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PSVTRKAQATRQERREQIERRLLEATDRLMADGASITELSVDRLASEAGISRASFYIYFEDKGHLLRRLA SQVFGDLADAAQRWWSVASRLDPEDVRVAMAAIIAAYRQHQPVLVALNEMAPYDPAVAETYRDLIAEIST RFEAVIVEGQKAGTIRPQLPPDITAHTLVLMVERTCQQNLPSRPTSFDTELADVLTEIVWGSLYLTNPAG *
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2639 | - | - | 100% (211) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0963 | - | 4e-11 | 28.57% (217) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1676 | - | 2e-05 | 33.64% (107) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3084c | - | 5e-10 | 27.39% (157) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3058c | - | 5e-10 | 27.39% (157) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_01070 | - | 5e-11 | 27.80% (205) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0314c | - | 7e-12 | 29.67% (182) | TetR family transcriptional regulator |
| M. marinum M | MMAR_3762 | - | 7e-80 | 69.71% (208) | AcrR family transcriptional regulator |
| M. avium 104 | MAV_1733 | - | 9e-76 | 65.12% (215) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_4622 | - | 9e-83 | 73.30% (206) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2600 | - | 1e-13 | 27.59% (203) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_3708 | - | 1e-79 | 69.23% (208) | AcrR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0955 | - | 2e-10 | 28.57% (203) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3762|M.marinum_M -MASITRNA----QANRRQRREQM----ECRLLEATERLMNNGASFTELS
MUL_3708|M.ulcerans_Agy99 -MASITRNA----QANRRQRREQM----ECRLLEATERLMNNGASFTELS
MAV_1733|M.avium_104 -MPSVTRTPPGRRSPGREQRREQL----ERRLLDATERLMRDGASFTELS
MSMEG_4622|M.smegmatis_MC2_155 -MPSVTRKP----QANREERRERI----ERALLDATDRLMSDGTSFTELS
Mflv_2639|M.gilvum_PYR-GCK -MPSVTRKA----QATRQERREQI----ERRLLEATDRLMADGASITELS
Mb3084c|M.bovis_AF2122/97 -MTSHAADE--KQAAPPMRRRGDR----HRQAILRAARELLEETPFAELS
Rv3058c|M.tuberculosis_H37Rv -MTSHAADE--KQAAPPMRRRGDR----HRQAILRAARELLEETPFAELS
MAB_0314c|M.abscessus_ATCC_199 ---------------------------------MDAARVVISRVGYAETR
MLBr_01070|M.leprae_Br4923 MIVVGNFTQSNYVPASRGRRSSQLSGDDREQAILAVAERLLAERPLGDFS
TH_2600|M.thermoresistible__bu -MSKPRVRN----RYSSGPTRGEQ----RRERLLQALEDLLASRPFAAIE
Mvan_0955|M.vanbaalenii_PYR-1 -MTSDVASR--LRRAPRQERSRAM-----VDRILDAGEQMLIAHGFDGAS
. . :
MMAR_3762|M.marinum_M VDRLATEAGISRASFYIYFDDKGHLLRRLAGQVFDDLATGAQHWWDVAWR
MUL_3708|M.ulcerans_Agy99 VDRLATEAGISRASFYIYFDDKGHLLRRLAGQVFDDLATGAQHWWDVAWR
MAV_1733|M.avium_104 VDRLAGAAGISRASFYIYFEDKGHLLRRLASRVFGELTDGARRWWSVAGR
MSMEG_4622|M.smegmatis_MC2_155 VDRLATEAGISRASFYIYFEDKGHLLRRLAAQVFDDLAHEAQQWWGVAGR
Mflv_2639|M.gilvum_PYR-GCK VDRLASEAGISRASFYIYFEDKGHLLRRLASQVFGDLADAAQRWWSVASR
Mb3084c|M.bovis_AF2122/97 VRAISLRAGVARSGFYFYFDSKYSVLAQILAEATEELEEASQHFSARQPG
Rv3058c|M.tuberculosis_H37Rv VRAISLRAGVARSGFYFYFDSKYSVLAQILAEATEELEEASQHFSARQPG
MAB_0314c|M.abscessus_ATCC_199 VIDITTEAGKSVGVFYNYFTDKAELLRTMVDEFRDDAYARGDTVATSD--
MLBr_01070|M.leprae_Br4923 VDELAKGAGISRPTFYFYFPSKNAVLLSLLDDLNMKSRSAVEALAEQLP-
TH_2600|M.thermoresistible__bu VGDIARAAGLSRSAFYFYFPSKAAAVGAMLGDVFGEISDVLDKWTELGDS
Mvan_0955|M.vanbaalenii_PYR-1 TNRIAAAAGISPGSLYQYFPNKDAIAAAVIDRFSDQLSARVAARVSERLD
. :: ** : :* ** .* : .
MMAR_3762|M.marinum_M HDPDD--VRAAMRAIIARYRRHQPILIALNEMAGYDPQTAQTYRDILTAI
MUL_3708|M.ulcerans_Agy99 HDPDD--VRAAMCAIIARYRRHQPILIALNEMAGYEPQTAQTYRDILTAI
MAV_1733|M.avium_104 HDPDD--VRAAMTRIIATYRRHQAVLVALNEMSGYDPLTAQTYREILTGI
MSMEG_4622|M.smegmatis_MC2_155 RNPGD--VHTAMSGIIASYRRHQPVLVALNEMSAYDPLVAQTYRDLLTGI
Mflv_2639|M.gilvum_PYR-GCK LDPED--VRVAMAAIIAAYRQHQPVLVALNEMAPYDPAVAETYRDLIAEI
Mb3084c|M.bovis_AF2122/97 ESPEQF-VNRMIGSVAAVYANNDPVLRACNAARQSDMEIRDILERQFQVL
Rv3058c|M.tuberculosis_H37Rv ESPEQF-VNRMIGSVAAVYANNDPVLRACNAARQSDMEIRDILERQFQVL
MAB_0314c|M.abscessus_ATCC_199 RPPHEV-IRDIVTVYWTTYREHAPVLSGVFQAAQVDPTFVDYWRNLRAPA
MLBr_01070|M.leprae_Br4923 ADPAAV-WRSAITAFFEVCGTHRAVAVAGAAAKATSPEVRRLWSTVMQQW
TH_2600|M.thermoresistible__bu VAARRREVYDSFERVVAIWRQHAPLMAAMFDAASTDAEVRAMFEGHIDSF
Mvan_0955|M.vanbaalenii_PYR-1 QPAPDY-VRESIAALIEALDVHPEFLRAVMEQTPR--LGTGSKLVAFEQR
. . : . .
MMAR_3762|M.marinum_M SARLARVIEDGQADG---SIRPELSATTTANALTWMVERTCHQNLPSR--
MUL_3708|M.ulcerans_Agy99 SARLARVIEDGQADG---SIRPELSATTTANALTWMVERTCHQNLPSR--
MAV_1733|M.avium_104 SGQLTRVIEDGQADG---SIRPRLAAATTASALTWMVERACQQNLPAQ--
MSMEG_4622|M.smegmatis_MC2_155 SAQLARVIDEGQADG---SIRAQLPAETTASTLTWMVERTCHQNLPSR--
Mflv_2639|M.gilvum_PYR-GCK STRFEAVIVEGQKAG---TIRPQLPPDITAHTLVLMVERTCQQNLPSR--
Mb3084c|M.bovis_AF2122/97 LRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALMLTGDALLVG---
Rv3058c|M.tuberculosis_H37Rv LRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALMLTGDALLVG---
MAB_0314c|M.abscessus_ATCC_199 RTMIANNIRHLQARG----YCPGMDPDITASAIGAMLDYFCYVWLVEGGE
MLBr_01070|M.leprae_Br4923 IDYNTAAIQAERKCG---VAPDTIPAEDLAVALQLMTERVMAATFSDE--
TH_2600|M.thermoresistible__bu VDGSAARIRHERAVG---EAPDGPDPEALARVLVGMNVKALERDMRAITS
Mvan_0955|M.vanbaalenii_PYR-1 IGELTVAYLTINKRQ----VRTDVTVDVAAWMLVRMVEHLCVRYILDQ--
: :
MMAR_3762|M.marinum_M ---PPEFDAELADTLSEIVWGALYLTSTSLR-------
MUL_3708|M.ulcerans_Agy99 ---PPEFDAELADTLSEIVWGALYLTSTSLR-------
MAV_1733|M.avium_104 ---PSAYDAELADTLAEIVWGALYLKPASGS-------
MSMEG_4622|M.smegmatis_MC2_155 ---PASYDAELADTLTEIVWGALYLRPASTDR------
Mflv_2639|M.gilvum_PYR-GCK ---PTSFDTELADVLTEIVWGSLYLTNPAG--------
Mb3084c|M.bovis_AF2122/97 ---PDSDAARRVRVLEQMWLNALWGGGKAP--------
Rv3058c|M.tuberculosis_H37Rv ---PDSDAARRVRVLEQMWLNALWGGGKAP--------
MAB_0314c|M.abscessus_ATCC_199 RGRSAVTDEEAIDTLARIWFNALWWKSEGAHGAT----
MLBr_01070|M.leprae_Br4923 --KPLIPDKKVIDTLVHIWLASIYGS------------
TH_2600|M.thermoresistible__bu ---GAPADADLPRVLAFVWGRVLYDA------------
Mvan_0955|M.vanbaalenii_PYR-1 ---PSIEREKFIDEVTLMALNYLRPWPTPPEDCFGSPR
: : :