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DAARVVISRVGYAETRVIDITTEAGKSVGVFYNYFTDKAELLRTMVDEFRDDAYARGDTVATSDRPPHEV IRDIVTVYWTTYREHAPVLSGVFQAAQVDPTFVDYWRNLRAPARTMIANNIRHLQARGYCPGMDPDITAS AIGAMLDYFCYVWLVEGGERGRSAVTDEEAIDTLARIWFNALWWKSEGAHGAT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0314c | - | - | 100% (194) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4332 | - | 1e-27 | 34.59% (185) | transcriptional regulator TetR |
| M. abscessus ATCC 19977 | MAB_0984c | - | 1e-07 | 21.98% (182) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0279c | - | 2e-29 | 36.84% (190) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_4467 | - | 4e-22 | 32.07% (184) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0273c | - | 2e-29 | 36.84% (190) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_02677 | - | 1e-05 | 39.06% (64) | putative TetR-family transcriptional regulator |
| M. marinum M | MMAR_0533 | - | 1e-27 | 35.71% (182) | transcriptional regulatory protein |
| M. avium 104 | MAV_4886 | - | 5e-28 | 35.48% (186) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_0606 | - | 7e-26 | 34.07% (182) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0641 | - | 6e-23 | 33.15% (184) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_1197 | - | 2e-26 | 35.71% (182) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_0406 | - | 2e-25 | 32.09% (187) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0279c|M.bovis_AF2122/97 -------------MPDFPTQRGRRTQAAIDAAARTVVVRNGILATTVADI
Rv0273c|M.tuberculosis_H37Rv -------------MPDFPTQRGRRTQAAIDAAARTVVVRNGILATTVADI
MMAR_0533|M.marinum_M -------------MPEFPTHRGRQTQAAIDTAARTVIARKGILATTIADI
MUL_1197|M.ulcerans_Agy99 -------------MPEFPTHRGRQTQAAIDTAARTVIARKGILATTIADI
MAV_4886|M.avium_104 MSTAASPADRPGRPAALPTHRGRRTRAAIDMAARTVIARKGVLATTIADI
MSMEG_0606|M.smegmatis_MC2_155 --------MTVSPRDQLPTARGRQTQAAIDAAARAVISRKGILATTIADI
Mvan_0406|M.vanbaalenii_PYR-1 --------MSISPREELPTVRGRQTQAAIDMAARSVIARKGILATTVADI
Mflv_4467|M.gilvum_PYR-GCK ---------MPPGSSDALSAKGRQTRDALAQAARKLFAERGFHGTTLSDI
TH_0641|M.thermoresistible__bu ------------MAAETLSSKGRQTRLALEQAARKLFAERGFHGTTLADI
MAB_0314c|M.abscessus_ATCC_199 -----------------------------MDAARVVISRVGYAETRVIDI
MLBr_02677|M.leprae_Br4923 ----------MESQRRTQEERSTATRDALTLARHRLWRLRGYAEVGTPEI
* : : * . :*
Mb0279c|M.bovis_AF2122/97 TAEAGRSAASFYNYYDSKEAMVRQWALRFRDDANQR-ALSVIRH-GLSDR
Rv0273c|M.tuberculosis_H37Rv TAEAGRSAASFYNYYDSKEAMVRQWALRFRDDANQR-ALSVIRH-GLSDR
MMAR_0533|M.marinum_M AAEAGRSAASFYNYYDSKEAMVRQWALRFRDEVNQR-ALSVTSH-GLSNR
MUL_1197|M.ulcerans_Agy99 AAEAGRSAASFYNYYDSKEAMVRQWALRFRDEVNQR-ALSVTSH-GLSNR
MAV_4886|M.avium_104 AAEAGRSAASFYNYYDSKEAMVRQWALRFRDEANQR-ARSATRH-GLSDR
MSMEG_0606|M.smegmatis_MC2_155 AAEANRSTASFYNYYDSKEAMVHEWALRFRDEARDR-AQAAREP-GLTNW
Mvan_0406|M.vanbaalenii_PYR-1 AGEAGRSTASFYNYYDSKEAMVREWAVRFRDEARTR-SLSAARP-GLSNW
Mflv_4467|M.gilvum_PYR-GCK TSAAGKSPAAFYRYFSDKEDLLAALAESFLHEVVAPSGLSVPLP-ESPDD
TH_0641|M.thermoresistible__bu TSAAGKSPAVFYRYFVDKEDLLAALAESFLREVLAPGWLSVRLP-DSPDD
MAB_0314c|M.abscessus_ATCC_199 TTEAGKSVGVFYNYFTDKAELLRTMVDEFRDDAYAR-GDTVATS-DRPPH
MLBr_02677|M.leprae_Br4923 AKEADTTRGAVYHQFTDKAALFRDVVETVEQDAMAQIASVVASSGAKTPV
: *. : . .*. : .* :. . . :. . .
Mb0279c|M.bovis_AF2122/97 ERAYEAAAA-HWYTYRNRLAEAISVSQLAMVSDDFAQYWSEICQIPISFI
Rv0273c|M.tuberculosis_H37Rv ERAYEAAAA-HWYTYRNRLAEAISVSQLAMVSDDFAQYWSEICQIPISFI
MMAR_0533|M.marinum_M ERAYEAAAA-HWNTYRNRLAEMVSVSQLAMVNEDFAQQWADMCAIPISFI
MUL_1197|M.ulcerans_Agy99 ERSYEAAAA-HWNTYRNRLAEMVSVSQLAMVNEDFAQQCADMCAIPISFI
MAV_4886|M.avium_104 DRAYTAAAA-HWHTYRNRLAEVISVSQLAMVNDDFARYWAEICAIPISFI
MSMEG_0606|M.smegmatis_MC2_155 ERSYQAVSA-HWATYRHRLAEIISVSQLAMVSDDFAQYWAEICELPISLI
Mvan_0406|M.vanbaalenii_PYR-1 ERSYQAAAA-HWNTYRNRLAEIIAVSQMAMISDDFAEYWNEICSLPIALI
Mflv_4467|M.gilvum_PYR-GCK DAFFTAVVTGYWTMFKQNIGIMIAVAQLAATQPRFTLVQNEFRRFGMDIV
TH_0641|M.thermoresistible__bu DEFFTTVVGGYWNMFKQNIGIMIAVDQLAATQQRFADVQNEFRRFGMDIV
MAB_0314c|M.abscessus_ATCC_199 EVIRDIVTV-YWTTYREHAPVLSGVFQAAQVDPTFVDYWRNLRAPARTMI
MLBr_02677|M.leprae_Br4923 DAIRAKVDAWLEGLADPQVRQLILLYAPSVLGWAAFRDVAQHYSLGMTEQ
: . . : : :
Mb0279c|M.bovis_AF2122/97 TETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRR------
Rv0273c|M.tuberculosis_H37Rv TETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRR------
MMAR_0533|M.marinum_M KETVKRAQAEGYCPGDDPQLVAEAIVAMFNQFCYIQLSGSRTK-------
MUL_1197|M.ulcerans_Agy99 KETVKRAQAEGYCPGDDPQLVAEAIVAMFNQFCYVQLSGSRTK-------
MAV_4886|M.avium_104 AESVRRAQARGYCRDDDPQLIAEAIVAMFNQFCYIQLGSARSG-------
MSMEG_0606|M.smegmatis_MC2_155 TDMIKHAQRQGFCPDDDPHLTAVALVSMLNQFCYTKLSGGNAD-------
Mvan_0406|M.vanbaalenii_PYR-1 TSLVKQAQREGFCPEDDARLVAVALVSMLNQFCYTQLSGVNADA------
Mflv_4467|M.gilvum_PYR-GCK AASVRRAQEQGYGTELNPEHTAAAIALLFENFTTVFVGASGLG-------
TH_0641|M.thermoresistible__bu AASVRHAQQQGYGTDLDPQHIAAAIALMFENFTAVFVGRGGPG-------
MAB_0314c|M.abscessus_ATCC_199 ANNIRHLQARGYCPGMDPDITASAIGAMLDYFCYVWLVEGGERG------
MLBr_02677|M.leprae_Br4923 QLLSEASRARQLAQPLDHVLIGKLYESAMAIRRHHRLPEASPARNQTGAA
. : . : . : :
Mb0279c|M.bovis_AF2122/97 ----GQPDDQACIQTLANIYYRAIYSKEDSSN--------------
Rv0273c|M.tuberculosis_H37Rv ----GQPDDQACIQTLANIYYRAIYSKEDSSN--------------
MMAR_0533|M.marinum_M -----EPDDLACIQTLANIYYRAIYGVEVS----------------
MUL_1197|M.ulcerans_Agy99 -----EPDDLACIQTLANIYYRAIYGVEVS----------------
MAV_4886|M.avium_104 -----EPDDQACIRTLANIYYRAIYGREEEPQS-------------
MSMEG_0606|M.smegmatis_MC2_155 -----DVDDTACITTLANVFYRTIYHRGVPQP--------------
Mvan_0406|M.vanbaalenii_PYR-1 ---SADIDDEACIKTLADIFYRTIYYPENGQP--------------
Mflv_4467|M.gilvum_PYR-GCK ----VQMTDQDAIATLSRIWKKTLYGY-------------------
TH_0641|M.thermoresistible__bu ----LQISDADAVRTLATIWKKTLYGC-------------------
MAB_0314c|M.abscessus_ATCC_199 ---RSAVTDEEAIDTLARIWFNALWWKSEGAHGAT-----------
MLBr_02677|M.leprae_Br4923 PTHREHVARPSCEALTRHIRHRSTRTRSHRGKRGELLPRAATSSLL
. : .: