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MSDIAPVTGPVAVVTGAGRGAGLGIATALAAHGWRVYGTGRGIAEDPAWGTGIRVDHRDDDAVGRVFDRV GAEAGRLDLLVNNAAAISDNLVSAAPFWEKPRDLADVLTVGLRSSYIASWYAAPLLAAQDRALIAFTSSP GSVCYMHGPAYGAQKAGVDKMAADMAVDFRGTGVATVSVWMGILLTAKLRGAFDSDPDALAAFAAHAETP EFTGHVIDALFRDPGLADLSGHTVIGAELAARYGITDEGGRTPPSHRGMLGEPRTPSAVVVR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2659 | - | - | 100% (272) | short-chain dehydrogenase/reductase SDR |
| M. gilvum PYR-GCK | Mflv_1260 | - | 1e-74 | 53.02% (281) | short-chain dehydrogenase/reductase SDR |
| M. gilvum PYR-GCK | Mflv_1263 | - | 5e-15 | 30.00% (250) | short-chain dehydrogenase/reductase SDR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3579c | - | 2e-13 | 28.84% (267) | short chain dehydrogenase |
| M. tuberculosis H37Rv | Rv3549c | - | 2e-13 | 28.84% (267) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 6e-12 | 30.43% (184) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_0827 | - | 7e-12 | 28.04% (189) | putative short-chain dehydrogenase/reductase |
| M. marinum M | MMAR_3513 | - | 1e-113 | 76.60% (265) | oxidoreductase |
| M. avium 104 | MAV_3035 | - | 1e-117 | 80.15% (262) | short-chain dehydrogenase/reductase SDR |
| M. smegmatis MC2 155 | MSMEG_2923 | - | 1e-106 | 73.00% (263) | dehydrogenase/reductase SDR family protein member 1 |
| M. thermoresistible (build 8) | TH_1294 | - | 1e-105 | 71.48% (263) | dehydrogenase/reductase SDR family protein member 1 |
| M. ulcerans Agy99 | MUL_2755 | - | 3e-88 | 78.64% (206) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_3919 | - | 1e-126 | 80.88% (272) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2659|M.gilvum_PYR-GCK MSDIAP------------VTGPVAVVTGAGRGAGLGIATALAAHGWRVYG
Mvan_3919|M.vanbaalenii_PYR-1 MGDIA----------------PVAVVTGASRGAGQGIATALAGRGWRVYG
MSMEG_2923|M.smegmatis_MC2_155 --MDT----------------PVAVVTGASRGAGRGIAAALLAAGWKVYV
TH_1294|M.thermoresistible__bu VTSEA----------------PVAVVTGASRGAGRGIARALLSRGWRVYG
MMAR_3513|M.marinum_M MSDEA----------------LVAVVTGASRGAGRGIAAALAARGWRVYA
MUL_2755|M.ulcerans_Agy99 --------------------------------------------------
MAV_3035|M.avium_104 ----------------------MAVVTGASRGAGRGISAALADRGWRVYA
Mb3579c|M.bovis_AF2122/97 MTLAEAADAINFG-----LAGRVVLVTGGVRGVGAGISSVFAEQGATVIT
Rv3549c|M.tuberculosis_H37Rv MTLAEAADAINFG-----LAGRVVLVTGGVRGVGAGISSVFAEQGATVIT
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
MAB_0827|M.abscessus_ATCC_1997 MTSPLK--------------SRRAFVTGGSRGIGAGIVRRLAEDGARVVF
Mflv_2659|M.gilvum_PYR-GCK TGRGIAEDPA-----------WGTGIRVDHRDDDAVGRVFDRVGAEAGRL
Mvan_3919|M.vanbaalenii_PYR-1 TGRTVADAPA-----------WGTGVRVDHRDDDAVGALFERVGAEAGRL
MSMEG_2923|M.smegmatis_MC2_155 TGRTVTDPGP-----------GGVAVPVDHSDDVAVGALFRRVADESGRL
TH_1294|M.thermoresistible__bu TGRTVTDAD------------GVIPAPLDHADDSAVAALFDRVAAECGRL
MMAR_3513|M.marinum_M TSRSVADAPP-----------GGVAVRVDHRDDTATAALFERVQQESGRL
MUL_2755|M.ulcerans_Agy99 ------------------------------------------MQQESGRL
MAV_3035|M.avium_104 TSRTIADTPS-----------GVVPVRVDHRDDAAVSDLFDRVRRESGRL
Mb3579c|M.bovis_AF2122/97 CARRAVDG------------QPYEFHRCDIRDEDSVKRLVGEIGERHGRL
Rv3549c|M.tuberculosis_H37Rv CARRAVDG------------QPYEFHRCDIRDEDSVKRLVGEIGERHGRL
MLBr_01807|M.leprae_Br4923 THRASVVP------------DWFFGVECDVTDNDAIGAAFKAVEEHQGPV
MAB_0827|M.abscessus_ATCC_1997 TYSSSVQQAADVVDDINEDGGWARAVKADVADPDQLGAAIGQAAEELGGL
. * :
Mflv_2659|M.gilvum_PYR-GCK DLLVNNAAAISDNLVSAAPFWEKPRDLADVLTVGLRSSYIASWYAAPLLA
Mvan_3919|M.vanbaalenii_PYR-1 DLLVNNAAVISDDLVSPKPFWEKPRALADVLDVGLRSAYIASWHAAPLLT
MSMEG_2923|M.smegmatis_MC2_155 DLLVNNAAAIHDALVDPKPFWEKPIELADVLDVGLRSAYVASWHAAPLLL
TH_1294|M.thermoresistible__bu DLLVNNAAAVHPALTDPRPFWQKSVELADILDIGLRSAYVAAYHAAPLLL
MMAR_3513|M.marinum_M DLLVNNAAAISDDLVDPKPFWEKPLALADVLDVGLRSSYVASWYAAPLLV
MUL_2755|M.ulcerans_Agy99 DLLVNNAAAISDDLVDPKPFWEKPLALADVLDVGLRSSYVASWYAAPLLV
MAV_3035|M.avium_104 DLLVNNAATISDNLVSSKPFWEKPLDLADVLDVGLRSSYVASWYAAPLLV
Mb3579c|M.bovis_AF2122/97 DMLVNNAGGSPYALAAEATHNF----HRKIVELNVLAPLLVSQHANVLMQ
Rv3549c|M.tuberculosis_H37Rv DMLVNNAGGSPYALAAEATHNF----HRKIVELNVLAPLLVSQHANVLMQ
MLBr_01807|M.leprae_Br4923 EVLVANAGITSDMLIMRMSEEQ----FQKVIDVNLTGVFRVAKLASRNMI
MAB_0827|M.abscessus_ATCC_1997 DILVNNAGILSIGDVDTATLAD----FDEIVAVNVRAVFAGIKAASPHLT
::** **. . .:: :.: . * :
Mflv_2659|M.gilvum_PYR-GCK AQ--DRALIAFTSSPGSVCYMHGPAYGAQKAGVDKMAADMAVDFRGTGVA
Mvan_3919|M.vanbaalenii_PYR-1 AQ--QRGLVVFTSSPGSVCYMHGPAYGAQKAGVDKMAADMAVDFRGTGVS
MSMEG_2923|M.smegmatis_MC2_155 AG--DKGLIAFTSSPGSVCYMHGPAYGAQKAGVDKLAADMAVDFRGTSVC
TH_1294|M.thermoresistible__bu AA--DRALIAFTSSPGSVCYMHGPAYGAQKAGIDKMAADMAVDFRGTPVC
MMAR_3513|M.marinum_M AG--GRGLIAFTSSPGSVCYMHGPAYGAQKAGIDKMAADMAVDFHDTGVA
MUL_2755|M.ulcerans_Agy99 AG--GRGLIAFTSSPGSVCYMHGPAYGAQKAGIDKMAADMAVDFHDTGVA
MAV_3035|M.avium_104 AG--GRGLIAFTSSPGSVCYMHGPAYGAQKAGVDKMAADMAVDFRGTGVA
Mb3579c|M.bovis_AF2122/97 AQPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPK-VR
Rv3549c|M.tuberculosis_H37Rv AQPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPK-VR
MLBr_01807|M.leprae_Br4923 KQRFGRYIFMGSVVG-LSGVPGQANYAASKSGLIGMARSLARELGSRSIT
MAB_0827|M.abscessus_ATCC_1997 EG--GRIVTIGSINGDSSPTANLSLYSMTKAAVAGLTRGLAREFGPRGIT
: . *. *:.: :: :* : :
Mflv_2659|M.gilvum_PYR-GCK TVSVWMGILLTAKLRGAFDSDP---DALAAFAAHAETPEFTGHVIDALFR
Mvan_3919|M.vanbaalenii_PYR-1 AVSIWMGILLTDKLRSAFDGSP---EALAAFAEQAETPEFTGHVIDALFR
MSMEG_2923|M.smegmatis_MC2_155 TVSIWMGILLTEKLRAAFAGNP---EALAETAKHAETPEFTGRLIDALYR
TH_1294|M.thermoresistible__bu TVSIWMGILLTEQMRRAFTGRP---DALAAMAEHAETPEFTGHILDALYR
MMAR_3513|M.marinum_M TVSIWMGILLTEKLRGAFGQHPDGQLALAKTAEHAETPEFTGYLIDALYR
MUL_2755|M.ulcerans_Agy99 TVSIWMGILLTEKLRGAFGQHPDGQRTLAKTAEHAETPEFTGYLIGALYR
MAV_3035|M.avium_104 TVSIWMGILLTEKLRAAFGADP---AALAATAEHAETPEFTGYVIDALFD
Mb3579c|M.bovis_AF2122/97 VNAVVVGMVETERSELFYGDAES-----IARVAATVPLGRLARPADIGWA
Rv3549c|M.tuberculosis_H37Rv VNAVVVGMVETERSELFYGDAES-----IARVAATVPLGRLARPADIGWA
MLBr_01807|M.leprae_Br4923 ANVVAPGFIDTEMTRAMDSKYQE-----AALQA--IPLGRIGAVEEIAGA
MAB_0827|M.abscessus_ATCC_1997 INNVQPGPIGTDMN-PEDGQLAD-----ILRPN--IAVGRYGQPRDIASL
: * : * . .
Mflv_2659|M.gilvum_PYR-GCK DPGLADLSGHTVIGAELAARYGITDEGGRTPPSHRGMLGEPRTPSAVVVR
Mvan_3919|M.vanbaalenii_PYR-1 DPELDDVSGHTLIAAELATRYGITDEGGRTPPSHRQMLGAPREPSPVIIR
MSMEG_2923|M.smegmatis_MC2_155 DPQLGELSGQTVIGAELATRYGITDEGGRIPPSHREMLGAPRVAHPAVVR
TH_1294|M.thermoresistible__bu DPQLEQLSGHTLIGAELAERYNITDEGGRRPPSHRAMLGDPRPPSDVVVR
MMAR_3513|M.marinum_M DPALGELSGQTVIGAELAERYGITDEGGRRPPSHRHMLGAPRTPSTVVVR
MUL_2755|M.ulcerans_Agy99 DPALGELSGQTVIGAELAERYGITDEGGRRPPSHRHILGAPRTPSTVVVR
MAV_3035|M.avium_104 DPGLAELSGQTLIGAELAQRYGITDEGGRRPPSHRDMLGSPRTPSSVVVR
Mb3579c|M.bovis_AF2122/97 AAFLASDAASYISGATLEV------HGGGEPPPYLGASSANK--------
Rv3549c|M.tuberculosis_H37Rv AAFLASDAASYISGATLEV------HGGGEPPPYLGASSANK--------
MLBr_01807|M.leprae_Br4923 VSFLASEDAGYISGAVIPV------DGG------LGMGH-----------
MAB_0827|M.abscessus_ATCC_1997 VSYLVSDEAWYITGTAINI------DGG------FTA-------------
. * . . : .: : .**