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MPSVTRKPQANREERRERIERALLDATDRLMSDGTSFTELSVDRLATEAGISRASFYIYFEDKGHLLRRL AAQVFDDLAHEAQQWWGVAGRRNPGDVHTAMSGIIASYRRHQPVLVALNEMSAYDPLVAQTYRDLLTGIS AQLARVIDEGQADGSIRAQLPAETTASTLTWMVERTCHQNLPSRPASYDAELADTLTEIVWGALYLRPAS TDR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4622 | - | - | 100% (213) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6441 | - | 1e-10 | 30.14% (209) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_3425 | - | 5e-10 | 26.85% (216) | TetR-family protein transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3885 | ethR | 6e-11 | 29.02% (193) | transcriptional regulatory repressor protein (TETR-family) |
| M. gilvum PYR-GCK | Mflv_2639 | - | 8e-83 | 73.30% (206) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3855 | ethR | 7e-11 | 29.02% (193) | transcriptional regulatory repressor protein (TETR-family) |
| M. leprae Br4923 | MLBr_00064 | - | 1e-10 | 26.47% (204) | putative transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3422c | - | 4e-11 | 23.81% (147) | TetR family transcriptional regulator |
| M. marinum M | MMAR_3762 | - | 1e-87 | 74.29% (210) | AcrR family transcriptional regulator |
| M. avium 104 | MAV_1733 | - | 9e-87 | 73.36% (214) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2600 | - | 4e-11 | 25.76% (198) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_3708 | - | 2e-87 | 73.81% (210) | AcrR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5684 | - | 2e-09 | 25.24% (206) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3885|M.bovis_AF2122/97 MTTSAASQAS---------LPRGRRTARPSGDDRELAILATAENLLED-R
Rv3855|M.tuberculosis_H37Rv MTTSAASQAS---------LPRGRRTARPSGDDRELAILATAENLLED-R
MLBr_00064|M.leprae_Br4923 MINSTAGQTS---------QSRSRRSTRPSGDDRELAILATAEQLLED-R
Mvan_5684|M.vanbaalenii_PYR-1 MRSSTRCKVSPVTATSPTRPARGRRAARPSGDDRELAILETAERLLAD-R
MSMEG_4622|M.smegmatis_MC2_155 MPSVTRKP------------QANREERR---ERIERALLDATDRLMSDGT
MAV_1733|M.avium_104 MPSVTRTPPG--------RRSPGREQRR---EQLERRLLDATERLMRDGA
MMAR_3762|M.marinum_M MASITRNA------------QANRRQRR---EQMECRLLEATERLMNNGA
MUL_3708|M.ulcerans_Agy99 MASITRNA------------QANRRQRR---EQMECRLLEATERLMNNGA
Mflv_2639|M.gilvum_PYR-GCK MPSVTRKA------------QATRQERR---EQIERRLLEATDRLMADGA
TH_2600|M.thermoresistible__bu MSKPRVRN------------RYSSGPTR--GEQRRERLLQALEDLLAS-R
MAB_3422c|M.abscessus_ATCC_199 MVSPARSG----------------TQTR--GDRQRDAIMTAVAELIAENH
* . * : . :: : *: .
Mb3885|M.bovis_AF2122/97 PLADISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNQADMALQTL
Rv3855|M.tuberculosis_H37Rv PLADISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNQADMALQTL
MLBr_00064|M.leprae_Br4923 PLTEISVDYLAKSAGISRPTFYFYFASKEAVLLTLLDRVFNKANAALETL
Mvan_5684|M.vanbaalenii_PYR-1 SLAEISVDDLAKGAGISRPTFYFYFASKDAVLLTLLERVIAEADAALAQL
MSMEG_4622|M.smegmatis_MC2_155 SFTELSVDRLATEAGISRASFYIYFEDKGHLLRRLAAQVFDDLAHEAQQW
MAV_1733|M.avium_104 SFTELSVDRLAGAAGISRASFYIYFEDKGHLLRRLASRVFGELTDGARRW
MMAR_3762|M.marinum_M SFTELSVDRLATEAGISRASFYIYFDDKGHLLRRLAGQVFDDLATGAQHW
MUL_3708|M.ulcerans_Agy99 SFTELSVDRLATEAGISRASFYIYFDDKGHLLRRLAGQVFDDLATGAQHW
Mflv_2639|M.gilvum_PYR-GCK SITELSVDRLASEAGISRASFYIYFEDKGHLLRRLASQVFGDLADAAQRW
TH_2600|M.thermoresistible__bu PFAAIEVGDIARAAGLSRSAFYFYFPSKAAAVGAMLGDVFGEISDVLDKW
MAB_3422c|M.abscessus_ATCC_199 SFADLSVSAISERAGVGRSGFYFYFDSKYSVLAQMVGDAFAELDELTHYF
.:: :.*. :: **:.*. **:** .* : : .. .
Mb3885|M.bovis_AF2122/97 AENPADTDRENM-WRTGINVFFETFGSHKAVTRAGQAARATSVEVAELWS
Rv3855|M.tuberculosis_H37Rv AENPADTDRENM-WRTGINVFFETFGSHKAVTRAGQAARATSVEVAELWS
MLBr_00064|M.leprae_Br4923 IKN-RDNKRGNK-WRTGINVFFETFGSHKAVTCAGQVTRDN-TEVRKLWS
Mvan_5684|M.vanbaalenii_PYR-1 IAE-RSSDRRTI-WRRGINVFFETFGAHRAVCATTVGVKSTNSEARELWS
MSMEG_4622|M.smegmatis_MC2_155 WGVAGRRNPGD--VHTAMSGIIASYRRHQPVLVALNEMSAYDPLVAQTYR
MAV_1733|M.avium_104 WSVAGRHDPDD--VRAAMTRIIATYRRHQAVLVALNEMSGYDPLTAQTYR
MMAR_3762|M.marinum_M WDVAWRHDPDD--VRAAMRAIIARYRRHQPILIALNEMAGYDPQTAQTYR
MUL_3708|M.ulcerans_Agy99 WDVAWRHDPDD--VRAAMCAIIARYRRHQPILIALNEMAGYEPQTAQTYR
Mflv_2639|M.gilvum_PYR-GCK WSVASRLDPED--VRVAMAAIIAAYRQHQPVLVALNEMAPYDPAVAETYR
TH_2600|M.thermoresistible__bu TELGDSVAARRREVYDSFERVVAIWRQHAPLMAAMFDAASTDAEVRAMFE
MAB_3422c|M.abscessus_ATCC_199 APRGEEETPEQF-AHRMVGSAAASFAHNDPLMKACQEARITDPTIAGLLD
. : : .: :
Mb3885|M.bovis_AF2122/97 TFMQKWIAYTAAVIDAERDR-GAAPRTLPAHELATALNLMNERTLFASFA
Rv3855|M.tuberculosis_H37Rv TFMQKWIAYTAAVIDAERDR-GAAPRTLPAHELATALNLMNERTLFASFA
MLBr_00064|M.leprae_Br4923 TFMQKWISYTAAVIDAERKR-GVAPDTLPATELATALNLMNERALFASFT
Mvan_5684|M.vanbaalenii_PYR-1 RSMQRWIDHIAAVIEAERAD-GAAPVTVPARELSTALNLMNESVMTATFT
MSMEG_4622|M.smegmatis_MC2_155 DLLTGISAQLARVIDEGQAD-GSIRAQLPAETTASTLTWMVERTCHQNLP
MAV_1733|M.avium_104 EILTGISGQLTRVIEDGQAD-GSIRPRLAAATTASALTWMVERACQQNLP
MMAR_3762|M.marinum_M DILTAISARLARVIEDGQAD-GSIRPELSATTTANALTWMVERTCHQNLP
MUL_3708|M.ulcerans_Agy99 DILTAISARLARVIEDGQAD-GSIRPELSATTTANALTWMVERTCHQNLP
Mflv_2639|M.gilvum_PYR-GCK DLIAEISTRFEAVIVEGQKA-GTIRPQLPPDITAHTLVLMVERTCQQNLP
TH_2600|M.thermoresistible__bu GHIDSFVDGSAARIRHERAV-GEAPDGPDPEALARVLVGMNVKALERDMR
MAB_3422c|M.abscessus_ATCC_199 DLTDVVIEKILKIAETEVKERGAQPISDDLPALVRSLVALTASTVSGDSS
* * : .
Mb3885|M.bovis_AF2122/97 GEQPSVPEARVLDTLVHIWVTSIYGENR----
Rv3855|M.tuberculosis_H37Rv GEQPSVPEARVLDTLVHIWVTSIYGENR----
MLBr_00064|M.leprae_Br4923 AEQPHVPESRVLDTLVHIWVSSIYNEIR----
Mvan_5684|M.vanbaalenii_PYR-1 GHQPAIPDDRVLDNLVHIWTTSIYGKTD----
MSMEG_4622|M.smegmatis_MC2_155 S-RPASYDAELADTLTEIVWGALYLRPASTDR
MAV_1733|M.avium_104 A-QPSAYDAELADTLAEIVWGALYLKPASGS-
MMAR_3762|M.marinum_M S-RPPEFDAELADTLSEIVWGALYLTSTSLR-
MUL_3708|M.ulcerans_Agy99 S-RPPEFDAELADTLSEIVWGALYLTSTSLR-
Mflv_2639|M.gilvum_PYR-GCK S-RPTSFDTELADVLTEIVWGSLYLTNPAG--
TH_2600|M.thermoresistible__bu AITSGAPADADLPRVLAFVWGRVLYDA-----
MAB_3422c|M.abscessus_ATCC_199 FVGRNTDPARAIATVETLWRVSLLGR------
: : :