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PTAAERGAQTRAALMAAAVAVIAERGWGAATTRMVAERAGLPPGLVHYHFASLNDLLIDAALQAAREEAA QVLDGLAGDSSSQGIDRLIDAVSSYDVDDRNQNPAILVFGEMLLAATRYERLRMGLAEILGDYRSTLRQW LADQGGAIDPEATAALMFAAIDGLVLHRVIDPRLRTLAIRPTLRRLAGLPTAQTDERTPS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0675 | - | - | 100% (201) | transcriptional regulator |
| M. ulcerans Agy99 | MUL_0488 | - | 4e-10 | 28.73% (181) | hypothetical protein MUL_0488 |
| M. ulcerans Agy99 | MUL_4301 | - | 2e-07 | 30.08% (123) | DeoR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0335 | - | 5e-10 | 30.46% (197) | TetR/AcrR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1610 | - | 2e-09 | 27.98% (168) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0328 | - | 5e-10 | 30.46% (197) | TetR/AcrR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3397 | - | 5e-16 | 32.79% (183) | hypothetical protein MAB_3397 |
| M. marinum M | MMAR_0923 | - | 1e-107 | 98.50% (200) | transcriptional regulator |
| M. avium 104 | MAV_4851 | - | 2e-09 | 30.39% (181) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5850 | - | 8e-10 | 28.65% (171) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2883 | - | 3e-10 | 42.86% (70) | PUTATIVE putative transcriptional regulator, TetR family |
| M. vanbaalenii PYR-1 | Mvan_4140 | - | 3e-09 | 41.43% (70) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_0675|M.ulcerans_Agy99 ------------------MPTAAERGAQTRAALMAAAVAVIAERGWGAAT
MMAR_0923|M.marinum_M ------------------MPTAAERGAQTRAALMAAAVAVIAERGWGAAT
TH_2883|M.thermoresistible__bu ----------MSSSSPSRRSRVGGSDTATRRALIKATADVMLEEGYAAAT
Mvan_4140|M.vanbaalenii_PYR-1 ----------MTSPR-----RIGAPDAKNRVVLLDAAEQLLIEEGYAAVT
Mb0335|M.bovis_AF2122/97 ----------------------MQQQRTNRDKLLDGALACLRERGYGNTS
Rv0328|M.tuberculosis_H37Rv ----------------------MQQQRTNRDKLLDGALACLRERGYGNTS
Mflv_1610|M.gilvum_PYR-GCK --------------MLKVTAAVTPKGERRRYALVSAAADLLCEGGFDAVR
MSMEG_5850|M.smegmatis_MC2_155 -----------------MTAAVTPKGERRRYALIRAAAELLCEGGFDAVR
MAB_3397|M.abscessus_ATCC_1997 -------------MTNLADRPNSARGDRRRTQLVRAGVELLSEGGWPAVT
MAV_4851|M.avium_104 MSIAAGQQPGRPAGPTRRTTAPRKRGDDTRARIIDETVRCIIEEGFAAAT
* :: : * *: .
MUL_0675|M.ulcerans_Agy99 TRMVAERAGLPPGLVHYHFASLNDLLIDAAL----QAAREEAAQVLDGLA
MMAR_0923|M.marinum_M TRMVAERAGLPPGLVHYHFASLNDLLIDAAL----QAAREEAAQVLDGLA
TH_2883|M.thermoresistible__bu SRRVAARAGVKPALVHYYFPSMDDLFVAVFR----AGAEATLQRQRNAFA
Mvan_4140|M.vanbaalenii_PYR-1 SRRVADRAGLKPQLVHYYFRTMEDLFLAVFH----RRAEEGLAVLSTALA
Mb0335|M.bovis_AF2122/97 SRDIARAAGVNIASINYHFGSKDALLDDALG----RCFSTWNQRVQEAFD
Rv0328|M.tuberculosis_H37Rv SRDIARAAGVNIASINYHFGSKDALLDDALG----RCFSTWNQRVQEAFD
Mflv_1610|M.gilvum_PYR-GCK HRAVARRAGLPLASTTYYFSSLDDLIANAVEHVGSRETEQLRHRVAALSR
MSMEG_5850|M.smegmatis_MC2_155 HRAVARRAGLPLASTTYYFSSLDDLIAKAVEYIGMREANQLRESVASLSR
MAB_3397|M.abscessus_ATCC_1997 TRAVAARAGTNPGLIHYHFGGLPGLHCAVAR---ETCELVISPLVATFLD
MAV_4851|M.avium_104 AKHVAERAGVTWGVIQYHFGDRNGLLMAVVD-------DGVARLVESLSS
: :* ** *:* * .
MUL_0675|M.ulcerans_Agy99 GDSSSQGIDRLIDAVSSYDVDDRNQ---NPAILVFGEMLLAATRYERLR-
MMAR_0923|M.marinum_M GDSPSQGIDRLIDAVSSYDVDDRNQ---NPAILVFGEMLLAATRYERLR-
TH_2883|M.thermoresistible__bu GDRPLHALWELNST-QGAQLFMEFMALGNHRKAIRREIAAYAEQYGELEH
Mvan_4140|M.vanbaalenii_PYR-1 SPQPLWALWRFSTAPEATRLTMEFMGLANHRKALRAEIVYYAERFRQEQN
Mb0335|M.bovis_AF2122/97 HSRAAGPAGQILAVLEATVDSFEQIRPAVYACVESYAPALRSEALRERLA
Rv0328|M.tuberculosis_H37Rv HSRAAGPAGQILAVLEATVDSFEQIRPAVYACVESYAPALRSEALRERLA
Mflv_1610|M.gilvum_PYR-GCK RRRGAESTADILVDLLVGDNP-ERVTEQMISRYERYIACARQPGLRDIQR
MSMEG_5850|M.smegmatis_MC2_155 RRRGAESTAEILVDLLVGDEPGARVTEELISRYERYIACARQPGLRDIQR
MAB_3397|M.abscessus_ATCC_1997 APDTRAALHAMRDALPQAASDDNAMHLAVELIAGATRDADLGAALGTKLK
MAV_4851|M.avium_104 ADVSELPLRQRVEVVIDTAWSCYSSPTSMAAFEILHATRGALGDSSRRHL
MUL_0675|M.ulcerans_Agy99 MGLAEILGDYRSTLRQWLADQGGAIDP--EATAALMFAAIDGLVLHRVID
MMAR_0923|M.marinum_M MGLAEILGDYRSALRQWLADQGGAIDP--EATAALMFAAIDGLVLHRVID
TH_2883|M.thermoresistible__bu AAVATALRAHGMDTEEFPPAAIAMILT--SVARIMLIEQNLGIERSHAAV
Mvan_4140|M.vanbaalenii_PYR-1 RAIADALQRYGTDFTDVPPVVWTVFAT--SVSQALVMERALGMDTGHAET
Mb0335|M.bovis_AF2122/97 AGYADVRQHSVDLAGAALAGTDIAPPENLSTIVSVLMAVIDGLMIQWIAD
Rv0328|M.tuberculosis_H37Rv AGYADVRQHSVDLAGAALAGTDIAPPENLSTIVSVLMAVIDGLMIQWIAD
Mflv_1610|M.gilvum_PYR-GCK R----ILRQRSDAVVEVVERSGRSVR---AELVTALVCAVDGAVVAALVG
MSMEG_5850|M.smegmatis_MC2_155 R----ILQQRTDAVVEAVERSGRSVR---AELVTALVCAVDGAVVASLVD
MAB_3397|M.abscessus_ATCC_1997 EVRAEIADHVRLRHPDWPRRRAAGMAT-------LIVAFMDGLVLHHTVD
MAV_4851|M.avium_104 LDMNAAIGQLGRLITTDPANAG---------VAEVIWATLRGVVLAQMVI
: *
MUL_0675|M.ulcerans_Agy99 PRLRTLAIRPTLRRLAGLPTAQTDERTPS--
MMAR_0923|M.marinum_M PRLRTLAIRPALRRLAGLPTAQTDERTPP--
TH_2883|M.thermoresistible__bu REF----VGRYLDRFD-VPAGAHDADS----
Mvan_4140|M.vanbaalenii_PYR-1 FAF----CEEWIRRLEGDPLPPLDQRA----
Mb0335|M.bovis_AF2122/97 PSATP-RSTEVIRALASIGAVVTSQLR----
Rv0328|M.tuberculosis_H37Rv PSATP-RSTEVIRALASIGAVVTSQLR----
Mflv_1610|M.gilvum_PYR-GCK DGDGP-RATARATLIDVIDVLAPFN------
MSMEG_5850|M.smegmatis_MC2_155 EGDGP-RASARATLIDVIDVLAPVDDRAVRV
MAB_3397|M.abscessus_ATCC_1997 PNIET------AEAFSLLESLLDEE------
MAV_4851|M.avium_104 GTTVD----WSLERRALIDMVTRVLQ-----