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M. thermoresistible (build 8) TH_2600 (-)

annotation: putative transcriptional regulator, TetR family
coordinates: 4300312 - 4300947
length: 212

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2600--100% (212)putative transcriptional regulator, TetR family
M. thermoresistible (build 8)TH_3269-3e-2738.69% (168) PUTATIVE transcriptional regulator, TetR family
M. thermoresistible (build 8)TH_1150-1e-2033.65% (208) TRANSCRIPTIONAL REGULATORY REPRESSOR PROTEIN (TETR-FAMILY) ETHR

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3885ethR5e-1429.06% (203) transcriptional regulatory repressor protein (TETR-family)
M. gilvum PYR-GCKMflv_3103-4e-2433.67% (199) TetR family transcriptional regulator
M. tuberculosis H37RvRv3855ethR5e-1429.06% (203) transcriptional regulatory repressor protein (TETR-family)
M. leprae Br4923MLBr_01070-6e-1732.58% (178) putative TetR-family transcriptional regulator
M. abscessus ATCC 19977MAB_3422c-4e-1427.59% (174) TetR family transcriptional regulator
M. marinum MMMAR_5405ethR6e-1630.73% (205) TetR family transcriptional regulator
M. avium 104MAV_0173-2e-2032.52% (206) transcriptional regulator, TetR family protein
M. smegmatis MC2 155MSMEG_3874-2e-2338.10% (168) transcriptional regulator, TetR family protein
M. ulcerans Agy99MUL_5027ethR4e-1630.92% (207) TetR family transcriptional regulator
M. vanbaalenii PYR-1Mvan_3432-1e-1932.74% (168) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3103|M.gilvum_PYR-GCK          -------------MRSPTDRRQPQKSDLRRVAILESLNHHLRE-SGFDAL
Mvan_3432|M.vanbaalenii_PYR-1       -------MQRGLPVRSPTDRRQPQKSDLRRSAILESLDQHLRE-SGFDGL
MSMEG_3874|M.smegmatis_MC2_155      ------MVRPSTPVRSPTDRRQPQRSDLRRTAILEALNEHLQK-TGFDAL
TH_2600|M.thermoresistible__bu      ---------MSKPRVRNRYSSGPTRGEQRRERLLQALEDLLAS-RPFAAI
Mb3885|M.bovis_AF2122/97            ----MTTSAASQASLPRGRRTARPSGDDRELAILATAENLLED-RPLADI
Rv3855|M.tuberculosis_H37Rv         ----MTTSAASQASLPRGRRTARPSGDDRELAILATAENLLED-RPLADI
MMAR_5405|M.marinum_M               ---MVSTSTASQASPSRGRRSARPSGDERELAILNTAEKLLED-RPMVDI
MUL_5027|M.ulcerans_Agy99           ----MSTSTASQASLSRGRRSARPSGDERELAILNTAEKLLED-RPMVDI
MAV_0173|M.avium_104                ------MTTAGQTRALRGRRAIRPTGDEREQAILATALRLLET-RPFAGI
MLBr_01070|M.leprae_Br4923          MIVVGNFTQSNYVPASRGRRSSQLSGDDREQAILAVAERLLAE-RPLGDF
MAB_3422c|M.abscessus_ATCC_199      -------------MVSPARSGTQTRGDRQRDAIMTAVAELIAENHSFADL
                                                             .: :.  ::      :     :  :

Mflv_3103|M.gilvum_PYR-GCK          NIAAVAKRAGVTRSAFYFYFENKAAAVAALLEPMYDDGFLASDILTDTTQ
Mvan_3432|M.vanbaalenii_PYR-1       NIADVTRRAGVTRSAFYFYFENKAAAVAALLEPMYDDGFLAGDLLANIEQ
MSMEG_3874|M.smegmatis_MC2_155      NIAEVARQAGVGRSAFYFYFENKAAAVAALLEPMHEALLAANNILADLTR
TH_2600|M.thermoresistible__bu      EVGDIARAAGLSRSAFYFYFPSKAAAVGAMLGDVFGEISDVLDKWTELGD
Mb3885|M.bovis_AF2122/97            SVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPA
Rv3855|M.tuberculosis_H37Rv         SVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPA
MMAR_5405|M.marinum_M               SVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNEADAALDNLAQAP-
MUL_5027|M.ulcerans_Agy99           SVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNEADAALDNLAQAP-
MAV_0173|M.avium_104                SVDDLAKGAGLSRPTFYFYFKSKEAVVLSLLEPVIARADAEFDGAVQRL-
MLBr_01070|M.leprae_Br4923          SVDELAKGAGISRPTFYFYFPSKNAVLLSLLDDLNMKSRSAVEALAEQL-
MAB_3422c|M.abscessus_ATCC_199      SVSAISERAGVGRSGFYFYFDSKYSVLAQMVGDAFAELDELTHYFAPRGE
                                    .:  ::. **: *. ***** .* :.:  ::           .  .    

Mflv_3103|M.gilvum_PYR-GCK          PPARRVR---AMLEALLDTVDEHRYLLQAMLEARATSAAIRHVWDEARET
Mvan_3432|M.vanbaalenii_PYR-1       PPRARIR---AMLEALLDTVDQHRYLLQAMLEARASSTVIREVWDDARES
MSMEG_3874|M.smegmatis_MC2_155      PPGERIR---ATLDAVLRTAEDHRYLFQAMLEARGTSGAVRDMWDAARES
TH_2600|M.thermoresistible__bu      SVAARRREVYDSFERVVAIWRQHAPLMAAMFDAASTDAEVRAMFEGHIDS
Mb3885|M.bovis_AF2122/97            DTDRENMWR-TGINVFFETFGSHKAVTRAGQAARATSVEVAELWSTFMQK
Rv3855|M.tuberculosis_H37Rv         DTDRENMWR-TGINVFFETFGSHKAVTRAGQAARATSVEVAELWSTFMQK
MMAR_5405|M.marinum_M               DVDHVTMWR-NGINVFFETFGSHRAVVQGGQGVRSISAEVRELWSTFMQK
MUL_5027|M.ulcerans_Agy99           DVDHVTMWR-NGINVFFETFGSHRAVVQGGQGVRSISTEVRELWSTFMQK
MAV_0173|M.avium_104                PTDPRRVWR-NGIKAFFTAFSSHRALARAATEALATSSELRSVWSGFMQK
MLBr_01070|M.leprae_Br4923          PADPAAVWR-SAITAFFEVCGTHRAVAVAGAAAKATSPEVRRLWSTVMQQ
MAB_3422c|M.abscessus_ATCC_199      EETPEQFAH-RMVGSAAASFAHNDPLMKACQEARITDPTIAGLLDDLTDV
                                                .         :  :  .   .   .  :  : .   : 

Mflv_3103|M.gilvum_PYR-GCK          FVPTVAQMIASER-AAGRAPDGPGPEMIAGILLEFNDRLMER---HTLGG
Mvan_3432|M.vanbaalenii_PYR-1       FVPTVARMITAER-DSGRAPAGSSAEVVASMLLEFNDRLMER---HTLGG
MSMEG_3874|M.smegmatis_MC2_155      FVPTVSAVITAER-ESGRAPDGVDPKVLASLLMEFNDRLLER---LIIGG
TH_2600|M.thermoresistible__bu      FVDGSAARIRHER-AVGEAPDGPDPEALARVLVGMNVKALERDMRAITSG
Mb3885|M.bovis_AF2122/97            WIAYTAAVIDAER-DRGAAPRTLPAHELATALNLMNERTLFAS-FAGEQP
Rv3855|M.tuberculosis_H37Rv         WIAYTAAVIDAER-DRGAAPRTLPAHELATALNLMNERTLFAS-FAGEQP
MMAR_5405|M.marinum_M               WIAYTAKIIEAER-ERGAAPVTLPALELATALNLMNERTLSAS-FLAEEP
MUL_5027|M.ulcerans_Agy99           WIAYTAKIIEAER-ERGAAPVTLPALELATALNLMNERTLSAS-FLAEEP
MAV_0173|M.avium_104                WIDQTAAMITAER-ERGAAPDTIPAADLATSLNQMNERTMMAA-LSAETP
MLBr_01070|M.leprae_Br4923          WIDYNTAAIQAER-KCGVAPDTIPAEDLAVALQLMTERVMAAT-FSDEKP
MAB_3422c|M.abscessus_ATCC_199      VIEKILKIAETEVKERGAQPISDDLPALVRSLVALTASTVSGD-SSFVGR
                                     :         *    *  *       :.  *  :.   :          

Mflv_3103|M.gilvum_PYR-GCK          RLSRDELLTAAQSVWLRTIYANDGDELQ
Mvan_3432|M.vanbaalenii_PYR-1       RLGRDELLAGAETIWLRTIYAHDGDL--
MSMEG_3874|M.smegmatis_MC2_155      PLTRRQLLEGAEAMWMGAIYASEPEQTR
TH_2600|M.thermoresistible__bu      APADADLPRVLAFVWGRVLYDA------
Mb3885|M.bovis_AF2122/97            SVPEARVLDTLVHIWVTSIYGENR----
Rv3855|M.tuberculosis_H37Rv         SVPEARVLDTLVHIWVTSIYGENR----
MMAR_5405|M.marinum_M               SVPETHVVDTLVHIWVSSIYGEAR----
MUL_5027|M.ulcerans_Agy99           SVPETHVVDTLVHVWVSSIYGAAR----
MAV_0173|M.avium_104                AVAEDRVVDTLTHIWVSSIYGESG----
MLBr_01070|M.leprae_Br4923          LIPDKKVIDTLVHIWLASIYGS------
MAB_3422c|M.abscessus_ATCC_199      NTDPARAIATVETLWRVSLLGR------
                                                 :*   :