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AASPKGRGSDPNARQRLIEATARVMRDEGYAAATSRRVAAEAGVKQALVYYYFPTMDDLFVEVLRAGGES ALEHMRAALTNDDPLHALWLINNDASRTGLNTEFMALANHRKAIRVELRAYAERVRDIETAAVTVALRAN GVDLDEHPPVVISMLIAQVARSLCNEVAVGVTLGHDEMRAYVERQLKLLAPVTGG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5169 | - | - | 100% (196) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4140 | - | 1e-35 | 42.86% (189) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5860 | - | 4e-08 | 30.16% (126) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3093 | - | 1e-06 | 35.43% (127) | DeoR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1588 | - | 2e-89 | 85.20% (196) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3066 | - | 1e-06 | 35.43% (127) | DeoR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3372 | - | 3e-09 | 30.61% (147) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4693 | - | 4e-39 | 46.41% (181) | transcriptional regulator |
| M. avium 104 | MAV_0847 | - | 6e-76 | 80.68% (176) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6032 | - | 4e-64 | 62.30% (191) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2984 | - | 1e-77 | 78.33% (180) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_4875 | - | 3e-08 | 38.57% (70) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3093|M.bovis_AF2122/97 ------------MTAGSDRR-----PRDPAGRRQAIVEAAERVIARQGLG
Rv3066|M.tuberculosis_H37Rv ------------MTAGSDRR-----PRDPAGRRQAIVEAAERVIARQGLG
Mvan_5169|M.vanbaalenii_PYR-1 ------------MAASPKGR------GSDPNARQRLIEATARVMRDEGYA
Mflv_1588|M.gilvum_PYR-GCK ------------MPAAAKSR------PAD--ARGRLIEATAKVMRDEGYA
MAV_0847|M.avium_104 -----------------------------------MIEATARLMREEGYA
TH_2984|M.thermoresistible__bu ------------MPTTRQNRRSSDSGSVDTGARSRLIEATAQIMREEGYA
MSMEG_6032|M.smegmatis_MC2_155 ------------MARVVKAG-PRTAKDKDAGTRQRLIEATAQVIRDEGYA
MMAR_4693|M.marinum_M ------------MTSARRIG------APDAKNRGVLLDTAEELMIEEGYA
MAB_3372|M.abscessus_ATCC_1997 MAILAFGEGFDIMSSSRLQPRKQPRQDRAEATRRRILEAAAHVFADFGYA
MUL_4875|M.ulcerans_Agy99 ------------MTRTQLGR---PVGASGEETRQRIIVATMQCVSKVGYA
:: :: . . * .
Mb3093|M.bovis_AF2122/97 GLSHRRVAAEANVPVGSTTYYFNDLDALREAALAHAANASADLLAQWRSD
Rv3066|M.tuberculosis_H37Rv GLSHRRVAAEANVPVGSTTYYFNDLDALREAALAHAANASADLLAQWRSD
Mvan_5169|M.vanbaalenii_PYR-1 AATSRRVAAEAGVKQALVYYYFPTMDDLFVEVLRAGGES---ALEHMRAA
Mflv_1588|M.gilvum_PYR-GCK AATSRRVAAEAGVKQALVYYYFPTMDDLFVEVLRVGGES---SLEHMRAA
MAV_0847|M.avium_104 AATSRRVAAEAGVKQALVYYYFPTMDDLFVEVLRAGAES---ALTRMRAL
TH_2984|M.thermoresistible__bu AATSRRVAARAGVKQALVYYYFPTMDDLFVEVLRTGAEA---ALERMRTA
MSMEG_6032|M.smegmatis_MC2_155 AATTRRIAAQAGVRSALVYYYFDTLDDLYIAVLRNGADV---ALERMREA
MMAR_4693|M.marinum_M AVTSRRVASEAGLKPQLVHYYFRTMEELFLELFRRRAEE---GLRAQAQA
MAB_3372|M.abscessus_ATCC_1997 AGTTNRIAERAEISIGSLYQYFPNKDAILVELMTAHTHRGFALIHQHLAA
MUL_4875|M.ulcerans_Agy99 RATIREIARTANVTSASLYNYFPNKSELIKETIAARADA---AMPRLRRA
: ..:* * : ** . : : . :
Mb3093|M.bovis_AF2122/97 LDKDRDLAATLARLTTVYLADQDRYRTLNELYMAAAHRPELQRLARLWPD
Rv3066|M.tuberculosis_H37Rv LDKDRDLAATLARLTTVYLADQDRYRTLNELYMAAAHRPELQRLARLWPD
Mvan_5169|M.vanbaalenii_PYR-1 LTNDDPLHALWLINNDASRTGLN-----TEFMALANHRKAIRVELRAYAE
Mflv_1588|M.gilvum_PYR-GCK LTNDDPLRALWLINSEAGRTGLN-----AEFMALANHRKAIRVELKAYAE
MAV_0847|M.avium_104 LTEDDPLQALWLMNSDTALTALN-----AEFMALANHRKAIGAELKAYAE
TH_2984|M.thermoresistible__bu LTDDDPLRALWELNSDTRLTSLN-----SEFIALANHRKAIRAELKAYAE
MSMEG_6032|M.smegmatis_MC2_155 VAADDPLRALWLLNSDARLSVLN-----TEFMALANHRKTIGAELKAYSE
MMAR_4693|M.marinum_M LQSPKPLWALWRLGSDPAFARIS-----MEFMALANHRKALRAEIAHYAE
MAB_3372|M.abscessus_ATCC_1997 GLPDTIEDTVRVFVGSAIANHRDSPRLHRVLFEEAPRPPEFLAMLHRSED
MUL_4875|M.ulcerans_Agy99 AEGGGNIVDRIEAVLDECGELIREYPQLAAFEFAIRAEDGIAVDAQEGSG
: :
Mb3093|M.bovis_AF2122/97 GLLALLEPRIGRRAANAVTVFFD----GATLHALITGTPLSTDELTDAIA
Rv3066|M.tuberculosis_H37Rv GLLALLEPRIGRRAANAVTVFFD----GATLHALITGTPLSTDELTDAIA
Mvan_5169|M.vanbaalenii_PYR-1 RVRDIETAAVTVALRANGVDLDE----HPPVVISMLIAQVARSLCNEVAV
Mflv_1588|M.gilvum_PYR-GCK RVRDIETAAVTVALRANGVDLQE----HPPVVVSMLIAQIARSLCNEDAV
MAV_0847|M.avium_104 RVRDIETAAATMVLRANGIDLEE----YPPVAISMLIAQAARSLCNEKAV
TH_2984|M.thermoresistible__bu RVRDIETAAVTVALRARGVDLDD----HPPVAVSMLIAQIARSLCNERAV
MSMEG_6032|M.smegmatis_MC2_155 RVRDIETTAVAMVMRTHGIDTEQ----YPPVVMSMLLTQSARSLSNEEAV
MMAR_4693|M.marinum_M RFRDEQRRVITAALQRYGVDSQD----VPPVVWTVLMASLSRFLVLEKAL
MAB_3372|M.abscessus_ATCC_1997 AVIAAAEAVLAAHPEVRVTETDT----AARMVVATIESLVHRLIAGPRPI
MUL_4875|M.ulcerans_Agy99 QLGEVGFTAFREIIRGLVEDARRRGELAEQADTAGAIEAIYALIYGLTEL
.
Mb3093|M.bovis_AF2122/97 RLVADGPEQREVGQSAHAGRTPD-----------
Rv3066|M.tuberculosis_H37Rv RLVADGPEQREVGQSAHAGRTPD-----------
Mvan_5169|M.vanbaalenii_PYR-1 GVTLGHDEMRAYVERQLKLLAPVTGG--------
Mflv_1588|M.gilvum_PYR-GCK GVTLGHEEMRAWVDRQLALLAAEPGG--------
MAV_0847|M.avium_104 GVTQGHDELRAFVQRQLSRLTAPAVASTTSA---
TH_2984|M.thermoresistible__bu GVTLGHDELRAFMDRLMTQLGAPARASAPPPAQR
MSMEG_6032|M.smegmatis_MC2_155 GVTQGHAEFRAFVDQILQRFTPTEPAT-------
MMAR_4693|M.marinum_M GMSGGHAETIELVESYLRRLEGEP----------
MAB_3372|M.abscessus_ATCC_1997 DPQLFEDQLVDMLTRYLTG---------------
MUL_4875|M.ulcerans_Agy99 AATLPLDQFHAALSAAKGLIRGTLFRC-------
: