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MPAAAKSRPADARGRLIEATAKVMRDEGYAAATSRRVAAEAGVKQALVYYYFPTMDDLFVEVLRVGGESS LEHMRAALTNDDPLRALWLINSEAGRTGLNAEFMALANHRKAIRVELKAYAERVRDIETAAVTVALRANG VDLQEHPPVVVSMLIAQIARSLCNEDAVGVTLGHEEMRAWVDRQLALLAAEPGG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1588 | - | - | 100% (194) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2518 | - | 5e-34 | 40.21% (194) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1270 | - | 2e-27 | 38.32% (167) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1561 | - | 1e-06 | 25.81% (186) | transcriptional regulator |
| M. tuberculosis H37Rv | Rv1534 | - | 1e-06 | 25.81% (186) | transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3372 | - | 1e-08 | 29.75% (158) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4693 | - | 2e-40 | 46.99% (183) | transcriptional regulator |
| M. avium 104 | MAV_0847 | - | 8e-75 | 78.86% (175) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6032 | - | 2e-64 | 64.67% (184) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2984 | - | 2e-77 | 79.89% (179) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_0675 | - | 1e-07 | 40.98% (61) | transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5169 | - | 3e-89 | 85.20% (196) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1588|M.gilvum_PYR-GCK ------------MPAAAKSR------PAD--ARGRLIEATAKVMRDEGYA
Mvan_5169|M.vanbaalenii_PYR-1 ------------MAASPKGR------GSDPNARQRLIEATARVMRDEGYA
MAV_0847|M.avium_104 -----------------------------------MIEATARLMREEGYA
TH_2984|M.thermoresistible__bu ------------MPTTRQNRRSSDSGSVDTGARSRLIEATAQIMREEGYA
MSMEG_6032|M.smegmatis_MC2_155 ------------MARVVKAG-PRTAKDKDAGTRQRLIEATAQVIRDEGYA
MMAR_4693|M.marinum_M ------------MTSARRIG------APDAKNRGVLLDTAEELMIEEGYA
Mb1561|M.bovis_AF2122/97 ------------MSRASARRRRAVSDEDKSQRRDEILAAAKIVFAHKGFH
Rv1534|M.tuberculosis_H37Rv ------------MSRASARRRRAVSDEDKSQRRDEILAAAKIVFAHKGFH
MUL_0675|M.ulcerans_Agy99 ------------MPTAAERG---------AQTRAALMAAAVAVIAERGWG
MAB_3372|M.abscessus_ATCC_1997 MAILAFGEGFDIMSSSRLQPRKQPRQDRAEATRRRILEAAAHVFADFGYA
:: :: :: . *:
Mflv_1588|M.gilvum_PYR-GCK AATSRRVAAEAGVKQALVYYYFPTMDDLFVEVLRVGGESSLEHMRAALT-
Mvan_5169|M.vanbaalenii_PYR-1 AATSRRVAAEAGVKQALVYYYFPTMDDLFVEVLRAGGESALEHMRAALT-
MAV_0847|M.avium_104 AATSRRVAAEAGVKQALVYYYFPTMDDLFVEVLRAGAESALTRMRALLT-
TH_2984|M.thermoresistible__bu AATSRRVAARAGVKQALVYYYFPTMDDLFVEVLRTGAEAALERMRTALT-
MSMEG_6032|M.smegmatis_MC2_155 AATTRRIAAQAGVRSALVYYYFDTLDDLYIAVLRNGADVALERMREAVA-
MMAR_4693|M.marinum_M AVTSRRVASEAGLKPQLVHYYFRTMEELFLELFRRRAEEGLRAQAQALQ-
Mb1561|M.bovis_AF2122/97 ATTVADIAKQAGLAYGLIYWYFDSKDDLFHALMAGEEEALRAHVAAELAR
Rv1534|M.tuberculosis_H37Rv ATTVADIAKQAGLAYGLIYWYFDSKDDLFHALMAGEEEALRAHVAAELAR
MUL_0675|M.ulcerans_Agy99 AATTRMVAERAGLPPGLVHYHFASLNDLLIDAALQAAREEAAQVLDGLAG
MAB_3372|M.abscessus_ATCC_1997 AGTTNRIAERAEISIGSLYQYFPNKDAILVELMTAHTHRGFALIHQHLAA
* * :* .* : :: :* . : : :
Mflv_1588|M.gilvum_PYR-GCK ----NDDPLRALWLINSEAGRTGLNAEFMALANHRKAIRVELKAYAERVR
Mvan_5169|M.vanbaalenii_PYR-1 ----NDDPLHALWLINNDASRTGLNTEFMALANHRKAIRVELRAYAERVR
MAV_0847|M.avium_104 ----EDDPLQALWLMNSDTALTALNAEFMALANHRKAIGAELKAYAERVR
TH_2984|M.thermoresistible__bu ----DDDPLRALWELNSDTRLTSLNSEFIALANHRKAIRAELKAYAERVR
MSMEG_6032|M.smegmatis_MC2_155 ----ADDPLRALWLLNSDARLSVLNTEFMALANHRKTIGAELKAYSERVR
MMAR_4693|M.marinum_M ----SPKPLWALWRLGSDPAFARISMEFMALANHRKALRAEIAHYAERFR
Mb1561|M.bovis_AF2122/97 VGGSTEAPLRALLQAAVQATFEFFETDKATVKLLFRDAYALGGRFEEHLG
Rv1534|M.tuberculosis_H37Rv VGGSTEAPLRALLQAAVQATFEFFETDKATVKLLFRDAYALGGRFEEHLG
MUL_0675|M.ulcerans_Agy99 ----DSSSQGIDRLIDAVSSYDVDDRNQNPAILVFGEMLLAATRYERLRM
MAB_3372|M.abscessus_ATCC_1997 G---LPDTIEDTVRVFVGSAIANHRDSPRLHRVLFEEAPRPPEFLAMLHR
. . .
Mflv_1588|M.gilvum_PYR-GCK --------DIETAAVTVALRANGVDL-QEHPPVVVSMLIAQIAR-SLCNE
Mvan_5169|M.vanbaalenii_PYR-1 --------DIETAAVTVALRANGVDL-DEHPPVVISMLIAQVAR-SLCNE
MAV_0847|M.avium_104 --------DIETAAATMVLRANGIDL-EEYPPVAISMLIAQAAR-SLCNE
TH_2984|M.thermoresistible__bu --------DIETAAVTVALRARGVDL-DDHPPVAVSMLIAQIAR-SLCNE
MSMEG_6032|M.smegmatis_MC2_155 --------DIETTAVAMVMRTHGIDT-EQYPPVVMSMLLTQSAR-SLSNE
MMAR_4693|M.marinum_M --------DEQRRVITAALQRYGVDS-QDVPPVVWTVLMASLSR-FLVLE
Mb1561|M.bovis_AF2122/97 GIYERFIDDIEAVVVAAQRRGEVVEAPSRMAAYTLAALVGQLAHRRLNTD
Rv1534|M.tuberculosis_H37Rv GIYERFIDDIEAVVVAAQRRGEVVEAPSRMAAYTLAALVGQLAHRRLNTD
MUL_0675|M.ulcerans_Agy99 G------LAEILGDYRSTLRQWLADQGGAIDPEATAALMFAAID-GLVLH
MAB_3372|M.abscessus_ATCC_1997 SED----AVIAAAEAVLAAHPEVRVTETDTAARMVVATIESLVHRLIAGP
: . : :
Mflv_1588|M.gilvum_PYR-GCK DAVGVTLGHEEMRAWVDRQLALLAAEPGG--------
Mvan_5169|M.vanbaalenii_PYR-1 VAVGVTLGHDEMRAYVERQLKLLAPVTGG--------
MAV_0847|M.avium_104 KAVGVTQGHDELRAFVQRQLSRLTAPAVASTTSA---
TH_2984|M.thermoresistible__bu RAVGVTLGHDELRAFMDRLMTQLGAPARASAPPPAQR
MSMEG_6032|M.smegmatis_MC2_155 EAVGVTQGHAEFRAFVDQILQRFTPTEPAT-------
MMAR_4693|M.marinum_M KALGMSGGHAETIELVESYLRRLEGEP----------
Mb1561|M.bovis_AF2122/97 DNVTAAQVADFVVSLVLDGLRPRALAVGARGGRAART
Rv1534|M.tuberculosis_H37Rv DNVTAAQVADFVVSLVLDGLRPRALAVGARGGRAART
MUL_0675|M.ulcerans_Agy99 RVIDPRLRTLAIRPTLRRLAGLPTAQTDERTPS----
MAB_3372|M.abscessus_ATCC_1997 RPIDPQLFEDQLVDMLTRYLTG---------------
: :