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ITRVFRPSSREVRTEPALLARWIRRLAIPIMLGWLAIIVLINILVPSLQQVAADNSVSMNPAGAPSLQAI KEMGRVFGESRSDSVALILLEGRQPLGADAHEYYDDLVTRLRADTAHVQNVQDFWGDPLTEGSAQSPDGK AAYLQLYLSGNIGDTLANESVGAVWAAVDARPPPPGVKVYVTGPAALQADLIHSAERTVRTIKIATFTVI IVLMLFFFRSVPTVLVLLGVVGIQLSAATGVAAVIGYLGVVELSTFAVNLVVAMAIATGTDYAIFLIGRY QEARAAGVDRESAYYEMWHGTAHVVLASGLTIAGAALCMSLTRMPYLQSLGVPTAVAMLVALSVALTLGP AAVTVASRFGLLEPKRAIRIRFWRRIGTAVVRWPAPILLASLAAALVGLIALPFYQPSYNDRRYIPGDIE ANAGYAAAEQHFSAARMNPEVLLVEADHDLRNPADFLVIDKLAKAIFRVPGVARVQAITRPDGAPIQHTS IPFMMSMQGVGLQQNMKLMFDRIDDMKAQAESLGNTVAIMKRMQASMSRMAGVGDGLVVDMDDMQTAVRD ARDSLADFEDFFRPIRNYFHWEPHCFDIPVCWALRSVSDSVDGIDAMTDQMDRMIKGMTDLNALIPEMIA QFPPMIATMESMQQMMLTMHSTMSGMYRQMDELSHGAAEMGKAFDAARNDDSFYLPSEVFDNPDFRRAMD LFISPDGKSLRMIISHRGDPASAEGISRVDPIKLAAIEALKGTPLENAKVSLGGTASVYHDLSEGTRYDL VIAVIATVCLIFAIMLLITRSLVAAMVIVGTVLLSLGASVGLSVLLWQYIVGLPLQWMVMSMAVIILLAV GADYNLMMVARFKEEMPAGLKTGIIRAMGGAGSVVTAAGLVFAFTMTSMVVSDLRTIGQIGTFIGLGLLF DTLIVRSFMVPSIAALLGRWFWWPINVRTRPARARPVRPQA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3174 | mmpL4_5 | - | 100% (952) | transmembrane transport protein MmpL4_5 |
| M. marinum M | MMAR_0771 | mmpL5_2 | 0.0 | 60.42% (945) | transmembrane transport protein MmpL5_2 |
| M. marinum M | MMAR_0255 | mmpL5_4 | 0.0 | 58.88% (929) | transmembrane transport protein, MmpL5_4 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0458c | mmpL4 | 0.0 | 59.49% (948) | transmembrane transport protein MmpL4 |
| M. gilvum PYR-GCK | Mflv_2705 | - | 0.0 | 63.79% (939) | transport protein |
| M. tuberculosis H37Rv | Rv0450c | mmpL4 | 0.0 | 59.60% (948) | transmembrane transport protein MmpL4 |
| M. leprae Br4923 | MLBr_02378 | - | 0.0 | 59.08% (931) | hypothetical protein MLBr_02378 |
| M. abscessus ATCC 19977 | MAB_2301 | - | 0.0 | 63.57% (936) | putative membrane protein, mmpL |
| M. avium 104 | MAV_2510 | - | 0.0 | 59.53% (934) | MmpL4 protein |
| M. smegmatis MC2 155 | MSMEG_4383 | - | 0.0 | 59.21% (939) | MmpL5 protein |
| M. thermoresistible (build 8) | TH_3260 | - | 0.0 | 59.10% (929) | PUTATIVE MmpL4 protein |
| M. ulcerans Agy99 | MUL_0757 | mmpL5 | 0.0 | 59.46% (925) | transmembrane transport protein, MmpL5 |
| M. vanbaalenii PYR-1 | Mvan_3833 | - | 0.0 | 63.47% (939) | transport protein |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_2510|M.avium_104 MSTTFDDTRTDAIPVVKEPVRE------KIPRFIRAFAVPIIIGWIALIA
MUL_0757|M.ulcerans_Agy99 MTATTTDTPTDVVPPAEHPPRP------FIPRMIRTFAVPLILGWVLLIA
TH_3260|M.thermoresistible__bu MTANPGHVRTDEAPTDRLDIKVSTHGPSFISTWIRRLSLPIIVGWIALIA
MSMEG_4383|M.smegmatis_MC2_155 MAVSTDR------PAARESEHTG------IARWIRRLAIPIILGWIALLG
Mb0458c|M.bovis_AF2122/97 MSTKFAN-------DSNTNARPEK---PFIARMIHAFAVPIILGWLAVCV
Rv0450c|M.tuberculosis_H37Rv MSTKFAN-------DSNTNARPEK---PFIARMIHAFAVPIILGWLAVCV
MLBr_02378|M.leprae_Br4923 MTVKCAN-------DLDTHTKP-----PFVARMIHRFAVPIILVWLAIAV
Mflv_2705|M.gilvum_PYR-GCK ----MSS------SRDRAALREPR----SVARWIRRLAVPIILGWLLLAV
Mvan_3833|M.vanbaalenii_PYR-1 ----MRA------HADR-DLRDPT----PVARWIRRLAIPIILGWVLLVA
MMAR_3174|M.marinum_M MITRVFR------PSSREVRTEPA----LLARWIRRLAIPIMLGWLAIIV
MAB_2301|M.abscessus_ATCC_1997 ----MSG------SHAGRSAAEPT----FLAKWIRRLSIPIVIGWLAIVF
:. *: :::*::: *: :
MAV_2510|M.avium_104 VLNVVVPQLDEVGKMRSVEMTPDDAQSVVATKRMGAVFNEYKSNSSVMIV
MUL_0757|M.ulcerans_Agy99 VLNSVVPQLEVVGQMQAVSMSPDAAPSMISMKHIGKVFREGDSDSAAMIV
TH_3260|M.thermoresistible__bu LLNITVPQLEVVGEMRAVSMSPDEAPSMVAMKRVGELFDEGSSDSQVMIV
MSMEG_4383|M.smegmatis_MC2_155 VLGATVPSLEEVGQMRSVSMSPDYAPSVIAMKRVGEVFEEFKSDSSAMIV
Mb0458c|M.bovis_AF2122/97 VVTVFVPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKEGDSDSFAMVI
Rv0450c|M.tuberculosis_H37Rv VVTVFVPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKEGDSDSFAMVI
MLBr_02378|M.leprae_Br4923 TVSVFIPSLEDVGQERSVSLSPKDAPSYIAMQKMGQVFNEGNSDSVIMIV
Mflv_2705|M.gilvum_PYR-GCK ALNALVPQLEVVAAKNAVSMSPSNAPSMQAMADMGRLFEESDSDSIALIV
Mvan_3833|M.vanbaalenii_PYR-1 ALNLLVPQLEVVAAQNAVSMSPSDAPAMQAMSDMGRLFGESDSDSIAMVV
MMAR_3174|M.marinum_M LINILVPSLQQVAADNSVSMNPAGAPSLQAIKEMGRVFGESRSDSVALIL
MAB_2301|M.abscessus_ATCC_1997 ALNTFVPQLEQVGKEHTVSLSPQSAPSMQAMKHMGKMFKESDSDSVVMIV
: :*.*: *. .:*.:.* * : : :* :* * *:* :::
MAV_2510|M.avium_104 LEGQ--QPLGADAHAYYDEIVRRLNADTKHVEHVQDMWSDPLTGAGAQSN
MUL_0757|M.ulcerans_Agy99 LEGQ--EPLGAAAHKFYDKMITKLRADTKHVQSVQDFWGDPLTATGAQSG
TH_3260|M.thermoresistible__bu LEGE--EPLGADARAFYDELVKRLEADDAHVENVQDLWSDPLTATGVQSP
MSMEG_4383|M.smegmatis_MC2_155 LEGD--EPLGDDAHIFYNDMVDRLEADTEHVEHVQDFWGDPLTEAGAQSN
Mb0458c|M.bovis_AF2122/97 IEGN--QPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDPLTAAGVQSN
Rv0450c|M.tuberculosis_H37Rv IEGN--QPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDPLTAAGVQSN
MLBr_02378|M.leprae_Br4923 LEGD--KPLGDDAHRFYDGLIRKLRADK-HVQSVQDFWGDPLTAPGAQSN
Mflv_2705|M.gilvum_PYR-GCK LESETDQPLGDDAHEYYDGLIAALLADTENVRNIQDTWGDPLTEAAAQSS
Mvan_3833|M.vanbaalenii_PYR-1 LEGE--QPLGDDAHAYYDQLIEKLEAAPDHVRNIQDMWGDPLTEAAAQST
MMAR_3174|M.marinum_M LEGR--QPLGADAHEYYDDLVTRLRADTAHVQNVQDFWGDPLTEGSAQSP
MAB_2301|M.abscessus_ATCC_1997 LEGQ--ERLGPGSHKFYDEMVARLRADTKHVQHVQDFWGDPLTEAGAQST
:*. : ** :: :*: :: * * :*. :** *.**** ..**
MAV_2510|M.avium_104 DGKASYVQVYLAGNQGEALANESVESVQNIVKSV---------QAPNGVK
MUL_0757|M.ulcerans_Agy99 DGKAAYVQVKLAGNQGESLANESVEAVKTIVDSL---------QAPPGVK
TH_3260|M.thermoresistible__bu DGKSAYVQVKLAGNQGEALANESVETVREMIATVSEE------MAPEGVQ
MSMEG_4383|M.smegmatis_MC2_155 DGRAAYVQVFLAGNMGEALANESVQAVQELVEGL---------QPPPGVK
Mb0458c|M.bovis_AF2122/97 DGKAAYVQLSLAGNQGTPLANESVEAVRSIVEST---------PAPPGIK
Rv0450c|M.tuberculosis_H37Rv DGKAAYVQLSLAGNQGTPLANESVEAVRSIVEST---------PAPPGIK
MLBr_02378|M.leprae_Br4923 DGKAAYVQLSLAGNQGELLAQESIDAVRKIVVQT---------PAPPGIT
Mflv_2705|M.gilvum_PYR-GCK DGRAAYATLNLAGNMGETESNEAVAAVRDIVANSPP---------PPGVT
Mvan_3833|M.vanbaalenii_PYR-1 DGHAAYVALNLAGNMGETKSNESVAAVRDIVADSPP---------PPGVQ
MMAR_3174|M.marinum_M DGKAAYLQLYLSGNIGDTLANESVGAVWAAVDARPP---------PPGVK
MAB_2301|M.abscessus_ATCC_1997 DGKATYVQVNLAGNMGETLSNESTEAARNIVKQLEADWTKDGNKLPDGLT
**:::* : *:** * ::*: :. : * *:
MAV_2510|M.avium_104 AYVTGPAALSADQHTAGDRSLQLITAATFTVIIGMLLLVYRSVITVLLTL
MUL_0757|M.ulcerans_Agy99 VYVTGSAALVADQQLAGDRSLQLIEMVTFTVIIVMLLLVYRSIITAAIML
TH_3260|M.thermoresistible__bu AFVTGGAAMSADQQEAGDSSLRVIEALTFLVITTMLLFVYRSVITVLIAL
MSMEG_4383|M.smegmatis_MC2_155 VYVTGGSALANDQQISGDRSVRIIEAVTFLVIITMLLLVYRSIVTVLITL
Mb0458c|M.bovis_AF2122/97 AYVTGPSALAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSIITVVLLL
Rv0450c|M.tuberculosis_H37Rv AYVTGPSALAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSIITVVLLL
MLBr_02378|M.leprae_Br4923 AWVTGASALIADMHHSGDKSMIRITATSVIVILVTLLLVYRSFITVILLL
Mflv_2705|M.gilvum_PYR-GCK VHVTGPAALIADVNIAGERSMALVLLVTFVVIIVLLLFFYRSISTVLLLL
Mvan_3833|M.vanbaalenii_PYR-1 VHVTGPAALTADVNIAGESSMALILLVTFVVIIVLLLFFYRSITTVVLLL
MMAR_3174|M.marinum_M VYVTGPAALQADLIHSAERTVRTIKIATFTVIIVLMLFFFRSVPTVLVLL
MAB_2301|M.abscessus_ATCC_1997 VYVTGPGALQTDMNHAGDGSLQLITGLTFLVIVVMLLFFYRSIFTVIMVF
. *** .*: * :.: :: : :. ** :*:.:**. *. : :
MAV_2510|M.avium_104 VMVVLELSAARGMVAFLGYYKIIGLSTFATNLLVTLAIAAATDYAIFLIG
MUL_0757|M.ulcerans_Agy99 TMVVLGLLATRGGVAFLGYHRIIGLSTFATNLLVVLAIAAATDYAIFLIG
TH_3260|M.thermoresistible__bu FMVLIGLLTTRGVVAFLGYHNIIGLSTFATSLLVTLAIAIAVDYAIFLIG
MSMEG_4383|M.smegmatis_MC2_155 FLVVICLQSARGVVAFLGYHELIGLSTFATQLLVTLAIAASTDYAIFLIG
Mb0458c|M.bovis_AF2122/97 ITVGVELTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFIIG
Rv0450c|M.tuberculosis_H37Rv ITVGVELTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFIIG
MLBr_02378|M.leprae_Br4923 FTVGIESAVARGVVALLGHTGLIGLSTFAVNLLTSLAIAAGTDYGIFITG
Mflv_2705|M.gilvum_PYR-GCK VVVGIQLLVARGVVAALAHVGVIGLSTYATNLLISLAVAAGTDYAIFLVG
Mvan_3833|M.vanbaalenii_PYR-1 IMVGVQMSVARGVVAALGHFQVIGLSTFAVNLLISLAVAAGTDYAIFLVG
MMAR_3174|M.marinum_M GVVGIQLSAATGVAAVIGYLGVVELSTFAVNLVVAMAIATGTDYAIFLIG
MAB_2301|M.abscessus_ATCC_1997 MLVGIQLSAARGVIAFLGNTEIIGLSTFAVNLLVMLSIAAGTDYAIFLIG
* : : * * :. : *:*:*..*: :::* ..**.**: *
MAV_2510|M.avium_104 RYQEARAVGESREDAYYTMYKGTAHVVAGSGMTIAGATFCLHFTNLPYFQ
MUL_0757|M.ulcerans_Agy99 RYQEARGLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFTRLPYFQ
TH_3260|M.thermoresistible__bu RYQEARSVGADRATAYHTMFGGTAHVILASGLTIAGATFCLSFTRLPYFQ
MSMEG_4383|M.smegmatis_MC2_155 RYQEARTLGESKEQAYYTMFRGTAHVVLGSGMTIAGATLCLHFTRLPYFQ
Mb0458c|M.bovis_AF2122/97 RYQEARQAGEDKEAAYYTMYRGTAHVILGSGLTITGATFCLSFARMPYFQ
Rv0450c|M.tuberculosis_H37Rv RYQEARQAGEDKEAAYYTMYRGTAHVILGSGLTIAGATFCLSFARMPYFQ
MLBr_02378|M.leprae_Br4923 RYQEARQANENKEAAFYTMYRGTFHVILGSGLTISGATFCLSFARMPYFQ
Mflv_2705|M.gilvum_PYR-GCK RYQEARASGADHEEAYYEMFHGTAHVVLGSGLTIAGAMLCLSFTRMPYFQ
Mvan_3833|M.vanbaalenii_PYR-1 RYQEARASGADPEAAYYEMFGGTAHVVLGSGLTIAGAMYCLSFARMPYFQ
MMAR_3174|M.marinum_M RYQEARAAGVDRESAYYEMWHGTAHVVLASGLTIAGAALCMSLTRMPYLQ
MAB_2301|M.abscessus_ATCC_1997 RYQEARAMGADKEAAYYEMFHGTAHVILGSGMTIAGAMYCLSFTRMPYFQ
****** . . *:: *: ** **: .**:**:** *: ::.:**:*
MAV_2510|M.avium_104 TLGIPLAIGMVVVVAAALTLGPAVISVASRFRQTLEPRRTQRIRGWRKVG
MUL_0757|M.ulcerans_Agy99 TLGVPLAIGMVIVVATALTLGPALIAVMSRFGKLLEPKRMARVRGWRKIG
TH_3260|M.thermoresistible__bu SLGPPLAIGMIVLIVTSLTMGPAIITVATRFG-LLEPKRAARVRFWRKVG
MSMEG_4383|M.smegmatis_MC2_155 TLGIPMAVGMTIAVVAALTLGPAVITVMTRFGKILEPKRAMRIRGWRRLG
Mb0458c|M.bovis_AF2122/97 TLGIPCAVGMLVAVAVALTLGPAVLHVGSRFG-LFDPKRLLKVRGWRRVG
Rv0450c|M.tuberculosis_H37Rv TLGIPCAVGMLVAVAVALTLGPAVLHVGSRFG-LFDPKRLLKVRGWRRVG
MLBr_02378|M.leprae_Br4923 TLGVPCAVGMLIAVAVALTLGPAVLTVGSRFG-LFEPKRLIKVRGWRRIG
Mflv_2705|M.gilvum_PYR-GCK SMGIPCAVGIAAGVAVALTLGPAIVTVGSRFN-LLEPKRAMRIRAWRRIG
Mvan_3833|M.vanbaalenii_PYR-1 SMGVPCAVGILAGVAVALTLGPAIVTVGSRFG-LLEPKRAMRIRAWRRVG
MMAR_3174|M.marinum_M SLGVPTAVAMLVALSVALTLGPAAVTVASRFG-LLEPKRAIRIRFWRRIG
MAB_2301|M.abscessus_ATCC_1997 TLGVPCSVGLLVGVLVSLTLGPALITIGSRFG-LFEPKRAMRIRSWRKIG
::* * ::.: : .:**:*** : : :** ::*:* ::* **::*
MAV_2510|M.avium_104 TVVVRWPGPILVLTIGVALVGLLTLPGYRTNYNDRNYLPTDLPANEGYAA
MUL_0757|M.ulcerans_Agy99 AAIVRWPGPILIGAVALALVGLLTLPGYKTNYNDRNYLPADLPANEGYSA
TH_3260|M.thermoresistible__bu ASVVRWPGPIMVTTVAVTLVGLLALPGYRTNYNDRNYLPASFPSNAGYEA
MSMEG_4383|M.smegmatis_MC2_155 AFVVRWPGAVLMATVLLSLVGLLALPGYRTNYNDRNYLPDDLPAQEGFAA
Mb0458c|M.bovis_AF2122/97 TVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPANQGYAA
Rv0450c|M.tuberculosis_H37Rv TVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPANQGYAA
MLBr_02378|M.leprae_Br4923 TVVVRWPLPILITTCAIAMVGLLALPGYRTNYKDRAYLPASIPANQGFAA
Mflv_2705|M.gilvum_PYR-GCK TMVVRWPGPILVASLALALVGLAALPGYQTSYDDTRYVPESIPANAGLQA
Mvan_3833|M.vanbaalenii_PYR-1 ATVVRWPGPILVASLALALIGLAALPGYKTSYDDTRYIPESIPANAGLQA
MMAR_3174|M.marinum_M TAVVRWPAPILLASLAAALVGLIALPFYQPSYNDRRYIPGDIEANAGYAA
MAB_2301|M.abscessus_ATCC_1997 TTIVRWPGPVLAAAMAIAIIGLAALPGYRTSYDDKKYIPKDIPANAGFQA
: :**** .:: : :::** :** *:..*.* *:* : :: * *
MAV_2510|M.avium_104 ADRHFSQARMNPEVLMIESDHDLRNSADFLVIDKIAKTVFRVPGIGRVQA
MUL_0757|M.ulcerans_Agy99 AERHFSQARMNPEVLMVESDHDMRNSSDFLVINKIAKAIFGVEGISRVQA
TH_3260|M.thermoresistible__bu AERHFDPARLNPELLLIESDHDLRNPADFLVIEKIAKAVFQVEGISRVQG
MSMEG_4383|M.smegmatis_MC2_155 AERHFSPAKMNPELLLIETDHDIRNSADFLVIDKIAKAVFRVPGIGSVQA
Mb0458c|M.bovis_AF2122/97 ADRHFSQARMKPEILMIESDHDMRNPADFLVLDKLAKGIFRVPGISRVQA
Rv0450c|M.tuberculosis_H37Rv ADRHFSQARMKPEILMIESDHDMRNPADFLVLDKLAKGIFRVPGISRVQA
MLBr_02378|M.leprae_Br4923 ADRHFPQARMKPEILMIESDHDMRNPADFLILDKLARGIFRVPGISRVQA
Mflv_2705|M.gilvum_PYR-GCK ATQHFTLSRMSPEILIVEADRDLRNPADFLVLDRLAKRVFAVEGVARVQA
Mvan_3833|M.vanbaalenii_PYR-1 ATKYFSLSRMSPEVLIVEADRDLRNSSDFLILDRLAKRVFNVEGVARVQA
MMAR_3174|M.marinum_M AEQHFSAARMNPEVLLVEADHDLRNPADFLVIDKLAKAIFRVPGVARVQA
MAB_2301|M.abscessus_ATCC_1997 ADRHFSQARMNPEMLLIESDHDMRNSADFLVIDKIAKAVFRVPGIARVQA
* ::* :::.**:*::*:*:*:**.:***:::::*: :* * *:. **.
MAV_2510|M.avium_104 ITRPQGTPIEHTSIPFQISMQGVTQQMNQKYQQDQMADMLHQADMMQTTI
MUL_0757|M.ulcerans_Agy99 ITRPDGKPIEHTSIPFLISMQGTSQKLTEKYNQDLTTSMLQQVNDIQTNI
TH_3260|M.thermoresistible__bu ITRPEGTPIEHSSIPFMISQQGTLQILNQQYMQDRMADMLVQADEMQLMI
MSMEG_4383|M.smegmatis_MC2_155 ITRPQGEPLEFSTIPAQMSMGGTLQTMNRKYMLDRADDMLLQADEMQRTI
Mb0458c|M.bovis_AF2122/97 ITRPEGTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQADEMATTI
Rv0450c|M.tuberculosis_H37Rv ITRPEGTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQADEMATTI
MLBr_02378|M.leprae_Br4923 ITRPDGTAMDHTSIPFQISMQNAGQVQTMKYQKDRMNDLLRQAENMAETI
Mflv_2705|M.gilvum_PYR-GCK PSRPDGSPIAKTSIPFLISMQGVGQQQNMKLMQDRMDDMRTQADNLGKTL
Mvan_3833|M.vanbaalenii_PYR-1 PSRPDGAPIAHTSIPFLISMQGVGQQQNMKLMKDRIADMRVQADDIGETI
MMAR_3174|M.marinum_M ITRPDGAPIQHTSIPFMMSMQGVGLQQNMKLMFDRIDDMKAQAESLGNTV
MAB_2301|M.abscessus_ATCC_1997 ITRPQGTPIEHSSIPFLISMQSVGQRQNMKLMKDRMADMKVQADKMGENV
:**:* .: ::** :* .. . : * .: *.: : :
MAV_2510|M.avium_104 DSMEKMQSITVQMSNDMHVMVQKMHDMTIDINDLRNKMADFEDFFRPMRS
MUL_0757|M.ulcerans_Agy99 DQMERMHDLTQQMADVTHQMVIQMKGMVVDVEELRNHIADFDDFFRPIRS
TH_3260|M.thermoresistible__bu DTMDKMIALMEEMVETTDNMVRDMDEMAAHVAEMRDSISEFDDFFRPIRN
MSMEG_4383|M.smegmatis_MC2_155 ELMGRTIELMEEMAATTHSMVGKTHLMVEDVKELRDNISNFDDFLRPLRN
Mb0458c|M.bovis_AF2122/97 AVLTRMHSLMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDFWRPIRS
Rv0450c|M.tuberculosis_H37Rv AVLTRMHSLMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDFWRPIRS
MLBr_02378|M.leprae_Br4923 ASMRRMHQLMALLTENTHHILNDTVEMQKTTSKLRDEIANFDDFWRPIRS
Mflv_2705|M.gilvum_PYR-GCK GTMRTMYGLMTRLSEVTTVMIDDFTEMQQTVHQIRDMVANFDDQFRPVRN
Mvan_3833|M.vanbaalenii_PYR-1 ATMKTMYGLMTKFSNITTVMIDDMTEMRDTVHQIRDMVATFDDQFRPIRN
MMAR_3174|M.marinum_M AIMKRMQASMSRMAGVGDGLVVDMDDMQTAVRDARDSLADFEDFFRPIRN
MAB_2301|M.abscessus_ATCC_1997 VIMKRTLANMTTMAGITHSLVGDMHTLQGTIHEMRDSISNFDDWFRPIRN
: : :: . : . *: :: *:* **:*.
MAV_2510|M.avium_104 YFYWEKHCYDIPVCWSLRSVFDALDGIDTMTDDIQSLLPIMDHLDTLMPQ
MUL_0757|M.ulcerans_Agy99 YFYWEKHCFDIPVCWSLRSVFDTLDGVDLMTEDINNLLPLMERLDTLMPQ
TH_3260|M.thermoresistible__bu YFYWEPHCYNIPVCWAMRSVFDTLDGINTMTDDIQNMLPHMHRLNDLMPQ
MSMEG_4383|M.smegmatis_MC2_155 YLYWEPHCYDIPMCHSMRSIFDALDGMDTMTEAMEELLPDMDRLDALMPR
Mb0458c|M.bovis_AF2122/97 YFYWEKHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREMDRLMPQ
Rv0450c|M.tuberculosis_H37Rv YFYWEKHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREMDRLMPQ
MLBr_02378|M.leprae_Br4923 YFYWERHCFNIPICWSFRSIFDALDGVDQIDERLNSIVGDIKNMDLLMPQ
Mflv_2705|M.gilvum_PYR-GCK YFYWEPHCYNIPLCWSFRSLFDSMDGISTMTESFDKALVNMETMRSLLPQ
Mvan_3833|M.vanbaalenii_PYR-1 YFYWEPHCYNIPLCWSFRSLFDSMDGISVMTDTFDKAVANMDEMKALLPQ
MMAR_3174|M.marinum_M YFHWEPHCFDIPVCWALRSVSDSVDGIDAMTDQMDRMIKGMTDLNALIPE
MAB_2301|M.abscessus_ATCC_1997 YLYWEKHCFDIPMCWAMRSIFDTLDKIDEMTETMDGMVVNMERMDTLMPK
*::** **:.**:* ::**: *::* :. : : : : : : *:*.
MAV_2510|M.avium_104 MVALMPSMIENMKAMKTTMLTMYSTQKGLQDQQNEAQKNSNAMGKAFDAS
MUL_0757|M.ulcerans_Agy99 MTAMMPEMIQTMKSMKAQMLSMHSTQQGLQDQMAAMQEDSSAMGEAFDSS
TH_3260|M.thermoresistible__bu MLTLLPTTVATMKTMRSMLLTMQATNAGLQDQMAEMQENANAMGEAFDQA
MSMEG_4383|M.smegmatis_MC2_155 MVALMPPQIETMRKMRTMMLTMHQTQKGLQEQMGAMQEGQTAMGEAFNTA
Mb0458c|M.bovis_AF2122/97 MVAQIPPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMGKAFDAA
Rv0450c|M.tuberculosis_H37Rv MVAQIPPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMGKAFDAA
MLBr_02378|M.leprae_Br4923 MLEQFPPMIESMESMRTIMLTMHSTMSGIFDQMNELSDNANTMGKAFDTA
Mflv_2705|M.gilvum_PYR-GCK MLATFPPMIETMESMRQMMLTTYATMGGFYDQMDELTQDSTEMGKAFDEA
Mvan_3833|M.vanbaalenii_PYR-1 MLATFPPMIETMESMRQMMLTTYATMGGFYDQMDELTRDSTEMGKAFDAA
MMAR_3174|M.marinum_M MIAQFPPMIATMESMQQMMLTMHSTMSGMYRQMDELSHGAAEMGKAFDAA
MAB_2301|M.abscessus_ATCC_1997 MVSDMSAMIPIMEDMQRMMLTQHSTMSGFYNQMDEMSQNSTAMGKAFDAA
* :. : *. *: :*: * *: * . **:**: :
MAV_2510|M.avium_104 KNDDSFYLPPETFNNKEFKKGMKNFISPDGHAVRFIISHDGDPMTQEGIS
MUL_0757|M.ulcerans_Agy99 RNDDSFYLPPEVFNNPDFKRGLEQFLSPDGHAVRFIISHEGDPMSQAGIN
TH_3260|M.thermoresistible__bu RNDDSFYLPPEAFDNPDFQRGLEQFLSPDGHAVRFIISHQGDPMTPEGLA
MSMEG_4383|M.smegmatis_MC2_155 KNDDTFYLPPEIFNNADFKRGMDSFISPDGKAVRFIISHEGDPLTPEGIK
Mb0458c|M.bovis_AF2122/97 KNDDSFYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQSPEGIK
Rv0450c|M.tuberculosis_H37Rv KNDDSFYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQSPEGIK
MLBr_02378|M.leprae_Br4923 KNDDSFYLPPEVFKNTDFKRAMKSFLSSDGHAARFIILHRGDPASVAGIA
Mflv_2705|M.gilvum_PYR-GCK KNDDSFYLPPEVFENEDFKRAMESFFSPDGKTVRMLVSHRGDPTTPEALA
Mvan_3833|M.vanbaalenii_PYR-1 KNDDSFYLPPEVFENEDFKRAMESFFSPDGKTVRMLIAHRGNPTTDEALQ
MMAR_3174|M.marinum_M RNDDSFYLPSEVFDNPDFRRAMDLFISPDGKSLRMIISHRGDPASAEGIS
MAB_2301|M.abscessus_ATCC_1997 KNDDSFYLPPEIFDNADFKRGMKSFLSPDGKAVRMIISHRGDPATPEGLS
:***:****.* *.* :*::.:. *:*.**:: *::: * *:* : .:
MAV_2510|M.avium_104 HIGAIKKAAYEALKGTPLEGSKIYLAGTASIYKDLSDGNNYDLLIAGISS
MUL_0757|M.ulcerans_Agy99 HIDKIKTAAKEAIKGTPLEGSTIYLGGTVAMFKDLSDGNTFDLMIAGISA
TH_3260|M.thermoresistible__bu KIEPIKKAAVEAIKGTPLEGSRVYLGGTAAVFKDMSDGTKYDLIIAAIAA
MSMEG_4383|M.smegmatis_MC2_155 LIDQIKLAAKEAMKNTPWEGSKIYVGGTAAAFKDMQEGNNYDLIIAGISA
Mb0458c|M.bovis_AF2122/97 SIDAIRTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAISS
Rv0450c|M.tuberculosis_H37Rv SIDAIRTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAISS
MLBr_02378|M.leprae_Br4923 SINAIRTAAEEALKGTPLEDTKIYLAGTAAVFKDIDEGANWDLVIAGISS
Mflv_2705|M.gilvum_PYR-GCK RVEPIKIAAIEALKGTPLENAQIQLGGTAATFKDMSDGSRYDMMIAILSA
Mvan_3833|M.vanbaalenii_PYR-1 RVEPIKIAAIEALKGTPLENAQIQLGGTAATFKDMSDGSRYDLLIAVISA
MMAR_3174|M.marinum_M RVDPIKLAAIEALKGTPLENAKVSLGGTASVYHDLSEGTRYDLVIAVIAT
MAB_2301|M.abscessus_ATCC_1997 HVEPIKQAAIEAVKGTPLEDAKIELGGTAAVFKDMSDGAKYDLMIAGISA
: *: ** *::*.** *.: : :.**.: ::*:.:* :*::** :::
MAV_2510|M.avium_104 LCLIFIIMLIITRGVVASAVIVGTVLLSLGASFGLSVLIWQHLIGIELHW
MUL_0757|M.ulcerans_Agy99 LCLIFIIMLIITRSVVAAAVIVGTVVLSLGASFGLSVLIWQHVLGIELHW
TH_3260|M.thermoresistible__bu VCLIFIIMLILTRAVVAAAVIVGTVTLSLAASFGVSVLIWQYIVGLEMHW
MSMEG_4383|M.smegmatis_MC2_155 LCLIFIIMLLITRSVVAAAVIVGTVLVSLGASFGLSILVWQHILGIDLHF
Mb0458c|M.bovis_AF2122/97 LCLIFIIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHILAIHLHW
Rv0450c|M.tuberculosis_H37Rv LCLIFIIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHILAIHLHW
MLBr_02378|M.leprae_Br4923 LCLIFIIMLIITRAFVAAAVIVGTVALSLGASFGLSVLLWQHILGIELHY
Mflv_2705|M.gilvum_PYR-GCK LCLVLVIMLVLTRSLVAAVVIVGTVALSLGASFGVSVLIWQHLLGVELHW
Mvan_3833|M.vanbaalenii_PYR-1 LCLVLMIMLVLTRSLVAALVIVGTVTLSLGASFGISILIWQHIVGIELHW
MMAR_3174|M.marinum_M VCLIFAIMLLITRSLVAAMVIVGTVLLSLGASVGLSVLLWQYIVGLPLQW
MAB_2301|M.abscessus_ATCC_1997 LCLIFLIMLLITRSFVASLVIVGTVALSLGASFGLSVIIWQYILGIELHW
:**:: ***::**..:*: ****** :**.**.*:*:::**:::.: :::
MAV_2510|M.avium_104 MVLAMSVIILLAVGADYNLLLVARFKEEIHAGLNTGIIRSMGGTGSVVTS
MUL_0757|M.ulcerans_Agy99 LVLAMAVIILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGSGSVVTA
TH_3260|M.thermoresistible__bu MVFPMALIILLAVGADYNLLVVARLREEIPAGLNTGMIRAMGGSGSVVTA
MSMEG_4383|M.smegmatis_MC2_155 MVMAMAVIVLLAVGADYNLLLVARLKEELPAGINTGIIRAMGGSGSVVTA
Mb0458c|M.bovis_AF2122/97 LVLAMSVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVVTN
Rv0450c|M.tuberculosis_H37Rv LVLAMSVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVVTN
MLBr_02378|M.leprae_Br4923 LVLAMSVIVLLAVGSDYNLLLVSRFKQEIQAGLKTGIIRSMGGTGKVVTN
Mflv_2705|M.gilvum_PYR-GCK MVLVMSIIALIAVGSDYNLLLVSRFKEEIGAGIKTGIIRAIGGTGSVVSV
Mvan_3833|M.vanbaalenii_PYR-1 MVLALSIIALIAVGSDYNLLLVSRFKEEIPAGIKTGIIRAIGGTGSVVTV
MMAR_3174|M.marinum_M MVMSMAVIILLAVGADYNLMMVARFKEEMPAGLKTGIIRAMGGAGSVVTA
MAB_2301|M.abscessus_ATCC_1997 LVMQMAIIVLLAVGSDYNLLLVSRLKEELHGGLKTGIIRSMGGTGSVVTS
:*: :::* *:***:****::*:*:::*: .*::**:**::**:*.**:
MAV_2510|M.avium_104 AGLVFAFTMMTMAVSELTVIGQVGTTIGLGLLFDTLIVRSLMTPSIAALL
MUL_0757|M.ulcerans_Agy99 AGLVFAFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTPSIAALL
TH_3260|M.thermoresistible__bu AGLVFGLTMMVMVVSDLTVMGQVGTTIGLGLLFDTFVVRSFMMPSIATLL
MSMEG_4383|M.smegmatis_MC2_155 AGLVFAFTMMSMLVSEMTVVAQVGTTIGMGLLFDTLVIRSFMTPSIAALL
Mb0458c|M.bovis_AF2122/97 AGLVFAVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAALL
Rv0450c|M.tuberculosis_H37Rv AGLVFAVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAALL
MLBr_02378|M.leprae_Br4923 AGLVFAFTMASMVVSDLRVIGQVGTTIGLGLLFDTLIVRSFMMPSIAALL
Mflv_2705|M.gilvum_PYR-GCK AGVVFALTMASMVVSDLKVIAQVGTTIGLGLLFDTFIVRAFMMPSIATLL
Mvan_3833|M.vanbaalenii_PYR-1 AGVVFALTMASMVVSDLRVMAQVGTTIGLGLLFDTFIVRAFMMPAIATLL
MMAR_3174|M.marinum_M AGLVFAFTMTSMVVSDLRTIGQIGTFIGLGLLFDTLIVRSFMVPSIAALL
MAB_2301|M.abscessus_ATCC_1997 AGLVFAFTMAVMVVSDLRIIGQVGTTIALGLLFDTLIVRSFMTPAVATLL
**:**..** : **:: :.*:** *.:******:::*::* *::*:**
MAV_2510|M.avium_104 GKWFWWPQRVRQRPVPSPWPKPAAQEREVLADA-----------------
MUL_0757|M.ulcerans_Agy99 GKWFWWPQVVRQRPAPQPWPTPAPTPPPATTSV-----------------
TH_3260|M.thermoresistible__bu GRWFWWPQFVRKRPVPQPWPSVPPRGPATTDRVSV---------------
MSMEG_4383|M.smegmatis_MC2_155 GRWFWWPQVVRARPARGVVARALERDKAATH-------------------
Mb0458c|M.bovis_AF2122/97 GRWFWWPLRVRSRPARTPTVPSETQPAGRPLAMSSDRLG-----------
Rv0450c|M.tuberculosis_H37Rv GRWFWWPLRVRSRPARTPTVPSETQPAGRPLAMSSDRLG-----------
MLBr_02378|M.leprae_Br4923 GRWFWWPQQGRTRPLLTVAAPVGLPPD-RSLVYSD---------------
Mflv_2705|M.gilvum_PYR-GCK GRWFWWPLVVRSRPLRPR-------PQQQALGVGGQQG------------
Mvan_3833|M.vanbaalenii_PYR-1 GRWFWWPLVVRSRPLRLP-------PRT----------------------
MMAR_3174|M.marinum_M GRWFWWPINVRTRPARAR-------PVRPQA-------------------
MAB_2301|M.abscessus_ATCC_1997 GRWFWWPLNVRTRPLPPPRTTVAADPTPPPVPVGPGHGDDPITTEFPRPS
*:***** * **
MAV_2510|M.avium_104 -
MUL_0757|M.ulcerans_Agy99 -
TH_3260|M.thermoresistible__bu -
MSMEG_4383|M.smegmatis_MC2_155 -
Mb0458c|M.bovis_AF2122/97 -
Rv0450c|M.tuberculosis_H37Rv -
MLBr_02378|M.leprae_Br4923 -
Mflv_2705|M.gilvum_PYR-GCK -
Mvan_3833|M.vanbaalenii_PYR-1 -
MMAR_3174|M.marinum_M -
MAB_2301|M.abscessus_ATCC_1997 V