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MVRPAQTVRSERTREALRQAAVVRFLAQGVEETTAEQIAADAGVSLRTFYRHFASKHDLLFADYDAGLHW FRAALATRSPEDPILDTVQAAIMAAPYDDWAVTKIAAMRSQELDAGRIVRHIRQVEADFADAIDEHLARA DGASPGTDERMRTTVTARCIAAAVFGAMEVWMLGEDSSLPELDRLCRHALDLLRTGIADPA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1676 | - | - | 100% (201) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_5062 | - | 1e-12 | 28.50% (207) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0350 | - | 5e-08 | 41.89% (74) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3860c | - | 9e-73 | 70.00% (200) | transcriptional regulatory protein TetR-family |
| M. tuberculosis H37Rv | Rv3830c | - | 9e-73 | 70.00% (200) | transcriptional regulatory protein TetR-family |
| M. leprae Br4923 | MLBr_02568 | - | 3e-05 | 27.06% (170) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3837 | - | 1e-11 | 24.29% (177) | transcriptional regulatory protein TetR |
| M. marinum M | MMAR_5384 | - | 2e-73 | 71.08% (204) | TetR family transcriptional regulator |
| M. avium 104 | MAV_0197 | - | 2e-75 | 72.14% (201) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_1420 | - | 2e-10 | 27.01% (174) | transcriptional regulatory protein |
| M. thermoresistible (build 8) | TH_3524 | - | 7e-15 | 33.51% (191) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_5004 | - | 6e-73 | 70.59% (204) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5077 | - | 1e-96 | 85.00% (200) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1676|M.gilvum_PYR-GCK -MVRPAQTVRS-ERTREALRQAAVVRFLAQGVEETTAEQIAADAGVSLRT
Mvan_5077|M.vanbaalenii_PYR-1 -MVRPAQTARS-ERTREALRQAAVVRFLAQGVEDTSAEQIAADAGVSLRT
Mb3860c|M.bovis_AF2122/97 -MVRPPQTARS-ERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRT
Rv3830c|M.tuberculosis_H37Rv -MVRPPQTARS-ERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRT
MAV_0197|M.avium_104 -MVRPAQTARS-ERTREALRQAALVRFLAQGVEDTSAEQIAADAGVSLRT
MMAR_5384|M.marinum_M -MVRPAQTVRS-ERTREALRQAAVVRFLAQGVEETSAEQIAADAGVSLRT
MUL_5004|M.ulcerans_Agy99 -MVRPAQTVRS-ERTREALRQAAVVRFLAQGVEETSAEQIAADAGVSLRT
MAB_3837|M.abscessus_ATCC_1997 MNAQPARVGRRPSTTRDEITAVAMTLFAQHGFDEVSVDDIAAAAGIARRT
MSMEG_1420|M.smegmatis_MC2_155 -MSEGSRAGRRRSTTQDHIAGVAIDLFAARGFDAVSVDDVAAAAGISRRT
TH_3524|M.thermoresistible__bu --------VRG-HRNREALIAAAIDLFTVNGYEQTTVEQIAEAAGVAPRT
MLBr_02568|M.leprae_Br4923 -MAGGAKRIPR-AVREQQMLDAAVQMFSVNGYHKTSMDAIAAEAQISKPM
.: : .*: * .* . .: : :* * ::
Mflv_1676|M.gilvum_PYR-GCK FYRHFASKHDLLFADYDAGLHWFRAALATR-SPEDPILDTVQAAIMAAP-
Mvan_5077|M.vanbaalenii_PYR-1 FYRHFASKHDLLFADYDAGLHWFRSALAAR-SPEESIFESVQSAIMASP-
Mb3860c|M.bovis_AF2122/97 FYRHFRSKHDLLFADYDAGLHWFRAALDAR-PADESIIDSVQAAIFSFP-
Rv3830c|M.tuberculosis_H37Rv FYRHFRSKHDLLFADYDAGLHWFRAALDAR-PADESIIDSVQAAIFSFP-
MAV_0197|M.avium_104 FYRHFRSKHDLLFADY-TGLHWFRAALDAR-PADEPIIDSVQAAIFSFP-
MMAR_5384|M.marinum_M FYRHFRSKHDLLFADY-TGLHWFRAALDAR-PVDETIIDSVQTAIFAFP-
MUL_5004|M.ulcerans_Agy99 FYRHFRSKHDLLFADY-TGLHWFRAALDAR-PVDEAIIDSVQTAIFAFP-
MAB_3837|M.abscessus_ATCC_1997 VFRYYSSKNAIVWGDFDSHLGVMRALLDET-ADTVDTSTALRQAVLTFND
MSMEG_1420|M.smegmatis_MC2_155 LFRYYASKSAIPWGDFDSHLQHLQNLLRTL-SSEVSLGDALREALLTFNT
TH_3524|M.thermoresistible__bu FFRHFAAKEDILFHGYADRLAEATRRFRAA-RSG-SLWKALAEASEAVAT
MLBr_02568|M.leprae_Br4923 LYLYYGSKEDLFGACLNREMSRFIAMVRADIDFTQSPKDLLRNTIVSFLR
.: :: :* : : . : : :
Mflv_1676|M.gilvum_PYR-GCK YDDWAVTKIAAMRSQELDAGRIVRHIRQVEADFADAIDEHLARADGASPG
Mvan_5077|M.vanbaalenii_PYR-1 YEDWAVTKIAAMRAKELDTGRIVRHIRQVEADFAEAVEQHMAAAGAAAPG
Mb3860c|M.bovis_AF2122/97 YDVDAVTKIASLRRGELEPSRIVRHMREVEADFADAIQAQLRRRNCDIAG
Rv3830c|M.tuberculosis_H37Rv YDVDAVTKIASLRRGELEPSRIVRHMREVEADFADAIQAQLRRRNCDIAG
MAV_0197|M.avium_104 YDVDAVTKIAALRHEELDPGRIVRHIRDVQADFAEAIAAQLQRRGRG-AG
MMAR_5384|M.marinum_M YDVEAVAKIATLRGGELDPSRIVRHIQEVQADFAEVIAAQLRRRSCAAAG
MUL_5004|M.ulcerans_Agy99 YDVEAVAKIATLRGGELDPSRIVRHIQEVQADFAEVIAAQLLRRSCAAAG
MAB_3837|M.abscessus_ATCC_1997 FPVDETPRHRMRMRMILEVPALQAYSMLMYTGWRDVIAQFVARRSGTDP-
MSMEG_1420|M.smegmatis_MC2_155 YADHEMAEHRQRMRVILETEELQAYSMTMYAGWRTVIAEYVADRLGMST-
TH_3524|M.thermoresistible__bu AIAENPGIFLVRARMYGELPALRATMLRINDDWIDQMTTEVARWLGSDAA
MLBr_02568|M.leprae_Br4923 YIDANRASWIVMYIQAMSLPAFAQTVREARDQITELVAGLMRVGTRS---
. : : :
Mflv_1676|M.gilvum_PYR-GCK TD-----ERMRTTVTARCIAAAVFGAMEVWMLGEDSSLPELDRLCRHALD
Mvan_5077|M.vanbaalenii_PYR-1 TD-----ERMRTTVTARCIAAAVFGAMEVWMLGEDRSLPELDRLCRQALT
Mb3860c|M.bovis_AF2122/97 AP----DARLHIAVTARCVAAAVFGAMEAWMLGSDRSLGELARVCHVALE
Rv3830c|M.tuberculosis_H37Rv AP----DARLHIAVTARCVAAAVFGAMEAWMLGSDRSLGELARVCHVALE
MAV_0197|M.avium_104 APTA--DQRVRAAVTARCIAAAVFGAMEVWMVGDERSLGELARLCHAALE
MMAR_5384|M.marinum_M TSAQTPDARVRTAVTARCIAAAVFGAMEVWMLGEDRSLGELARVCQLALE
MUL_5004|M.ulcerans_Agy99 TSAQTPDARVRTAVTARCIAAAVFGAMEVWMLGEDRSLGELARVCQLALE
MAB_3837|M.abscessus_ATCC_1997 -------GSLLPQTVAWTLLGVALAAYEQWLADESS---KLTTLLGKGFD
MSMEG_1420|M.smegmatis_MC2_155 -------TDLMPQTVAWLMLGVALSAYENWLADESV---SLRGAIAAAFE
TH_3524|M.thermoresistible__bu VD-------VRPRLAATVINGANRTAIDLWVSADGK--GDLVELMADAVR
MLBr_02568|M.leprae_Br4923 ---------SRPDHEYEIMAGALVGAGEAMATRLTTGDIAVDEAAELMIN
: .. * : : .
Mflv_1676|M.gilvum_PYR-GCK LLRTGIADPA----------------
Mvan_5077|M.vanbaalenii_PYR-1 LLRSGIEDPVG---------------
Mb3860c|M.bovis_AF2122/97 SLRVGISDTWTTLT---VSS------
Rv3830c|M.tuberculosis_H37Rv SLRVGISDTWTTLT---VSS------
MAV_0197|M.avium_104 SLRAGITDSWSTATAPQVSS------
MMAR_5384|M.marinum_M TLRAGLTNTWCPDRPRTVSS------
MUL_5004|M.ulcerans_Agy99 TSRAGLTNTWCPDRPRTVSS------
MAB_3837|M.abscessus_ATCC_1997 AAEVGLRALR----------------
MSMEG_1420|M.smegmatis_MC2_155 VARPGLDALQPAH-------------
TH_3524|M.thermoresistible__bu LVRPTLDRIERESRTVANPVRRRDVV
MLBr_02568|M.leprae_Br4923 LFWHGLKGAPADRDFGPSIVAG----
: