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M. tuberculosis H37Rv Rv3058c (-)

annotation: POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY)
coordinates: 3418726 - 3419376
length: 216

TSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSKYSVLAQ
ILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAARQSDMEIRDILERQFQV
LLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALMLTGDALLVGPDSDAARRVRVLEQMWLNALWG
GGKAP*

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. tuberculosis H37Rv Rv3058c - - 100% (216) POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY)
M. tuberculosis H37Rv Rv3855 ethR 1e-16 29.28% (222) transcriptional regulatory repressor protein (TETR-family)
M. tuberculosis H37Rv Rv0302 - 3e-05 25.48% (208) TetR/ACRR family transcriptional regulator

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb3084c - 1e-119 100.00% (216) TetR family transcriptional regulator
M. gilvum PYR-GCK Mflv_4314 - 2e-53 52.79% (197) TetR family transcriptional regulator
M. leprae Br4923 MLBr_01070 - 2e-13 27.18% (195) putative TetR-family transcriptional regulator
M. abscessus ATCC 19977 MAB_3422c - 5e-49 50.26% (195) TetR family transcriptional regulator
M. marinum M MMAR_1635 - 2e-89 75.00% (212) TetR family transcriptional regulator
M. avium 104 MAV_3926 - 3e-83 69.81% (212) transcriptional regulator, TetR family protein
M. smegmatis MC2 155 MSMEG_2290 - 1e-59 57.43% (202) transcriptional regulator, TetR family protein
M. thermoresistible (build 8) TH_1635 - 2e-58 54.07% (209) transcriptional regulator, TetR family protein
M. ulcerans Agy99 MUL_3401 - 1e-89 75.00% (212) TetR family transcriptional regulator
M. vanbaalenii PYR-1 Mvan_2032 - 2e-54 53.81% (197) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Rv3058c|M.tuberculosis_H37Rv        -------MTSHAADEKQ-------AAPPMRRRGDRHRQAILRAARELLEE
Mb3084c|M.bovis_AF2122/97           -------MTSHAADEKQ-------AAPPMRRRGDRHRQAILRAARELLEE
MMAR_1635|M.marinum_M               ------MVNGQAADEKQ-------RGPTLRRRGDKQRQAILQAVRELLEE
MUL_3401|M.ulcerans_Agy99           ------MVNGQAADEKQ-------RGPTLRRRGDKQRQAILQAVRELLEE
MAV_3926|M.avium_104                -------MTSHPANPE----------PGARRRGDKQRQAILAAVRELLQE
MSMEG_2290|M.smegmatis_MC2_155      -------MTAESVPQGSNGSAGATAAQARRSRGDRQREAIVAAVRELLEE
TH_1635|M.thermoresistible__bu      -------VTTDSP-----------AREDRRSRGDRQRDAIVAAVRELLEE
Mflv_4314|M.gilvum_PYR-GCK          -MPRSNSMTAEPAP-----------TDLRRSRGDRQRDAIVTAVRELLHE
Mvan_2032|M.vanbaalenii_PYR-1       -------MTAEPAP-----------SDLRRSRGDRQRDAIIAAVRELLQE
MAB_3422c|M.abscessus_ATCC_199      -------MVSPARS-------------GTQTRGDRQRDAIMTAVAELIAE
MLBr_01070|M.leprae_Br4923          MIVVGNFTQSNYVPASR-------GRRSSQLSGDDREQAILAVAERLLAE
                                                                 :  ** :.:**: .. .*: *

Rv3058c|M.tuberculosis_H37Rv        -TPFAELSVRAISLRAGVARSGFYFYFDSKYSVLAQILAEATEELEEASQ
Mb3084c|M.bovis_AF2122/97           -TPFAELSVRAISLRAGVARSGFYFYFDSKYSVLAQILAEATEELEEASQ
MMAR_1635|M.marinum_M               -RPFAELSVATISNRAGVARSGFYFYFDSKYSVLAQLMAEAVEELEERTQ
MUL_3401|M.ulcerans_Agy99           -RPFAELSVATISNRAGVARSGFYFYFDSKYSVLAQLMAEAVEELEERTQ
MAV_3926|M.avium_104                -KPFAELSVSTISLRAGVARSGFYFYFDSKYAVLAQLMAEATEELEQLTQ
MSMEG_2290|M.smegmatis_MC2_155      -QPFADISVSTISERAGVARSGFYFYFDSKYAVLAVILAEAMEELDALTH
TH_1635|M.thermoresistible__bu      -RSFADLSVSTISERAGVARSGFYFYFDSKYAVLAVILGEAMEELDKLTQ
Mflv_4314|M.gilvum_PYR-GCK          -RPFAELSVSTISERAGVARSGFYFYFDSKYAVLAVIIAEAMAELDQLTH
Mvan_2032|M.vanbaalenii_PYR-1       -RAFADLSVSTISERAGVARSGFYFYFDSKYAVLAVIVAEAMAELDQLTH
MAB_3422c|M.abscessus_ATCC_199      NHSFADLSVSAISERAGVGRSGFYFYFDSKYSVLAQMVGDAFAELDELTH
MLBr_01070|M.leprae_Br4923          -RPLGDFSVDELAKGAGISRPTFYFYFPSKNAVLLSLLDDLNMKSRSAVE
                                      .:.::**  ::  **:.*. ***** ** :**  :: :   :     .

Rv3058c|M.tuberculosis_H37Rv        HFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAARQSDMEIRDIL
Mb3084c|M.bovis_AF2122/97           HFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAARQSDMEIRDIL
MMAR_1635|M.marinum_M               YFAPRQPGESPQEFAKRMVGSAAIVYTHNDPVMMACNAARHTDIEIRDIL
MUL_3401|M.ulcerans_Agy99           YFAPRQPGESPQEFAKRMVGSAAIVYTHNDPVMMACNAARHTDIEIRDIL
MAV_3926|M.avium_104                YFAPRQPGESPEQFAKRMVGSAAAVYAHNDPVMTACNEARHTDVEIRNLM
MSMEG_2290|M.smegmatis_MC2_155      NFAPRGENESPAAFAKRMVGSAAAVYATNDPVMSACTVAQNTDAQIRDIM
TH_1635|M.thermoresistible__bu      NFAPRGAEETPAEFARRMVGSAAAVYASNDPVMRACSAAQNTDAQIREMM
Mflv_4314|M.gilvum_PYR-GCK          SFGPRDEAESPSEFAKRMVGYAAIVFASNDPIMRACNLARSTDAQIREIM
Mvan_2032|M.vanbaalenii_PYR-1       DFAPREPGESPSDFAKRMVGYAATVYARNDPIMGACNLARNTDAEIREIM
MAB_3422c|M.abscessus_ATCC_199      YFAPRGEEETPEQFAHRMVGSAAASFAHNDPLMKACQEARITDPTIAGLL
MLBr_01070|M.leprae_Br4923          ALAEQLPAD-PAAVWRSAITAFFEVCGTHRAVAVAGAAAKATSPEVRRLW
                                     :. :   : *  . .  :         : .:  *   *: :.  :  : 

Rv3058c|M.tuberculosis_H37Rv        ERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALMLTGDA
Mb3084c|M.bovis_AF2122/97           ERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALMLTGDA
MMAR_1635|M.marinum_M               DQQFDVVLREIVGVIDAEMRAGTANPISEDLPTLIRTLTATTALMLTGDA
MUL_3401|M.ulcerans_Agy99           DQQFDVVLREIVGVIDAEMRAGTANPISEDLPTLIRTLTATTALMLTGDA
MAV_3926|M.avium_104                DQQFEVVLAQIVGIVEAEMKAGTARPISDDLPTLIRTLAGTTALMLTGDP
MSMEG_2290|M.smegmatis_MC2_155      NDFEDATIAKIVGVIE---QDTGARPISDDLPALVRTLTATTAMTLSRDA
TH_1635|M.thermoresistible__bu      GDLQAIVIDKIVGVIE---QDASAQPITDDLHALVRTLVATTALTLTHDS
Mflv_4314|M.gilvum_PYR-GCK          DDFQNTVVEKIVGLVG---RDAGARPISDDLPALVRVMIAVTSSTLAHDS
Mvan_2032|M.vanbaalenii_PYR-1       DDFQDSVIDKIVDLVG---RDSGARPVSQDLPALVRTLIAMTSMTLAHDS
MAB_3422c|M.abscessus_ATCC_199      DDLTDVVIEKILKIAETEVKERGAQPISDDLPALVRSLVALTASTVSGDS
MLBr_01070|M.leprae_Br4923          STVMQQWIDYNTAAIQAE-RKCGVAPDTIPAEDLAVALQLMTERVMAATF
                                           :           :   . * :     *   :   *   ::   

Rv3058c|M.tuberculosis_H37Rv        LLVGPDSDAARRVRVLEQMWLNALWGGGKAP----
Mb3084c|M.bovis_AF2122/97           LLVGPDSDAARRVRVLEQMWLNALWGGGKAP----
MMAR_1635|M.marinum_M               LLVGRDSDLERRVRVLEQMWLNALWGGPIRT----
MUL_3401|M.ulcerans_Agy99           LLVGRDSDLERRVRVLEQMWLNALWGGPIRT----
MAV_3926|M.avium_104                VLTGPDSDRDRRVAVLEQLWLHALWAG--RP----
MSMEG_2290|M.smegmatis_MC2_155      GFVGRDADPARAVEIVERLWLSALWGG--LPE---
TH_1635|M.thermoresistible__bu      AFVGRATDISRAVDVVERLWLYSLWGGGNLPER--
Mflv_4314|M.gilvum_PYR-GCK          AFVGRDGDPARALAVVERLWESSLWGGQ-------
Mvan_2032|M.vanbaalenii_PYR-1       AFVGRGADPARAVEIVERLWLSSLWGGDSLETHKA
MAB_3422c|M.abscessus_ATCC_199      SFVGRNTDPARAIATVETLWRVSLLGR--------
MLBr_01070|M.leprae_Br4923          SDEKPLIPDKKVIDTLVHIWLASIYGS--------
                                              : :  :  :*  :: .

species	id	gene	e-value	identity (len)	annotation
M. tuberculosis H37Rv	Rv3058c	-	-	100% (216)	POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY)
M. tuberculosis H37Rv	Rv3855	ethR	1e-16	29.28% (222)	transcriptional regulatory repressor protein (TETR-family)
M. tuberculosis H37Rv	Rv0302	-	3e-05	25.48% (208)	TetR/ACRR family transcriptional regulator