPGIGRVQAITRPQGT MAB_4382c|M.abscessus_ATCC_199 AKMNPDLLLVESDHDLRNPADFLVIDKIAKALARVRGIAQVQTITRPDGK MLBr_02378|M.leprae_Br4923 ARMKPEILMIESDHDMRNPADFLILDKLARGIFRVPGISRVQAITRPDGT *:::*::*::*****:**.:***:::::*: : * *:.:** ****:*. MSMEG_0225|M.smegmatis_MC2_155 PIEHTSIPFTISMQGTTQTMNQKYMQDRMADMLVQADQMQVTVDTMTKMI TH_3260|M.thermoresistible__bu PIEHSSIPFMISQQGTLQILNQQYMQDRMADMLVQADEMQLMIDTMDKMI Mflv_3435|M.gilvum_PYR-GCK PIKHTSIPFQMSMQGTTQRLNEKYMQDRMADMLVQADEMANTIKTMEKMS Mvan_3189|M.vanbaalenii_PYR-1 PIKHTSIPFQMSMQGTTQRLNEKYMQDRMADMLVQADEMANTIATMEKMS Mb0695c|M.bovis_AF2122/97 PIEHTSIPFLISMQGTSQKLTEKYNQDLTARMLEQVNDIQSNIDQMERMH Rv0676c|M.tuberculosis_H37Rv PIEHTSIPFLISMQGTSQKLTEKYNQDLTARMLEQVNDIQSNIDQMERMH MMAR_1005|M.marinum_M PIEHTSIPFLISMQGTSQKLTEKYNQDLTTSMLQQVNDIQTNIDQMERMH MUL_0757|M.ulcerans_Agy99 PIEHTSIPFLISMQGTSQKLTEKYNQDLTTSMLQQVNDIQTNIDQMERMH MAV_2510|M.avium_104 PIEHTSIPFQISMQGVTQQMNQKYQQDQMADMLHQADMMQTTIDSMEKMQ MAB_4382c|M.abscessus_ATCC_199 PIKHTSIPFNMSTANTAQTLTNDYSQANFANLLKQADAMQVTIDSMEKMQ MLBr_02378|M.leprae_Br4923 AMDHTSIPFQISMQNAGQVQTMKYQKDRMNDLLRQAENMAETIASMRRMH .:.*:**** :* .. * . .* : :* *.: : : * :* MSMEG_0225|M.smegmatis_MC2_155 ALMEQMRDTMNSMVGKMHGMVDDIKELRDNISDFDDFFRPIRNYLYWEPH TH_3260|M.thermoresistible__bu ALMEEMVETTDNMVRDMDEMAAHVAEMRDSISEFDDFFRPIRNYFYWEPH Mflv_3435|M.gilvum_PYR-GCK GLTAQMADITHSMVTKMEGMVVDIEDLRDSIANFDDFFRPIRNYFYWEPH Mvan_3189|M.vanbaalenii_PYR-1 NLTAQMADITHSMVSKMENMLTDIEDLRDSIANFDDFFRPIRNYFYWEPH Mb0695c|M.bovis_AF2122/97 SLTQQMADVTHEMVIQMTGMVVDVEELRNHIADFDDFFRPIRSYFYWEKH Rv0676c|M.tuberculosis_H37Rv SLTQQMADVTHEMVIQMTGMVVDVEELRNHIADFDDFFRPIRSYFYWEKH MMAR_1005|M.marinum_M DLTQQMADVTHQMVIQMKGMVVDVEELRNHIADFDDFFRPIRSYFYWEKH MUL_0757|M.ulcerans_Agy99 DLTQQMADVTHQMVIQMKGMVVDVEELRNHIADFDDFFRPIRSYFYWEKH MAV_2510|M.avium_104 SITVQMSNDMHVMVQKMHDMTIDINDLRNKMADFEDFFRPMRSYFYWEKH MAB_4382c|M.abscessus_ATCC_199 AITQQMAEVTASMSANMKNTAQDINQLRDNMSNFDDQFRPIRNYFYWEKH MLBr_02378|M.leprae_Br4923 QLMALLTENTHHILNDTVEMQKTTSKLRDEIANFDDFWRPIRSYFYWERH : : : : . .:*: :::*:* :**:*.*:*** * MSMEG_0225|M.smegmatis_MC2_155 CYNIPMCYSLRSIFDTMDGIDTMTADFEQIVPDMDRMNALIPVMIANMEP TH_3260|M.thermoresistible__bu CYNIPVCWAMRSVFDTLDGINTMTDDIQNMLPHMHRLNDLMPQMLTLLPT Mflv_3435|M.gilvum_PYR-GCK CYNIPVCWALRSVFDTLDGINIMTDDFKAIIPDMKRLDTLMPQMVALMPE Mvan_3189|M.vanbaalenii_PYR-1 CYNIPVCWALRSVFDTLDGINVMTDDFREILPDMKRLDSLMPQMVALMPE Mb0695c|M.bovis_AF2122/97 CYDIPVCWSLRSVFDTLDGIDVMTEDINNLLPLMQRLDTLMPQLTAMMPE Rv0676c|M.tuberculosis_H37Rv CYDIPVCWSLRSVFDTLDGIDVMTEDINNLLPLMQRLDTLMPQLTAMMPE MMAR_1005|M.marinum_M CFDIPVCWSLRSVFDTLDGVDLMTEDINNLLPLMERLDTLMPQMTAMMPE MUL_0757|M.ulcerans_Agy99 CFDIPVCWSLRSVFDTLDGVDLMTEDINNLLPLMERLDTLMPQMTAMMPE MAV_2510|M.avium_104 CYDIPVCWSLRSVFDALDGIDTMTDDIQSLLPIMDHLDTLMPQMVALMPS MAB_4382c|M.abscessus_ATCC_199 CFDIPMCWALRSVFDALDGISLMSDDFDTLVPDIQRMAGLMPQMVVLMPP MLBr_02378|M.leprae_Br4923 CFNIPICWSFRSIFDALDGVDQIDERLNSIVGDIKNMDLLMPQMLEQFPP *::**:*:::**:**::**:. : : :: :..: *:* : : MSMEG_0225|M.smegmatis_MC2_155 MITTMKTMKTMMLTMQATNAGLQDQMAAMQENSTAMGEAFDKAKNDDSFY TH_3260|M.thermoresistible__bu TVATMKTMRSMLLTMQATNAGLQDQMAEMQENANAMGEAFDQARNDDSFY Mflv_3435|M.gilvum_PYR-GCK MIETMKTMRTMMLTMYQSQKGQQDQMAAMSEDADAMGEAFDDSMNDDSFY Mvan_3189|M.vanbaalenii_PYR-1 MIETMKTMRTMMLTMYQSQKGQQDQMAAMSEDADAMGEAFDDSMNDDSFY Mb0695c|M.bovis_AF2122/97 MIQTMKSMKAQMLSMHSTQEGLQDQMAAMQEDSAAMGEAFDASRNDDSFY Rv0676c|M.tuberculosis_H37Rv MIQTMKSMKAQMLSMHSTQEGLQDQMAAMQEDSAAMGEAFDASRNDDSFY MMAR_1005|M.marinum_M MIQTMKSMKAQMLSMHSTQQGLQDQMAAMQEDSSAMGEAFDSSRNDDSFY MUL_0757|M.ulcerans_Agy99 MIQTMKSMKAQMLSMHSTQQGLQDQMAAMQEDSSAMGEAFDSSRNDDSFY MAV_2510|M.avium_104 MIENMKAMKTTMLTMYSTQKGLQDQQNEAQKNSNAMGKAFDASKNDDSFY MAB_4382c|M.abscessus_ATCC_199 MIASMKEQKQIMLSQYQVQKAQQDQTMAMQANASAMGQAFDDAKNDDSFY MLBr_02378|M.leprae_Br4923 MIESMESMRTIMLTMHSTMSGIFDQMNELSDNANTMGKAFDTAKNDDSFY : .*: : :*: . ** . :: :**:*** : ****** MSMEG_0225|M.smegmatis_MC2_155 LPPETFDNPDFKRGMKMFLSPDGHAVRFIISHEGDPMSPEGIQKIDDIKL TH_3260|M.thermoresistible__bu LPPEAFDNPDFQRGLEQFLSPDGHAVRFIISHQGDPMTPEGLAKIEPIKK Mflv_3435|M.gilvum_PYR-GCK LPPEIFENADFQRGLEQFLSPDGHAVRFIISHEGDPLSPEGVAKIDKIKT Mvan_3189|M.vanbaalenii_PYR-1 LPPEIFENKDFQRGLEQFLSPDGHAVRFIISHEGDPLSPEGVAKIDKIKT Mb0695c|M.bovis_AF2122/97 LPPEVFDNPDFQRGLEQFLSPDGHAVRFIISHEGDPMSQAGIARIAKIKT Rv0676c|M.tuberculosis_H37Rv LPPEVFDNPDFQRGLEQFLSPDGHAVRFIISHEGDPMSQAGIARIAKIKT MMAR_1005|M.marinum_M LPPEVFNNPDFKRGLEQFLSPDGHAVRFIISHEGDPMSQAGINHIDKIKT MUL_0757|M.ulcerans_Agy99 LPPEVFNNPDFKRGLEQFLSPDGHAVRFIISHEGDPMSQAGINHIDKIKT MAV_2510|M.avium_104 LPPETFNNKEFKKGMKNFISPDGHAVRFIISHDGDPMTQEGISHIGAIKK MAB_4382c|M.abscessus_ATCC_199 LPPEAFETADFKSGIKLFVSPNGHAVRFTIFHQSDPLTEEGTSRVEPLKT MLBr_02378|M.leprae_Br4923 LPPEVFKNTDFKRAMKSFLSSDGHAARFIILHRGDPASVAGIASINAIRT **** *.. :*: .:: *:*.:***.** * * .** : * : :: MSMEG_0225|M.smegmatis_MC2_155 AAKEAIKGTPLEGSKIYLGGTAATFKDMQEGANYDLIIAGIAALCLIFII TH_3260|M.thermoresistible__bu AAVEAIKGTPLEGSRVYLGGTAAVFKDMSDGTKYDLIIAAIAAVCLIFII Mflv_3435|M.gilvum_PYR-GCK AAKEAVKGTPLEGSKIYLGGTAAVFKDMQDGNNYDLLIAGIAALGLIFII Mvan_3189|M.vanbaalenii_PYR-1 AAKEAIKGTPLEGSKIYLGGTAATFKDMQDGNNYDLLIAGISALGLIFII Mb0695c|M.bovis_AF2122/97 AAKEAIKGTPLEGSAIYLGGTAAMFKDLSDGNTYDLMIAGISALCLIFII Rv0676c|M.tuberculosis_H37Rv AAKEAIKGTPLEGSAIYLGGTAAMFKDLSDGNTYDLMIAGISALCLIFII MMAR_1005|M.marinum_M AAKEAIKGTPLEGSTIYLGGTAAMFKDLSDGNTFDLMIAGISALCLIFII MUL_0757|M.ulcerans_Agy99 AAKEAIKGTPLEGSTIYLGGTVAMFKDLSDGNTFDLMIAGISALCLIFII MAV_2510|M.avium_104 AAYEALKGTPLEGSKIYLAGTASIYKDLSDGNNYDLLIAGISSLCLIFII MAB_4382c|M.abscessus_ATCC_199 AAEDAIKGTPLEGSSIYVGGSAALYKDMQEGADYDLLIAAVAALILIFLI MLBr_02378|M.leprae_Br4923 AAEEALKGTPLEDTKIYLAGTAAVFKDIDEGANWDLVIAGISSLCLIFII ** :*:******.: :*:.*:.: :**:.:* :**:**.:::: ***:* MSMEG_0225|M.smegmatis_MC2_155 MLIITRAVVASAVIVGTVVISLGSAFGLSVLIWQHLVGLELHWMVLAMAV TH_3260|M.thermoresistible__bu MLILTRAVVAAAVIVGTVTLSLAASFGVSVLIWQYIVGLEMHWMVFPMAL Mflv_3435|M.gilvum_PYR-GCK MLILTRAVVAAAVIVGTVVLSLAASFGLSVLFWQHILGQPLHWMVLAMAV Mvan_3189|M.vanbaalenii_PYR-1 MLILTRAIVAAAVIVGTVVLSLAASFGLSVLFWQHILGTELHWMVLAMAV Mb0695c|M.bovis_AF2122/97 MLIITRSVVAAAVIVGTVVLSLGASFGLSVLIWQHILGIELHWLVLAMAV Rv0676c|M.tuberculosis_H37Rv MLITTRSVVAAAVIVGTVVLSLGASFGLSVLIWQHILGIELHWLVLAMAV MMAR_1005|M.marinum_M MLIITRSVVAAAVIVGTVVLSLGASFGLSVLIWQHILGIELHWLVLAMAV MUL_0757|M.ulcerans_Agy99 MLIITRSVVAAAVIVGTVVLSLGASFGLSVLIWQHVLGIELHWLVLAMAV MAV_2510|M.avium_104 MLIITRGVVASAVIVGTVLLSLGASFGLSVLIWQHLIGIELHWMVLAMSV MAB_4382c|M.abscessus_ATCC_199 MVLLTRAVVAAAVIVGTVVLSLGASFGLSVLLWQHIIGTPLHWMVLPMAV MLBr_02378|M.leprae_Br4923 MLIITRAFVAAAVIVGTVALSLGASFGLSVLLWQHILGIELHYLVLAMSV *:: **..**:******* :**.::**:***:**:::* :*::*:.*:: MSMEG_0225|M.smegmatis_MC2_155 IVLLAVGADYNLLLVSRIKEEIHAGLDTGMIRAMGGSGSVVTAAGLVFAF TH_3260|M.thermoresistible__bu IILLAVGADYNLLVVARLREEIPAGLNTGMIRAMGGSGSVVTAAGLVFGL Mflv_3435|M.gilvum_PYR-GCK IILLAVGADYNLLLVSRLKEEIHAGIGTGIIRAMGGSGSVVTAAGLVFAL Mvan_3189|M.vanbaalenii_PYR-1 IVLLAVGADYNLLLVSRLKEEIHAGIGTGIIRAMGGSGSVVTAAGLVFAL Mb0695c|M.bovis_AF2122/97 IILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGSGSVVTAAGLVFAF Rv0676c|M.tuberculosis_H37Rv IILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGSGSVVTAAGLVFAF MMAR_1005|M.marinum_M IILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGSGSVVTAAGLVFAF MUL_0757|M.ulcerans_Agy99 IILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGSGSVVTAAGLVFAF MAV_2510|M.avium_104 IILLAVGADYNLLLVARFKEEIHAGLNTGIIRSMGGTGSVVTSAGLVFAF MAB_4382c|M.abscessus_ATCC_199 IILLAVGADYNLLLVSRMKEELHAGLHTGTIRSMAGTGSVVTSAGLVFAF MLBr_02378|M.leprae_Br4923 IVLLAVGSDYNLLLVSRFKQEIQAGLKTGIIRSMGGTGKVVTNAGLVFAF *:*****:*****:*:*:::*: **: ** **:*.*:*.*** *****.: MSMEG_0225|M.smegmatis_MC2_155 TMMSMAVSELAIIGQVGTTIGLGLLFDTLVIRSFMTPSIAALLGKWFWWP TH_3260|M.thermoresistible__bu TMMVMVVSDLTVMGQVGTTIGLGLLFDTFVVRSFMMPSIATLLGRWFWWP Mflv_3435|M.gilvum_PYR-GCK TMMSMSVSELTVIGQVGTTIGLGLLFDTLVIRAFMTPSIAALLGPWFWWP Mvan_3189|M.vanbaalenii_PYR-1 TMMSMAVSELTVIGQVGTTIGLGLLFDTLVIRAFMTPSIAALLGPWFWWP Mb0695c|M.bovis_AF2122/97 TMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTPSIAALLGKWFWWP Rv0676c|M.tuberculosis_H37Rv TMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTPSIAALLGKWFWWP MMAR_1005|M.marinum_M TMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTPSIAALLGKWFWWP MUL_0757|M.ulcerans_Agy99 TMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTPSIAALLGKWFWWP MAV_2510|M.avium_104 TMMTMAVSELTVIGQVGTTIGLGLLFDTLIVRSLMTPSIAALLGKWFWWP MAB_4382c|M.abscessus_ATCC_199 TMMGMMVSSFTVIGQIGTTIGLGLLFDTLVVRSFMTPSIASLLGRWFWWP MLBr_02378|M.leprae_Br4923 TMASMVVSDLRVIGQVGTTIGLGLLFDTLIVRSFMMPSIAALLGRWFWWP ** : **.: ::.*:*****:******:::*::* ****:*** ***** MSMEG_0225|M.smegmatis_MC2_155 QMVRRRPKPSPWPKPIQREPADAVN--- TH_3260|M.thermoresistible__bu QFVRKRPVPQPWPSVPPRGPATTDRVSV Mflv_3435|M.gilvum_PYR-GCK QRVRTRPVPAPWPRSGGLQSDPSEGVRA Mvan_3189|M.vanbaalenii_PYR-1 QRVRTRPVPAPWPRPGGLQSDPSEGVKV Mb0695c|M.bovis_AF2122/97 QVVRQRPVPQPWPSPASARTFALV---- Rv0676c|M.tuberculosis_H37Rv QVVRQRPIPQPWPSPASARTFALV---- MMAR_1005|M.marinum_M QVVRQRPAPQPWPTPAPTP--ATTSV-- MUL_0757|M.ulcerans_Agy99 QVVRQRPAPQPWPTPAPTPPPATTSV-- MAV_2510|M.avium_104 QRVRQRPVPSPWPKPAAQEREVLADA-- MAB_4382c|M.abscessus_ATCC_199 MVVRPRPRPQPWPQPLHAGAAEAVRA-- MLBr_02378|M.leprae_Br4923 QQGRTRPLLTVAAPVGLPPDRSLVYSD- * ** .